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Select item 104544981.

WSB1 Involvement in Prostate Cancer Progression

Laura Boldrini, Massimo Bardi

Genes (Basel) 2023 Aug; 14(8): 1558. Published online 2023 Jul 29. doi: 10.3390/genes14081558

PMCID:: PMC10454498

Abstract Article PDF–785K

Select item 59435352.

WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer

Flore-Anne Poujade, Aarren Mannion, Nicholas Brittain, Andrew Theodosi, Ellie Beeby, Katarzyna B. Leszczynska, Ester M. Hammond, John Greenman, Christopher Cawthorne, Isabel M. Pires

Br J Cancer. 2018 May 1; 118(9): 1229–1237. Published online 2018 Mar 15. doi: 10.1038/s41416-018-0056-3

PMCID:: PMC5943535

Abstract Article PDF–1.4M

Select item 49922163.

WSB1: from homeostasis to hypoxia

Moinul Haque, Joseph Keith Kendal, Ryan Matthew MacIsaac, Douglas James Demetrick

J Biomed Sci. 2016; 23: 61. Published online 2016 Aug 19. doi: 10.1186/s12929-016-0270-3

PMCID:: PMC4992216

Abstract Article PDF–1.5M

Select item 46475584.

WSB1 promotes tumor metastasis by inducing pVHL degradation

Jung Jin Kim, Seung Baek Lee, Jinsung Jang, Sang-Yeop Yi, Sun-Hyun Kim, Sang-Ah Han, Jong-Min Lee, Seo-Yun Tong, Nicole D. Vincelette, Bowen Gao, Ping Yin, Debra Evans, Dong Wook Choi, Bo Qin, Tongzheng Liu, Haoxing Zhang, Min Deng, Jin Jen, Jun Zhang, Liewei Wang, Zhenkun Lou

Genes Dev. 2015 Nov 1; 29(21): 2244–2257. doi: 10.1101/gad.268128.115

PMCID:: PMC4647558

Abstract Article PDF–1.9M

Select item 24234805.

The WSB1 Gene Is Involved in Pancreatic Cancer Progression

Cendrine Archange, Jonathan Nowak, Stéphane Garcia, Vincent Moutardier, Ezequiel Luis Calvo, Jean-Charles Dagorn, Juan Lucio Iovanna

PLoS One. 2008; 3(6): e2475. Published online 2008 Jun 25. doi: 10.1371/journal.pone.0002475

PMCID:: PMC2423480

Abstract Article PDF–705K

Select item 79377246.

WSB1 and IL21R Genetic Variants Are Involved in Th2 Immune Responses to Ascaris lumbricoides

Valdirene Leão Carneiro, Hugo Bernardino Ferreira da Silva, Gerson de Almeida Queiroz, Rafael Valente Veiga, Pablo Rafael Silveira Oliveira, Norma Vilany Queiroz Carneiro, Anaque de Oliveira Pires, Raimon Rios da Silva, Flavia Sena, Emilia Belitardo, Regina Nascimento, Milca Silva, Cintia Rodrigues Marques, Ryan dos Santos Costa, Neuza Maria Alcantra-Neves, Mauricio L. Barreto, Philip J. Cooper, Camila Alexandrina Figueiredo

Front Immunol. 2021; 12: 622051. Published online 2021 Feb 22. doi: 10.3389/fimmu.2021.622051

PMCID:: PMC7937724

Abstract Article PDF–1009K

Select item 111099457.

WSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination

Jie Zhang, Yuanyuan Yu, Xiuqun Zou, Yaning Du, Qiankun Liang, Mengyao Gong, Yurong He, Junqi Luo, Dandan Wu, Xiaoli Jiang, Matt Sinclair, Emad Tajkhorshid, Hong-Zhuan Chen, Zhaoyuan Hou, Yuejuan Zheng, Lin-Feng Chen, Xiao-Dong Yang

Nucleic Acids Res. 2024 May 22; 52(9): 4969–4984. Published online 2024 Mar 7. doi: 10.1093/nar/gkae161

PMCID:: PMC11109945

Abstract Article PDF–1.6M

Select item 50852268.

miR-592/WSB1/HIF-1α axis inhibits glycolytic metabolism to decrease hepatocellular carcinoma growth

Yan-Yan Jia, Jin-Yi Zhao, Bing-Ling Li, Kai Gao, Ying Song, Mei-You Liu, Xiao-Juan Yang, Yan Xue, Ai-Dong Wen, Lei Shi

Oncotarget. 2016 Jun 7; 7(23): 35257–35269. Published online 2016 May 2. doi: 10.18632/oncotarget.9135

PMCID:: PMC5085226

Abstract Article PDF–7.9M

Select item 53398509.

WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation

Jung Jin Kim, Seung Baek Lee, Sang-Yeop Yi, Sang-Ah Han, Sun-Hyun Kim, Jong-Min Lee, Seo-Yun Tong, Ping Yin, Bowen Gao, Jun Zhang, Zhenkun Lou

Cell Res. 2017 Feb; 27(2): 274–293. Published online 2016 Dec 13. doi: 10.1038/cr.2016.148

PMCID:: PMC5339850

Abstract Article PDF–7.2M

Select item 195147610.

Ubiquitination-Induced Conformational Change within the Deiodinase Dimer Is a Switch Regulating Enzyme Activity

G. D. Vivek Sagar, Balázs Gereben, Isabelle Callebaut, Jean-Paul Mornon, Anikó Zeöld, Wagner S. da Silva, Cristina Luongo, Monica Dentice, Susana M. Tente, Beatriz C. G. Freitas, John W. Harney, Ann Marie Zavacki, Antonio C. Bianco

Mol Cell Biol. 2007 Jul; 27(13): 4774–4783. Published online 2007 Apr 23. doi: 10.1128/MCB.00283-07

PMCID:: PMC1951476

Abstract Article PDF–1.0M

Select item 1007034411.

PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions

Jiayi Chen, Mei Li, Yeqing Liu, Tangming Guan, Xiao Yang, Yalei Wen, Yingjie Zhu, Zeyu Xiao, Xiangchun Shen, Haoxing Zhang, Hui Tang, Tongzheng Liu

Cell Death Differ. 2023 Apr; 30(4): 1082–1095. Published online 2023 Feb 23. doi: 10.1038/s41418-023-01128-x

PMCID:: PMC10070344

Abstract Article PDF–5.0M

Select item 907223112.

WSB1 regulates c-Myc expression through β-catenin signaling and forms a feedforward circuit

Xiaomeng Gao, Jieqiong You, Yanling Gong, Meng Yuan, Haiying Zhu, Liang Fang, Hong Zhu, Meidan Ying, Qiaojun He, Bo Yang, Ji Cao

Acta Pharm Sin B. 2022 Mar; 12(3): 1225–1239. Published online 2021 Oct 26. doi: 10.1016/j.apsb.2021.10.021

PMCID:: PMC9072231

Abstract Article PDF–2.9M

Select item 717524913.

Deubiquitylase OTUD6B Governs pVHL Stability in an Enzyme‐Independent Manner and Suppresses Hepatocellular Carcinoma Metastasis

Xinxin Liu, Xiaoli Zhang, Zhiqiang Peng, Chunnan Li, Ze Wang, Chanjuan Wang, Zhikang Deng, Bo Wu, Yu Cui, Zhanxin Wang, Chun‐Ping Cui, Min Zheng, Lingqiang Zhang

Adv Sci (Weinh) 2020 Apr; 7(8): 1902040. Published online 2020 Mar 8. doi: 10.1002/advs.201902040

PMCID:: PMC7175249

Abstract Article PDF–4.0M

Select item 489963014.

Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1

Frederick C. Nucifora, Jr, Leslie G. Nucifora, Chee-Hoe Ng, Nicolas Arbez, Yajuan Guo, Elaine Roby, Vered Shani, Simone Engelender, Dong Wei, Xiao-Fang Wang, Tianxia Li, Darren J. Moore, Olga Pletnikova, Juan C. Troncoso, Akira Sawa, Ted M. Dawson, Wanli Smith, Kah-Leong Lim, Christopher A. Ross

Nat Commun. 2016; 7: 11792. Published online 2016 Jun 7. doi: 10.1038/ncomms11792

PMCID:: PMC4899630

Abstract Article PDF–1.3M

Select item 176169415.

WSB-1 is a Hedgehog-inducible ubiquitin ligase that modulates thyroid hormone activation and PTHrP secretion in the developing growth plate.

Monica Dentice, Amitabha Bandyopadhyay, Balázs Gereben, Isabelle Callebaut, Marcelo A. Christoffolete, Brian W. Kim, Sahar Nissim, Jean-Paul Mornon, Ann Marie Zavacki, Anikó Zeöld, Luciane P. Capelo, Cyntia Curcio-Morelli, Rogério Ribeiro, John W. Harney, Clifford J. Tabin, Antonio C. Bianco

Nat Cell Biol. Author manuscript; available in PMC 2007 Jan 3.

Published in final edited form as: Nat Cell Biol. 2005 Jul; 7(7): 698–705. Published online 2005 Jun 19. doi: 10.1038/ncb1272