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Items: 1 to 20 of 112

1.
Kinetic Properties of ASC Protein Aggregation in Epithelial Cells
Jun Cheng, Andrea L. Waite, Eric R. Tkaczyk, Kevin Ke, Neil Richards, Alan J. Hunt, Deborah L. Gumucio
J Cell Physiol. Author manuscript; available in PMC 2023 Apr 2.
Published in final edited form as: J Cell Physiol. 2010 Mar; 222(3): 738–747. doi: 10.1002/jcp.22005
PMCID:
PMC10067259
AbstractArticlePDF–2.9M
2.
The central inflammasome adaptor protein ASC activates the inflammasome after transition from a soluble to an insoluble state
Evan R. Prather, Mikhail A. Gavrilin, Mark D. Wewers
J Biol Chem. 2022 Jun; 298(6): 102024. Published online 2022 May 11. doi: 10.1016/j.jbc.2022.102024
PMCID:
PMC9163591
AbstractArticlePDF–1.2M
3.
Apoptosis-associated speck-like protein containing a CARD regulates the growth of pancreatic ductal adenocarcinoma
Mitsuhito Koizumi, Takao Watanabe, Junya Masumoto, Kotaro Sunago, Yoshiki Imamura, Kozue Kanemitsu, Teru Kumagi, Yoichi Hiasa
Sci Rep. 2021; 11: 22351. Published online 2021 Nov 16. doi: 10.1038/s41598-021-01465-2
PMCID:
PMC8595714
AbstractArticlePDF–12M
4.
Aberrant Hypermethylation-Mediated Suppression of PYCARD Is Extremely Frequent in Prostate Cancer with Gleason Score ≥ 7
Toshiya Miyauchi, Masahiro Takahashi, Koji Mitsuzuka, Yuriko Saiki, Teppei Okubo, Paula M. Vertino, Akiteru Goto, Yoichi Arai, Akira Horii, Shinichi Fukushige
Dis Markers. 2021; 2021: 8858905. Published online 2021 Feb 4. doi: 10.1155/2021/8858905
PMCID:
PMC7881737
AbstractArticlePDF–1.9M
5.
Genetic disruption of the inflammasome adaptor ASC has minimal impact on the pathogenesis of Duchenne muscular dystrophy in mdx Mice
Yeh Siang Lau, Lixia Zhao, Chen Zhang, Haiwen Li, Renzhi Han
Life Sci. Author manuscript; available in PMC 2021 Sep 15.
Published in final edited form as: Life Sci. 2020 Sep 15; 257: 118069. Published online 2020 Jul 10. doi: 10.1016/j.lfs.2020.118069
PMCID:
PMC7484256
AbstractArticlePDF–1.6M
6.
Gene therapy with apoptosis-associated speck-like protein, a newly described schwannoma tumor suppressor, inhibits schwannoma growth in vivo
Sherif G Ahmed, Ahmed Abdelnabi, Casey A Maguire, Mohamed Doha, Jessica E Sagers, Rebecca M Lewis, Alona Muzikansky, Marco Giovannini, Anat Stemmer-Rachamimov, Konstantina M Stankovic, Giulia Fulci, Gary J Brenner
Neuro Oncol. 2019 Jul; 21(7): 854–866. Published online 2019 Apr 12. doi: 10.1093/neuonc/noz065
PMCID:
PMC6620641
AbstractArticlePDF–9.3M
7.
Assessment of ASC specks as a putative biomarker of pyroptosis in myelodysplastic syndromes: an observational cohort study
Ashley A Basiorka, Kathy L McGraw, Farnoosh Abbas-Aghababazadeh, Amy F McLemore, Nicole D Vincelette, Grace A Ward, Erika A Eksioglu, David A Sallman, Najla Al Ali, Eric Padron, Javier Pinilla-Ibarz, Rami Komrokji, Erico Masala, Valeria Santini, Olivier Kosmider, Michaela Fontenay, Pierre Fenaux, Lubomir Sokol, Sheng Wei, Brooke Fridley, Alan F List
Lancet Haematol. Author manuscript; available in PMC 2019 May 8.
Published in final edited form as: Lancet Haematol. 2018 Sep; 5(9): e393–e402. Published online 2018 Jul 30. doi: 10.1016/S2352-3026(18)30109-1
PMCID:
PMC6505461
AbstractArticlePDF–678K
8.
Clinical chorioamnionitis at term IX: In vivo evidence of intra-amniotic inflammasome activation
Nardhy Gomez-Lopez, Roberto Romero, Eli Maymon, Juan-Pedro Kusanovic, Bogdan Panaitescu, Derek Miller, Percy Pacora, Adi L. Tarca, Kenichiro Motomura, Offer Erez, Eunjung Jung, Sonia S. Hassan, Chaur-Dong Hsu
J Perinat Med. Author manuscript; available in PMC 2020 Apr 24.
Published in final edited form as: J Perinat Med. 2019 Apr 24; 47(3): 276–287. doi: 10.1515/jpm-2018-0271
PMCID:
PMC6445729
AbstractArticlePDF–521K
9.
The inflammasome adapter ASC assembles into filaments with integral participation of its two Death Domains, PYD and CARD
Reinard Jeffrey T. Nambayan, Suzanne I. Sandin, David A. Quint, David M. Satyadi, Eva de Alba
J Biol Chem. 2019 Jan 11; 294(2): 439–452. Published online 2018 Nov 20. doi: 10.1074/jbc.RA118.004407
PMCID:
PMC6333874
AbstractArticlePDF–5.3M
10.
IN VIVO EVIDENCE OF INFLAMMASOME ACTIVATION DURING SPONTANEOUS LABOR AT TERM
Bogdan Panaitescu, Roberto Romero, Nardhy Gomez-Lopez, Yi Xu, Yaozhu Leng, Eli Maymon, Percy Pacora, Offer Erez, Lami Yeo, Sonia S. Hassan, Chaur-Dong Hsu
J Matern Fetal Neonatal Med. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: J Matern Fetal Neonatal Med. 2019 Jun; 32(12): 1978–1991. Published online 2018 Jan 17. doi: 10.1080/14767058.2017.1422714
PMCID:
PMC6050140
AbstractArticlePDF–503K
11.
ASC contributes to metastasis of oral cavity squamous cell carcinoma
Chi-Sheng Wu, Kai-Ping Chang, Chun-Nan OuYang, Huang-Kai Kao, Chuen Hsueh, Lih-Chyang Chen, Hsiao-Yun Cheng, Ying Liang, Willisa Liou, Chih-lung Liang, Yu-Sun Chang
Oncotarget. 2016 Aug 2; 7(31): 50074–50085. Published online 2016 Jun 29. doi: 10.18632/oncotarget.10317
PMCID:
PMC5226569
AbstractArticlePDF–5.5M
12.
ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication
Masato Kitazawa, Shigeaki Hida, Chifumi Fujii, Shun’ichiro Taniguchi, Kensuke Ito, Tomio Matsumura, Nagisa Okada, Takashi Sakaizawa, Akira Kobayashi, Michiko Takeoka, Shin-ichi Miyagawa
PLoS One. 2017; 12(1): e0169340. Published online 2017 Jan 5. doi: 10.1371/journal.pone.0169340
PMCID:
PMC5215782
AbstractArticlePDF–2.8M
13.
Silencing of ASC in Cutaneous Squamous Cell Carcinoma
Katharina Meier, Stefan K. Drexler, Franziska C. Eberle, Karine Lefort, Amir S. Yazdi
PLoS One. 2016; 11(10): e0164742. Published online 2016 Oct 21. doi: 10.1371/journal.pone.0164742
PMCID:
PMC5074456
AbstractArticlePDF–1.3M
14.
Methylation of Apoptosis-Associated Speck-Like Protein With a Caspase Recruitment Domain and Outcomes in Heart Failure
Brittany Butts, Rebecca A. Gary, Sandra B. Dunbar, Javed Butler
J Card Fail. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: J Card Fail. 2016 May; 22(5): 340–346. Published online 2015 Dec 14. doi: 10.1016/j.cardfail.2015.12.004
PMCID:
PMC4861674
AbstractArticlePDF–339K
15.
A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly
Florian I. Schmidt, Alvin Lu, Jeff W. Chen, Jianbin Ruan, Catherine Tang, Hao Wu, Hidde L. Ploegh
J Exp Med. 2016 May 2; 213(5): 771–790. doi: 10.1084/jem.20151790
PMCID:
PMC4854733
AbstractArticlePDF–3.1M
16.
Epigenetic inactivation of the candidate tumor suppressor gene ASC/TMS1 in human renal cell carcinoma and its role as a potential therapeutic target
Qianling Liu, Jie Jin, Jianming Ying, Yun Cui, Mengkui Sun, Lian Zhang, Yu Fan, Ben Xu, Qian Zhang
Oncotarget. 2015 Sep 8; 6(26): 22706–22723. Published online 2015 Jun 5. doi: 10.18632/oncotarget.4256
PMCID:
PMC4673193
AbstractArticlePDF–4.5M
17.
The CARD plays a critical role in ASC foci formation and inflammasome signaling
Martina Proell, Motti Gerlic, Peter D. Mace, John C. Reed, Stefan J. Riedl
Biochem J. Author manuscript; available in PMC 2014 Mar 26.
Published in final edited form as: Biochem J. 2013 Feb 1; 449(3): 613–621. doi: 10.1042/BJ20121198
PMCID:
PMC3966062
AbstractArticlePDF–3.0M
18.
Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma
Weimin Liu, Yuchun Luo, Jeffrey H. Dunn, David A. Norris, Charles A. Dinarello, Mayumi Fujita
J Invest Dermatol. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: J Invest Dermatol. 2013 Feb; 133(2): 518–527. Published online 2012 Aug 30. doi: 10.1038/jid.2012.317
PMCID:
PMC3511638
AbstractArticlePDF–1.3M
19.
Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells
Melissa J. Parsons, Pritty Patel, Daniel J. Brat, Laronna Colbert, Paula M. Vertino
Cancer Res. Author manuscript; available in PMC 2010 Mar 11.
Published in final edited form as: Cancer Res. 2009 Mar 1; 69(5): 1706–1711. Published online 2009 Feb 17. doi: 10.1158/0008-5472.CAN-08-2351
PMCID:
PMC2837082
AbstractArticlePDF–1.0M
20.
Structure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)
Eva de Alba
J Biol Chem. 2009 Nov 20; 284(47): 32932–32941. Published online 2009 Sep 15. doi: 10.1074/jbc.M109.024273
PMCID:
PMC2781708
AbstractArticlePDF–3.0M

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