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Select item 87923621.

RNA sequencing uncovers alterations in corneal endothelial metabolism, pump and barrier functions of Slc4a11 KO mice

Diego G. Ogando, Joseph A. Bonanno

Exp Eye Res. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Exp Eye Res. 2022 Jan; 214: 108884. Published online 2021 Dec 3. doi: 10.1016/j.exer.2021.108884

PMCID:: PMC8792362

Abstract Article PDF–2.3M

Select item 85366602.

Altered gene expression in slc4a11^−/− mouse cornea highlights SLC4A11 roles

Bernardo V. Alvarez, Marilyse Piché, Carolin Aizouki, Fariha Rahman, Jonathan M. J. Derry, Isabelle Brunette, Joseph R. Casey

Sci Rep. 2021; 11: 20885. Published online 2021 Oct 22. doi: 10.1038/s41598-021-98921-w

PMCID:: PMC8536660

Abstract Article PDF–2.3M

Select item 84587823.

Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy

Rajalekshmy Shyam, Diego G. Ogando, Moonjung Choi, Paloma B. Liton, Joseph A. Bonanno

Invest Ophthalmol Vis Sci. 2021 Sep; 62(12): 15. Published online 2021 Sep 17. doi: 10.1167/iovs.62.12.15

PMCID:: PMC8458782

Abstract Article PDF–3.2M

Select item 84347534.

Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium

Moonjung Choi, Joseph A. Bonanno

Invest Ophthalmol Vis Sci. 2021 Sep; 62(12): 4. Published online 2021 Sep 9. doi: 10.1167/iovs.62.12.4

PMCID:: PMC8434753

Abstract Article PDF–3.8M

Select item 76958345.

Borax induces osteogenesis by stimulating NaBC1 transporter via activation of BMP pathway

Patricia Rico, Aleixandre Rodrigo-Navarro, Laura Sánchez Pérez, Manuel Salmeron-Sanchez

Commun Biol. 2020; 3: 717. Published online 2020 Nov 27. doi: 10.1038/s42003-020-01449-4

PMCID:: PMC7695834

Abstract Article PDF–3.2M

Select item 73244376.

Corneal Endothelial Pump Coupling to Lactic Acid Efflux in the Rabbit and Mouse

Shimin Li, Edward Kim, Diego G. Ogando, Joseph A. Bonanno

Invest Ophthalmol Vis Sci. 2020 Feb; 61(2): 7. Published online 2020 Feb 7. doi: 10.1167/iovs.61.2.7

PMCID:: PMC7324437

Abstract Article PDF–635K

Select item 69087397.

Slc4a11 disruption causes duct cell loss and impairs NaCl reabsorption in female mouse submandibular glands

Ning‐Yan Yang, Taro Mukaibo, Xin Gao, Ira Kurtz, James E. Melvin

Physiol Rep. 2019 Dec; 7(23): e14232. Published online 2019 Dec 12. doi: 10.14814/phy2.14232

PMCID:: PMC6908739

Abstract Article PDF–2.8M

Select item 55255558.

Conditionally Immortal Slc4a11^−/− Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11^−/− Mouse Model

Wenlin Zhang, Diego G. Ogando, Edward T. Kim, Moon-Jung Choi, Hongde Li, Jason M. Tenessen, Joseph A. Bonanno

Invest Ophthalmol Vis Sci. 2017 Jul; 58(9): 3723–3731. doi: 10.1167/iovs.17-21781

PMCID:: PMC5525555

Abstract Article PDF–1.2M

Select item 27853769.

Slc4a11 Gene Disruption in Mice: CELLULAR TARGETS OF SENSORINEURONAL ABNORMALITIES

Ivan A. Lopez, Mark I. Rosenblatt, Charles Kim, Gary C. Galbraith, Sherri M. Jones, Liyo Kao, Debra Newman, Weixin Liu, Stacey Yeh, Alexander Pushkin, Natalia Abuladze, Ira Kurtz

J Biol Chem. 2009 Sep 25; 284(39): 26882–26896. Published online 2009 Jul 8. doi: 10.1074/jbc.M109.008102

PMCID:: PMC2785376

Abstract Article PDF–5.4M

Select item 1025307210.

Corneal Edema in Inducible Slc4a11 Knockout Is Initiated by Mitochondrial Superoxide Induced Src Kinase Activation

Diego G. Ogando, Edward T. Kim, Shimin Li, Joseph A. Bonanno

Cells. 2023 Jun; 12(11): 1528. Published online 2023 Jun 1. doi: 10.3390/cells12111528

PMCID:: PMC10253072

Abstract Article PDF–13M

Select item 948499811.

Corneal dystrophy mutations R125H and R804H disable SLC4A11 by altering the extracellular pH dependence of the intracellular pK that governs H⁺(OH⁻) transport

Bianca N. Quade, Aniko Marshall, Mark D. Parker

Am J Physiol Cell Physiol. 2022 Oct 1; 323(4): C990–C1002. Published online 2022 Aug 22. doi: 10.1152/ajpcell.00221.2022

PMCID:: PMC9484998

Abstract Article

Select item 750021512.

pH dependence of the Slc4a11-mediated H⁺ conductance is influenced by intracellular lysine residues and modified by disease-linked mutations

Bianca N. Quade, Aniko Marshall, Mark D. Parker

Am J Physiol Cell Physiol. 2020 Aug 1; 319(2): C359–C370. Published online 2020 Jun 10. doi: 10.1152/ajpcell.00128.2020

PMCID:: PMC7500215

Abstract Article

Select item 653317413.

Expression of SLC4A11 protein in mouse and rat medulla: a candidate transporter involved in outer medullary ammonia recycling

Michael T. Gee, Ira Kurtz, Thomas L. Pannabecker

Physiol Rep. 2019 May; 7(10): e14089. Published online 2019 May 23. doi: 10.14814/phy2.14089

PMCID:: PMC6533174

Abstract Article PDF–2.1M

Select item 560827714.

Vps35-deficiency impairs SLC4A11 trafficking and promotes corneal dystrophy

Wei Liu, Fu-Lei Tang, Sen Lin, Kai Zhao, Lin Mei, Jian Ye, Wen-Cheng Xiong

PLoS One. 2017; 12(9): e0184906. Published online 2017 Sep 21. doi: 10.1371/journal.pone.0184906

PMCID:: PMC5608277

Abstract Article PDF–20M

Select item 286320915.

SLC4A11 Prevents Osmotic Imbalance Leading to Corneal Endothelial Dystrophy, Deafness, and Polyuria

Nicole Gröger, Henning Fröhlich, Hannes Maier, Andrea Olbrich, Sawa Kostin, Thomas Braun, Thomas Boettger

J Biol Chem. 2010 May 7; 285(19): 14467–14474. Published online 2010 Feb 25. doi: 10.1074/jbc.M109.094680

PMCID:: PMC2863209

Abstract Article PDF–3.7M

Select item 1100506516.

Characterization of a Novel Mouse Model for Fuchs Endothelial Corneal Dystrophy

Subashree Murugan, Viviane Souza de Campos, Sachin Anil Ghag, Matthew Ng, Rajalekshmy Shyam

Invest Ophthalmol Vis Sci. 2024 Apr; 65(4): 18. Published online 2024 Apr 8. doi: 10.1167/iovs.65.4.18

PMCID:: PMC11005065

Abstract Article PDF–4.5M

Select item 882655117.

Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump

Diego G. Ogando, Rajalekshmy Shyam, Edward T. Kim, Yen-Chiao Wang, Chia-Yang Liu, Joseph A. Bonanno

Invest Ophthalmol Vis Sci. 2021 Jun; 62(7): 28. Published online 2021 Jun 30. doi: 10.1167/iovs.62.7.28

PMCID:: PMC8826551

Abstract Article PDF–3.2M

Select item 388980818.

Transmembrane water-flux through SLC4A11: a route defective in genetic corneal diseases

Gonzalo L. Vilas, Sampath K. Loganathan, Jun Liu, Andri K. Riau, James D. Young, Jodhbir S. Mehta, Eranga N. Vithana, Joseph R. Casey

Hum Mol Genet. 2013 Nov 15; 22(22): 4579–4590. Published online 2013 Jun 27. doi: 10.1093/hmg/ddt307

PMCID:: PMC3889808

Abstract Article PDF–1.2M

Select item 263408519.

The European Renal Genome Project: An Integrated Approach Towards Understanding the Genetics of Kidney Development and Disease

TE Willnow, C Antignac, AW Brändli, EI Christensen, RD Cox, D Davidson, JA Davies, O Devuyst, G Eichele, ND Hastie, PJ Verroust, A Schedl, IC Meij

Organogenesis. 2005 Apr-Jun; 2(2): 42–47. doi: 10.4161/org.2.2.2118

PMCID:: PMC2634085

Abstract Article PDF–629K

Select item 357241020.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

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PMC Links for Gene (Select 269356) (27)
PMC
Mus musculus interferon induced transmembrane protein 1 (Ifitm1), transcript var...
Mus musculus interferon induced transmembrane protein 1 (Ifitm1), transcript variant 1, mRNA
gi|163310728|ref|NM_026820.3|

Nucleotide
Mus musculus spermine oxidase (Smox), transcript variant 2, mRNA
Mus musculus spermine oxidase (Smox), transcript variant 2, mRNA
gi|2772229905|ref|NM_145533.3|

Nucleotide
solute carrier family 4 member 11 isoform X3 [Mus musculus]
solute carrier family 4 member 11 isoform X3 [Mus musculus]
gi|1720399334|ref|XP_030107525.1|

Protein
Homo sapiens RIC1 homolog, RAB6A GEF complex partner 1 (RIC1), transcript varian...
Homo sapiens RIC1 homolog, RAB6A GEF complex partner 1 (RIC1), transcript variant 2, mRNA
gi|330864712|ref|NM_001135920.2|

Nucleotide

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