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Select item 86178711.

Distinct Morphological and Behavioural Alterations in ENU-Induced Heterozygous Trpc7^K810Stop Mutant Mice

Birgit Rathkolb, Maike Howaldt, Stefan Krebs, Petra Prückl, Susanne Sauer, Martin Hrabě de Angelis, Bernhard Aigner

Genes (Basel) 2021 Nov; 12(11): 1732. Published online 2021 Oct 29. doi: 10.3390/genes12111732

PMCID:: PMC8617871

Abstract Article PDF–837K

Select item 80916992.

TRPC7 regulates the electrophysiological functions of embryonic stem cell-derived cardiomyocytes

Xianji Liu, Rui Zhao, Qianqian Ding, Xiaoqiang Yao, Suk Ying Tsang

Stem Cell Res Ther. 2021; 12: 262. Published online 2021 May 3. doi: 10.1186/s13287-021-02308-7

PMCID:: PMC8091699

Abstract Article PDF–5.3M

Select item 41281383.

Critical role of canonical transient receptor potential channel 7 in initiation of seizures

Kevin D. Phelan, U Thaung Shwe, Joel Abramowitz, Lutz Birnbaumer, Fang Zheng

Proc Natl Acad Sci U S A. 2014 Aug 5; 111(31): 11533–11538. Published online 2014 Jul 21. doi: 10.1073/pnas.1411442111

PMCID:: PMC4128138

Abstract Article PDF–1.3M

Select item 36906904.

Molecular determinants for cardiovascular TRPC6 channel regulation by Ca²⁺/calmodulin-dependent kinase II

Juan Shi, Naomi Geshi, Shinichi Takahashi, Shigeki Kiyonaka, Jun Ichikawa, Yaopeng Hu, Yasuo Mori, Yushi Ito, Ryuji Inoue

J Physiol. 2013 Jun 1; 591(Pt 11): 2851–2866. Published online 2013 Mar 25. doi: 10.1113/jphysiol.2013.251249

PMCID:: PMC3690690

Abstract Article PDF–1.2M

Select item 69747165.

Nociceptive transient receptor potential canonical 7 (TRPC7) mediates aging‐associated tumorigenesis induced by ultraviolet B

Wen‐Li Hsu, Ming‐Hsien Tsai, Ching‐Ying Wu, Jui‐Lin Liang, Jian‐He Lu, Jennifer S. Kahle, Hsin‐Su Yu, Chia‐Jung Yen, Chen‐Tung Yen, Yi‐Chun Hsieh, Yung‐Yun Huang, Li‐Ching Lin, Tsung‐Fu Tsai, Chu‐Huang Chen, Tohru Yoshioka

Aging Cell. 2020 Jan; 19(1): e13075. Published online 2019 Nov 21. doi: 10.1111/acel.13075

PMCID:: PMC6974716

Abstract Article PDF–3.3M

Select item 54686546.

Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries

Xiju He, Shoutian Li, Benju Liu, Sebastian Susperreguy, Karina Formoso, Jinghong Yao, Jinsong Kang, Anbing Shi, Lutz Birnbaumer, Yanhong Liao

Proc Natl Acad Sci U S A. 2017 Jun 6; 114(23): E4582–E4591. Published online 2017 May 19. doi: 10.1073/pnas.1621384114

PMCID:: PMC5468654

Abstract Article PDF–1.9M

Select item 61073777.

Melanopsin phototransduction is repurposed by ipRGC subtypes to shape the function of distinct visual circuits

Takuma Sonoda, Seul Ki Lee, Lutz Birnbaumer, Tiffany M. Schmidt

Neuron. Author manuscript; available in PMC 2019 Aug 22.

Published in final edited form as: Neuron. 2018 Aug 22; 99(4): 754–767.e4. Published online 2018 Jul 12. doi: 10.1016/j.neuron.2018.06.032

PMCID:: PMC6107377

Abstract Article PDF–2.5M

Select item 30762938.

Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC channel subunits

Claudio E. Perez-Leighton, Tiffany M. Schmidt, Joel Abramowitz, Lutz Birnbaumer, Paulo Kofuji

Eur J Neurosci. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: Eur J Neurosci. 2011 Mar; 33(5): 856–867. Published online 2011 Jan 24. doi: 10.1111/j.1460-9568.2010.07583.x

PMCID:: PMC3076293

Abstract Article PDF–1.5M

Select item 28724589.

TRPC channels are necessary mediators of pathologic cardiac hypertrophy

Xu Wu, Petra Eder, Baojun Chang, Jeffery D. Molkentin

Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15): 7000–7005. Published online 2010 Mar 29. doi: 10.1073/pnas.1001825107

PMCID:: PMC2872458

Abstract Article PDF–866K

Select item 1114828210.

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer

Yanting Lin, Rui Gao, Dongquan Jing, Yiming Liu, Huijuan Da, Lutz Birnbaumer, Yong Yang, Xinghua Gao, Zhenhua Gao, Qiuhua Cao

Front Pharmacol. 2024; 15: 1392328. Published online 2024 May 21. doi: 10.3389/fphar.2024.1392328

PMCID:: PMC11148282

Abstract Article PDF–5.1M

Select item 1075619211.

Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs

Guang Li, Lujing Chen, Zheng Jiang, King-Wai Yau

Proc Natl Acad Sci U S A. 2023 Dec 26; 120(52): e2315282120. Published online 2023 Dec 18. doi: 10.1073/pnas.2315282120

PMCID:: PMC10756192

Abstract Article PDF–4.0M

Select item 719087412.

RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways

Karina Formoso, Sebastian Susperreguy, Marc Freichel, Lutz Birnbaumer

Sci Rep. 2020; 10: 7227. Published online 2020 Apr 29. doi: 10.1038/s41598-020-61177-x

PMCID:: PMC7190874

Abstract Article PDF–4.0M

Select item 425254613.

Metabolism Regulates the Spontaneous Firing of Substantia Nigra Pars Reticulata Neurons via K_ATP and Nonselective Cation Channels

Andrew Lutas, Lutz Birnbaumer, Gary Yellen

J Neurosci. 2014 Dec 3; 34(49): 16336–16347. doi: 10.1523/JNEUROSCI.1357-14.2014

PMCID:: PMC4252546

Abstract Article PDF–570K

Select item 490256114.

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

Andrew Lutas, Carolina Lahmann, Magali Soumillon, Gary Yellen

eLife. 2016; 5: e15271. Published online 2016 May 13. doi: 10.7554/eLife.15271

PMCID:: PMC4902561

Abstract Article PDF–1007K

Select item 327089115.

Melanopsin Signaling in Mammalian Iris and Retina

T. Xue, M. T. H. Do, A. Riccio, Z. Jiang, J. Hsieh, H. C. Wang, S. L. Merbs, D. S. Welsbie, T. Yoshioka, P. Weissgerber, S. Stolz, V. Flockerzi, M. Freichel, M. I. Simon, D. E. Clapham, K.-W. Yau

Nature. Author manuscript; available in PMC 2012 May 3.

Published in final edited form as: Nature. 2011 Nov 3; 479(7371): 67–73. Published online 2011 Nov 2. doi: 10.1038/nature10567