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Items: 1 to 20 of 106

1.
HIPK2 in the physiology of nervous system and its implications in neurological disorders
F. Sardina, A. Conte, S. Paladino, G.M. Pierantoni, C. Rinaldo
Biochim Biophys Acta Mol Cell Res. 2023 Jun; 1870(5): 119465. doi: 10.1016/j.bbamcr.2023.119465
PMCID:
PMC10236203
AbstractArticle
2.
Exercise and cardioprotection: A “HIP” side of HIPK2 in the heart
Arintaya Phrommintikul, Siriporn C Chattipakorn, Nipon Chattipakorn
EBioMedicine. 2022 Jan; 75: 103766. Published online 2021 Dec 17. doi: 10.1016/j.ebiom.2021.103766
PMCID:
PMC8693282
ArticlePDF–100K
3.
An Alternative Splice Variant of HIPK2 with Intron Retention Contributes to Cytokinesis
Veronica Gatti, Manuela Ferrara, Ilaria Virdia, Silvia Matteoni, Laura Monteonofrio, Simona di Martino, Maria Grazia Diodoro, Giuliana Di Rocco, Cinzia Rinaldo, Silvia Soddu
Cells. 2020 Feb; 9(2): 484. Published online 2020 Feb 20. doi: 10.3390/cells9020484
PMCID:
PMC7072727
AbstractArticlePDF–3.4M
4.
Impact of genetic variant of HIPK2 on the risk of severe radiation pneumonitis in lung cancer patients treated with radiation therapy
Yang Tang, Li Yang, Wan Qin, Min’ Xiao Yi, Bo Liu, Xiang’Lin Yuan
Radiat Oncol. 2020; 15: 9. Published online 2020 Jan 8. doi: 10.1186/s13014-019-1456-0
PMCID:
PMC6950809
AbstractArticlePDF–689K
5.
HIPK2 role in the tumor–host interaction: Impact on fibroblasts transdifferentiation CAF‐like
Alessia Garufi, Gianandrea Traversi, Mara Cirone, Gabriella D'Orazi
IUBMB Life. 2019 Dec; 71(12): 2055–2061. Published online 2019 Aug 15. doi: 10.1002/iub.2144
PMCID:
PMC6899452
AbstractArticlePDF–2.0M
6.
Homeodomain‐interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer
Yi Qin, Qiangsheng Hu, Shunrong Ji, Jin Xu, Weixing Dai, Wensheng Liu, Wenyan Xu, Qiqing Sun, Zheng Zhang, Quanxing Ni, Xianjun Yu, Bo Zhang, Xiaowu Xu
Cell Prolif. 2019 May; 52(3): e12603. Published online 2019 Apr 1. doi: 10.1111/cpr.12603
PMCID:
PMC6536454
AbstractArticlePDF–1.9M
7.
HIPK2 is involved in cell proliferation and its suppression promotes growth arrest independently of DNA damage
S. Iacovelli, L. Ciuffini, C. Lazzari, G. Bracaglia, C. Rinaldo, A. Prodosmo, A. Bartolazzi, A. Sacchi, S. Soddu
Cell Prolif. 2009 Jun; 42(3): 373–384. Published online 2009 Mar 31. doi: 10.1111/j.1365-2184.2009.00601.x
PMCID:
PMC6496359
AbstractArticlePDF–516K
8.
HIPK2 and extrachromosomal histone H2B are separately recruited by Aurora-B for cytokinesis
Laura Monteonofrio, Davide Valente, Manuela Ferrara, Serena Camerini, Roberta Miscione, Marco Crescenzi, Cinzia Rinaldo, Silvia Soddu
Oncogene. 2018; 37(26): 3562–3574. Published online 2018 Mar 22. doi: 10.1038/s41388-018-0191-6
PMCID:
PMC6021368
AbstractArticlePDF–2.2M
9.
HIPK2 Overexpression and Its Prognostic Role in Human Papillomavirus-Positive Tonsillar Squamous Cell Carcinoma
Mi Jung Kwon, So Young Kang, Eun Sook Nam, Seong Jin Cho, Young-Soo Rho
Biomed Res Int. 2017; 2017: 1056427. Published online 2017 May 21. doi: 10.1155/2017/1056427
PMCID:
PMC5457774
AbstractArticlePDF–1.9M
10.
Apoptosis induced by a HIPK2 full-length-specific siRNA is due to off-target effects rather than prevalence of HIPK2-Δe8 isoform
Giuliana Di Rocco, Alessandra Verdina, Veronica Gatti, Ilaria Virdia, Gabriele Toietta, Matilde Todaro, Giorgio Stassi, Silvia Soddu
Oncotarget. 2016 Jan 12; 7(2): 1675–1686. Published online 2015 Nov 28. doi: 10.18632/oncotarget.6423
PMCID:
PMC4811489
AbstractArticlePDF–4.5M
11.
Glucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapy
A Garufi, A Ricci, D Trisciuoglio, E Iorio, G Carpinelli, G Pistritto, M Cirone, G D′Orazi
Cell Death Dis. 2013 May; 4(5): e639. Published online 2013 May 23. doi: 10.1038/cddis.2013.163
PMCID:
PMC3674370
AbstractArticlePDF–1.1M
12.
Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress
Kiros Hailemariam, Kenta Iwasaki, Bo-Wen Huang, Kensuke Sakamoto, Yoshiaki Tsuji
J Cell Sci. 2010 Nov 15; 123(22): 3863–3871. Published online 2010 Oct 27. doi: 10.1242/jcs.073627
PMCID:
PMC2972272
AbstractArticle
13.
miR-4653-3p overexpression is associated with a poor prognosis of pancreatic ductal adenocarcinoma via HIPK2 downregulation
Kenichi Hirabayashi, Masaki Miyazawa, Yumi Takanashi, Masashi Morimachi, Aya Kawanishi, Tsubasa Saika, Toshio Nakagohri, Naoya Nakamura
Sci Rep. 2022; 12: 17927. Published online 2022 Oct 26. doi: 10.1038/s41598-022-22950-2
PMCID:
PMC9606280
AbstractArticlePDF–2.4M
14.
Exosomal miR-1260b derived from non-small cell lung cancer promotes tumor metastasis through the inhibition of HIPK2
Dong Ha Kim, Hyojeong Park, Yun Jung Choi, Myoung-Hee Kang, Tae-Keun Kim, Chan-Gi Pack, Chang-Min Choi, Jae Cheol Lee, Jin Kyung Rho
Cell Death Dis. 2021 Aug; 12(8): 747. Published online 2021 Jul 28. doi: 10.1038/s41419-021-04024-9
PMCID:
PMC8319168
AbstractArticlePDF–4.0M
15.
HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission
Alessandra Pisciottani, Loredana Biancolillo, Manuela Ferrara, Davide Valente, Francesca Sardina, Laura Monteonofrio, Serena Camerini, Marco Crescenzi, Silvia Soddu, Cinzia Rinaldo
Cells. 2019 Jul; 8(7): 684. Published online 2019 Jul 5. doi: 10.3390/cells8070684
PMCID:
PMC6678495
AbstractArticlePDF–2.2M
16.
p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function
Jong-Ryoul Choi, Seo-Young Lee, Ki Soon Shin, Cheol Yong Choi, Shin Jung Kang
Sci Rep. 2017; 7: 16136. Published online 2017 Nov 23. doi: 10.1038/s41598-017-16489-w
PMCID:
PMC5701035
AbstractArticlePDF–2.9M
17.
HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation
Alessandra Verdina, Giuliana Di Rocco, Ilaria Virdia, Laura Monteonofrio, Veronica Gatti, Eleonora Policicchio, Alessandro Bruselles, Marco Tartaglia, Silvia Soddu
Oncotarget. 2017 Mar 7; 8(10): 16744–16754. Published online 2017 Jan 2. doi: 10.18632/oncotarget.14421
PMCID:
PMC5369998
AbstractArticlePDF–2.7M
18.
Arsenic-induced Activation of the Homeodomain Interacting Protein Kinase 2 (HIPK2) to cAMP-response element binding protein (CREB) Axis
Kazunori Hashimoto, Yoshiaki Tsuji
J Mol Biol. Author manuscript; available in PMC 2018 Jan 6.
Published in final edited form as: J Mol Biol. 2017 Jan 6; 429(1): 64–78. Published online 2016 Nov 21. doi: 10.1016/j.jmb.2016.11.015
PMCID:
PMC5186405
AbstractArticlePDF–1.1M
19.
Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype
S Anzilotti, M Tornincasa, R Gerlini, A Conte, P Brancaccio, O Cuomo, G Bianco, A Fusco, L Annunziato, G Pignataro, G M Pierantoni
Cell Death Dis. 2015 Dec; 6(12): e2004. Published online 2015 Dec 3. doi: 10.1038/cddis.2015.298
PMCID:
PMC4720876
AbstractArticlePDF–4.7M
20.
The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage
Nina Reuven, Julia Adler, Ziv Porat, Tilman Polonio-Vallon, Thomas G. Hofmann, Yosef Shaul
J Biol Chem. 2015 Jul 3; 290(27): 16478–16488. Published online 2015 May 5. doi: 10.1074/jbc.M114.628982
PMCID:
PMC4505402
AbstractArticlePDF–1.0M

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