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Select item 58283821.

Genetic studies of human neuropathic pain conditions: a review

Katerina Zorina-Lichtenwalter, Marc Parisien, Luda Diatchenko

Pain. 2018 Mar; 159(3): 583–594. Published online 2017 Nov 3. doi: 10.1097/j.pain.0000000000001099

PMCID:: PMC5828382

Abstract Article PDF–569K

Select item 27387872.

Lentivirus mediated shRNA interference targeting MAT2B induces growth-inhibition and apoptosis in hepatocellular carcinoma

Qun Wang, Quan-Yan Liu, Zhi-Su Liu, Qun Qian, Quan Sun, Ding-Yu Pan

World J Gastroenterol. 2008 Aug 7; 14(29): 4633–4642. Published online 2008 Aug 7. doi: 10.3748/wjg.14.4633

PMCID:: PMC2738787

Abstract Article PDF–1.1M

Select item 25765263.

Selective Targeting of Leukemic Cell Growth in Vivo and in Vitro Using a Gene Silencing Approach to Diminish S-Adenosylmethionine Synthesis

Ramy R. Attia, Lidia A. Gardner, Engy Mahrous, Debra J. Taxman, Leighton LeGros, Sarah Rowe, Jenny P.-Y. Ting, Arthur Geller, Malak Kotb

J Biol Chem. 2008 Nov 7; 283(45): 30788–30795. doi: 10.1074/jbc.M804159200

PMCID:: PMC2576526

Abstract Article PDF–586K

Select item 24091104.

Expression Pattern, Regulation, and Functions of Methionine Adenosyltransferase 2β Splicing Variants in Hepatoma Cells

HEPING YANG, AINHOA IGLESIAS ARA, NATHANIEL MAGILNICK, MENG XIA, KOMAL RAMANI, HUI CHEN, TAUNIA D. LEE, JOSÉ M. MATO, SHELLY C. LU

Gastroenterology. Author manuscript; available in PMC 2008 Jun 3.

Published in final edited form as: Gastroenterology. 2008 Jan; 134(1): 281–291. Published online 2007 Oct 18. doi: 10.1053/j.gastro.2007.10.027

PMCID:: PMC2409110

Abstract Article PDF–1.9M

Select item 86382595.

Human Mat2A Uses an Ordered Kinetic Mechanism and Is Stabilized but Not Regulated by Mat2B

Jonathan Bailey, Holly Douglas, Laura Masino, Luiz Pedro Sorio de Carvalho, Argyrides Argyrou

Biochemistry. 2021 Nov 30; 60(47): 3621–3632. Published online 2021 Nov 15. doi: 10.1021/acs.biochem.1c00672

PMCID:: PMC8638259

Abstract Article PDF–3.8M

Select item 68500146.

Control and regulation of S‐Adenosylmethionine biosynthesis by the regulatory β subunit and quinolone‐based compounds

Jiraporn Panmanee, Jack Bradley‐Clarke, Jose M. Mato, Paul M. O'Neill, Svetlana V. Antonyuk, S. Samar Hasnain

FEBS J. 2019 Jun; 286(11): 2135–2154. Published online 2019 Mar 4. doi: 10.1111/febs.14790

PMCID:: PMC6850014

Abstract Article PDF–5.7M

Select item 48392867.

ROLE OF METHIONINE ADENOSYLTRANSFERASE α2 AND β PHOSPHORYLATION AND STABILIZATION IN HUMAN HEPATIC STELLATE CELL TRANS-DIFFERENTIATION

Komal Ramani, Shant Donoyan, Maria Lauda Tomasi, Sunhee Park

J Cell Physiol. Author manuscript; available in PMC 2016 Apr 21.

Published in final edited form as: J Cell Physiol. 2015 May; 230(5): 1075–1085. doi: 10.1002/jcp.24839

PMCID:: PMC4839286

Abstract Article PDF–1.5M

Select item 43808428.

Methionine Adenosyltransferase 2B–GIT1 Complex Serves as a Scaffold to Regulate Ras/Raf/MEK1/2 Activity in Human Liver and Colon Cancer Cells

Hui Peng, Tony W.H. Li, Heping Yang, Mary P. Moyer, Jose M. Mato, Shelly C. Lu

Am J Pathol. 2015 Apr; 185(4): 1135–1144. doi: 10.1016/j.ajpath.2014.12.016

PMCID:: PMC4380842

Abstract Article PDF–1.7M

Select item 36422229.

Methionine Adenosyltransferase 2B-GIT1 Interplay Activates MEK1-ERK1/2 to Induce Growth in Human Liver and Colon Cancer

Hui Peng, Lily Dara, Tony W.H. Li, Yuhua Zheng, Heping Yang, Lauda Maria Tomasi, Ivan Tomasi, Pasquale Giordano, Jose M. Mato, Shelly C. Lu

Hepatology. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Hepatology. 2013 Jun; 57(6): 2299–2313. Published online 2013 May 14. doi: 10.1002/hep.26258

PMCID:: PMC3642222

Abstract Article PDF–2.1M

Select item 319889810.

Methionine Adenosyltransferase 2A/2B and Methylation: Gene Sequence Variation and Functional Genomics

Kendra K. S. Nordgren, Yi Peng, Linda L. Pelleymounter, Irene Moon, Ryan Abo, Qiping Feng, Bruce Eckloff, Vivien C. Yee, Eric Wieben, Richard M. Weinshilboum

Drug Metab Dispos. 2011 Nov; 39(11): 2135–2147. doi: 10.1124/dmd.111.040857

PMCID:: PMC3198898

Abstract Article PDF–2.4M

Select item 288841311.

Novel Function and Intracellular Localization of Methionine Adenosyltransferase 2β Splicing Variants

Meng Xia, Yongheng Chen, Ling-Chi Wang, Ebrahim Zandi, Heping Yang, Sean Bemanian, M. Luz Martínez-Chantar, José M. Mato, Shelly C. Lu

J Biol Chem. 2010 Jun 25; 285(26): 20015–20021. Published online 2010 Apr 26. doi: 10.1074/jbc.M109.094821

PMCID:: PMC2888413

Abstract Article PDF–1.3M

Select item 238712512.

Leptin’s Mitogenic Effect in Human Liver Cancer Cells Requires Induction of Both Methionine Adenosyltransferase 2A and 2β

Komal Ramani, Heping Yang, Meng Xia, Ainhoa Iglesias Ara, José M. Mato, Shelly C. Lu

Hepatology. Author manuscript; available in PMC 2008 May 19.

Published in final edited form as: Hepatology. 2008 Feb; 47(2): 521–531. doi: 10.1002/hep.22064

PMCID:: PMC2387125

Abstract Article PDF–957K

Select item 652193213.

MAT2B promotes proliferation and inhibits apoptosis in osteosarcoma by targeting epidermal growth factor receptor and proliferating cell nuclear antigen

Yuan Yuan, Yonggang Wang, Zimei Liu, Yong Sun, Yang Yao, Wenxi Yu, Zan Shen

Int J Oncol. 2019 Jun; 54(6): 2019–2029. Published online 2019 Mar 27. doi: 10.3892/ijo.2019.4764

PMCID:: PMC6521932

Abstract Article PDF–1.9M

Select item 374348814.

Methionine Adenosyltransferase 2B, HuR, and Sirtuin 1 Protein Cross-talk Impacts on the Effect of Resveratrol on Apoptosis and Growth in Liver Cancer Cells

Heping Yang, Yuhua Zheng, Tony W. H. Li, Hui Peng, David Fernandez-Ramos, María L. Martínez-Chantar, Adriana L. Rojas, José M. Mato, Shelly C. Lu

J Biol Chem. 2013 Aug 9; 288(32): 23161–23170. Published online 2013 Jun 28. doi: 10.1074/jbc.M113.487157

Correction in:: J Biol Chem. 2014 Jan 10; 289(2): 696.

PMCID:: PMC3743488

Abstract Article PDF–1.9M

Select item 379326115.

Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits

Naeem Shafqat, Joao R. C. Muniz, Ewa S. Pilka, Evangelos Papagrigoriou, Frank vonDelft, Udo Oppermann, Wyatt W. Yue

Biochem J. 2013 May 15; 452(Pt 1): 27–36. Prepublished online 2013 Feb 20. Published online 2013 Apr 25. doi: 10.1042/BJ20121580

PMCID:: PMC3793261

Abstract Article PDF–2.4M

Select item 499345516.

The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases

Claudia Pérez, Francisco J. Pérez-Zúñiga, Francisco Garrido, Edel Reytor, Francisco Portillo, María A. Pajares

PLoS One. 2016; 11(8): e0161672. Published online 2016 Aug 22. doi: 10.1371/journal.pone.0161672

Correction in:: PLoS One. 2016; 11(9): e0163761.

PMCID:: PMC4993455

Abstract Article PDF–3.8M

Select item 410792417.

Structure and function study of the complex that synthesizes S-adenosylmethionine

Ben Murray, Svetlana V. Antonyuk, Alberto Marina, Sebastiaan M. Van Liempd, Shelly C. Lu, Jose M. Mato, S. Samar Hasnain, Adriana L. Rojas

IUCrJ. 2014 Jul 1; 1(Pt 4): 240–249. Published online 2014 Jun 12. doi: 10.1107/S2052252514012585

PMCID:: PMC4107924

Abstract Article PDF–1.8M

Select item 279032618.

Genetic Association Study of Putative Functional Single Nucleotide Polymorphisms of Genes in Folate Metabolism and Spina Bifida

Carla A. Martinez, Hope Northrup, Jone-Ing Lin, Alanna C. Morrison, Jack M. Fletcher, Gayle H. Tyerman, Kit Sing Au

Am J Obstet Gynecol. Author manuscript; available in PMC 2010 Oct 1.

Published in final edited form as: Am J Obstet Gynecol. 2009 Oct; 201(4): 394.e1–394.11. Published online 2009 Aug 15. doi: 10.1016/j.ajog.2009.06.042

PMCID:: PMC2790326

Abstract Article PDF–415K

Select item 370509519.

Linkage and association of successful aging to the 6q25 region in large Amish kindreds

Digna R. Velez Edwards, John R. Gilbert, James E. Hicks, Jamie L. Myers, Lan Jiang, Anna C. Cummings, Shengru Guo, Paul J. Gallins, Ioanna Konidari, Laura Caywood, Lori Reinhart-Mercer, Denise Fuzzell, Claire Knebusch, Renee Laux, Charles E. Jackson, Margaret A. Pericak-Vance, Jonathan L. Haines, William K. Scott

Age (Dordr) 2013 Aug; 35(4): 1467–1477. Published online 2012 Jul 7. doi: 10.1007/s11357-012-9447-1

PMCID:: PMC3705095

Abstract Article PDF–327K

Select item 314561420.

Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium

Rozenn N. Lemaitre, Toshiko Tanaka, Weihong Tang, Ani Manichaikul, Millennia Foy, Edmond K. Kabagambe, Jennifer A. Nettleton, Irena B. King, Lu-Chen Weng, Sayanti Bhattacharya, Stefania Bandinelli, Joshua C. Bis, Stephen S. Rich, David R. Jacobs, Jr., Antonio Cherubini, Barbara McKnight, Shuang Liang, Xiangjun Gu, Kenneth Rice, Cathy C. Laurie, Thomas Lumley, Brian L. Browning, Bruce M. Psaty, Yii-Der I. Chen, Yechiel Friedlander, Luc Djousse, Jason H. Y. Wu, David S. Siscovick, André G. Uitterlinden, Donna K. Arnett, Luigi Ferrucci, Myriam Fornage, Michael Y. Tsai, Dariush Mozaffarian, Lyn M. Steffen

PLoS Genet. 2011 Jul; 7(7): e1002193. Published online 2011 Jul 28. doi: 10.1371/journal.pgen.1002193

PMCID:: PMC3145614

Abstract Article PDF–998K

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