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Select item 108795111.

Multi-level profiling of the Fmr1 KO rat unveils altered behavioral traits along with aberrant glutamatergic function

George Ntoulas, Charalampos Brakatselos, Gerasimos Nakas, Michail-Zois Asprogerakas, Foteini Delis, Leonidas J. Leontiadis, George Trompoukis, Costas Papatheodoropoulos, Dimitrios Gkikas, Dimitrios Valakos, Giannis Vatsellas, Panagiotis K. Politis, Alexia Polissidis, Katerina Antoniou

Transl Psychiatry. 2024; 14: 104. Published online 2024 Feb 20. doi: 10.1038/s41398-024-02815-0

PMCID:: PMC10879511

Abstract Article PDF–2.1M

Select item 107222412.

Rescue of sharp wave-ripples and prevention of network hyperexcitability in the ventral but not the dorsal hippocampus of a rat model of fragile X syndrome

Leonidas J. Leontiadis, George Trompoukis, Giota Tsotsokou, Athina Miliou, Panagiotis Felemegkas, Costas Papatheodoropoulos

Front Cell Neurosci. 2023; 17: 1296235. Published online 2023 Dec 1. doi: 10.3389/fncel.2023.1296235

PMCID:: PMC10722241

Abstract Article PDF–8.0M

Select item 100824633.

Ribosomes in RNA Granules Are Stalled on mRNA Sequences That Are Consensus Sites for FMRP Association

Mina N. Anadolu, Jingyu Sun, Senthilkumar Kailasam, Kleanthi Chalkiadaki, Konstanze Krimbacher, Jewel T-Y. Li, Teodora Markova, Seyed M. Jafarnejad, Francois Lefebvre, Joaquin Ortega, Christos G. Gkogkas, Wayne S. Sossin

J Neurosci. 2023 Apr 5; 43(14): 2440–2459. doi: 10.1523/JNEUROSCI.1002-22.2023

PMCID:: PMC10082463

Abstract Article PDF–4.9M

Select item 98005724.

FMR1 deletion in rats induces hyperactivity with no changes in striatal dopamine transporter availability

Annunziata D’Elia, Sara Schiavi, Antonia Manduca, Alessandro Rava, Valeria Buzzelli, Fabrizio Ascone, Tiziana Orsini, Sabrina Putti, Andrea Soluri, Filippo Galli, Alessandro Soluri, Maurizio Mattei, Rosella Cicconi, Roberto Massari, Viviana Trezza

Sci Rep. 2022; 12: 22535. Published online 2022 Dec 29. doi: 10.1038/s41598-022-26986-2

PMCID:: PMC9800572

Abstract Article PDF–3.1M

Select item 97645625.

Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X Syndrome

Antonis Asiminas, Sam A. Booker, Owen R. Dando, Zrinko Kozic, Daisy Arkell, Felicity H. Inkpen, Anna Sumera, Irem Akyel, Peter C. Kind, Emma R. Wood

Mol Autism. 2022; 13: 49. Published online 2022 Dec 20. doi: 10.1186/s13229-022-00528-z

PMCID:: PMC9764562

Abstract Article PDF–4.0M

Select item 91581706.

Fmr1 exon 14 skipping in late embryonic development of the rat forebrain

Juliana C. Corrêa-Velloso, Alessandra M. Linardi, Talita Glaser, Fernando J. Velloso, Maria P. Rivas, Renata E P. Leite, Lea T. Grinberg, Henning Ulrich, Michael R. Akins, Silvana Chiavegatto, Luciana A. Haddad

BMC Neurosci. 2022; 23: 32. Published online 2022 May 31. doi: 10.1186/s12868-022-00711-1

PMCID:: PMC9158170

Abstract Article PDF–2.0M

Select item 89558067.

Brain Cholesterol Biosynthetic Pathway Is Altered in a Preclinical Model of Fragile X Syndrome

Martina Parente, Claudia Tonini, Valeria Buzzelli, Emilia Carbone, Viviana Trezza, Valentina Pallottini

Int J Mol Sci. 2022 Mar; 23(6): 3408. Published online 2022 Mar 21. doi: 10.3390/ijms23063408

PMCID:: PMC8955806

Abstract Article PDF–1.3M

Select item 88838698.

FMRP Sustains Presynaptic Function via Control of Activity-Dependent Bulk Endocytosis

Katherine Bonnycastle, Peter C. Kind, Michael A. Cousin

J Neurosci. 2022 Feb 23; 42(8): 1618–1628. doi: 10.1523/JNEUROSCI.0852-21.2021

PMCID:: PMC8883869

Abstract Article PDF–2.4M

Select item 76085569.

Gamma power abnormalities in a Fmr1-targeted transgenic rat model of fragile X syndrome

Naoki Kozono, Ai Okamura, Sokichi Honda, Mitsuyuki Matsumoto, Takuma Mihara

Sci Rep. 2020; 10: 18799. Published online 2020 Nov 2. doi: 10.1038/s41598-020-75893-x

PMCID:: PMC7608556

Abstract Article PDF–3.5M

Select item 748329310.

Robust and replicable measurement for prepulse inhibition of the acoustic startle response

Eric A. Miller, David B. Kastner, Michael N. Grzybowski, Melinda R. Dwinell, Aron M. Geurts, Loren M. Frank

Mol Psychiatry. 2021; 26(6): 1909–1927. Published online 2020 Mar 6. doi: 10.1038/s41380-020-0703-y

PMCID:: PMC7483293

Abstract Article PDF–1.9M

Select item 742398611.

Reduced axonal caliber and structural changes in a rat model of Fragile X syndrome with a deletion of a K-Homology domain of Fmr1

Carla E. M. Golden, Yohan Yee, Victoria X. Wang, Hala Harony-Nicolas, Patrick R. Hof, Jason P. Lerch, Joseph D. Buxbaum

Transl Psychiatry. 2020; 10: 280. Published online 2020 Aug 12. doi: 10.1038/s41398-020-00943-x

PMCID:: PMC7423986

Abstract Article PDF–4.4M

Select item 729563912.

Cellular localization of the FMRP in rat retina

Ping-Ping Zhang, Hui-Hui Yao, An-Hui Zha, Xing-Yue Liu, Ke-Yu Fan, Yue Xu, Hui-Yao Yuan, Lei Li, Lie-Cheng Wang

Biosci Rep. 2020 Jun 26; 40(6): BSR20200570. Published online 2020 Jun 15. doi: 10.1042/BSR20200570

PMCID:: PMC7295639

Abstract Article PDF–2.0M

Select item 672952513.

Metabotropic Glutamate Receptor Activation Regulates Fragile X Mental Retardation Protein and Fmr1 mRNA Localization Differentially in Dendrites and at Synapses

Laura N. Antar, Rownak Afroz, Jason B. Dictenberg, Reed C. Carroll, Gary J. Bassell

J Neurosci. 2004 Mar 17; 24(11): 2648–2655. doi: 10.1523/JNEUROSCI.0099-04.2004

PMCID:: PMC6729525

Abstract Article PDF–708K

Select item 661357914.

Acute ethanol produces ataxia and induces Fmr1 expression via histone modifications in the rat cerebellum

Russell S. Dulman, James Auta, Tara Teppen, Subhash C. Pandey

Alcohol Clin Exp Res. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Alcohol Clin Exp Res. 2019 Jun; 43(6): 1191–1198. Published online 2019 May 14. doi: 10.1111/acer.14044

PMCID:: PMC6613579

Abstract Article PDF–1.2M

Select item 645891515.

Deletion of the KH1 Domain of Fmr1 Leads to Transcriptional Alterations and Attentional Deficits in Rats

Carla E M Golden, Michael S Breen, Lacin Koro, Sankalp Sonar, Kristi Niblo, Andrew Browne, Natalie Burlant, Daniele Di Marino, Silvia De Rubeis, Mark G Baxter, Joseph D Buxbaum, Hala Harony-Nicolas

Cereb Cortex. 2019 May; 29(5): 2228–2244. Published online 2019 Mar 16. doi: 10.1093/cercor/bhz029

PMCID:: PMC6458915

Abstract Article PDF–2.2M

Select item 558139916.

Loss of FMRP Impaired Hippocampal Long-Term Plasticity and Spatial Learning in Rats

Yonglu Tian, Chaojuan Yang, Shujiang Shang, Yijun Cai, Xiaofei Deng, Jian Zhang, Feng Shao, Desheng Zhu, Yunbo Liu, Guiquan Chen, Jing Liang, Qiang Sun, Zilong Qiu, Chen Zhang

Front Mol Neurosci. 2017; 10: 269. Published online 2017 Aug 28. doi: 10.3389/fnmol.2017.00269

PMCID:: PMC5581399

Abstract Article PDF–4.1M

Select item 496435217.

Sensory hypo-excitability in a rat model of fetal development in Fragile X Syndrome

Julia Berzhanskaya, Marnie A. Phillips, Jing Shen, Matthew T. Colonnese

Sci Rep. 2016; 6: 30769. Published online 2016 Jul 28. doi: 10.1038/srep30769

Correction in:: Sci Rep. 2017; 7: 44515.

PMCID:: PMC4964352

Abstract Article PDF–4.8M

Select item 403446918.

Degraded speech sound processing in a rat model of fragile X syndrome

Crystal T. Engineer, Tracy M. Centanni, Kwok W. Im, Kimiya C. Rahebi, Elizabeth P. Buell, Michael P. Kilgard

Brain Res. Author manuscript; available in PMC 2015 May 20.

Published in final edited form as: Brain Res. 2014 May 20; 1564: 72–84. Published online 2014 Apr 5. doi: 10.1016/j.brainres.2014.03.049

PMCID:: PMC4034469

Abstract Article PDF–1.5M

Select item 219573119.

Methylation-Dependent Gene Silencing Induced by Interleukin 1β via Nitric Oxide Production

Abdelkrim Hmadcha, Francisco J. Bedoya, Francisco Sobrino, Elizabeth Pintado

J Exp Med. 1999 Dec 6; 190(11): 1595–1604. doi: 10.1084/jem.190.11.1595

PMCID:: PMC2195731

Abstract Article PDF–231K

Select item 2468920.

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

Ivan Jeanne Weiler, Scott A. Irwin, Anna Y. Klintsova, Corinne M. Spencer, Anthony D. Brazelton, Kevin Miyashiro, Thomas A. Comery, Bindu Patel, James Eberwine, William T. Greenough

Proc Natl Acad Sci U S A. 1997 May 13; 94(10): 5395–5400. doi: 10.1073/pnas.94.10.5395

PMCID:: PMC24689

Abstract Article PDF–537K

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PMC Links for Gene (Select 24948) (67)
PMC
fragile X messenger ribonucleoprotein 1 isoform 6 [Rattus norvegicus]
fragile X messenger ribonucleoprotein 1 isoform 6 [Rattus norvegicus]
gi|2772229952|ref|NP_001418540.1|

Protein
fragile X messenger ribonucleoprotein 1 isoform 1 [Rattus norvegicus]
fragile X messenger ribonucleoprotein 1 isoform 1 [Rattus norvegicus]
gi|2771821119|ref|NP_001418477.1|

Protein
Mus musculus beta-1,4-N-acetyl-galactosaminyl transferase 1 (B4galnt1), mRNA
Mus musculus beta-1,4-N-acetyl-galactosaminyl transferase 1 (B4galnt1), mRNA
gi|42476102|ref|NM_008080.3|

Nucleotide

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