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Items: 1 to 20 of 108

1.
Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing
Songqing Li, Shang L. Lian, Joanna J. Moser, Mark L. Fritzler, Marvin J. Fritzler, Minoru Satoh, Edward K. L. Chan
J Cell Sci. Author manuscript; available in PMC 2020 Nov 27.
Published in final edited form as: J Cell Sci. 2008 Dec 15; 121(Pt 24): 4134–4144. doi: 10.1242/jcs.036905
PMCID:
PMC7695043
AbstractArticlePDF–1.5M
2.
Structural Dynamics of the GW182 Silencing Domain Including its RNA Recognition motif (RRM) Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry
Maja K. Cieplak-Rotowska, Krzysztof Tarnowski, Marcin Rubin, Marc R. Fabian, Nahum Sonenberg, Michal Dadlez, Anna Niedzwiecka
J Am Soc Mass Spectrom. 2018; 29(1): 158–173. Published online 2017 Oct 27. doi: 10.1007/s13361-017-1830-9
PMCID:
PMC5785596
AbstractArticlePDF–2.2M
3.
Control of the localization and function of a miRNA silencing component TNRC6A by Argonaute protein
Kenji Nishi, Tomoko Takahashi, Masataka Suzawa, Takuya Miyakawa, Tatsuya Nagasawa, Yvelt Ming, Masaru Tanokura, Kumiko Ui-Tei
Nucleic Acids Res. 2015 Nov 16; 43(20): 9856–9873. Published online 2015 Oct 7. doi: 10.1093/nar/gkv1026
PMCID:
PMC4787778
AbstractArticlePDF–8.8M
4.
Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus
Kenji Nishi, Ai Nishi, Tatsuya Nagasawa, Kumiko Ui-Tei
RNA. 2013 Jan; 19(1): 17–35. doi: 10.1261/rna.034769.112
PMCID:
PMC3527724
AbstractArticlePDF–2.6M
5.
Mammalian GW220/TNGW1 is essential for the formation of GW/P bodies containing miRISC
Virginia Castilla-Llorente, Lee Spraggon, Miwako Okamura, Saif Naseeruddin, Matthew Adamow, Sarah Qamar, Jidong Liu
J Cell Biol. 2012 Aug 20; 198(4): 529–544. doi: 10.1083/jcb.201201153
PMCID:
PMC3514032
AbstractArticlePDF–4.4M
6.
Divergent GW182 functional domains in the regulation of translational silencing
Bing Yao, Songqing Li, Hyun Min Jung, Shang L. Lian, Grant X. Abadal, Frank Han, Marvin J. Fritzler, Edward K. L. Chan
Nucleic Acids Res. 2011 Apr; 39(7): 2534–2547. Published online 2010 Dec 2. doi: 10.1093/nar/gkq1099
PMCID:
PMC3074120
AbstractArticlePDF–6.3M
7.
A role for the P-body component, GW182, in microRNA function
Jidong Liu, Fabiola V. Rivas, James Wohlschlegel, John R. Yates, III, Roy Parker, Gregory J. Hannon
Nat Cell Biol. Author manuscript; available in PMC 2007 Feb 23.
Published in final edited form as: Nat Cell Biol. 2005 Dec; 7(12): 1261–1266. Published online 2005 Nov 13. doi: 10.1038/ncb1333
Correction in:
volume 8 on page 100
PMCID:
PMC1804202
AbstractArticlePDF–1.0M
8.
Formation of GW bodies is a consequence of microRNA genesis
Kaleb M Pauley, Theophany Eystathioy, Andrew Jakymiw, John C Hamel, Marvin J Fritzler, Edward K L Chan
EMBO Rep. 2006 Sep; 7(9): 904–910. Published online 2006 Aug 11. doi: 10.1038/sj.embor.7400783
PMCID:
PMC1559661
AbstractArticlePDF–207K
9.
The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies
THEOPHANY EYSTATHIOY, ANDREW JAKYMIW, EDWARD K.L. CHAN, BERTRAND SÉRAPHIN, NICOLAS COUGOT, MARVIN J. FRITZLER
RNA. 2003 Oct; 9(10): 1171–1173. doi: 10.1261/rna.5810203
PMCID:
PMC1370480
AbstractArticlePDF–119K
10.
A Phosphorylated Cytoplasmic Autoantigen, GW182, Associates with a Unique Population of Human mRNAs within Novel Cytoplasmic Speckles
Theophany Eystathioy, Edward K. L. Chan, Scott A. Tenenbaum, Jack D. Keene, Kevin Griffith, Marvin J. Fritzler
Mol Biol Cell. 2002 Apr; 13(4): 1338–1351. doi: 10.1091/mbc.01-11-0544
PMCID:
PMC102273
AbstractArticlePDF–1.5M
11.
Hypoxic BMSC-derived exosomal miR-652-3p promotes proliferation and metastasis of hepatocarcinoma cancer cells via targeting TNRC6A
Mei Li, Pengtao Zhai, Xudong Mu, Juanrong Song, Huilin Zhang, Juan Su
Aging (Albany NY) 2023 Nov 30; 15(22): 12780–12793. Published online 2023 Nov 16. doi: 10.18632/aging.205025
PMCID:
PMC10713425
AbstractArticlePDF–1.9M
12.
RNA helicase DDX6 and scaffold protein GW182 in P-bodies promote biogenesis of stress granules
Vladimir Majerciak, Tongqing Zhou, Michael J Kruhlak, Zhi-Ming Zheng
Nucleic Acids Res. 2023 Sep 22; 51(17): 9337–9355. Published online 2023 Jul 10. doi: 10.1093/nar/gkad585
PMCID:
PMC10516652
AbstractArticlePDF–3.1M
13.
Identification of Phosphorylated Amino Acids in Human TNRC6A C-Terminal Region and Their Effects on the Interaction with the CCR4-NOT Complex
Fusako Munakata, Masataka Suzawa, Kumiko Ui-Tei
Genes (Basel) 2021 Feb; 12(2): 271. Published online 2021 Feb 13. doi: 10.3390/genes12020271
PMCID:
PMC7917804
AbstractArticlePDF–1.3M
14.
Multivalent recruitment of human Argonaute by GW182
Elad Elkayam, Christopher R. Faehnle, Marjorie Morales, Jingchuan Sun, Huilin Li, Leemor Joshua-Tor
Mol Cell. Author manuscript; available in PMC 2018 Aug 17.
Published in final edited form as: Mol Cell. 2017 Aug 17; 67(4): 646–658.e3. Published online 2017 Aug 3. doi: 10.1016/j.molcel.2017.07.007
PMCID:
PMC5915679
AbstractArticlePDF–1.8M
15.
Structural characterisation of TNRC6A nuclear localisation signal in complex with importin-alpha
Jessica J. Chaston, Alastair Gordon Stewart, Mary Christie
PLoS One. 2017; 12(8): e0183587. Published online 2017 Aug 24. doi: 10.1371/journal.pone.0183587
PMCID:
PMC5570423
AbstractArticlePDF–4.6M
16.
Ethanol Facilitates HCV Replication via Upregulation of GW182 and HSP90 in Human Hepatoma Cells
Terence N. Bukong, Wei Hou, Karen Kodys, Gyongyi Szabo
Hepatology. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: Hepatology. 2013 Jan; 57(1): 70–80. doi: 10.1002/hep.26010
PMCID:
PMC3540130
AbstractArticlePDF–1.8M
17.
Defining a new role of GW182 in maintaining miRNA stability
Bing Yao, Lan B La, Ying-Chi Chen, Lung-Ji Chang, Edward K L Chan
EMBO Rep. 2012 Dec; 13(12): 1102–1108. Published online 2012 Oct 23. doi: 10.1038/embor.2012.160
PMCID:
PMC3512404
AbstractArticlePDF–726K
18.
Localization of Double-stranded Small Interfering RNA to Cytoplasmic Processing Bodies Is Ago2 Dependent and Results in Up-Regulation of GW182 and Argonaute-2
Aarti Jagannath, Matthew J.A. Wood
Mol Biol Cell. 2009 Jan 1; 20(1): 521–529. doi: 10.1091/mbc.E08-08-0796
PMCID:
PMC2613116
AbstractArticlePDF–444K
19.
Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing
Samantha T. Johnson, Yongjun Chu, Jing Liu, David R. Corey
RNA. 2021 Sep; 27(9): 1004–1016. doi: 10.1261/rna.078709.121
PMCID:
PMC8370741
AbstractArticlePDF–3.4M
20.
Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes
Zhongtian Liu, Samantha T. Johnson, Zhiying Zhang, David R. Corey
Nucleic Acid Ther. 2019 Dec 1; 29(6): 323–334. Published online 2019 Dec 2. doi: 10.1089/nat.2019.0815
PMCID:
PMC6885777
AbstractArticlePDF–755K

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