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Select item 90766711.

Cytochrome P450 2E1 predicts liver functional recovery from donation after circulatory death using air-ventilated normothermic machine perfusion

Ji-Hua Shi, Dong-Jing Yang, Qiang Jin, Nuo Cheng, Yuan-Bin Shi, Yang Bai, Dong-Sheng Yu, Wen-Zhi Guo, Guang-Bo Ge, Shui-Jun Zhang

Sci Rep. 2022; 12: 7446. Published online 2022 May 6. doi: 10.1038/s41598-022-11434-y

PMCID:: PMC9076671

Abstract Article PDF–9.1M

Select item 70711092.

Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2E1 Enzyme Activity: Inhibitory Effect of Cytochrome P450 Enzyme CYP2E1 by Salicylic Acid in Rat Liver Microsomes

Hassan Salhab, Declan P. Naughton, James Barker

Molecules. 2020 Feb; 25(4): 932. Published online 2020 Feb 19. doi: 10.3390/molecules25040932

PMCID:: PMC7071109

Abstract Article PDF–1.2M

Select item 69342723.

NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways

Qin Lin, Xiaolin Kang, Xuefeng Li, Tao Wang, Fengting Liu, Jinxue Jia, Ziqi Jin, Yongzhi Xue

PLoS One. 2019; 14(12): e0225531. Published online 2019 Dec 27. doi: 10.1371/journal.pone.0225531

PMCID:: PMC6934272

Abstract Article PDF–2.5M

Select item 62730184.

Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes

Zhi-Juan Zhang, Zhao-Yang Xia, Jin-Mei Wang, Xue-Ting Song, Jin-Feng Wei, Wen-Yi Kang

Molecules. 2016 Jun; 21(6): 738. Published online 2016 Jun 14. doi: 10.3390/molecules21060738

PMCID:: PMC6273018

Abstract Article PDF–2.1M

Select item 57214375.

Increased ethanol‐inducible cytochrome P450‐2E1 and cytochrome P450 isoforms in exosomes of alcohol‐exposed rodents and patients with alcoholism through oxidative and endoplasmic reticulum stress

Young‐Eun Cho, Esteban Mezey, James P. Hardwick, Norman Salem, Jr., Dahn L. Clemens, Byoung‐Joon Song

Hepatol Commun. 2017 Sep; 1(7): 675–690. Published online 2017 Jul 13. doi: 10.1002/hep4.1066

PMCID:: PMC5721437

Abstract Article PDF–1.1M

Select item 57214006.

The role of human cytochrome P450 2E1 in liver inflammation and fibrosis

Jun Xu, Hsiao‐Yen Ma, Shuang Liang, Mengxi Sun, Gabriel Karin, Yukinori Koyama, Ronglin Hu, Oswald Quehenberger, Nicholas O. Davidson, Edward A. Dennis, Tatiana Kisseleva, David A. Brenner

Hepatol Commun. 2017 Dec; 1(10): 1043–1057. Published online 2017 Oct 30. doi: 10.1002/hep4.1115

PMCID:: PMC5721400

Abstract Article PDF–1.3M

Select item 49978537.

Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment

Hozeifa Mohamed Hassan, Hongli Guo, Bashir Alsiddig Yousef, Mounia Guerram, Aida Mejda Hamdi, Luyong Zhang, Zhenzhou Jiang

Antimicrob Agents Chemother. 2016 Sep; 60(9): 5285–5293. Prepublished online 2016 Jun 20. Published online 2016 Aug 22. doi: 10.1128/AAC.00854-16

PMCID:: PMC4997853

Abstract Article PDF–3.1M

Select item 46582308.

Subcellular Localization of Rat CYP2E1 Impacts Metabolic Efficiency toward Common Substrates

Jessica H. Hartman, H. Cass Martin, Andres A. Caro, Amy R. Pearce, Grover P. Miller

Toxicology. Author manuscript; available in PMC 2016 Dec 2.

Published in final edited form as: Toxicology. 2015 Dec 2; 338: 47–58. Published online 2015 Oct 14. doi: 10.1016/j.tox.2015.10.001

PMCID:: PMC4658230

Abstract Article PDF–571K

Select item 44021289.

Dietary tomato powder inhibits alcohol-induced hepatic injury by suppressing cytochrome p450 2E1 induction in rodent models

Camilla P. Stice, Chun Liu, Koichi Aizawa, Andrew S. Greenberg, Lynne M. Ausman, Xiang-Dong Wang

Arch Biochem Biophys. Author manuscript; available in PMC 2016 Apr 15.

Published in final edited form as: Arch Biochem Biophys. 2015 Apr 15; 572: 81–88. Published online 2015 Jan 12. doi: 10.1016/j.abb.2015.01.004

PMCID:: PMC4402128

Abstract Article PDF–1.5M

Select item 400316110.

ROS generated by CYP450, especially CYP2E1, mediate mitochondrial dysfunction induced by tetrandrine in rat hepatocytes

Xin-ming Qi, Ling-ling Miao, Yan Cai, Li-kun Gong, Jin Ren

Acta Pharmacol Sin. 2013 Sep 5; 34(9): 1229–1236. Published online 2013 Jul 29. doi: 10.1038/aps.2013.62

PMCID:: PMC4003161

Abstract Article PDF–1.8M

Select item 396032511.

Chronic Ethanol Ingestion Induces Oxidative Kidney Injury through Taurine-inhibitable Inflammation

Calivarathan Latchoumycandane, Laura E. Nagy, Thomas M. McIntyre

Free Radic Biol Med. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Free Radic Biol Med. 2014 Apr; 69: 403–416. Published online 2014 Jan 8. doi: 10.1016/j.freeradbiomed.2014.01.001

PMCID:: PMC3960325

Abstract Article PDF–3.1M

Select item 380011712.

Bimodal Targeting of Microsomal CYP2E1 to Mitochondria through Activation of an N-terminal Chimeric Signal by cAMP-mediated Phosphorylation

Marie-Anne Robin, Hindupur K. Anandatheerthavarada, Gopa Biswas, Naresh Babu V. Sepuri, Donna M. Gordon, Debkumar Pain, Narayan G. Avadhani

J Biol Chem. Author manuscript; available in PMC 2013 Oct 19.

Published in final edited form as: J Biol Chem. 2002 Oct 25; 277(43): 40583–40593. Published online 2002 Aug 20. doi: 10.1074/jbc.M203292200

PMCID:: PMC3800117

Abstract Article PDF–5.7M

Select item 360965413.

Cytochrome P450 2E1 inhibition prevents hepatic carcinogenesis induced by diethylnitrosamine in alcohol-fed rats

Qinyuan Ye, Fuzhi Lian, Pollyanna R.G. Chavez, Jayong Chung, Wenhua Ling, Hua Qin, Helmut K. Seitz, Xiang-Dong Wang

Hepatobiliary Surg Nutr. 2012 Dec; 1(1): 5–18. doi: 10.3978/j.issn.2304-3881.2012.11.05

PMCID:: PMC3609654

Abstract Article PDF–1.8M

Select item 344727714.

Coexistence of hyperlipidemia and acute cerebral ischemia/reperfusion induces severe liver damage in a rat model

Wei-Hong Gong, Wen-Xia Zheng, Jun Wang, Shi-Hui Chen, Bo Pang, Xia-Min Hu, Xiao-Lu Cao

World J Gastroenterol. 2012 Sep 21; 18(35): 4934–4943. Published online 2012 Sep 21. doi: 10.3748/wjg.v18.i35.4934

PMCID:: PMC3447277

Abstract Article PDF–1.3M

Select item 300082115.

Acetaminophen Induces Apoptosis in Rat Cortical Neurons

Inmaculada Posadas, Pablo Santos, Almudena Blanco, Maríangeles Muñoz-Fernández, Valentín Ceña

PLoS One. 2010; 5(12): e15360. Published online 2010 Dec 10. doi: 10.1371/journal.pone.0015360

PMCID:: PMC3000821

Abstract Article PDF–814K

Select item 291569716.

Mitochondria-targeted Cytochrome P450 2E1 Induces Oxidative Damage and Augments Alcohol-mediated Oxidative Stress

Seema Bansal, Chuan-Peng Liu, Naresh B. V. Sepuri, Hindupur K. Anandatheerthavarada, Venkatesh Selvaraj, Jan Hoek, Ginger L. Milne, F. Peter Guengerich, Narayan G. Avadhani

J Biol Chem. 2010 Aug 6; 285(32): 24609–24619. Published online 2010 Jun 7. doi: 10.1074/jbc.M110.121822

PMCID:: PMC2915697

Abstract Article PDF–2.2M

Select item 291107317.

Increased Cytochrome P4502E1 Expression and Altered Hydroxyeicosatetraenoic Acid Formation Mediate Diabetic Vascular Dysfunction: Rescue by Guanylyl-Cyclase Activation

Andreas Schäfer, Paolo Galuppo, Daniela Fraccarollo, Christian Vogt, Julian D. Widder, Julia Pfrang, Piet Tas, Eduardo Barbosa-Sicard, Hartmut Ruetten, Georg Ertl, Ingrid Fleming, Johann Bauersachs

Diabetes. 2010 Aug; 59(8): 2001–2009. Published online 2010 Jun 3. doi: 10.2337/db09-1668

PMCID:: PMC2911073

Abstract Article PDF–469K

Select item 188418118.

Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans

Zaiqi Wang, Stephen D Hall, Juan F Maya, Lang Li, Ali Asghar, J C Gorski

Br J Clin Pharmacol. 2003 Jan; 55(1): 77–85. doi: 10.1046/j.1365-2125.2003.01731.x

PMCID:: PMC1884181

Abstract Article PDF–125K

Select item 862235119.

Synbiotics Alleviate Hepatic Damage, Intestinal Injury and Muscular Beclin-1 Elevation in Rats after Chronic Ethanol Administration

Yi-Hsiu Chen, Wan-Chun Chiu, Qian Xiao, Ya-Ling Chen, Hitoshi Shirakawa, Suh-Ching Yang

Int J Mol Sci. 2021 Nov; 22(22): 12547. Published online 2021 Nov 21. doi: 10.3390/ijms222212547

PMCID:: PMC8622351

Abstract Article PDF–5.5M

Select item 771957720.

Alcohol Suppresses Cardiovascular Diurnal Variations in Male Normotensive Rats: Role of Reduced PER2 Expression and CYP2E1 Hyperactivity in the Heart

Mohamed Katary, Abdel A. Abdel-Rahman

Alcohol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Alcohol. 2020 Dec; 89: 27–36. Published online 2020 Aug 7. doi: 10.1016/j.alcohol.2020.08.001

PMCID:: PMC7719577

Abstract Article PDF–1.6M

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PMC Links for Gene (Select 25086) (53)
PMC
sex hormone-binding globulin isoform 4 precursor [Homo sapiens]
sex hormone-binding globulin isoform 4 precursor [Homo sapiens]
gi|226371613|ref|NP_001139753.1|

Protein
glycosyl hydrolase family 18 protein [Pilibacter termitis]
glycosyl hydrolase family 18 protein [Pilibacter termitis]
gi|1154900563|ref|WP_078806527.1|

Protein
chitinase B [Listeria monocytogenes]
chitinase B [Listeria monocytogenes]
gi|1708609693|gb|QDQ46649.1|

Protein

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