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Select item 104782831.

BM-MSCs display altered gene expression profiles in B-cell acute lymphoblastic leukemia niches and exert pro-proliferative effects via overexpression of IFI6

Chengyun Pan, Tianzhen Hu, Ping Liu, Dan Ma, Shuyun Cao, Qin Shang, Luxin Zhang, Qingzhen Chen, Qin Fang, Jishi Wang

J Transl Med. 2023; 21: 593. Published online 2023 Sep 5. doi: 10.1186/s12967-023-04464-1

PMCID:: PMC10478283

Abstract Article PDF–3.0M

Select item 99230102.

Interferon alpha inducible protein 6 is a negative regulator of innate immune responses by modulating RIG-I activation

Laura Villamayor, Vanessa Rivero, Darío López-García, David J. Topham, Luis Martínez-Sobrido, Aitor Nogales, Marta L. DeDiego

Front Immunol. 2023; 14: 1105309. Published online 2023 Jan 30. doi: 10.3389/fimmu.2023.1105309

PMCID:: PMC9923010

Abstract Article PDF–5.8M

Select item 80470773.

The Functional and Antiviral Activity of Interferon Alpha-Inducible IFI6 Against Hepatitis B Virus Replication and Gene Expression

Muhammad Sajid, Hafiz Ullah, Kun Yan, Miao He, Jiangpeng Feng, Muhammad Adnan Shereen, Ruidong Hao, Qiaohong Li, Deyin Guo, Yu Chen, Li Zhou

Front Immunol. 2021; 12: 634937. Published online 2021 Apr 1. doi: 10.3389/fimmu.2021.634937

PMCID:: PMC8047077

Abstract Article PDF–7.6M

Select item 73884764.

IFI6 depletion inhibits esophageal squamous cell carcinoma progression through reactive oxygen species accumulation via mitochondrial dysfunction and endoplasmic reticulum stress

Zhenchuan Liu, Shaorui Gu, Tiancheng Lu, Kaiqing Wu, Lei Li, Chenglai Dong, Yongxin Zhou

J Exp Clin Cancer Res. 2020; 39: 144. Published online 2020 Jul 29. doi: 10.1186/s13046-020-01646-3

PMCID:: PMC7388476

Abstract Article PDF–7.7M

Select item 60352665.

G1P3 (IFI6), a mitochondrial localised antiapoptotic protein, promotes metastatic potential of breast cancer cells through mtROS

Venugopalan Cheriyath, Jaspreet Kaur, Anne Davenport, Ashjan Khalel, Nobel Chowdhury, Lalitha Gaddipati

Br J Cancer. 2018 Jul 3; 119(1): 52–64. Published online 2018 Jun 14. doi: 10.1038/s41416-018-0137-3

PMCID:: PMC6035266

Abstract Article PDF–2.1M

Select item 53383886.

Systematic identification of anti-interferon function on hepatitis C virus genome reveals p7 as an immune evasion protein

Hangfei Qi, Virginia Chu, Nicholas C. Wu, Zugen Chen, Shawna Truong, Gurpreet Brar, Sheng-Yao Su, Yushen Du, Vaithilingaraja Arumugaswami, C. Anders Olson, Shu-Hua Chen, Chung-Yen Lin, Ting-Ting Wu, Ren Sun

Proc Natl Acad Sci U S A. 2017 Feb 21; 114(8): 2018–2023. Published online 2017 Feb 3. doi: 10.1073/pnas.1614623114

PMCID:: PMC5338388

Abstract Article PDF–1.0M

Select item 45265567.

IFI6 Inhibits Apoptosis via Mitochondrial-Dependent Pathway in Dengue Virus 2 Infected Vascular Endothelial Cells

Yiming Qi, Ying Li, Yingke Zhang, Lin Zhang, Zilian Wang, Xuzhi Zhang, Lian Gui, Junqi Huang

PLoS One. 2015; 10(8): e0132743. Published online 2015 Aug 5. doi: 10.1371/journal.pone.0132743

Correction in:: PLoS One. 2015; 10(9): e0138896.

PMCID:: PMC4526556

Abstract Article PDF–2.1M

Select item 43046248.

No transmission of hepatitis E virus in pigs fed diets containing commercial spray-dried porcine plasma: a retrospective study of samples from several swine trials

Joan Pujols, Carmen Rodríguez, Nuria Navarro, Sonia Pina-Pedrero, Joy M Campbell, Joe Crenshaw, Javier Polo

Virol J. 2014; 11: 232. Published online 2014 Dec 24. doi: 10.1186/s12985-014-0232-x

PMCID:: PMC4304624

Abstract Article PDF–443K

Select item 19645099.

G1P3, an IFN-induced survival factor, antagonizes TRAIL-induced apoptosis in human myeloma cells

Venugopalan Cheriyath, Keith B. Glaser, Jeffrey F. Waring, Rachid Baz, Mohamad A. Hussein, Ernest C. Borden

J Clin Invest. 2007 Oct 1; 117(10): 3107–3117. Published online 2007 Sep 6. doi: 10.1172/JCI31122

PMCID:: PMC1964509

Abstract Article PDF–1.7M

Select item 116698510.

Characterization of a human gene inducible by alpha- and beta-interferons and its expression in mouse cells.

J M Kelly, A C Porter, Y Chernajovsky, C S Gilbert, G R Stark, I M Kerr

EMBO J. 1986 Jul; 5(7): 1601–1606. doi: 10.1002/j.1460-2075.1986.tb04402.x

PMCID:: PMC1166985

Summary Page Browse PDF–1.5M

Select item 45421811.

Interferon response element of the human gene 6-16.

A C Porter, Y Chernajovsky, T C Dale, C S Gilbert, G R Stark, I M Kerr

EMBO J. 1988 Jan; 7(1): 85–92. doi: 10.1002/j.1460-2075.1988.tb02786.x

PMCID:: PMC454218

Summary Page Browse PDF–1.8M

Select item 32847112.

Targeted disruption of a human interferon-inducible gene detected by secretion of human growth hormone.

J E Itzhaki, A C Porter

Nucleic Acids Res. 1991 Jul 25; 19(14): 3835–3842. doi: 10.1093/nar/19.14.3835

PMCID:: PMC328471

Summary Page Browse PDF–1.7M

Select item 30695413.

Characterisation of a novel minisatellite that provides multiple splice donor sites in an interferon-induced transcript.

M G Turri, K A Cuin, A C Porter

Nucleic Acids Res. 1995 Jun 11; 23(11): 1854–1861. doi: 10.1093/nar/23.11.1854

PMCID:: PMC306954

Summary Page Browse PDF–1.8M

Select item 620221014.

A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication

R. Blake Richardson, Maikke B. Ohlson, Jennifer L. Eitson, Ashwani Kumar, Matthew B. McDougal, Ian N. Boys, Katrina B. Mar, Pamela C. De La Cruz-Rivera, Connor Douglas, Genevieve Konopka, Chao Xing, John W. Schoggins

Nat Microbiol. 2018; 3(11): 1214–1223. Published online 2018 Sep 17. doi: 10.1038/s41564-018-0244-1

PMCID:: PMC6202210

Abstract Article PDF–4.1M

Select item 257261115.

Inhibition of G1P3 expression found in the differential display study on respiratory syncytial virus infection

Dongchi Zhao, Dan Peng, Lei Li, Qiwei Zhang, Chuyu Zhang

Virol J. 2008; 5: 114. Published online 2008 Oct 6. doi: 10.1186/1743-422X-5-114

PMCID:: PMC2572611

Abstract Article PDF–367K

Select item 1103432116.

G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell

Eiji Tahara, Jr, Hidetoshi Tahara, Masamoto Kanno, Kazuhito Naka, Yayoi Takeda, Takeshi Matsuzaki, Ryuta Yamazaki, Hiroto Ishihara, Wataru Yasui, J Carl Barrett, Toshinori Ide, Eiichi Tahara

Cancer Immunol Immunother. 2005 Aug; 54(8): 729–740. Published online 2005 Feb 1. doi: 10.1007/s00262-004-0645-2