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Select item 92900721.

Pathological significance and prognostic role of LATS2 in prostate cancer

Tsuyoshi Matsuda, Yasuyoshi Miyata, Yuichiro Nakamura, Asato Otsubo, Yuta Mukae, Junki Harada, Kensuke Mitsunari, Tomohiro Matsuo, Kojiro Ohba, Bungo Furusato, Hideki Sakai

Prostate. 2021 Nov 1; 81(15): 1252–1260. Published online 2021 Sep 7. doi: 10.1002/pros.24226

PMCID:: PMC9290072

Abstract Article PDF–3.4M

Select item 88100272.

Large tumor suppressor 2 is a prognostic biomarker and correlated with immune infiltrates in colorectal cancer

Chengwen Zhao, Jianping Chen, Yonghui Liu, Shaoqing Ju, Guihua Wang, Xudong Wang

Bioengineered. 2021; 12(2): 11648–11661. Published online 2021 Dec 19. doi: 10.1080/21655979.2021.1996513

PMCID:: PMC8810027

Abstract Article PDF–2.1M

Select item 87266793.

Deathly triangle for pancreatic β-cells: Hippo pathway-MTORC1-autophagy

Amin Ardestani, Kathrin Maedler

Autophagy. 2021; 17(12): 4494–4496. Published online 2021 Sep 1. doi: 10.1080/15548627.2021.1972404

PMCID:: PMC8726679

Abstract Article PDF–379K

Select item 75418504.

Promoter Hypermethylation of LATS2 Gene in Oral Squamous Cell Carcinoma (OSCC) among North Indian Population

Harsh Goel, Saloni Singhal, Runjhun Mathur, Saima Syeda, Rishi Kumar Gupta, Anshuman Kumar, Anju Shrivastava, Abhimanyu Kumar Jha

Asian Pac J Cancer Prev. 2020 May; 21(5): 1283–1287. doi: 10.31557/APJCP.2020.21.5.1283

PMCID:: PMC7541850

Abstract Article PDF–405K

Select item 70397855.

过表达大肿瘤抑制因子2对口腔鳞状细胞癌细胞增殖和凋亡的影响

岳增文, 王树斌, 刘进忠

Hua Xi Kou Qiang Yi Xue Za Zhi. 2018 Dec; 36(6): 609–612. Chinese. doi: 10.7518/hxkq.2018.06.005

PMCID:: PMC7039785

Abstract Article PDF–1.6M

Select item 65291346.

The clinical significance and biological function of large tumour suppressor 2 in hepatocellular carcinoma

Rong Liang, Yan Lin, Chun‐Ling Yuan, Zhi‐Hui Liu, Yong‐Qiang Li, Xiao‐Ling Luo, Jia‐Zhou Ye, Hai‐Hong Ye

Cell Prolif. 2017 Jun; 50(3): e12340. Published online 2017 Mar 1. doi: 10.1111/cpr.12340

PMCID:: PMC6529134

Abstract Article PDF–858K

Select item 64480877.

LATS2 inhibits cell proliferation and metastasis through the Hippo signaling pathway in glioma

Chengyong Guo, Chaohui Liang, Jipeng Yang, Hongchao Hu, Bo Fan, Xin Liu

Oncol Rep. 2019 May; 41(5): 2753–2761. Published online 2019 Mar 14. doi: 10.3892/or.2019.7065

PMCID:: PMC6448087

Abstract Article PDF–822K

Select item 44511098.

Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas

Susan Y. Luo, Ko-Yung Sit, Alan D.L. Sihoe, Wai-Sing Suen, Wing-Kuk Au, Ximing Tang, Edmond S.K. Ma, Wai-Kong Chan, Ignacio I. Wistuba, John D. Minna, George S.W. Tsao, David C.L. Lam

Lung Cancer. Author manuscript; available in PMC 2015 Jun 2.

Published in final edited form as: Lung Cancer. 2014 Aug; 85(2): 282–292. Published online 2014 Jun 16. doi: 10.1016/j.lungcan.2014.05.025

PMCID:: PMC4451109

Abstract Article PDF–1.8M

Select item 33152099.

Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming

Han Qin, Kathryn Blaschke, Grace Wei, Yuki Ohi, Laure Blouin, Zhongxia Qi, Jingwei Yu, Ru-Fang Yeh, Matthias Hebrok, Miguel Ramalho-Santos

Hum Mol Genet. 2012 May 1; 21(9): 2054–2067. Published online 2012 Jan 27. doi: 10.1093/hmg/dds023

PMCID:: PMC3315209

Abstract Article PDF–645K

Select item 295894910.

LATS2 is De-methylated and Overexpressed in Nasopharyngeal Carcinoma and Predicts Poor Prognosis

Yan Zhang, Chun-Fang Hu, Jing Chen, Li-Xu Yan, Yi-Xin Zeng, Jian-Yong Shao

BMC Cancer. 2010; 10: 538. Published online 2010 Oct 8. doi: 10.1186/1471-2407-10-538

PMCID:: PMC2958949

Abstract Article PDF–2.1M

Select item 881009211.

MicroRNA miR-4709-3p targets Large Tumor Suppressor Kinase 2 (LATS2) and induces obstructive renal fibrosis through Hippo signaling

Zexiang Jiang, Weiping Xia, Guoyu Dai, Bo Zhang, Yang Li, Xiang Chen

Bioengineered. 2021; 12(2): 12357–12371. Published online 2021 Dec 21. doi: 10.1080/21655979.2021.2002493

PMCID:: PMC8810092

Abstract Article PDF–3.2M

Select item 880651612.

LncRNA MYLK-AS1 acts as an oncogene by epigenetically silencing large tumor suppressor 2 (LATS2) in gastric cancer

Juan Luo, Huifei Xiang

Bioengineered. 2021; 12(1): 3101–3112. Published online 2021 Jun 28. doi: 10.1080/21655979.2021.1944019

PMCID:: PMC8806516

Abstract Article PDF–2.6M

Select item 839047913.

MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor

Xiaochong Deng, Danrong Ye, Kaiyao Hua, Hongming Song, Qifeng Luo, Amik Munankarmy, Diya Liu, Baian Zhou, Wenfang Zheng, Xiqian Zhou, Changle Ji, Xuehui Wang, Yunhe Yu, Lin Fang

Cell Death Dis. 2021 Sep; 12(9): 810. Published online 2021 Aug 26. doi: 10.1038/s41419-021-04105-9

PMCID:: PMC8390479

Abstract Article PDF–7.7M

Select item 788548514.

A specific tRNA half, 5’tiRNA-His-GTG, responds to hypoxia via the HIF1α/ANG axis and promotes colorectal cancer progression by regulating LATS2

En-Wei Tao, Hao-Lian Wang, Wing Yin Cheng, Qian-Qian Liu, Ying-Xuan Chen, Qin-Yan Gao

J Exp Clin Cancer Res. 2021; 40: 67. Published online 2021 Feb 15. doi: 10.1186/s13046-021-01836-7

PMCID:: PMC7885485

Abstract Article PDF–3.1M

Select item 723610815.

Association analysis between SNPs in LATS1 and LATS2 and non-cardia gastric cancer

Li-cong Ma, Xu-yang Tian, Fang Gao, Wen-jie Dong, Tong Dang, Yan-bin Jia

BMC Gastroenterol. 2020; 20: 155. Published online 2020 May 18. doi: 10.1186/s12876-020-01250-x

PMCID:: PMC7236108

Abstract Article PDF–500K

Select item 695782816.

The Hippo Kinase LATS2 Controls Helicobacter pylori-Induced Epithelial-Mesenchymal Transition and Intestinal Metaplasia in Gastric Mucosa

Silvia Elena Molina-Castro, Camille Tiffon, Julie Giraud, Hélène Boeuf, Elodie Sifre, Alban Giese, Geneviève Belleannée, Philippe Lehours, Emilie Bessède, Francis Mégraud, Pierre Dubus, Cathy Staedel, Christine Varon

Cell Mol Gastroenterol Hepatol. 2020; 9(2): 257–276. Published online 2019 Oct 24. doi: 10.1016/j.jcmgh.2019.10.007

PMCID:: PMC6957828

Abstract Article PDF–5.3M

Select item 645075117.

Cell type-dependent function of LATS1/2 in cancer cell growth

Wei-Wei Pan, Toshiro Moroishi, Ja Hyun Koo, Kun-Liang Guan

Oncogene. Author manuscript; available in PMC 2019 Jun 10.

Published in final edited form as: Oncogene. 2019 Apr; 38(14): 2595–2610. Published online 2018 Dec 10. doi: 10.1038/s41388-018-0610-8

PMCID:: PMC6450751

Abstract Article PDF–2.5M

Select item 639960718.

YAP1‐LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis

Chunbo He, Xiangmin Lv, Cong Huang, Guohua Hua, Bowen Ma, Xingcheng Chen, Peter C Angeletti, Jixin Dong, Jin Zhou, Zhengfeng Wang, Bo R Rueda, John S Davis, Cheng Wang

EMBO Rep. 2019 Mar; 20(3): e44948. Published online 2019 Feb 12. doi: 10.15252/embr.201744948