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Items: 1 to 20 of 57

1.
Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein: Fatty Acid Binding Revisited
Jun Cai, Christian Lücke, Zhongjing Chen, Ye Qiao, Elena Klimtchuk, James A. Hamilton
Biophys J. 2012 Jun 6; 102(11): 2585–2594. doi: 10.1016/j.bpj.2012.04.039
PMCID:
PMC3368126
ArticlePDF–936K
2.
Three-dimensional structure of a pyridoxal-phosphate-dependent enzyme, mitochondrial aspartate aminotransferase.
G C Ford, G Eichele, J N Jansonius
Proc Natl Acad Sci U S A. 1980 May; 77(5): 2559–2563. doi: 10.1073/pnas.77.5.2559
PMCID:
PMC349441
SummaryPage BrowsePDF–1.0M
3.
Circular RNA circ_0003028 contributes to tumorigenesis by regulating GOT2 via miR-1298-5p in non-small cell lung cancer
Hongjun Guan, Changpeng Sun, Yinfeng Gu, Jinjin Li, Jie Ji, Yongxian Zhu
Bioengineered. 2021; 12(1): 2326–2340. Published online 2021 Jun 2. doi: 10.1080/21655979.2021.1935064
PMCID:
PMC8806680
ArticlePDF–4.2M
4.
High circ-SEC31A expression predicts unfavorable prognoses in non-small cell lung cancer by regulating the miR-520a-5p/GOT-2 axis
Mingming Jin, Chunzi Shi, Qian Hua, Tian Li, Chen Yang, Yue Wu, Licong Zhao, Hao Yang, Jiaqi Zhang, Cheng Hu, Gang Huang
Aging (Albany NY) 2020 Jun 15; 12(11): 10381–10397. Published online 2020 Jun 4. doi: 10.18632/aging.103264
PMCID:
PMC7346017
ArticlePDF–2.1M
5.
SIRT3-dependent GOT2 acetylation status affects the malate–aspartate NADH shuttle activity and pancreatic tumor growth
Hui Yang, Lisha Zhou, Qian Shi, Yuzheng Zhao, Huaipeng Lin, Mengli Zhang, Shimin Zhao, Yi Yang, Zhi-Qiang Ling, Kun-Liang Guan, Yue Xiong, Dan Ye
EMBO J. 2015 Apr 15; 34(8): 1110–1125. Published online 2015 Mar 9. doi: 10.15252/embj.201591041
PMCID:
PMC4406655
ArticlePDF–1.4M
6.
Bi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy
Clara D.M. van Karnebeek, Rúben J. Ramos, Xiao-Yan Wen, Maja Tarailo-Graovac, Joseph G. Gleeson, Cristina Skrypnyk, Koroboshka Brand-Arzamendi, Farhad Karbassi, Mahmoud Y. Issa, Robin van der Lee, Britt I. Drögemöller, Janet Koster, Justine Rousseau, Philippe M. Campeau, Youdong Wang, Feng Cao, Meng Li, Jos Ruiter, Jolita Ciapaite, Leo A.J. Kluijtmans, Michel A.A.P. Willemsen, Judith J. Jans, Colin J. Ross, Liesbeth T. Wintjes, Richard J. Rodenburg, Marleen C.D.G. Huigen, Zhengping Jia, Hans R. Waterham, Wyeth W. Wasserman, Ronald J.A. Wanders, Nanda M. Verhoeven-Duif, Maha S. Zaki, Ron A. Wevers
Am J Hum Genet. 2019 Sep 5; 105(3): 534–548. Published online 2019 Aug 15. doi: 10.1016/j.ajhg.2019.07.015
PMCID:
PMC6732527
ArticlePDF–2.3M
7.
Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation
Ruoxi Hong, Weimin Zhang, Xi Xia, Kai Zhang, Yan Wang, Mengjiao Wu, Jiawen Fan, Jinting Li, Wen Xia, Fei Xu, Jie Chen, Shusen Wang, Qimin Zhan
Mol Oncol. 2019 Apr; 13(4): 959–977. Published online 2019 Mar 1. doi: 10.1002/1878-0261.12466
Correction in:
Mol Oncol. 2020 Oct; 14(10): 2696.
PMCID:
PMC6441895
ArticlePDF–2.6M
8.
Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression
Maren Feist, Philipp Schwarzfischer, Paul Heinrich, Xueni Sun, Judith Kemper, Frederike von Bonin, Paula Perez-Rubio, Franziska Taruttis, Thorsten Rehberg, Katja Dettmer, Wolfram Gronwald, Jörg Reinders, Julia C. Engelmann, Jan Dudek, Wolfram Klapper, Lorenz Trümper, Rainer Spang, Peter J. Oefner, Dieter Kube
Nat Commun. 2018; 9: 1514. Published online 2018 Apr 17. doi: 10.1038/s41467-018-03803-x
PMCID:
PMC5904148
ArticlePDF–1.6M
9.
Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria
Travis J. Riedel, Lynnette C. Johnson, John Knight, Roy R. Hantgan, Ross P. Holmes, W. Todd Lowther
PLoS One. 2011; 6(10): e26021. Published online 2011 Oct 6. doi: 10.1371/journal.pone.0026021
PMCID:
PMC3188589
ArticlePDF–991K
10.
Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study
Nathan E Wineinger, Amit Patki, Kristin J Meyers, Ulrich Broeckel, Charles C Gu, DC Rao, Richard B Devereux, Donna K Arnett, Hemant K Tiwari
BMC Med Genomics. 2011; 4: 4. Published online 2011 Jan 11. doi: 10.1186/1755-8794-4-4
PMCID:
PMC3027088
ArticlePDF–2.0M
11.
Common variants at ten loci influence myocardial repolarization: the QTGEN consortium
Christopher Newton-Cheh, Mark Eijgelsheim, Kenneth Rice, Paul I. W. de Bakker, Xiaoyan Yin, Karol Estrada, Joshua Bis, Kristin Marciante, Fernando Rivadeneira, Peter A. Noseworthy, Nona Sotoodehnia, Nicholas L. Smith, Jerome I. Rotter, Jan A. Kors, Jacqueline C.M. Witteman, Albert Hofman, Susan R. Heckbert, Christopher J. O’Donnell, Andre G. Uitterlinden, Bruce M. Psaty, Thomas Lumley, Martin G. Larson, Bruno H.Ch. Stricker
Nat Genet. Author manuscript; available in PMC 2009 Oct 1.
Published in final edited form as: Nat Genet. 2009 Apr; 41(4): 399–406. Published online 2009 Mar 22. doi: 10.1038/ng.364
PMCID:
PMC2701449
ArticlePDF–804K
12.
TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics
Stephani A. Davis, Sheed Itaman, Christopher M. Khalid-Janney, Justin A. Sherard, James A. Dowell, Nigel J. Cairns, Michael A. Gitcho
Neurosci Lett. Author manuscript; available in PMC 2019 Jun 21.
Published in final edited form as: Neurosci Lett. 2018 Jun 21; 678: 8–15. Published online 2018 Apr 30. doi: 10.1016/j.neulet.2018.04.053
PMCID:
PMC5975202
ArticlePDF–543K
13.
An Interaction Network of the Human SEPT9 Established by Quantitative Mass Spectrometry
Matthias Hecht, Reinhild Rösler, Sebastian Wiese, Nils Johnsson, Thomas Gronemeyer
G3 (Bethesda) 2019 Jun; 9(6): 1869–1880. Published online 2019 Apr 11. doi: 10.1534/g3.119.400197
PMCID:
PMC6553528
ArticlePDF–2.9M
14.
Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia
Carmela Ciardullo, Katarzyna Szoltysek, Peixun Zhou, Monika Pietrowska, Lukasz Marczak, Elaine Willmore, Amir Enshaei, Anna Walaszczyk, Jia Yee Ho, Vikki Rand, Scott Marshall, Andrew G. Hall, Christine J. Harrison, Meera Soundararajan, Jeyanthy Eswaran
Cancers (Basel) 2022 Jan; 14(1): 23. Published online 2021 Dec 21. doi: 10.3390/cancers14010023
PMCID:
PMC8750551
ArticlePDF–2.8M
15.
USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c
Ye Yao, Weijie Ma, Yonghua Guo, Yingyi Liu, Peng Xia, Xiaoling Wu, Yiran Chen, Kunlei Wang, Chengjie Mei, Ganggang Wang, Xiaomian Li, Zhonglin Zhang, Xi Chen, Yufeng Yuan
Oncogenesis. 2022 Dec; 11(1): 31. Published online 2022 Jun 2. doi: 10.1038/s41389-022-00404-8
Correction in:
Oncogenesis. 2023 Dec; 12(1): 27.
PMCID:
PMC9163188
ArticlePDF–8.2M
16.
Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action
Johannes Gubat, Karthik Selvaraju, Linda Sjöstrand, Dhananjay Kumar Singh, Maria V. Turkina, Bernhard Schmierer, Pierre Sabatier, Roman A. Zubarev, Stig Linder, Pádraig D’Arcy
Front Oncol. 2022; 12: 852980. Published online 2022 Apr 22. doi: 10.3389/fonc.2022.852980
PMCID:
PMC9076133
ArticlePDF–6.6M
17.
Sequential Use of Transcriptional Profiling, Expression Quantitative Trait Mapping, and Gene Association Implicates MMP20 in Human Kidney Aging
Heather E. Wheeler, E. Jeffrey Metter, Toshiko Tanaka, Devin Absher, John Higgins, Jacob M. Zahn, Julie Wilhelmy, Ronald W. Davis, Andrew Singleton, Richard M. Myers, Luigi Ferrucci, Stuart K. Kim
PLoS Genet. 2009 Oct; 5(10): e1000685. Published online 2009 Oct 16. doi: 10.1371/journal.pgen.1000685
PMCID:
PMC2752811
ArticlePDF–409K
18.
Phosphoproteome Analysis of Functional Mitochondria Isolated from Resting Human Muscle Reveals Extensive Phosphorylation of Inner Membrane Protein Complexes and Enzymes
Xiaolu Zhao, Ileana R. León, Steffen Bak, Martin Mogensen, Krzysztof Wrzesinski, Kurt Højlund, Ole Nørregaard Jensen
Mol Cell Proteomics. 2011 Jan; 10(1): M110.000299. Published online 2010 Sep 10. doi: 10.1074/mcp.M110.000299
PMCID:
PMC3013442
ArticlePDF–310K
19.
An atlas of genetic influences on human blood metabolites
So-Youn Shin, Eric B. Fauman, Ann-Kristin Petersen, Jan Krumsiek, Rita Santos, Jie Huang, Matthias Arnold, Idil Erte, Vincenzo Forgetta, Tsun-Po Yang, Klaudia Walter, Cristina Menni, Lu Chen, Louella Vasquez, Ana M. Valdes, Craig L. Hyde, Vicky Wang, Daniel Ziemek, Phoebe Roberts, Li Xi, Elin Grundberg, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Melanie Waldenberger, J. Brent Richards, Robert P. Mohney, Michael V. Milburn, Sally L. John, Jeff Trimmer, Fabian J. Theis, John P. Overington, Karsten Suhre, M. Julia Brosnan, Christian Gieger, Gabi Kastenmüller, Tim D Spector, Nicole Soranzo
Nat Genet. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 543–550. Published online 2014 May 11. doi: 10.1038/ng.2982
PMCID:
PMC4064254
ArticlePDF–2.4M
20.
IKK-mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5
Jingzi Zhang, Ruoyu Zhao, Christine L. N. Bryant, Kenneth Wu, Zhihong Liu, Yibing Ding, Yue Zhao, Bin Xue, Zhen-Qiang Pan, Chaojun Li, Lan Huang, Lei Fang
J Proteome Res. Author manuscript; available in PMC 2020 Jun 17.
Published in final edited form as: J Proteome Res. 2020 Mar 6; 19(3): 1119–1130. Published online 2020 Feb 3. doi: 10.1021/acs.jproteome.9b00626
PMCID:
PMC7299130
ArticlePDF–2.2M

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