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Items: 1 to 20 of 149

1.
Rictor mediates p53 deactivation to facilitate the malignant transformation of hepatocytes and promote hepatocarcinogenesis
Chun Wang, Hui Kang, Yun Yi, Yang Ding, Fan Wang, Jie Luo, Mingliang Ye, Yinghui Hong, Chao Xia, Junwei Yan, Lan Liu, Jing Liu, Zibiao Zhong, Zhonglin Zhang, Qiu Zhao, Ying Chang
J Transl Med. 2023; 21: 919. Published online 2023 Dec 18. doi: 10.1186/s12967-023-04799-9
PMCID:
PMC10729423
AbstractArticlePDF–3.3M
2.
Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing
Dániel Sztankovics, Ildikó Krencz, Dorottya Moldvai, Titanilla Dankó, Ákos Nagy, Noémi Nagy, Gábor Bedics, András Rókusz, Gergő Papp, Anna-Mária Tőkés, Judit Pápay, Zoltán Sápi, Katalin Dezső, Csaba Bödör, Anna Sebestyén
Sci Rep. 2023; 13: 19610. Published online 2023 Nov 10. doi: 10.1038/s41598-023-46927-x
PMCID:
PMC10638425
AbstractArticlePDF–1.3M
3.
Rictor amplification promotes NSCLC cell proliferation through formation and activation of mTORC2 at the expense of mTORC1
Laura C. Kim, Christopher H. Rhee, Jin Chen
Mol Cancer Res. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Mol Cancer Res. 2020 Nov; 18(11): 1675–1684. Published online 2020 Aug 14. doi: 10.1158/1541-7786.MCR-20-0262
PMCID:
PMC7642103
AbstractArticlePDF–1.9M
4.
The role of RICTOR amplification in targeted therapy and drug resistance
Deze Zhao, Man Jiang, Xiaochun Zhang, Helei Hou
Mol Med. 2020; 26: 20. Published online 2020 Feb 10. doi: 10.1186/s10020-020-0146-6
PMCID:
PMC7011243
AbstractArticlePDF–1.0M
5.
Rictor negatively regulates FcεRI-induced mast cell degranulation
Daniel Smrz, Glenn Cruse, Michael A. Beaven, Arnold Kirshenbaum, Dean D. Metcalfe, Alasdair M. Gilfillan
J Immunol. Author manuscript; available in PMC 2015 Dec 15.
Published in final edited form as: J Immunol. 2014 Dec 15; 193(12): 5924–5932. Published online 2014 Nov 5. doi: 10.4049/jimmunol.1303495
PMCID:
PMC4258480
AbstractArticlePDF–1.9M
6.
Rictor is an independent prognostic factor for endometrial carcinoma
Shan-Yun Wen, Chang-Hua Li, Yan-Li Zhang, Yu-Hai Bian, Li Ma, Qiu-Lin Ge, Yin-Cheng Teng, Zhi-Gang Zhang
Int J Clin Exp Pathol. 2014; 7(5): 2068–2078. Published online 2014 Apr 15.
PMCID:
PMC4069916
AbstractArticlePDF–1.6M
7.
The mTORC2 Component Rictor Contributes to Cisplatin Resistance in Human Ovarian Cancer Cells
Akechai Im-aram, Lee Farrand, Seung-Min Bae, Gwonhwa Song, Yong Sang Song, Jae Yong Han, Benjamin K. Tsang
PLoS One. 2013; 8(9): e75455. Published online 2013 Sep 23. doi: 10.1371/journal.pone.0075455
PMCID:
PMC3781115
AbstractArticlePDF–1.7M
8.
Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt
Zanlin Yu, Junliang Chen, Enzo Takagi, Feng Wang, Bidisha Saha, Xi Liu, Lydia-Marie Joubert, Catherine E. Gleason, Mingliang Jin, Chengmin Li, Carlos Nowotny, David Agard, Yifan Cheng, David Pearce
J Biol Chem. 2022 Sep; 298(9): 102288. Published online 2022 Aug 1. doi: 10.1016/j.jbc.2022.102288
PMCID:
PMC9440446
AbstractArticlePDF–2.8M
9.
Raptor and rictor expression in patients with human papillomavirus-related oropharyngeal squamous cell carcinoma
Shunsuke Kondo, Hitoshi Hirakawa, Taro Ikegami, Takayuki Uehara, Shinya Agena, Jin Uezato, Hidetoshi Kinjyo, Noritomo Kise, Yukashi Yamashita, Katsunori Tanaka, Narumi Hasegawa, Asanori Kiyuna, Hiroyuki Maeda, Mikio Suzuki, Akira Gahana
BMC Cancer. 2021; 21: 87. Published online 2021 Jan 22. doi: 10.1186/s12885-021-07794-9
PMCID:
PMC7821513
AbstractArticlePDF–5.3M
10.
Rictor promotes cell migration and actin polymerization through regulating ABLIM1 phosphorylation in Hepatocellular Carcinoma
Xin Dong, Mei Feng, Hui Yang, Hengkang Liu, Hua Guo, Xianshu Gao, Yucun Liu, Rong Liu, Ning Zhang, Ruibing Chen, Ruirui Kong
Int J Biol Sci. 2020; 16(15): 2835–2852. Published online 2020 Sep 1. doi: 10.7150/ijbs.46285
PMCID:
PMC7545703
AbstractArticlePDF–3.7M
11.
Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis
Katharina M. Schmidt, Peter Dietrich, Christina Hackl, Jessica Guenzle, Peter Bronsert, Christine Wagner, Stefan Fichtner-Feigl, Hans J. Schlitt, Edward K. Geissler, Claus Hellerbrand, Sven A. Lang
Neoplasia. 2018 Dec; 20(12): 1198–1208. Published online 2018 Nov 4. doi: 10.1016/j.neo.2018.10.001
PMCID:
PMC6224335
AbstractArticlePDF–1.7M
12.
RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR
Nneha Sakre, Gary Wildey, Mohadese Behtaj, Adam Kresak, Michael Yang, Pingfu Fu, Afshin Dowlati
Oncotarget. 2017 Jan 24; 8(4): 5992–6002. Published online 2016 Nov 15. doi: 10.18632/oncotarget.13362
PMCID:
PMC5351607
AbstractArticlePDF–4.6M
13.
Evaluation of Akt and RICTOR Expression Levels in Astrocytomas of All Grades
Arthur William Alvarenga, Luis Eduardo Machado, Bruna Roz Rodrigues, Fernanda Cristina Sulla Lupinacci, Paulo Sanemastu, Eduardo Matta, Martín Roffé, Luís Fernando Bleggi Torres, Isabela Werneck da Cunha, Vilma Regina Martins, Glaucia Noeli Maroso Hajj
J Histochem Cytochem. 2017 Feb; 65(2): 93–103. Published online 2016 Oct 27. doi: 10.1369/0022155416675850
PMCID:
PMC5256195
AbstractArticlePDF–6.3M
14.
microRNA-153 Targets mTORC2 Component Rictor to Inhibit Glioma Cells
Yan Cui, Jizong Zhao, Lei Yi, Yugang Jiang
PLoS One. 2016; 11(6): e0156915. Published online 2016 Jun 13. doi: 10.1371/journal.pone.0156915
PMCID:
PMC4905671
AbstractArticlePDF–971K
15.
RICTOR amplification defines a novel subset of lung cancer patients who may benefit from treatment with mTOR1/2 inhibitors
Haiying Cheng, Yiyu Zou, Jeffrey S. Ross, Kai Wang, Xuewen Liu, Balazs Halmos, Siraj M Ali, Huijie Liu, Amit Verma, Cristina Montagna, Abraham Chachoua, Sanjay Goel, Edward L. Schwartz, Changcheng Zhu, Jidong Shan, Yiting Yu, Kira Gritsman, Roman Yelensky, Doron Lipson, Geoff Otto, Matthew Hawryluk, Philip J. Stephens, Vincent A. Miller, Bilal Piperdi, Roman Perez-Soler
Cancer Discov. Author manuscript; available in PMC 2016 Jun 1.
Published in final edited form as: Cancer Discov. 2015 Dec; 5(12): 1262–1270. Published online 2015 Sep 14. doi: 10.1158/2159-8290.CD-14-0971
PMCID:
PMC4670806
AbstractArticlePDF–383K
16.
Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression
Kunihiko Yasuda, Mayumi Takahashi, Nozomu Mori
PLoS One. 2015; 10(11): e0142943. Published online 2015 Nov 23. doi: 10.1371/journal.pone.0142943
PMCID:
PMC4658088
AbstractArticlePDF–3.3M
17.
Identification of Rictor as a Novel Substrate of Polo-like kinase 1
Tian Shao, Xiaoqi Liu
Cell Cycle. 2015; 14(5): 755–760. Published online 2015 Feb 25. doi: 10.1080/15384101.2014.998050
PMCID:
PMC4615041
AbstractArticlePDF–407K
18.
Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance
Kenta Masui, Kazuhiro Tanaka, Shiro Ikegami, Genaro R. Villa, Huijun Yang, William H. Yong, Timothy F. Cloughesy, Kanato Yamagata, Nobutaka Arai, Webster K. Cavenee, Paul S. Mischel
Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30): 9406–9411. Published online 2015 Jul 13. doi: 10.1073/pnas.1511759112
PMCID:
PMC4522814
AbstractArticlePDF–1.4M
19.
Combined RNAi-Mediated Suppression of Rictor and EGFR Resulted in Complete Tumor Regression in an Orthotopic Glioblastoma Tumor Model
Maite Verreault, Sherry A. Weppler, Amelia Stegeman, Corinna Warburton, Dita Strutt, Dana Masin, Marcel B. Bally
PLoS One. 2013; 8(3): e59597. Published online 2013 Mar 15. doi: 10.1371/journal.pone.0059597
PMCID:
PMC3598699
AbstractArticlePDF–7.3M
20.
TARGETED INHIBITION OF mTOR SIGNALING INHIBITS TUMORIGENESIS OF COLORECTAL CANCER
Pat Gulhati, Qingsong Cai, Jing Li, Jianyu Liu, Piotr G. Rychahou, Suimin Qiu, Eun Y. Lee, Scott R. Silva, Kanika A. Bowen, Tianyan Gao, B. Mark Evers
Clin Cancer Res. Author manuscript; available in PMC 2010 Dec 1.
Published in final edited form as: Clin Cancer Res. 2009 Dec 1; 15(23): 7207–7216. Published online 2009 Nov 24. doi: 10.1158/1078-0432.CCR-09-1249
PMCID:
PMC2898570
AbstractArticlePDF–2.8M

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