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Select item 56698141.

Assembly and Function of Heterotypic Ubiquitin Chains in Cell Cycle and Protein Quality Control

Richard G. Yau, Kerstin Doerner, Erick R. Castellanos, Diane L. Haakonsen, Achim Werner, Nan Wang, X. William Yang, Nadia Martinez-Martin, Marissa L. Matsumoto, Vishva M. Dixit, Michael Rape

Cell. Author manuscript; available in PMC 2018 Nov 2.

Published in final edited form as: Cell. 2017 Nov 2; 171(4): 918–933.e20. Published online 2017 Oct 12. doi: 10.1016/j.cell.2017.09.040

PMCID:: PMC5669814

Abstract Article PDF–3.1M

Select item 30337042.

Lesson from the Stoichiometry Determination of the Cohesin Complex: A Short Protease Mediated Elution Increases the Recovery from Cross-Linked Antibody-Conjugated Beads

Johann Holzmann, Johannes Fuchs, Peter Pichler, Jan-Michael Peters, Karl Mechtler

J Proteome Res. 2011 Feb 4; 10(2): 780–789. Published online 2010 Nov 3. doi: 10.1021/pr100927x

PMCID:: PMC3033704

Abstract Article PDF–2.5M

Select item 46080483.

Atomic structure of the APC/C and its mechanism of protein ubiquitination

Leifu Chang, Ziguo Zhang, Jing Yang, Stephen H. McLaughlin, David Barford

Nature. Author manuscript; available in PMC 2015 Dec 25.

Published in final edited form as: Nature. 2015 Jun 25; 522(7557): 450–454. Published online 2015 Jun 15. doi: 10.1038/nature14471

PMCID:: PMC4608048

Abstract Article PDF–5.4M

Select item 48786694.

Molecular mechanism of APC/C activation by mitotic phosphorylation

Suyang Zhang, Leifu Chang, Claudio Alfieri, Ziguo Zhang, Jing Yang, Sarah Maslen, Mark Skehel, David Barford

Nature. Author manuscript; available in PMC 2016 Oct 27.

Published in final edited form as: Nature. 2016 May 12; 533(7602): 260–264. Published online 2016 Apr 27. doi: 10.1038/nature17973

PMCID:: PMC4878669

Abstract Article PDF–5.3M

Select item 44566605.

Molecular architecture and mechanism of the anaphase-promoting complex

Lei-Fu Chang, Ziguo Zhang, Jing Yang, Stephen H. McLaughlin, David Barford

Nature. Author manuscript; available in PMC 2015 Jun 5.

Published in final edited form as: Nature. 2014 Sep 18; 513(7518): 388–393. Published online 2014 Jul 20. doi: 10.1038/nature13543

PMCID:: PMC4456660

Abstract Article PDF–4.7M

Select item 44443696.

Structure of an APC3-APC16 complex: Insights into assembly of the Anaphase Promoting Complex/Cyclosome

Masaya Yamaguchi, Shanshan Yu, Renping Qiao, Florian Weissmann, Darcie J. Miller, Ryan VanderLinden, Nicholas G. Brown, Jeremiah J. Frye, Jan-Michael Peters, Brenda A. Schulman

J Mol Biol. Author manuscript; available in PMC 2016 Apr 24.

Published in final edited form as: J Mol Biol. 2015 Apr 24; 427(8): 1748–1764. Published online 2014 Dec 6. doi: 10.1016/j.jmb.2014.11.020

PMCID:: PMC4444369

Abstract Article PDF–2.5M

Select item 29558087.

Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study

JESSICA J. LEE, JONAH B. ESSERS, SUBRA KUGATHASAN, JOHANNA C. ESCHER, GUILLAUME LETTRE, JOHANNAH L. BUTLER, MICHAEL C. STEPHENS, MARCO F. RAMONI, RICHARD J. GRAND, JOEL HIRSCHHORN

Ann Hum Genet. Author manuscript; available in PMC 2011 Nov 1.

Published in final edited form as: Ann Hum Genet. 2010 Nov; 74(6): 489–497. Published online 2010 Sep 15. doi: 10.1111/j.1469-1809.2010.00606.x

PMCID:: PMC2955808

Abstract Article PDF–332K

Select item 26812218.

Genome-wide association analysis identifies 20 loci that influence adult height

Michael N Weedon, Hana Lango, Cecilia M Lindgren, Chris Wallace, David M Evans, Massimo Mangino, Rachel M Freathy, John R B Perry, Suzanne Stevens, Alistair S Hall, Nilesh J Samani, Beverly Shields, Inga Prokopenko, Martin Farrall, Anna Dominiczak, Diabetes Genetics Initiative, The Wellcome Trust Case Control Consortium, Toby Johnson, Sven Bergmann, Jacques S Beckmann, Peter Vollenweider, Dawn M Waterworth, Vincent Mooser, Colin N A Palmer, Andrew D Morris, Willem H Ouwehand, Cambridge GEM Consortium, Mark Caulfield, Patricia B Munroe, Andrew T Hattersley, Mark I McCarthy, Timothy M Frayling, Jing Hua Zhao, Shengxu Li, Ruth J F Loos, Inês Barroso, Panagiotis Deloukas, Manjinder S Sandhu, Eleanor Wheeler, Nicole Soranzo, Michael Inouye, Nicholas J Wareham

Nat Genet. Author manuscript; available in PMC 2009 May 13.

Published in final edited form as: Nat Genet. 2008 May; 40(5): 575–583. Published online 2008 Apr 6. doi: 10.1038/ng.121

PMCID:: PMC2681221

Abstract Article PDF–800K

Select item 3816699.

Swm1/Apc13 Is an Evolutionarily Conserved Subunit of the Anaphase-Promoting Complex Stabilizing the Association of Cdc16 and Cdc27

Martin Schwickart, Jan Havlis, Bianca Habermann, Aliona Bogdanova, Alain Camasses, Tobias Oelschlaegel, Andrej Shevchenko, Wolfgang Zachariae

Mol Cell Biol. 2004 Apr; 24(8): 3562–3576. doi: 10.1128/MCB.24.8.3562-3576.2004

PMCID:: PMC381669

Abstract Article PDF–1.1M

Select item 269618910.

Mechanism of Ubiquitin-Chain Formation by the human Anaphase-Promoting Complex

Lingyan Jin, Adam Williamson, Sudeep Banerjee, Isabelle Philipp, Michael Rape

Cell. Author manuscript; available in PMC 2009 Jun 15.

Published in final edited form as: Cell. 2008 May 16; 133(4): 653–665. doi: 10.1016/j.cell.2008.04.012

PMCID:: PMC2696189

Abstract Article PDF–3.3M

Select item 585677511.

SUMO targets the APC/C to regulate transition from metaphase to anaphase

Karolin Eifler, Sabine A. G. Cuijpers, Edwin Willemstein, Jonne A. Raaijmakers, Dris El Atmioui, Huib Ovaa, René H. Medema, Alfred C. O. Vertegaal

Nat Commun. 2018; 9: 1119. Published online 2018 Mar 16. doi: 10.1038/s41467-018-03486-4

PMCID:: PMC5856775

Abstract Article PDF–1.8M

Select item 740226612.

APC/C-dependent control of gene expression and cell identity

Eugene Oh, Kevin G. Mark, Annamaria Mocciaro, Edmond R. Watson, J. Rajan Prabu, Denny D. Cha, Martin Kampmann, Nathan Gamarra, Coral Y. Zhou, Michael Rape

Nature. Author manuscript; available in PMC 2020 Aug 19.

Published in final edited form as: Nature. 2020 Mar; 579(7797): 136–140. Published online 2020 Feb 19. doi: 10.1038/s41586-020-2034-1

PMCID:: PMC7402266

Abstract Article PDF–5.3M

Select item 289479013.

The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature

Jianhua Zhao, Mingyao Li, Jonathan P Bradfield, Haitao Zhang, Frank D Mentch, Kai Wang, Patrick M Sleiman, Cecilia E Kim, Joseph T Glessner, Cuiping Hou, Brendan J Keating, Kelly A Thomas, Maria L Garris, Sandra Deliard, Edward C Frackelton, F George Otieno, Rosetta M Chiavacci, Robert I Berkowitz, Hakon Hakonarson, Struan FA Grant

BMC Med Genet. 2010; 11: 96. Published online 2010 Jun 14. doi: 10.1186/1471-2350-11-96

PMCID:: PMC2894790

Abstract Article PDF–803K

Select item 6498814.

Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver

Xiang-Ru Xu, Jian Huang, Zhi-Gang Xu, Bin-Zhi Qian, Zhi-Dong Zhu, Qing Yan, Ting Cai, Xin Zhang, Hua-Sheng Xiao, Jian Qu, Feng Liu, Qiu-Hua Huang, Zhi-Hong Cheng, Neng-Gan Li, Jian-Jun Du, Wei Hu, Kun-Tang Shen, Gang Lu, Gang Fu, Ming Zhong, Shu-Hua Xu, Wen-Yi Gu, Wei Huang, Xin-Tai Zhao, Geng-Xi Hu, Jian-Ren Gu, Zhu Chen, Ze-Guang Han

Proc Natl Acad Sci U S A. 2001 Dec 18; 98(26): 15089–15094. doi: 10.1073/pnas.241522398

PMCID:: PMC64988

Abstract Article PDF–341K

Select item 642645515.

Mapping the genetic landscape of human cells

Max A. Horlbeck, Albert Xu, Min Wang, Neal K. Bennett, Chong Y. Park, Derek Bogdanoff, Britt Adamson, Eric D. Chow, Martin Kampmann, Tim R. Peterson, Ken Nakamura, Michael A. Fischbach, Jonathan S. Weissman, Luke A. Gilbert

Cell. Author manuscript; available in PMC 2019 Aug 9.

Published in final edited form as: Cell. 2018 Aug 9; 174(4): 953–967.e22. Published online 2018 Jul 19. doi: 10.1016/j.cell.2018.06.010

PMCID:: PMC6426455

Abstract Article PDF–3.6M

Select item 775805016.

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele

PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975

PMCID:: PMC7758050

Abstract Article PDF–4.2M

Select item 298946117.

Systematic Characterization of Human Protein Complexes Identifies Chromosome Segregation Proteins

James R.A. Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M. Sykora, Martina Augsburg, Otto Hudecz, Bettina A. Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei Pozniakovsky, Mikolaj Michal Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters

Science. Author manuscript; available in PMC 2010 Nov 22.

Published in final edited form as: Science. 2010 Apr 30; 328(5978): 593–599. Published online 2010 Apr 1. doi: 10.1126/science.1181348

PMCID:: PMC2989461

Abstract Article PDF–2.2M

Select item 732206718.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 874895819.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 347780420.

A Census of Human Soluble Protein Complexes

Pierre C. Havugimana, G. Traver Hart, Tamás Nepusz, Haixuan Yang, Andrei L. Turinsky, Zhihua Li, Peggy I. Wang, Daniel R. Boutz, Vincent Fong, Sadhna Phanse, Mohan Babu, Stephanie A. Craig, Pingzhao Hu, Cuihong Wan, James Vlasblom, Vaqaarun-Nisa Dar, Alexander Bezginov, Gregory W. Clark, Gabriel C. Wu, Shoshana J. Wodak, Elisabeth R.M. Tillier, Alberto Paccanaro, Edward M. Marcotte, Andrew Emili

Cell. Author manuscript; available in PMC 2013 Aug 31.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 1068–1081. doi: 10.1016/j.cell.2012.08.011

PMCID:: PMC3477804

Abstract Article PDF–7.7M

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