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Select item 105165751.

CircUBXN7 promotes macrophage infiltration and renal fibrosis associated with the IGF2BP2-dependent SP1 mRNA stability in diabetic kidney disease

Ziyue Lin, Dan Lv, Xiaohui Liao, Rui Peng, Handeng Liu, Tianhui Wu, Keqian Wu, Yan Sun, Zheng Zhang

Front Immunol. 2023; 14: 1226962. Published online 2023 Sep 6. doi: 10.3389/fimmu.2023.1226962

PMCID:: PMC10516575

Abstract Article PDF–9.9M

Select item 96763962.

HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication

Sen Yuan, Jiaqi Xu, Min Wang, Junsong Huang, Shuangshuang Ma, Yang Liu, Yujia Ke, Xianhuang Zeng, Kangwei Wu, Jingwen Wang, Xuezhang Tian, Dandan Zheng, Tanzeel Yousaf, Wajeeha Naz, Junwei Sun, Lang Chen, Deyin Guo, Mingxiong Guo, Guihong Sun

Cell Mol Gastroenterol Hepatol. 2023; 15(1): 179–195. Published online 2022 Sep 9. doi: 10.1016/j.jcmgh.2022.09.003

PMCID:: PMC9676396

Abstract Article PDF–5.0M

Select item 78820253.

UBXN7 cofactor of CRL3^KEAP1 and CRL2^VHL ubiquitin ligase complexes mediates reciprocal regulation of NRF2 and HIF-1α proteins

Jacopo Di Gregorio, Lucia Cilenti, Camilla T. Ambivero, Thomas Andl, Ronglih Liao, Antonis S. Zervos

Biochim Biophys Acta Mol Cell Res. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Res. 2021 Jan 12; 1868(4): 118963. Published online 2021 Jan 12. doi: 10.1016/j.bbamcr.2021.118963

PMCID:: PMC7882025

Abstract Article PDF–1.8M

Select item 78497774.

Spironolactone-induced XPB degradation requires TFIIH integrity and ubiquitin-selective segregase VCP/p97

Anil K. Chauhan, Ping Li, Yingming Sun, Gulzar Wani, Qianzheng Zhu, Altaf A. Wani

Cell Cycle. 2021; 20(1): 81–95. Published online 2020 Dec 31. doi: 10.1080/15384101.2020.1860559

PMCID:: PMC7849777

Abstract Article PDF–2.0M

Select item 69944965.

Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein

Lucia Cilenti, Jacopo Di Gregorio, Camilla T. Ambivero, Thomas Andl, Ronglih Liao, Antonis S. Zervos

Sci Rep. 2020; 10: 1609. Published online 2020 Jan 31. doi: 10.1038/s41598-020-58484-8

PMCID:: PMC6994496

Abstract Article PDF–3.5M

Select item 48171716.

Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome Group B (CSB) in Damaged Chromatin

Jinshan He, Qianzheng Zhu, Gulzar Wani, Nidhi Sharma, Altaf A. Wani

J Biol Chem. 2016 Apr 1; 291(14): 7396–7408. Published online 2016 Jan 29. doi: 10.1074/jbc.M115.705350

PMCID:: PMC4817171

Abstract Article PDF–3.1M

Select item 96337897.

Cooperative assembly of p97 complexes involved in replication termination

Olga V. Kochenova, Sirisha Mukkavalli, Malavika Raman, Johannes C. Walter

Nat Commun. 2022; 13: 6591. Published online 2022 Nov 3. doi: 10.1038/s41467-022-34210-y

PMCID:: PMC9633789

Abstract Article PDF–2.1M

Select item 33495488.

UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation

Susanne Bandau, Axel Knebel, Zoe O Gage, Nicola T Wood, Gabriela Alexandru

BMC Biol. 2012; 10: 36. Published online 2012 Apr 26. doi: 10.1186/1741-7007-10-36

PMCID:: PMC3349548

Abstract Article PDF–10M

Select item 90984619.

Active conformation of the p97-p47 unfoldase complex

Yang Xu, Han Han, Ian Cooney, Yuxuan Guo, Noah G. Moran, Nathan R. Zuniga, John C. Price, Christopher P. Hill, Peter S. Shen

Nat Commun. 2022; 13: 2640. Published online 2022 May 12. doi: 10.1038/s41467-022-30318-3

PMCID:: PMC9098461

Abstract Article PDF–1.7M

Select item 381746310.

TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes

Ian R Kelsall, David M Duda, Jennifer L Olszewski, Kay Hofmann, Axel Knebel, Frédéric Langevin, Nicola Wood, Melanie Wightman, Brenda A Schulman, Arno F Alpi

EMBO J. 2013 Oct 30; 32(21): 2848–2860. Published online 2013 Sep 27. doi: 10.1038/emboj.2013.209

PMCID:: PMC3817463

Abstract Article PDF–1.2M

Select item 334843211.

NEDD8 links Cullin–Ring ubiquitin Ligase function to the p97 pathway

Willem den Besten, Rati Verma, Gary Kleiger, Robert S. Oania, Raymond J. Deshaies

Nat Struct Mol Biol. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: Nat Struct Mol Biol. 2012 May; 19(5): 511–S1. Published online 2012 Apr 1. doi: 10.1038/nsmb.2269

PMCID:: PMC3348432

Abstract Article PDF–1.2M

Select item 571014412.

A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation

Marc A.J. Morgan, Ryan A. Rickels, Clayton K. Collings, Xiaolin He, Kaixiang Cao, Hans-Martin Herz, Kira A. Cozzolino, Nebiyu A. Abshiru, Stacy A. Marshall, Emily J. Rendleman, Christie C. Sze, Andrea Piunti, Neil L. Kelleher, Jeffrey N. Savas, Ali Shilatifard

Genes Dev. 2017 Oct 1; 31(19): 2003–2014. doi: 10.1101/gad.305201.117

PMCID:: PMC5710144

Abstract Article PDF–5.1M

Select item 694204513.

Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne

Xiao Wu, Shichang Liu, Cari Sagum, Jianji Chen, Rajesh Singh, Apurva Chaturvedi, John R. Horton, Tanuja R. Kashyap, David Fushman, Xiaodong Cheng, Mark T. Bedford, Bin Wang

Genes Dev. 2019 Dec 1; 33(23-24): 1702–1717. doi: 10.1101/gad.332395.119

PMCID:: PMC6942045

Abstract Article PDF–7.6M

Select item 740226614.

APC/C-dependent control of gene expression and cell identity

Eugene Oh, Kevin G. Mark, Annamaria Mocciaro, Edmond R. Watson, J. Rajan Prabu, Denny D. Cha, Martin Kampmann, Nathan Gamarra, Coral Y. Zhou, Michael Rape

Nature. Author manuscript; available in PMC 2020 Aug 19.

Published in final edited form as: Nature. 2020 Mar; 579(7797): 136–140. Published online 2020 Feb 19. doi: 10.1038/s41586-020-2034-1

PMCID:: PMC7402266

Abstract Article PDF–5.3M

Select item 261466315.

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

Gabriela Alexandru, Johannes Graumann, Geoffrey T. Smith, Natalie J. Kolawa, Ruihua Fang, Raymond J. Deshaies

Cell. Author manuscript; available in PMC 2009 Mar 5.

Published in final edited form as: Cell. 2008 Sep 5; 134(5): 804–816. doi: 10.1016/j.cell.2008.06.048

PMCID:: PMC2614663

Abstract Article PDF–3.7M

Select item 603073016.

AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation

Julia Hülsmann, Bojana Kravic, Matthias Weith, Matthias Gstaiger, Ruedi Aebersold, Ben C. Collins, Hemmo Meyer

Mol Cell Proteomics. 2018 Jul; 17(7): 1295–1307. Published online 2018 Mar 29. doi: 10.1074/mcp.RA117.000471

PMCID:: PMC6030730

Abstract Article PDF–3.8M

Select item 428236917.

The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines

Nikolaos Charlaftis, Tesha Suddason, Xuefeng Wu, Saba Anwar, Michael Karin, Ewen Gallagher

EMBO J. 2014 Nov 3; 33(21): 2581–2596. Published online 2014 Sep 26. doi: 10.15252/embj.201488351

PMCID:: PMC4282369

Abstract Article PDF–3.0M

Select item 1008090818.

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy

BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4

PMCID:: PMC10080908

Abstract Article PDF–3.2M

Select item 729557619.

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137

Fengwen Zhang, Paul D Bieniasz

eLife. 2020; 9: e55806. Published online 2020 Jun 15. doi: 10.7554/eLife.55806

PMCID:: PMC7295576

Abstract Article PDF–4.3M

Select item 676993020.

Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners

Eunate Gallardo-Vara, Lidia Ruiz-Llorente, Juan Casado-Vela, María J. Ruiz-Rodríguez, Natalia López-Andrés, Asit K. Pattnaik, Miguel Quintanilla, Carmelo Bernabeu

Cells. 2019 Sep; 8(9): 1082. Published online 2019 Sep 13. doi: 10.3390/cells8091082

PMCID:: PMC6769930

Abstract Article PDF–4.3M

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PMC Links for Gene (Select 26043) (51)
PMC
PREDICTED: Homo sapiens p21 (RAC1) activated kinase 2 (PAK2), transcript variant...
PREDICTED: Homo sapiens p21 (RAC1) activated kinase 2 (PAK2), transcript variant X3, mRNA
gi|2462590105|ref|XM_054346671.1|

Nucleotide
PREDICTED: Homo sapiens TATA-box binding protein associated factor 6 (TAF6), tra...
PREDICTED: Homo sapiens TATA-box binding protein associated factor 6 (TAF6), transcript variant X5, mRNA
gi|2217368332|ref|XM_024446899.2|

Nucleotide
PREDICTED: Equus caballus cartilage acidic protein 1 (CRTAC1), transcript varian...
PREDICTED: Equus caballus cartilage acidic protein 1 (CRTAC1), transcript variant X3, mRNA
gi|1333546494|ref|XM_005602321.3|

Nucleotide

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