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Select item 110762851.

Specific exercise patterns generate an epigenetic molecular memory window that drives long-term memory formation and identifies ACVR1C as a bidirectional regulator of memory in mice

Ashley A. Keiser, Tri N. Dong, Enikö A. Kramár, Christopher W. Butler, Siwei Chen, Dina P. Matheos, Jacob S. Rounds, Alyssa Rodriguez, Joy H. Beardwood, Agatha S. Augustynski, Ameer Al-Shammari, Yasaman Alaghband, Vanessa Alizo Vera, Nicole C. Berchtold, Sharmin Shanur, Pierre Baldi, Carl W. Cotman, Marcelo A. Wood

Nat Commun. 2024; 15: 3836. Published online 2024 May 7. doi: 10.1038/s41467-024-47996-w

PMCID:: PMC11076285

Abstract Article PDF–3.0M

Select item 99774912.

Targeting activin receptor–like kinase 7 ameliorates adiposity and associated metabolic disorders

Min Zhao, Katsuhide Okunishi, Yun Bu, Osamu Kikuchi, Hao Wang, Tadahiro Kitamura, Tetsuro Izumi

JCI Insight. 2023 Feb 22; 8(4): e161229. Published online 2023 Feb 22. doi: 10.1172/jci.insight.161229

PMCID:: PMC9977491

Abstract Article PDF–9.7M

Select item 92249963.

The orphan ligand, activin C, signals through activin receptor-like kinase 7

Erich J Goebel, Luisina Ongaro, Emily C Kappes, Kylie Vestal, Elitza Belcheva, Roselyne Castonguay, Ravindra Kumar, Daniel J Bernard, Thomas B Thompson

eLife. 2022; 11: e78197. Published online 2022 Jun 23. doi: 10.7554/eLife.78197

PMCID:: PMC9224996

Abstract Article PDF–4.6M

Select item 47555804.

Alk7 Depleted Mice Exhibit Prolonged Cardiac Repolarization and Are Predisposed to Ventricular Arrhythmia

Shaozhen Ying, Hong Cao, He Hu, Xin Wang, Yanhong Tang, Congxin Huang

PLoS One. 2016; 11(2): e0149205. Published online 2016 Feb 16. doi: 10.1371/journal.pone.0149205

PMCID:: PMC4755580

Abstract Article PDF–1.7M

Select item 41390625.

Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity

Tingqing Guo, Patricia Marmol, Annalena Moliner, Marie Björnholm, Chao Zhang, Kevan M Shokat, Carlos F Ibanez

eLife. 2014; 3: e03245. Published online 2014 Aug 26. doi: 10.7554/eLife.03245

PMCID:: PMC4139062

Abstract Article PDF–2.2M

Select item 94281606.

Activin receptor-like kinase 7 promotes apoptosis of vascular smooth muscle cells via activating Smad2/3 signaling in diabetic atherosclerosis

Shengchuan Cao, Qiuhuan Yuan, Qianqian Dong, Xilong Liu, Weikang Liu, Xiaoxuan Zhai, Chuanxin Zhang, Han Liu, Mengxiong Tang, Shujian Wei, Yuguo Chen

Front Pharmacol. 2022; 13: 926433. Published online 2022 Aug 17. doi: 10.3389/fphar.2022.926433

PMCID:: PMC9428160

Abstract Article PDF–2.3M

Select item 72001617.

Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7

Patricia Marmol, Favio Krapacher, Carlos F Ibáñez

eLife. 2020; 9: e54721. Published online 2020 May 5. doi: 10.7554/eLife.54721

PMCID:: PMC7200161

Abstract Article PDF–1.1M

Select item 107936948.

Targeting the activin receptor 1C on CD4+ T cells for cancer immunotherapy

Ying Zheng, Andriana Lebid, Liam Chung, Juan Fu, Xiaoxu Wang, Andrea Otrocol, Jelani C. Zarif, Hong Yu, Nicolas J. Llosa, Drew M. Pardoll

Oncoimmunology. 2024; 13(1): 2297503. Published online 2024 Jan 8. doi: 10.1080/2162402X.2023.2297503

PMCID:: PMC10793694

Abstract Article PDF–3.8M

Select item 56068459.

Learning induces the translin/trax RNase complex to express activin receptors for persistent memory

Alan Jung Park, Robbert Havekes, Xiuping Fu, Rolf Hansen, Jennifer C Tudor, Lucia Peixoto, Zhi Li, Yen-Ching Wu, Shane G Poplawski, Jay M Baraban, Ted Abel

eLife. 2017; 6: e27872. Published online 2017 Sep 20. doi: 10.7554/eLife.27872

PMCID:: PMC5606845

Abstract Article PDF–1.2M

Select item 352603810.

Activin Receptor-Like Kinase 7 Suppresses Lipolysis to Accumulate Fat in Obesity Through Downregulation of Peroxisome Proliferator–Activated Receptor γ and C/EBPα

Satomi Yogosawa, Shin Mizutani, Yoshihiro Ogawa, Tetsuro Izumi

Diabetes. 2013 Jan; 62(1): 115–123. Published online 2012 Dec 13. doi: 10.2337/db12-0295

PMCID:: PMC3526038

Abstract Article PDF–1.9M

Select item 340456311.

Nodal induces apoptosis through activation of the ALK7 signaling pathway in pancreatic INS-1 β-cells

Fang Zhao, Fengjie Huang, Mengxiong Tang, Xiaoming Li, Nina Zhang, Akis Amfilochiadis, Yiming Li, Renming Hu, Tianru Jin, Chun Peng, Qinghua Wang

Am J Physiol Endocrinol Metab. 2012 Jul 1; 303(1): E132–E143. Published online 2012 May 1. doi: 10.1152/ajpendo.00074.2012

PMCID:: PMC3404563

Abstract Article

Select item 243823512.

Activin B receptor ALK7 is a negative regulator of pancreatic β-cell function

Philippe Bertolino, Rebecka Holmberg, Eva Reissmann, Olov Andersson, Per-Olof Berggren, Carlos F. Ibáñez

Proc Natl Acad Sci U S A. 2008 May 20; 105(20): 7246–7251. Published online 2008 May 14. doi: 10.1073/pnas.0801285105

PMCID:: PMC2438235

Abstract Article PDF–1.1M

Select item 243823613.

Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity

Olov Andersson, Marion Korach-Andre, Eva Reissmann, Carlos F. Ibáñez, Philippe Bertolino

Proc Natl Acad Sci U S A. 2008 May 20; 105(20): 7252–7256. Published online 2008 May 14. doi: 10.1073/pnas.0800272105

PMCID:: PMC2438236

Abstract Article PDF–1.3M

Select item 52222314.

ALK7, a Receptor for Nodal, Is Dispensable for Embryogenesis and Left-Right Patterning in the Mouse

Henrik Jörnvall, Eva Reissmann, Olov Andersson, Mehrnaz Mehrkash, Carlos F. Ibáñez

Mol Cell Biol. 2004 Nov; 24(21): 9383–9389. doi: 10.1128/MCB.24.21.9383-9389.2004

PMCID:: PMC522223

Abstract Article PDF–558K

Select item 667937015.

Nkx2-5 defines a subpopulation of pacemaker cells and is essential for the physiological function of the sinoatrial node in mice

Hua Li, Dainan Li, Yuzhi Wang, Zhen Huang, Jue Xu, Tianfang Yang, Linyan Wang, Qinghuang Tang, Chen-Leng Cai, Hai Huang, Yanding Zhang, YiPing Chen

Development. 2019 Jul 15; 146(14): dev178145. Published online 2019 Jul 25. doi: 10.1242/dev.178145

PMCID:: PMC6679370

Abstract Article

Select item 354699216.

Signaling through the TGF Beta-Activin Receptors ALK4/5/7 Regulates Testis Formation and Male Germ Cell Development

Denise C. Miles, Stephanie I. Wakeling, Jessica M. Stringer, Jocelyn A. van den Bergen, Dagmar Wilhelm, Andrew H. Sinclair, Patrick S. Western

PLoS One. 2013; 8(1): e54606. Published online 2013 Jan 16. doi: 10.1371/journal.pone.0054606

PMCID:: PMC3546992

Abstract Article PDF–7.3M

Select item 152515517.

Growth differentiation factor 11 signals through the transforming growth factor-β receptor ALK5 to regionalize the anterior–posterior axis

Olov Andersson, Eva Reissmann, Carlos F Ibáñez

EMBO Rep. 2006 Aug; 7(8): 831–837. Published online 2006 Jul 14. doi: 10.1038/sj.embor.7400752

PMCID:: PMC1525155

Abstract Article PDF–279K

Select item 667362618.

The Neonatal Ventromedial Hypothalamus Transcriptome Reveals Novel Markers with Spatially Distinct Patterning

Deborah M. Kurrasch, Clement C. Cheung, Florence Y. Lee, Phu V. Tran, Kenji Hata, Holly A. Ingraham

J Neurosci. 2007 Dec 12; 27(50): 13624–13634. doi: 10.1523/JNEUROSCI.2858-07.2007

PMCID:: PMC6673626

Abstract Article PDF–638K

Select item 418841619.

Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons

Simona Lodato, Bradley J Molyneaux, Emanuela Zuccaro, Loyal A Goff, Hsu-Hsin Chen, Wen Yuan, Alyssa Meleski, Emi Takahashi, Shaun Mahony, John L Rinn, David K Gifford, Paola Arlotta

Nat Neurosci. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Nat Neurosci. 2014 Aug; 17(8): 1046–1054. Published online 2014 Jul 6. doi: 10.1038/nn.3757