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Select item 105486861.

Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning

Alexander Neumann, Olena Ohlei, Fahri Küçükali, Isabelle J. Bos, Jigyasha Timsina, Stephanie Vos, Dmitry Prokopenko, Betty M. Tijms, Ulf Andreasson, Kaj Blennow, Rik Vandenberghe, Philip Scheltens, Charlotte E. Teunissen, Sebastiaan Engelborghs, Giovanni B. Frisoni, Oliver Blin, Jill C. Richardson, Régis Bordet, Alberto Lleó, Daniel Alcolea, Julius Popp, Thomas W. Marsh, Priyanka Gorijala, Christopher Clark, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Richard J. B. Dobson, Cristina Legido-Quigley, Christine Van Broeckhoven, Rudolph E. Tanzi, Mara ten Kate, Christina M. Lill, Frederik Barkhof, Carlos Cruchaga, Simon Lovestone, Johannes Streffer, Henrik Zetterberg, Pieter Jelle Visser, Kristel Sleegers, Lars Bertram, EMIF-AD & ADNI study group

Genome Med. 2023; 15: 79. Published online 2023 Oct 4. doi: 10.1186/s13073-023-01233-z

PMCID:: PMC10548686

Abstract Article PDF–7.0M

Select item 89206572.

MicroRNA-129-1-3p Represses the Progression of Triple-Negative Breast Cancer by Targeting the GRIN2D Gene

Qi Li, Zehui Gu, Qi Tan, Liqun Ren, Suxian Chen

Biomed Res Int. 2022; 2022: 1549357. Published online 2022 Mar 7. doi: 10.1155/2022/1549357

PMCID:: PMC8920657

Abstract Article PDF–1.3M

Select item 65787383.

Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

S Akbarian, NJ Sucher, D Bradley, A Tafazzoli, D Trinh, WP Hetrick, SG Potkin, CA Sandman, WE Bunney, Jr, EG Jones

J Neurosci. 1996 Jan 1; 16(1): 19–30. doi: 10.1523/JNEUROSCI.16-01-00019.1996

PMCID:: PMC6578738

Abstract PDF–3.9M

Select item 49914664.

Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer

Henry J.M. Ferguson, Joseph W. Wragg, Stephen Ward, Victoria L. Heath, Tariq Ismail, Roy Bicknell

Oncotarget. 2016 Apr 12; 7(15): 20440–20454. Published online 2016 Mar 1. doi: 10.18632/oncotarget.7812

PMCID:: PMC4991466

Abstract Article PDF–3.2M

Select item 103802805.

Potential Roles for the GluN2D NMDA Receptor Subunit in Schizophrenia

Chitra Vinnakota, Matthew R. Hudson, Nigel C. Jones, Suresh Sundram, Rachel A. Hill

Int J Mol Sci. 2023 Jul; 24(14): 11835. Published online 2023 Jul 23. doi: 10.3390/ijms241411835

PMCID:: PMC10380280

Abstract Article PDF–793K

Select item 58024966.

Rare loss of function mutations in N-methyl-d-aspartate glutamate receptors and their contributions to schizophrenia susceptibility

Yanjie Yu, Yingni Lin, Yuto Takasaki, Chenyao Wang, Hiroki Kimura, Jingrui Xing, Kanako Ishizuka, Miho Toyama, Itaru Kushima, Daisuke Mori, Yuko Arioka, Yota Uno, Tomoko Shiino, Yukako Nakamura, Takashi Okada, Mako Morikawa, Masashi Ikeda, Nakao Iwata, Yuko Okahisa, Manabu Takaki, Shinji Sakamoto, Toshiyuki Someya, Jun Egawa, Masahide Usami, Masaki Kodaira, Akira Yoshimi, Tomoko Oya-Ito, Branko Aleksic, Kinji Ohno, Norio Ozaki

Transl Psychiatry. 2018; 8: 12. Published online 2018 Jan 10. doi: 10.1038/s41398-017-0061-y

PMCID:: PMC5802496

Abstract Article PDF–694K

Select item 50656527.

GRIN2D Recurrent De Novo Dominant Mutation Causes a Severe Epileptic Encephalopathy Treatable with NMDA Receptor Channel Blockers

Dong Li, Hongjie Yuan, Xilma R. Ortiz-Gonzalez, Eric D. Marsh, Lifeng Tian, Elizabeth M. McCormick, Gabrielle J. Kosobucki, Wenjuan Chen, Anthony J. Schulien, Rosetta Chiavacci, Anel Tankovic, Claudia Naase, Frieder Brueckner, Celina von Stülpnagel-Steinbeis, Chun Hu, Hirofumi Kusumoto, Ulrike B.S. Hedrich, Gina Elsen, Konstanze Hörtnagel, Elias Aizenman, Johannes R. Lemke, Hakon Hakonarson, Stephen F. Traynelis, Marni J. Falk

Am J Hum Genet. 2016 Oct 6; 99(4): 802–816. Published online 2016 Sep 8. doi: 10.1016/j.ajhg.2016.07.013

PMCID:: PMC5065652

Abstract Article PDF–2.9M

Select item 34243198.

Pilot Study of iPS-derived Neural Cells to Examine Biological Effects of Alcohol on Human Neurons in vitro

Richard Lieberman, Eric S. Levine, Henry R. Kranzler, Christine Abreu, Jonathan Covault

Alcohol Clin Exp Res. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Alcohol Clin Exp Res. 2012 Oct; 36(10): 1678–1687. Published online 2012 Apr 6. doi: 10.1111/j.1530-0277.2012.01792.x

PMCID:: PMC3424319

Abstract Article PDF–3.7M

Select item 1215139.

Isolation of Estrogen-Responsive Genes with a CpG Island Library

Toru Watanabe, Satoshi Inoue, Hisahiko Hiroi, Akira Orimo, Hiroyuki Kawashima, Masami Muramatsu

Mol Cell Biol. 1998 Jan; 18(1): 442–449. doi: 10.1128/mcb.18.1.442

PMCID:: PMC121513

Abstract Article PDF–962K

Select item 972262710.

Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs

Tsung-Han Chou, Hyunook Kang, Noriko Simorowski, Stephen F. Traynelis, Hiro Furukawa

Mol Cell. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Mol Cell. 2022 Dec 1; 82(23): 4548–4563.e4. Published online 2022 Oct 28. doi: 10.1016/j.molcel.2022.10.008

PMCID:: PMC9722627

Abstract Article PDF–3.3M

Select item 727202511.

GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons

Jonathan Garst-Orozco, Ruchi Malik, Thomas A. Lanz, Mark L. Weber, Hualin Xi, Dominique Arion, John F. Enwright, III, David A. Lewis, Patricio O’Donnell, Vikaas S. Sohal, Derek L. Buhl

PLoS One. 2020; 15(6): e0233895. Published online 2020 Jun 4. doi: 10.1371/journal.pone.0233895

PMCID:: PMC7272025

Abstract Article PDF–1.6M

Select item 257470112.

Neurotransmission and Bipolar Disorder: A Systematic Family-based Association Study

Jiajun Shi, Judith A. Badner, Eiji Hattori, James B. Potash, Virginia L. Willour, Francis J. McMahon, Elliot S. Gershon, Chunyu Liu

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2008 Nov 5.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 5; 147B(7): 1270–1277. doi: 10.1002/ajmg.b.30769

PMCID:: PMC2574701

Abstract Article PDF–75K

Select item 667169213.

NMDA Receptor Activation by HIV-Tat Protein Is Clade Dependent

Wenxue Li, Yan Huang, Rollie Reid, Joseph Steiner, Tanya Malpica-Llanos, Thomas A. Darden, Susarla K. Shankar, Anita Mahadevan, Parthasarthy Satishchandra, Avindra Nath

J Neurosci. 2008 Nov 19; 28(47): 12190–12198. doi: 10.1523/JNEUROSCI.3019-08.2008

Correction in:: J Neurosci. 2008 Dec 10; 28(50): np.

PMCID:: PMC6671692

Abstract Article PDF–618K

Select item 385507914.

Nedd4 is a Specific E3 Ubiquitin Ligase for the NMDA Receptor Subunit GluN2D

Vivek Gautam, Jonathan C. Trinidad, Ronald A. Rimerman, Blaise M. Costa, Alma L. Burlingame, Daniel T. Monaghan

Neuropharmacology. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Neuropharmacology. 2013 Nov; 74: 10.1016/j.neuropharm.2013.04.035. Published online 2013 Apr 29. doi: 10.1016/j.neuropharm.2013.04.035

PMCID:: PMC3855079

Abstract Article PDF–3.5M

Select item 489614715.

Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine

Wesley N. Wayman, Lihua Chen, Amanda L. Persons, T. Celeste Napier

Curr HIV Res. Author manuscript; available in PMC 2016 Jun 7.

Published in final edited form as: Curr HIV Res. 2015; 13(1): 80–87. doi: 10.2174/0929867322666150311164504

PMCID:: PMC4896147

Abstract Article PDF–361K

Select item 330947016.

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia

J Tarabeux, O Kebir, J Gauthier, F F Hamdan, L Xiong, A Piton, D Spiegelman, É Henrion, B Millet, S2D team, F Fathalli, R Joober, J L Rapoport, L E DeLisi, É Fombonne, L Mottron, N Forget-Dubois, M Boivin, J L Michaud, P Drapeau, R G Lafrenière, G A Rouleau, M-O Krebs

Transl Psychiatry. 2011 Nov; 1(11): e55. Published online 2011 Nov 15. doi: 10.1038/tp.2011.52

PMCID:: PMC3309470

Abstract Article PDF–299K

Select item 362218817.

Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures

Angela H. Shin, Stanley A. Thayer

Mol Cell Neurosci. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Mol Cell Neurosci. 2013 May; 54: 22–29. Published online 2012 Dec 23. doi: 10.1016/j.mcn.2012.12.005

PMCID:: PMC3622188

Abstract Article PDF–1.7M

Select item 355633918.

HIV Immune Complexes Prevent Excitotoxicity by Interaction with NMDA Receptors

Jeffrey A. Rumbaugh, Muznabanu Bachani, Wenxue Li, Tracy R. Butler, Katherine J. Smith, Mario A. Bianchet, Tongguang Wang, Mark A. Prendergast, Ned Sacktor, Avindra Nath

Neurobiol Dis. Author manuscript; available in PMC 2014 Feb 25.

Published in final edited form as: Neurobiol Dis. 2013 Jan; 0: 169–176. Published online 2012 Aug 25. doi: 10.1016/j.nbd.2012.08.013

PMCID:: PMC3556339

Abstract Article PDF–749K

Select item 267867919.

Human Immunodeficiency Virus Protein Tat Induces Synapse Loss via a Reversible Process That Is Distinct from Cell Death

Hee Jung Kim, Kirill A. Martemyanov, Stanley A. Thayer

J Neurosci. 2008 Nov 26; 28(48): 12604–12613. doi: 10.1523/JNEUROSCI.2958-08.2008

PMCID:: PMC2678679

Abstract Article PDF–553K

Select item 180560720.

HIV-tat induces formation of an LRP–PSD-95– NMDAR–nNOS complex that promotes apoptosis in neurons and astrocytes

Eliseo A. Eugenin, Jessie E. King, Avindra Nath, Tina M. Calderon, R. Suzanne Zukin, Michael V. L. Bennett, Joan W. Berman

Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9): 3438–3443. Published online 2007 Feb 21. doi: 10.1073/pnas.0611699104

PMCID:: PMC1805607

Abstract Article PDF–1.2M

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