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Select item 92152281.

G Protein Subunit β1 Facilitates Influenza A Virus Replication by Promoting the Nuclear Import of PB2

Huabin Zheng, Liping Ma, Rui Gui, Xian Lin, Xianliang Ke, Xiaoqin Jian, Chang Ye, Quanjiao Chen

J Virol. 2022 Jun; 96(12): e00494-22. Published online 2022 May 23. doi: 10.1128/jvi.00494-22

Correction in:: J Virol. 2023 Jun; 97(6): e00546-23.

PMCID:: PMC9215228

Abstract Article PDF–5.5M

Select item 56663222.

An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia

O Zimmermannova, E Doktorova, J Stuchly, V Kanderova, D Kuzilkova, H Strnad, J Starkova, M Alberich-Jorda, J H F Falkenburg, J Trka, J Petrak, J Zuna, M Zaliova

Oncogene. 2017 Oct 26; 36(43): 5985–5994. Published online 2017 Jun 26. doi: 10.1038/onc.2017.210

PMCID:: PMC5666322

Abstract Article PDF–2.0M

Select item 48635623.

Germline De Novo Mutations in GNB1 Cause Severe Neurodevelopmental Disability, Hypotonia, and Seizures

Slavé Petrovski, Sébastien Küry, Candace T. Myers, Kwame Anyane-Yeboa, Benjamin Cogné, Martin Bialer, Fan Xia, Parisa Hemati, James Riviello, Michele Mehaffey, Thomas Besnard, Emily Becraft, Alexandrea Wadley, Anya Revah Politi, Sophie Colombo, Xiaolin Zhu, Zhong Ren, Ian Andrews, Tracy Dudding-Byth, Amy L. Schneider, Geoffrey Wallace, University of Washington Center for Mendelian Genomics, Aaron B.I. Rosen, Susan Schelley, Gregory M. Enns, Pierre Corre, Joline Dalton, Sandra Mercier, Xénia Latypova, Sébastien Schmitt, Edwin Guzman, Christine Moore, Louise Bier, Erin L. Heinzen, Peter Karachunski, Natasha Shur, Theresa Grebe, Alice Basinger, Joanne M. Nguyen, Stéphane Bézieau, Klaas Wierenga, Jonathan A. Bernstein, Ingrid E. Scheffer, Jill A. Rosenfeld, Heather C. Mefford, Bertrand Isidor, David B. Goldstein

Am J Hum Genet. 2016 May 5; 98(5): 1001–1010. Published online 2016 Apr 21. doi: 10.1016/j.ajhg.2016.03.011

PMCID:: PMC4863562

Abstract Article PDF–530K

Select item 37434584.

Selection of Phototransduction Genes in Homo sapiens

Mark Christopher, Todd E. Scheetz, Robert F. Mullins, Michael D. Abràmoff

Invest Ophthalmol Vis Sci. 2013 Aug; 54(8): 5489–5496. Published online 2013 Aug 13. doi: 10.1167/iovs.12-11454

PMCID:: PMC3743458

Abstract Article PDF–561K

Select item 35366925.

Association of genetic variations in GNB1 with response to peginterferon plus ribavirin therapy for chronic hepatitis C in a Chinese population in Taiwan

Yun-Ping Lim, Fuu-Jen Tsai, Wen-Ling Liao, Ni Tien, Dong-Zong Hung, Cheng-Yuan Peng, Lei Wan

BMC Gastroenterol. 2012; 12: 167. Published online 2012 Nov 22. doi: 10.1186/1471-230X-12-167

PMCID:: PMC3536692

Abstract Article PDF–883K

Select item 89739376.

Shikonin induces cell autophagy via modulating the microRNA -545-3p/guanine nucleotide binding protein beta polypeptide 1 axis, thereby disrupting cellular carcinogenesis in colon cancer

ZhiWei Hu, XinDong Zhou, DeQiang Zeng, JiaJun Lai

Bioengineered. 2022; 13(3): 5928–5941. Published online 2022 Feb 22. doi: 10.1080/21655979.2021.2024638

PMCID:: PMC8973937

Abstract Article PDF–2.7M

Select item 60755437.

Novel GNB1 mutations disrupt assembly and function of G protein heterotrimers and cause global developmental delay in humans

Katja Lohmann, Ikuo Masuho, Dipak N. Patil, Hauke Baumann, Eva Hebert, Sofia Steinrücke, Daniel Trujillano, Nickolas K. Skamangas, Valerija Dobricic, Irina Hüning, Gabriele Gillessen-Kaesbach, Ana Westenberger, Dusanka Savic-Pavicevic, Alexander Münchau, Gabriela Oprea, Christine Klein, Arndt Rolfs, Kirill A. Martemyanov

Hum Mol Genet. 2017 Mar 15; 26(6): 1078–1086. Published online 2017 Jan 13. doi: 10.1093/hmg/ddx018

PMCID:: PMC6075543

Abstract Article PDF–781K

Select item 26334828.

Association of the Asn306Ser variant of the SP4 transcription factor and an intronic variant in the β-subunit of transducin with digenic disease

Yong-Qing Gao, Michael Danciger, Riza Köksal Özgül, Yekaterina E. Gribanova, Samuel G. Jacobson, Debora B. Farber

Mol Vis. 2007; 13: 287–292. Published online 2007 Feb 28.

PMCID:: PMC2633482

Abstract Article PDF–283K

Select item 21736279.

The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gβγ

Elsa-Noah N'Diaye, Eric J. Brown

J Cell Biol. 2003 Dec 8; 163(5): 1157–1165. doi: 10.1083/jcb.200307155

PMCID:: PMC2173627

Abstract Article PDF–321K

Select item 897416410.

AFAP1 antisense RNA 1 promotes retinoblastoma progression by sponging microRNA miR-545-3p that targets G protein subunit beta 1

Wenting Tang, Li Zhang, Jing Li, Yu Guan

Bioengineered. 2022; 13(3): 5638–5652. Published online 2022 Feb 22. doi: 10.1080/21655979.2022.2033464

PMCID:: PMC8974164

Abstract Article PDF–3.8M

Select item 821530011.

Gβγ translocation to the Golgi apparatus activates ARF1 to spatiotemporally regulate G protein–coupled receptor signaling to MAPK

Mostafa Khater, Christian N. Bryant, Guangyu Wu

J Biol Chem. 2021 Jan-Jun; 296: 100805. Published online 2021 May 19. doi: 10.1016/j.jbc.2021.100805

PMCID:: PMC8215300

Abstract Article PDF–3.4M

Select item 741566312.

Structure of a D₂ dopamine receptor-G protein complex in a lipid membrane

Jie Yin, Kuang-Yui M. Chen, Mary J. Clark, Mahdi Hijazi, Punita Kumari, Xiao-chen Bai, Roger K. Sunahara, Patrick Barth, Daniel M. Rosenbaum

Nature. Author manuscript; available in PMC 2020 Dec 11.

Published in final edited form as: Nature. 2020 Aug; 584(7819): 125–129. Published online 2020 Jun 11. doi: 10.1038/s41586-020-2379-5

PMCID:: PMC7415663

Abstract Article PDF–6.3M

Select item 583244113.

Phase-plate cryo-EM structure of a class B GPCR-G protein complex

Yi-Lynn Liang, Maryam Khoshouei, Mazdak Radjainia, Yan Zhang, Alisa Glukhova, Jeffrey Tarrasch, David M Thal, Sebastian G. B. Furness, George Christopoulos, Thomas Coudrat, Radostin Danev, Wolfgang Baumeister, Laurence J. Miller, Arthur Christopoulos, Brian K Kobilka, Denise Wootten, Georgios Skiniotis, Patrick M. Sexton

Nature. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: Nature. 2017 Jun 1; 546(7656): 118–123. Published online 2017 Apr 24. doi: 10.1038/nature22327

PMCID:: PMC5832441

Abstract Article PDF–2.4M

Select item 512278814.

Four-and-a-half LIM Domains 1 (FHL1) Protein Interacts with the Rho Guanine Nucleotide Exchange Factor PLEKHG2/FLJ00018 and Regulates Cell Morphogenesis

Katsuya Sato, Masashi Kimura, Kazue Sugiyama, Masashi Nishikawa, Yukio Okano, Hitoshi Nagaoka, Takahiro Nagase, Yukio Kitade, Hiroshi Ueda

J Biol Chem. 2016 Nov 25; 291(48): 25227–25238. Published online 2016 Oct 20. doi: 10.1074/jbc.M116.759571

PMCID:: PMC5122788

Abstract Article PDF–2.4M

Select item 465462815.

X-ray structure of the mammalian GIRK2 – ß? G protein complex

Matthew R. Whorton, Roderick MacKinnon

Nature. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Nature. 2013 Jun 13; 498(7453): 190–197. Published online 2013 Jun 5. doi: 10.1038/nature12241

PMCID:: PMC4654628

Abstract Article PDF–2.1M

Select item 428911516.

Mutations in G protein beta subunits promote transformation and kinase inhibitor resistance

Akinori Yoda, Guillaume Adelmant, Jerome Tamburini, Bjoern Chapuy, Nobuaki Shindoh, Yuka Yoda, Oliver Weigert, Nadja Kopp, Shuo-Chieh Wu, Sunhee S. Kim, Huiyun Liu, Trevor Tivey, Amanda L. Christie, Kutlu G. Elpek, Joseph Card, Kira Gritsman, Jason Gotlib, Michael W. Deininger, Hideki Makishima, Shannon J. Turley, Nathalie Javidi-Sharifi, Jaroslaw P. Maciejewski, Siddhartha Jaiswal, Benjamin L. Ebert, Scott J. Rodig, Jeffrey W. Tyner, Jarrod A. Marto, David M. Weinstock, Andrew A. Lane

Nat Med. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Nat Med. 2015 Jan; 21(1): 71–75. Published online 2014 Dec 8. doi: 10.1038/nm.3751