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Select item 90714731.

The F-box protein, FBXO7, is required to maintain chromosome stability in humans

Michaela C L Palmer, Nicole M Neudorf, Ally C Farrell, Tooba Razi, Zelda Lichtensztejn, Kirk J McManus

Hum Mol Genet. 2022 May 1; 31(9): 1471–1486. Published online 2021 Nov 15. doi: 10.1093/hmg/ddab330

PMCID:: PMC9071473

Abstract Article PDF–1.9M

Select item 81105112.

Novel compound heterozygous FBXO7 mutations in a family with early onset Parkinson’s disease

Oswaldo Lorenzo-Betancor, Yi-Han Lin, Ali Samii, Suman Jayadev, Hojoong M. Kim, Katelan Longfellow, B. Jane Distad, Dora Yearout, Ignacio F. Mata, Cyrus P. Zabetian

Parkinsonism Relat Disord. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Parkinsonism Relat Disord. 2020 Nov; 80: 142–147. Published online 2020 Sep 22. doi: 10.1016/j.parkreldis.2020.09.035

PMCID:: PMC8110511

Abstract Article PDF–404K

Select item 74393413.

Compound heterozygous variants of the FBXO7 gene resulting in infantile‐onset Parkinsonian‐pyramidal syndrome in siblings of a Chinese family

Xiaohua Jin, Lisha An, Shengju Hao, Qian Liu, Qinhua Zhang, Xing Wang, Xuan Feng, Chuan Zhang, Xiaofang Cao, Yousheng Yan, Xu Ma

J Clin Lab Anal. 2020 Aug; 34(8): e23324. Published online 2020 Apr 10. doi: 10.1002/jcla.23324

PMCID:: PMC7439341

Abstract Article PDF–812K

Select item 52604904.

Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation

Marta Delgado-Camprubi, Noemi Esteras, Marc PM Soutar, Helene Plun-Favreau, Andrey Y Abramov

Cell Death Differ. 2017 Jan; 24(1): 120–131. Published online 2016 Sep 30. doi: 10.1038/cdd.2016.104

Correction in:: Cell Death Differ. 2017 Dec; 24(12): 2210.

PMCID:: PMC5260490

Abstract Article PDF–2.7M

Select item 111535255.

FBXO7 ubiquitinates PRMT1 to suppress serine synthesis and tumor growth in hepatocellular carcinoma

Li Luo, Xingyun Wu, Jiawu Fan, Lixia Dong, Mao Wang, Yan Zeng, Sijia Li, Wenyong Yang, Jingwen Jiang, Kui Wang

Nat Commun. 2024; 15: 4790. Published online 2024 Jun 5. doi: 10.1038/s41467-024-49087-2

PMCID:: PMC11153525

Abstract Article PDF–3.6M

Select item 106678386.

FBXO7 Confers Mesenchymal Properties and Chemoresistance in Glioblastoma by Controlling Rbfox2‐Mediated Alternative Splicing

Shangbiao Li, Yanwen Chen, Yuxin Xie, Hongchao Zhan, Yu Zeng, Kunlin Zeng, Li Wang, Ziling Zhan, Cuiying Li, Liqian Zhao, Xiaoxia Chen, Yujing Tan, Zhongyong Wang, Junguo Bu, Ye Song, Fan Deng, Aidong Zhou

Adv Sci (Weinh) 2023 Nov; 10(33): 2303561. Published online 2023 Oct 11. doi: 10.1002/advs.202303561

PMCID:: PMC10667838

Abstract Article PDF–5.8M

Select item 105974847.

USP7 attenuates endoplasmic reticulum stress-induced apoptotic cell death through deubiquitination and stabilization of FBXO7

Su Hyoun Lee, Kwang Chul Chung

PLoS One. 2023; 18(10): e0290371. Published online 2023 Oct 24. doi: 10.1371/journal.pone.0290371

Correction in:: PLoS One. 2024; 19(1): e0297970.

PMCID:: PMC10597484

Abstract Article PDF–2.1M

Select item 102849178.

FBXO7, a tumor suppressor in endometrial carcinoma, suppresses INF2-associated mitochondrial division

Hui Zhang, Yiting Zhao, Jie Wang, Jinyun Li, Jingyi Xia, Yan Lin, Yeling Zhong, Xinyi Cao, Jiabei Jin, Xinming Li, Weili Yang, Meng Ye, Xiaofeng Jin

Cell Death Dis. 2023 Jun; 14(6): 368. Published online 2023 Jun 21. doi: 10.1038/s41419-023-05891-0

PMCID:: PMC10284917

Abstract Article PDF–9.3M

Select item 88255599.

The long non-coding RNA rhabdomyosarcoma 2-associated transcript exerts anti-tumor effects on lung adenocarcinoma via ubiquitination of SOX9

Yaofei Pei, Bing Zhou, Xiqiang Liu

Ann Transl Med. 2022 Jan; 10(1): 10. doi: 10.21037/atm-21-6052

PMCID:: PMC8825559

Abstract Article PDF–2.2M

Select item 647508910.

A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity

Jiye Liu, Tianyu Song, Wenrong Zhou, Lijie Xing, Su Wang, Matthew Ho, Zhengang Peng, Yu-Tzu Tai, Teru Hideshima, Kenneth C. Anderson, Yong Cang

Leukemia. Author manuscript; available in PMC 2019 Apr 20.

Published in final edited form as: Leukemia. 2019 Jan; 33(1): 171–180. Published online 2018 Jul 19. doi: 10.1038/s41375-018-0205-y

PMCID:: PMC6475089

Abstract Article PDF–770K

Select item 311788011.

Expression of Fbxo7 in Haematopoietic Progenitor Cells Cooperates with p53 Loss to Promote Lymphomagenesis

Mikhail Lomonosov, El Kahina Meziane, Hongtao Ye, David E. Nelson, Suzanne J. Randle, Heike Laman

PLoS One. 2011; 6(6): e21165. Published online 2011 Jun 17. doi: 10.1371/journal.pone.0021165

PMCID:: PMC3117880

Abstract Article PDF–3.3M

Select item 303793912.

Loss of Nuclear Activity of the FBXO7 Protein in Patients with Parkinsonian-Pyramidal Syndrome (PARK15)

Tianna Zhao, Esther De Graaff, Guido J. Breedveld, Agnese Loda, Lies-Anne Severijnen, Cokkie H. Wouters, Frans W. Verheijen, Marieke C. J. Dekker, Pasquale Montagna, Rob Willemsen, Ben A. Oostra, Vincenzo Bonifati

PLoS One. 2011; 6(2): e16983. Published online 2011 Feb 11. doi: 10.1371/journal.pone.0016983

PMCID:: PMC3037939

Abstract Article PDF–2.6M

Select item 997131913.

E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide

Su Hyoun Lee, Yun Ju Lee, Sungyeon Jung, Kwang Chul Chung

J Biol Chem. 2023 Mar; 299(3): 102909. Published online 2023 Jan 13. doi: 10.1016/j.jbc.2023.102909

PMCID:: PMC9971319

Abstract Article PDF–2.9M

Select item 917840914.

Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells

Rebecca Harris, Ming Yang, Christina Schmidt, Chloe Royet, Sarbjit Singh, Amarnath Natarajan, May Morris, Christian Frezza, Heike Laman

J Cell Biol. 2022 Jul 4; 221(7): e202203095. Published online 2022 Jun 7. doi: 10.1083/jcb.202203095

PMCID:: PMC9178409

Abstract Article PDF–4.3M

Select item 808227615.

Analysis of the FBXO7 promoter reveals overlapping Pax5 and c-Myb binding sites functioning in B cells

Rebecca Harris, Suzanne Randle, Heike Laman

Biochem Biophys Res Commun. 2021 May 21; 554: 41–48. doi: 10.1016/j.bbrc.2021.03.052

PMCID:: PMC8082276

Abstract Article

Select item 614588116.

Genetic analysis of ATP13A2, PLA2G6 and FBXO7 in a cohort of Chinese patients with early-onset Parkinson’s disease

Ting Shen, Jiali Pu, Hsin-Yi Lai, Lingjia Xu, Xiaoli Si, Yaping Yan, Yasi Jiang, Baorong Zhang

Sci Rep. 2018; 8: 14028. Published online 2018 Sep 19. doi: 10.1038/s41598-018-32217-4

PMCID:: PMC6145881

Abstract Article PDF–4.3M

Select item 452710417.

Status of the Parkinson’s disease gene family expression in non-small-cell lung cancer

Quan Xing Liu, Hong Zheng, Xu Feng Deng, Dong Zhou, Ji Gang Dai

World J Surg Oncol. 2015; 13: 238. Published online 2015 Aug 7. doi: 10.1186/s12957-015-0646-y

PMCID:: PMC4527104

Abstract Article PDF–575K

Select item 410073518.

FBXO7 Y52C Polymorphism as a Potential Protective Factor in Parkinson's Disease

Chiung-Mei Chen, I-Cheng Chen, Yi-Cheng Huang, Hsueh-Fen Juan, Ying-Lin Chen, Yi-Chun Chen, Chih-Hsin Lin, Li-Ching Lee, Chi-Mei Lee, Guey-Jen Lee-Chen, Yun-Ju Lai, Yih-Ru Wu

PLoS One. 2014; 9(7): e101392. Published online 2014 Jul 16. doi: 10.1371/journal.pone.0101392

PMCID:: PMC4100735

Abstract Article PDF–2.3M

Select item 382298419.

Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling

Hendrik J Kuiken, David A Egan, Heike Laman, Rene Bernards, Roderick L Beijersbergen, Annette M Dirac

J Cell Mol Med. 2012 Sep; 16(9): 2140–2149. Published online 2012 Aug 23. doi: 10.1111/j.1582-4934.2012.01524.x

PMCID:: PMC3822984

Abstract Article PDF–415K

Select item 806300020.

The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway

Valentine Spagnol, Caio A.B. Oliveira, Suzanne J. Randle, Patrícia M.S. Passos, Camila R.S.T.B. Correia, Natália B. Simaroli, Joice S. Oliveira, Tycho E.T. Mevissen, Ana Carla Medeiros, Marcelo D. Gomes, David Komander, Heike Laman, Felipe Roberti Teixeira

Biochim Biophys Acta Gen Subj. 2021 Jan; 1865(1): 129754. doi: 10.1016/j.bbagen.2020.129754

PMCID:: PMC8063000

Abstract Article

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PMC Links for Gene (Select 25793) (77)
PMC
lathosterol oxidase [Cricetulus griseus]
lathosterol oxidase [Cricetulus griseus]
gi|354498633|ref|XP_003511419.1|

Protein
Homo sapiens N-terminal glutamine amidase 1 (NTAQ1), transcript variant 3, mRNA
Homo sapiens N-terminal glutamine amidase 1 (NTAQ1), transcript variant 3, mRNA
gi|545686870|ref|NM_001283027.1|

Nucleotide
Klebsiella pneumoniae isolate from blood culture 15-3
Klebsiella pneumoniae isolate from blood culture 15-3

biosample
Klebsiella pneumoniae isolate from blood culture 10-12
Klebsiella pneumoniae isolate from blood culture 10-12

biosample

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