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Select item 104457591.

GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy

Xiaohui Li, Jialu Liu, Mengru Zeng, Kexin Yang, Shumin Zhang, Yifei Liu, Xiangxiang Yin, Chanyue Zhao, Wenpeng Wang, Li Xiao

Front Immunol. 2023; 14: 1127612. Published online 2023 Aug 9. doi: 10.3389/fimmu.2023.1127612

PMCID:: PMC10445759

Abstract Article PDF–10M

Select item 94827462.

GBP2 acts as a member of the interferon signalling pathway in lupus nephritis

Yuan Zhang, Yinping Liao, Qing Hang, Dong Sun, Ya Liu

BMC Immunol. 2022; 23: 44. Published online 2022 Sep 17. doi: 10.1186/s12865-022-00520-5

PMCID:: PMC9482746

Abstract Article PDF–3.9M

Select item 34368813.

Suppression of IFN-Induced Transcription Underlies IFN Defects Generated by Activated Ras/MEK in Human Cancer Cells

Sherri L. Christian, Dong Zu, Maria Licursi, Yumiko Komatsu, Theerawat Pongnopparat, Dianne A. Codner, Kensuke Hirasawa

PLoS One. 2012; 7(9): e44267. Published online 2012 Sep 7. doi: 10.1371/journal.pone.0044267

PMCID:: PMC3436881

Abstract Article PDF–858K

Select item 89840164.

Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target

Haizhou Wang, Yabo Zhou, Yangyang Zhang, Shilin Fang, Meng Zhang, Haiou Li, Fei Xu, Lan Liu, Jing Liu, Qiu Zhao, Fan Wang

J Immunother Cancer. 2022; 10(4): e004302. Published online 2022 Apr 5. doi: 10.1136/jitc-2021-004302

PMCID:: PMC8984016

Abstract Article PDF–15M

Select item 80540255.

Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins

Wen Cui, Elisabeth Braun, Wei Wang, Jinhong Tang, Yanyan Zheng, Benjamin Slater, Na Li, Cheng Chen, Qingxiang Liu, Bin Wang, Xiu Li, Yinkai Duan, Yunjie Xiao, Ruijiao Ti, Dominik Hotter, Xiaoyun Ji, Lei Zhang, Jun Cui, Yong Xiong, Daniel Sauter, Zefang Wang, Frank Kirchhoff, Haitao Yang

Proc Natl Acad Sci U S A. 2021 Apr 13; 118(15): e2022269118. Published online 2021 Apr 5. doi: 10.1073/pnas.2022269118

PMCID:: PMC8054025

Abstract Article PDF–2.2M

Select item 56809246.

Guanylate-binding protein 2 regulates Drp1-mediated mitochondrial fission to suppress breast cancer cell invasion

Juan Zhang, Yu Zhang, Wenshuang Wu, Fang Wang, Xinyu Liu, Guanghou Shui, Chunlai Nie

Cell Death Dis. 2017 Oct; 8(10): e3151. Published online 2017 Oct 26. doi: 10.1038/cddis.2017.559

Correction in:: Cell Death Dis. 2018 Nov; 9(11): 1127.

PMCID:: PMC5680924

Abstract Article PDF–2.0M

Select item 46116357.

Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins

Arun K. Haldar, Clémence Foltz, Ryan Finethy, Anthony S. Piro, Eric M. Feeley, Danielle M. Pilla-Moffett, Masaki Komatsu, Eva-Maria Frickel, Jörn Coers

Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41): E5628–E5637. Published online 2015 Sep 28. doi: 10.1073/pnas.1515966112

PMCID:: PMC4611635

Abstract Article PDF–2.2M

Select item 35422188.

Autophagy restricts Chlamydia trachomatis growth in human macrophages via IFNG-inducible guanylate binding proteins

Munir A. Al-Zeer, Hesham M. Al-Younes, Daniel Lauster, Mohammad Abu Lubad, Thomas F. Meyer

Autophagy. 2013 Jan 1; 9(1): 50–62. doi: 10.4161/auto.22482

PMCID:: PMC3542218

Abstract Article PDF–7.1M

Select item 30425659.

Dimerization and Its Role in GMP Formation by Human Guanylate Binding Proteins

Nazish Abdullah, Meena Balakumari, Apurba Kumar Sau

Biophys J. 2010 Oct 6; 99(7): 2235–2244. doi: 10.1016/j.bpj.2010.07.025

Correction in:: Biophys J. 2011 Sep 21; 101(6): 1556.

PMCID:: PMC3042565

Abstract Article PDF–1013K

Select item 988746310.

GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling

Shujiang Ye, Siyu Li, Lei Qin, Wei Zheng, Bin Liu, Xiaohui Li, Zhenhua Ren, Huaiming Zhao, Xudong Hu, Nan Ye, Guangyuan Li

Oncol Rep. 2023 Mar; 49(3): 49. Published online 2023 Jan 20. doi: 10.3892/or.2023.8486

PMCID:: PMC9887463

Abstract Article PDF–9.8M

Select item 989851311.

Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis

Jangho Lee, Ji-Hye Song, Jae-Ho Park, Min-Yu Chung, Seung-Hyun Lee, Sae-Bom Jeon, So Hee Park, Jin-Taek Hwang, Hyo-Kyoung Choi

Exp Mol Med. 2023 Jan; 55(1): 143–157. Published online 2023 Jan 6. doi: 10.1038/s12276-022-00919-5

PMCID:: PMC9898513

Abstract Article PDF–5.7M

Select item 36136712.

Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

Y S Cheng, C E Patterson, P Staeheli

Mol Cell Biol. 1991 Sep; 11(9): 4717–4725. doi: 10.1128/mcb.11.9.4717

PMCID:: PMC361367

Summary Page Browse PDF–1.9M

Select item 299842413.

Intracellular Trafficking of Guanylate-Binding Proteins Is Regulated by Heterodimerization in a Hierarchical Manner

Nathalie Britzen-Laurent, Michael Bauer, Valeria Berton, Nicole Fischer, Adrian Syguda, Simone Reipschläger, Elisabeth Naschberger, Christian Herrmann, Michael Stürzl

PLoS One. 2010; 5(12): e14246. Published online 2010 Dec 7. doi: 10.1371/journal.pone.0014246

PMCID:: PMC2998424

Abstract Article PDF–550K

Select item 260067014.

Hepatitis C virus infection protein network

B de Chassey, V Navratil, L Tafforeau, M S Hiet, A Aublin-Gex, S Agaugué, G Meiffren, F Pradezynski, B F Faria, T Chantier, M Le Breton, J Pellet, N Davoust, P E Mangeot, A Chaboud, F Penin, Y Jacob, P O Vidalain, M Vidal, P André, C Rabourdin-Combe, V Lotteau

Mol Syst Biol. 2008; 4: 230. Published online 2008 Nov 4. doi: 10.1038/msb.2008.66

PMCID:: PMC2600670

Abstract Article PDF–2.5M

Select item 405025015.

Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood–brain barrier dysfunction

Shawna M Woollard, Biju Bhargavan, Fang Yu, Georgette D Kanmogne

J Cereb Blood Flow Metab. 2014 Jun; 34(6): 1047–1059. Published online 2014 Mar 26. doi: 10.1038/jcbfm.2014.54

PMCID:: PMC4050250

Abstract Article PDF–932K

Select item 467168316.

The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells

Thomas C. Whisenant, Eigen R. Peralta, Lauren D. Aarreberg, Nina J. Gao, Steven R. Head, Phillip Ordoukhanian, Jamie R. Williamson, Daniel R. Salomon

PLoS One. 2015; 10(12): e0144409. Published online 2015 Dec 7. doi: 10.1371/journal.pone.0144409

PMCID:: PMC4671683

Abstract Article PDF–6.2M

Select item 526093917.

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman

Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387

PMCID:: PMC5260939

Abstract Article PDF–1.1M

Select item 933831318.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 395408119.

A high-throughput approach for measuring temporal changes in the interactome

Anders R. Kristensen, Joerg Gsponer, Leonard J. Foster

Nat Methods. Author manuscript; available in PMC 2014 Mar 14.

Published in final edited form as: Nat Methods. 2012 Sep; 9(9): 907–909. Published online 2012 Aug 5. doi: 10.1038/nmeth.2131

PMCID:: PMC3954081

Abstract Article PDF–632K

Select item 1015161520.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

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