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Select item 88099351.

HIG1 domain family member 1A disrupts proliferation, migration, and invasion of colon adenocarcinoma cells

Zhenyu Xu, Junjie Sun, Yong Mao, Yang Chen, Ting Zhang, Yan Qin, Dong Hua

Bioengineered. 2021; 12(2): 10501–10511. Published online 2021 Dec 29. doi: 10.1080/21655979.2021.1999368

PMCID:: PMC8809935

Abstract Article PDF–3.3M

Select item 43212852.

Higd1a is a positive regulator of cytochrome c oxidase

Takaharu Hayashi, Yoshihiro Asano, Yasunori Shintani, Hiroshi Aoyama, Hidetaka Kioka, Osamu Tsukamoto, Masahide Hikita, Kyoko Shinzawa-Itoh, Kazuaki Takafuji, Shuichiro Higo, Hisakazu Kato, Satoru Yamazaki, Ken Matsuoka, Atsushi Nakano, Hiroshi Asanuma, Masanori Asakura, Tetsuo Minamino, Yu-ichi Goto, Takashi Ogura, Masafumi Kitakaze, Issei Komuro, Yasushi Sakata, Tomitake Tsukihara, Shinya Yoshikawa, Seiji Takashima

Proc Natl Acad Sci U S A. 2015 Feb 3; 112(5): 1553–1558. Published online 2015 Jan 20. doi: 10.1073/pnas.1419767112

PMCID:: PMC4321285

Abstract Article PDF–1.0M

Select item 64760723.

Higd1a Protects Cells from Lipotoxicity under High-Fat Exposure

Tong Li, Wen-jing Xian, Yang Gao, Shuai Jiang, Qi-hong Yu, Qi-chang Zheng, Yong Zhang

Oxid Med Cell Longev. 2019; 2019: 6051262. Published online 2019 Apr 8. doi: 10.1155/2019/6051262

PMCID:: PMC6476072

Abstract Article PDF–9.6M

Select item 44573794.

Drug screening strategy for human membrane proteins: from NMR protein backbone structure to in silica- and NMR-screened hits

Steffen Lindert, Innokentiy Maslennikov, Ellis Chiu, Levi C Pierce, J. Andrew McCammon, Senyon Choe

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Jun 5.

Published in final edited form as: Biochem Biophys Res Commun. 2014 Mar 21; 445(4): 724–733. Published online 2014 Feb 10. doi: 10.1016/j.bbrc.2014.01.179

PMCID:: PMC4457379

Abstract Article PDF–638K

Select item 37408885.

Higd-1a interacts with Opa1 and is required for the morphological and functional integrity of mitochondria

Hyun-Jung An, Geunyoung Cho, Jie-Oh Lee, Sang-Gi Paik, Young Sang Kim, Hayyoung Lee

Proc Natl Acad Sci U S A. 2013 Aug 6; 110(32): 13014–13019. Published online 2013 Jul 22. doi: 10.1073/pnas.1307170110

PMCID:: PMC3740888

Abstract Article PDF–1.1M

Select item 36399846.

Nuclear Localization of the Mitochondrial Factor HIGD1A during Metabolic Stress

Kurosh Ameri, Anthony M. Rajah, Vien Nguyen, Timothy A. Sanders, Arman Jahangiri, Michael DeLay, Matthew Donne, Hwa J. Choi, Kathryn V. Tormos, Yerem Yeghiazarians, Stefanie S. Jeffrey, Paolo F. Rinaudo, David H. Rowitch, Manish Aghi, Emin Maltepe

PLoS One. 2013; 8(4): e62758. Published online 2013 Apr 30. doi: 10.1371/journal.pone.0062758

PMCID:: PMC3639984

Abstract Article PDF–5.5M

Select item 74824337.

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

Michael L. van de Weijer, Logesvaran Krshnan, Sabrina Liberatori, Elena Navarro Guerrero, Jacob Robson-Tull, Lilli Hahn, Robert Jan Lebbink, Emmanuel J.H.J. Wiertz, Roman Fischer, Daniel Ebner, Pedro Carvalho

Mol Cell. 2020 Sep 3; 79(5): 768–781.e7. doi: 10.1016/j.molcel.2020.07.009

Correction in:: Mol Cell. 2020 Oct 15; 80(2): 374–375.

PMCID:: PMC7482433

Abstract Article

Select item 41555088.

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles

Jacqueline I Goldstein, L Fredrik Jarskog, Chris Hilliard, Ana Alfirevic, Laramie Duncan, Denis Fourches, Hailiang Huang, Monkol Lek, Benjamin M Neale, Stephan Ripke, Kevin Shianna, Jin P Szatkiewicz, Alexander Tropsha, Edwin JCG van den Oord, Ingolf Cascorbi, Michael Dettling, Ephraim Gazit, Donald C Goff, Arthur L Holden, Deanna L Kelly, Anil K Malhotra, Jimmi Nielsen, Munir Pirmohamed, Dan Rujescu, Thomas Werge, Deborah L Levy, Richard C Josiassen, James L Kennedy, Jeffrey A Lieberman, Mark J Daly, Patrick F Sullivan

Nat Commun. Author manuscript; available in PMC 2015 Mar 4.

Published in final edited form as: Nat Commun. 2014; 5: 4757. Published online 2014 Sep 4. doi: 10.1038/ncomms5757

PMCID:: PMC4155508

Abstract Article PDF–1.8M

Select item 55898009.

SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms

Carissa Pilling, Jonathan A. Cooper

Sci Rep. 2017; 7: 10838. Published online 2017 Sep 7. doi: 10.1038/s41598-017-11040-3

PMCID:: PMC5589800

Abstract Article PDF–5.5M

Select item 748475910.

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage

Marie-Christine Albert, Kerstin Brinkmann, Wojciech Pokrzywa, Saskia Diana Günther, Martin Krönke, Thorsten Hoppe, Hamid Kashkar

Cell Death Dis. 2020 Sep; 11(9): 740. Published online 2020 Sep 10. doi: 10.1038/s41419-020-02923-x

PMCID:: PMC7484759

Abstract Article PDF–2.6M

Select item 593507411.

Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches

Nathan Zuzow, Arit Ghosh, Marilyn Leonard, Jeffrey Liao, Bing Yang, Eric J. Bennett

Mol Biol Cell. 2018 May 15; 29(10): 1258–1269. doi: 10.1091/mbc.E17-12-0714

PMCID:: PMC5935074

Abstract Article PDF–5.9M

Select item 603071912.

CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement

Tina Beyer, Sylvia Bolz, Katrin Junger, Nicola Horn, Muhammad Moniruzzaman, Yasmin Wissinger, Marius Ueffing, Karsten Boldt

Mol Cell Proteomics. 2018 Jul; 17(7): 1285–1294. Published online 2018 Apr 3. doi: 10.1074/mcp.RA117.000487

PMCID:: PMC6030719

Abstract Article PDF–2.7M

Select item 584026613.

Insights into the ubiquitin-proteasome system of human embryonic stem cells

Isabel Saez, Seda Koyuncu, Ricardo Gutierrez-Garcia, Christoph Dieterich, David Vilchez

Sci Rep. 2018; 8: 4092. Published online 2018 Mar 6. doi: 10.1038/s41598-018-22384-9

PMCID:: PMC5840266

Abstract Article PDF–2.9M

Select item 31093414.

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells

Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen

Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200

PMCID:: PMC310934

Abstract Article PDF–1.3M

Select item 810809315.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 108373216.

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing

Jeremy C. Simpson, Ruth Wellenreuther, Annemarie Poustka, Rainer Pepperkok, Stefan Wiemann

EMBO Rep. 2000 Sep 15; 1(3): 287–292. doi: 10.1093/embo-reports/kvd058

PMCID:: PMC1083732

Abstract Article PDF–375K

Select item 1061767317.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 660091518.

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert

Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116

Correction in:: Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.

PMCID:: PMC6600915

Abstract Article PDF–1.7M

Select item 622622519.

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation

Jaewoo Choi, Anita Saraf, Laurence Florens, Michael P. Washburn, Luca Busino

Cell Cycle. 2018; 17(18): 2243–2255. Published online 2018 Sep 25. doi: 10.1080/15384101.2018.1522912

PMCID:: PMC6226225

Abstract Article PDF–1.7M

Select item 134750120.

The LIFEdb database in 2006

Alexander Mehrle, Heiko Rosenfelder, Ingo Schupp, Coral del Val, Dorit Arlt, Florian Hahne, Stephanie Bechtel, Jeremy Simpson, Oliver Hofmann, Winston Hide, Karl-Heinz Glatting, Wolfgang Huber, Rainer Pepperkok, Annemarie Poustka, Stefan Wiemann

Nucleic Acids Res. 2006 Jan 1; 34(Database issue): D415–D418. Published online 2005 Dec 28. doi: 10.1093/nar/gkj139

PMCID:: PMC1347501

Abstract Article PDF–301K

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