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Select item 104080631.

Prognostic and biological function value of OSBPL3 in colorectal cancer analyzed by multi-omic data analysis

Chengxing Wang, Yaoming He, Yu He, Weijun Liang, Chaorong Zhou, Meimei Wu, Zijie Meng, Wanglin Li, Jie Cao

BMC Gastroenterol. 2023; 23: 270. Published online 2023 Aug 7. doi: 10.1186/s12876-023-02824-1

PMCID:: PMC10408063

Abstract Article PDF–5.6M

Select item 84789562.

Oxysterol binding protein-like 3 (OSBPL3) is a novel driver gene that promotes tumor growth in part through R-Ras/Akt signaling in gastric cancer

Qingjiang Hu, Takaaki Masuda, Kensuke Koike, Kuniaki Sato, Taro Tobo, Shotaro Kuramitsu, Akihiro Kitagawa, Atsushi Fujii, Miwa Noda, Yusuke Tsuruda, Hajime Otsu, Yosuke Kuroda, Shuhei Ito, Eiji Oki, Koshi Mimori

Sci Rep. 2021; 11: 19178. Published online 2021 Sep 28. doi: 10.1038/s41598-021-98485-9

PMCID:: PMC8478956

Abstract Article PDF–5.4M

Select item 80492863.

Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins

Junsen Tong, Lingchen Tan, Young Jun Im

PLoS One. 2021; 16(4): e0248781. Published online 2021 Apr 15. doi: 10.1371/journal.pone.0248781

PMCID:: PMC8049286

Abstract Article PDF–2.5M

Select item 74606214.

Downregulation of ORP3 Correlates with Reduced Survival of Colon Cancer Patients with Advanced Nodal Metastasis and of Female Patients with Grade 3 Colon Cancer

Pengfei Xu, Julia Richter, Annette Blatz, Fabian Gärtner, Roland Alberts, Anca Azoitei, Wycliffe Arika Makori, Sabine Meessen, Uwe Knippschild, Cagatay Günes

Int J Mol Sci. 2020 Aug; 21(16): 5894. Published online 2020 Aug 16. doi: 10.3390/ijms21165894

PMCID:: PMC7460621

Abstract Article PDF–2.4M

Select item 105168065.

Loss of ORP3 induces aneuploidy and promotes bladder cancer cell invasion through deregulated microtubule and actin dynamics

Xue Wang, Junnan Liu, Anca Azoitei, Tim Eiseler, Sabine Meessen, Wencheng Jiang, Xi Zheng, Arika W. Makori, Markus Eckstein, Arndt Hartmann, Stephan Stilgenbauer, Mohamed Elati, Meike Hohwieler, Alexander Kleger, Axel John, Friedemann Zengerling, Felix Wezel, Christian Bolenz, Cagatay Günes

Cell Mol Life Sci. 2023 Oct; 80(10): 299. Published online 2023 Sep 22. doi: 10.1007/s00018-023-04959-6

PMCID:: PMC10516806

Abstract Article PDF–4.5M

Select item 71599236.

Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex

Ryan S D'Souza, Jun Y Lim, Alper Turgut, Kelly Servage, Junmei Zhang, Kim Orth, Nisha G Sosale, Matthew J Lazzara, Jeremy Allegood, James E Casanova

eLife. 2020; 9: e54113. Published online 2020 Apr 1. doi: 10.7554/eLife.54113

PMCID:: PMC7159923

Abstract Article PDF–7.4M

Select item 61309447.

VAMP-associated protein-A and oxysterol-binding protein–related protein 3 promote the entry of late endosomes into the nucleoplasmic reticulum

Mark F. Santos, Germana Rappa, Jana Karbanová, Thomas Kurth, Denis Corbeil, Aurelio Lorico

J Biol Chem. 2018 Sep 7; 293(36): 13834–13848. Published online 2018 Jul 17. doi: 10.1074/jbc.RA118.003725

PMCID:: PMC6130944

Abstract Article PDF–3.5M

Select item 97532588.

The relationships of OSBPL3 expression with KI-67 expression and KRAS mutations in CRC: implications for diagnosis and prognosis

Min Zhang, Lei Meng, Zhaoxuan Zhang, Jing Wu, Xi Chen, Yuejing Wang, Jie He

BMC Med Genomics. 2022; 15: 259. Published online 2022 Dec 14. doi: 10.1186/s12920-022-01402-w

PMCID:: PMC9753258

Abstract Article PDF–2.7M

Select item 34486489.

You Zhou, Marius R. Robciuc, Martin Wabitsch, Anne Juuti, Marja Leivonen, Christian Ehnholm, Hannele Yki-Järvinen, Vesa M. Olkkonen

PLoS One. 2012; 7(9): e45352. Published online 2012 Sep 21. doi: 10.1371/journal.pone.0045352

PMCID:: PMC3448648

Abstract Article PDF–2.0M

Select item 226729310.

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket

Monika Suchanek, Riikka Hynynen, Gerd Wohlfahrt, Markku Lehto, Marie Johansson, Hannu Saarinen, Anna Radzikowska, Christoph Thiele, Vesa M. Olkkonen

Biochem J. 2007 Aug 1; 405(Pt 3): 473–480. Prepublished online 2007 Apr 11. Published online 2007 Jul 13. doi: 10.1042/BJ20070176

PMCID:: PMC2267293

Abstract Article PDF–535K

Select item 574639811.

Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity

Maria Oikonomaki, Pierre Bady, Monika E. Hegi

Oncotarget. 2017 Dec 15; 8(66): 110490–110502. Published online 2017 Nov 30. doi: 10.18632/oncotarget.22798

PMCID:: PMC5746398

Abstract Article PDF–4.2M

Select item 406815812.

VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase

Yorann Baron, Patrick G Pedrioli, Kshitiz Tyagi, Clare Johnson, Nicola T Wood, Daniel Fountaine, Melanie Wightman, Gabriela Alexandru

BMC Biol. 2014; 12: 39. Published online 2014 May 29. doi: 10.1186/1741-7007-12-39

PMCID:: PMC4068158

Abstract Article PDF–2.8M

Select item 389378313.

Identification of proteins that interact with alpha A-crystallin using a human proteome microarray

Qi Fan, Lv-Zhen Huang, Xiang-Jia Zhu, Ke-Ke Zhang, Hong-Fei Ye, Yi Luo, Xing-Huai Sun, Peng Zhou, Yi Lu

Mol Vis. 2014; 20: 117–124. Published online 2014 Jan 14.

PMCID:: PMC3893783

Abstract Article PDF–1024K

Select item 720220914.

Regulation of epidermal differentiation through KDF1‐mediated deubiquitination of IKKα

Yuanyuan Li, Liangfeng Tang, Jiping Yue, Xuewen Gou, Anning Lin, Scott D Weatherbee, Xiaoyang Wu

EMBO Rep. 2020 May 6; 21(5): e48566. Published online 2020 Apr 1. doi: 10.15252/embr.201948566

PMCID:: PMC7202209

Abstract Article PDF–6.2M

Select item 761053515.

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase

Bikash Adhikari, Jelena Bozilovic, Mathias Diebold, Jessica Denise Schwarz, Julia Hofstetter, Martin Schröder, Marek Wanior, Ashwin Narain, Markus Vogt, Nevenka Dudvarski Stankovic, Apoorva Baluapuri, Lars Schönemann, Lorenz Eing, Pranjali Bhandare, Bernhard Kuster, Andreas Schlosser, Stephanie Heinzlmeir, Christoph Sotriffer, Stefan Knapp, Elmar Wolf

Nat Chem Biol. Author manuscript; available in PMC 2021 Apr 6.

Published in final edited form as: Nat Chem Biol. 2020 Nov 1; 16(11): 1179–1188. Published online 2020 Sep 28. doi: 10.1038/s41589-020-00652-y

PMCID:: PMC7610535

Abstract Article PDF–5.1M

Select item 262894616.

Global analysis of host-pathogen interactions that regulate early stage HIV-1 replication

Renate König, Yingyao Zhou, Daniel Elleder, Tracy L. Diamond, Ghislain M.C. Bonamy, Jeffrey T. Irelan, Chih-yuan Chiang, Buu P. Tu, Paul D. De Jesus, Caroline E. Lilley, Shannon Seidel, Amanda M. Opaluch, Jeremy S. Caldwell, Matthew D. Weitzman, Kelli L. Kuhen, Sourav Bandyopadhyay, Trey Ideker, Anthony P. Orth, Loren J. Miraglia, Frederic D. Bushman, John A. Young, Sumit K. Chanda

Cell. Author manuscript; available in PMC 2009 Oct 3.

Published in final edited form as: Cell. 2008 Oct 3; 135(1): 49–60. doi: 10.1016/j.cell.2008.07.032

PMCID:: PMC2628946

Abstract Article PDF–3.4M

Select item 331091117.

Global landscape of HIV–human protein complexes

Stefanie Jäger, Peter Cimermancic, Natali Gulbahce, Jeffrey R. Johnson, Kathryn E. McGovern, Starlynn C. Clarke, Michael Shales, Gaelle Mercenne, Lars Pache, Kathy Li, Hilda Hernandez, Gwendolyn M. Jang, Shoshannah L. Roth, Eyal Akiva, John Marlett, Melanie Stephens, Ivan D’Orso, Jason Fernandes, Marie Fahey, Cathal Mahon, Anthony J. O’Donoghue, Aleksandar Todorovic, John H. Morris, David A. Maltby, Tom Alber, Gerard Cagney, Frederic D. Bushman, John A. Young, Sumit K. Chanda, Wesley I. Sundquist, Tanja Kortemme, Ryan D. Hernandez, Charles S. Craik, Alma Burlingame, Andrej Sali, Alan D. Frankel, Nevan J. Krogan

Nature. Author manuscript; available in PMC 2013 Jan 19.

Published in final edited form as: Nature. 2011 Dec 21; 481(7381): 365–370. Published online 2011 Dec 21. doi: 10.1038/nature10719

PMCID:: PMC3310911

Abstract Article PDF–1.8M

Select item 655126618.

FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane

Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri

Structure. Author manuscript; available in PMC 2020 Jun 4.

Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022

PMCID:: PMC6551266

Abstract Article PDF–3.4M

Select item 288296119.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Abstract Article PDF–1.2M

Select item 430501520.

Global mapping of herpesvirus-host protein complexes reveals a novel transcription strategy for late genes

Zoe H. Davis, Erik Verschueren, Gwendolyn M. Jang, Kevin Kleffman, Jeffrey R. Johnson, Jimin Park, John Von Dollen, M. Cyrus Maher, Tasha Johnson, William Newton, Stefanie Jäger, Michael Shales, Julie Horner, Ryan D. Hernandez, Nevan J. Krogan, Britt A. Glaunsinger

Mol Cell. Author manuscript; available in PMC 2016 Jan 22.

Published in final edited form as: Mol Cell. 2015 Jan 22; 57(2): 349–360. Published online 2014 Dec 24. doi: 10.1016/j.molcel.2014.11.026

PMCID:: PMC4305015

Abstract Article PDF–1.9M

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