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Select item 92585401.

Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis

Margo Tuerlings, Marcella van Hoolwerff, Jessica M van Bokkum, H Eka D Suchiman, Nico Lakenberg, Demiën Broekhuis, Rob G H H Nelissen, Yolande F M Ramos, Hailiang Mei, Davy Cats, Rodrigo Coutinho de Almeida, Ingrid Meulenbelt

Rheumatology (Oxford) 2022 Jul; 61(7): 3023–3032. Published online 2021 Nov 3. doi: 10.1093/rheumatology/keab826

PMCID:: PMC9258540

Abstract Article PDF–907K

Select item 60867562.

Decreased Local and Systemic Levels of sFRP3 protein in Osteosarcoma Patients

Dalibel Bravo, Ahmet Salduz, Kristen L. Shogren, Madison N. Okuno, James L. Herrick, Scott H. Okuno, Mario Galindo, Andre J. van Wijnen, Michael J. Yaszemski, Avudaiappan Maran

Gene. Author manuscript; available in PMC 2019 Oct 20.

Published in final edited form as: Gene. 2018 Oct 20; 674: 1–7. Published online 2018 Jun 19. doi: 10.1016/j.gene.2018.06.059

PMCID:: PMC6086756

Abstract Article PDF–598K

Select item 48380703.

Expression patterns of Wnt signaling component, secreted frizzled-related protein 3 in astrocytoma and glioblastoma

NIVES PEĆINA-ŠLAUS, ANJA KAFKA, ANA MARIA VAROŠANEC, LEON MARKOVIĆ, ŽELJKA KRSNIK, NIKO NJIRIĆ, GORAN MRAK

Mol Med Rep. 2016 May; 13(5): 4245–4251. Published online 2016 Mar 28. doi: 10.3892/mmr.2016.5061

PMCID:: PMC4838070

Abstract Article PDF–817K

Select item 46804854.

FRZB up-regulated in hepatocellular carcinoma bone metastasis

Jia Huang, Wenhao Hu, Xiangjin Lin, Xuanwei Wang, Ketao Jin

Int J Clin Exp Pathol. 2015; 8(10): 13353–13359. Published online 2015 Oct 1.

PMCID:: PMC4680485

Abstract Article PDF–749K

Select item 45458315.

Secreted Frizzled Related Protein 3 in Chronic Heart Failure: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)

Erik Tandberg Askevold, Lars Gullestad, Ståle Nymo, John Kjekshus, Arne Yndestad, Roberto Latini, John G. F. Cleland, John J. V. McMurray, Pål Aukrust, Thor Ueland

PLoS One. 2015; 10(8): e0133970. Published online 2015 Aug 19. doi: 10.1371/journal.pone.0133970

PMCID:: PMC4545831

Abstract Article PDF–1.2M

Select item 44669836.

FRZB up-regulation is correlated with hepatic metastasis and poor prognosis in colon carcinoma patients with hepatic metastasis

Yanping Shen, Fang Zhang, Huanrong Lan, Ke Chen, Qi Zhang, Guoming Xie, Lisong Teng, Ketao Jin

Int J Clin Exp Pathol. 2015; 8(4): 4083–4090. Published online 2015 Apr 1.

PMCID:: PMC4466983

Abstract Article PDF–817K

Select item 39256107.

Promoter Methylation of SFRP3 Is Frequent in Hepatocellular Carcinoma

Ya-Wen Lin, Yu-Lueng Shih, Gi-Shih Lien, Fat-Moon Suk, Chung-Bao Hsieh, Ming-De Yan

Dis Markers. 2014; 2014: 351863. Published online 2014 Jan 21. doi: 10.1155/2014/351863

PMCID:: PMC3925610

Abstract Article PDF–1.0M

Select item 33404428.

Variant Alleles of the WNT Antagonist FRZB Are Determinants of Hip Shape and Modify the Relationship between Hip Shape and Osteoarthritis

Julie C. Baker-LePain, John A. Lynch, Neeta Parimi, Charles E. McCulloch, Michael C. Nevitt, Maripat Corr, Nancy E. Lane

Arthritis Rheum. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Arthritis Rheum. 2012 May; 64(5): 1457–1465. doi: 10.1002/art.34526

PMCID:: PMC3340442

Abstract Article PDF–1.3M

Select item 30729809.

Methylation and Loss of Secreted Frizzled-Related Protein 3 Enhances Melanoma Cell Migration and Invasion

Elin J. Ekström, Victoria Sherwood, Tommy Andersson

PLoS One. 2011; 6(4): e18674. Published online 2011 Apr 8. doi: 10.1371/journal.pone.0018674

PMCID:: PMC3072980

Abstract Article PDF–543K

Select item 280624910.

No association of the polymorphisms of the frizzled-related protein gene with peak bone mineral density in Chinese nuclear families

Gao Gao, Zhen-Lin Zhang, Jin-Wei He, Hao Zhang, Hua Yue, Wei-Wei Hu, Jie-Mei Gu, Wen-Zhen Fu, Yun-Qiu Hu, Miao Li, Yu-Juan Liu, Jin-Bo Yu

BMC Med Genet. 2010; 11: 1. Published online 2010 Jan 1. doi: 10.1186/1471-2350-11-1

PMCID:: PMC2806249

Abstract Article PDF–244K

Select item 266720711.

Genetic variants in frizzled-related protein (FRZB) and the risk of colorectal neoplasia

Sonja I. Berndt, Wen-Yi Huang, Meredith Yeager, Joel L. Weissfeld, Stephen J. Chanock, Richard B. Hayes

Cancer Causes Control. Author manuscript; available in PMC 2009 Nov 1.

Published in final edited form as: Cancer Causes Control. 2009 May; 20(4): 487–490. Published online 2008 Dec 9. doi: 10.1007/s10552-008-9274-y

PMCID:: PMC2667207

Abstract Article PDF–292K

Select item 195469612.

Further evidence of the role of frizzled‐related protein gene polymorphisms in osteoarthritis

J Rodriguez‐Lopez, M Pombo‐Suarez, M Liz, JJ Gomez‐Reino, A Gonzalez

Ann Rheum Dis. 2007 Aug; 66(8): 1052–1055. Published online 2007 Jan 19. doi: 10.1136/ard.2006.065938

PMCID:: PMC1954696

Abstract Article PDF–115K

Select item 47074713.

Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females

John Loughlin, Barbara Dowling, Kay Chapman, Lucy Marcelline, Zehra Mustafa, Lorraine Southam, Athena Ferreira, Cathleen Ciesielski, Dennis A. Carson, Maripat Corr

Proc Natl Acad Sci U S A. 2004 Jun 29; 101(26): 9757–9762. Published online 2004 Jun 21. doi: 10.1073/pnas.0403456101

PMCID:: PMC470747

Abstract Article PDF–353K

Select item 1083496114.

WTAP-mediated m⁶A modification of FRZB triggers the inflammatory response via the Wnt signaling pathway in osteoarthritis

Xueying An, Rongliang Wang, Zhongyang Lv, Wenshu Wu, Ziying Sun, Rui Wu, Wenjin Yan, Qing Jiang, Xingquan Xu

Exp Mol Med. 2024 Feb; 56(1): 156–167. Published online 2024 Jan 4. doi: 10.1038/s12276-023-01135-5

PMCID:: PMC10834961

Abstract Article PDF–8.9M

Select item 846116115.

The Expressions of Dickkopf-Related Protein 1 and Frizzled-Related Protein Are Negatively Correlated to Local Inflammation and Osteoarthritis Severity

Xiaobin Huang, Leilei Zhong, Eefje van Helvoort, Floris Lafeber, Simon Mastbergen, Jan Hendriks, Janine N. Post, Marcel Karperien

Cartilage. 2021 Oct; 12(4): 496–504. Published online 2019 Apr 4. doi: 10.1177/1947603519841676

PMCID:: PMC8461161

Abstract Article PDF–815K

Select item 512473716.

Endogenous DKK1 and FRZB Regulate Chondrogenesis and Hypertrophy in Three-Dimensional Cultures of Human Chondrocytes and Human Mesenchymal Stem Cells

Leilei Zhong, Xiaobin Huang, Emilie Dooms Rodrigues, Jeroen C.H. Leijten, Theo Verrips, Mohamed El Khattabi, Marcel Karperien, Janine N. Post

Stem Cells Dev. 2016 Dec 1; 25(23): 1808–1817. Published online 2016 Dec 1. doi: 10.1089/scd.2016.0222

PMCID:: PMC5124737

Abstract Article PDF–828K

Select item 441288517.

Large-Scale Analysis of Association Between GDF5 and FRZB Variants and Osteoarthritis of the Hip, Knee, and Hand

Evangelos Evangelou, Kay Chapman, Ingrid Meulenbelt, Fotini B. Karassa, John Loughlin, Andrew Carr, Michael Doherty, Sally Doherty, Juan J. Gómez-Reino, Antonio Gonzalez, Bjarni V. Halldorsson, Valdimar B. Hauksson, Albert Hofman, Deborah J. Hart, Shiro Ikegawa, Thorvaldur Ingvarsson, Qing Jiang, Ingileif Jonsdottir, Helgi Jonsson, Hanneke J. M. Kerkhof, Margreet Kloppenburg, Nancy E. Lane, Jia Li, Rik J. Lories, Joyce B. J. van Meurs, Annu Näkki, Michael C. Nevitt, Julio Rodriguez-Lopez, Dongquan Shi, P. Eline Slagboom, Kari Stefansson, Aspasia Tsezou, Gillian A. Wallis, Christopher M. Watson, Tim D. Spector, Andre G. Uitterlinden, Ana M. Valdes, John P. A. Ioannidis

Arthritis Rheum. Author manuscript; available in PMC 2015 Apr 29.

Published in final edited form as: Arthritis Rheum. 2009 Jun; 60(6): 1710–1721. doi: 10.1002/art.24524

PMCID:: PMC4412885

Abstract Article PDF–656K

Select item 397072918.

Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice and humans

M-H Jang, Y Kitabatake, E Kang, H Jun, MV Pletnikov, KM Christian, R Hen, S Lucae, EB Binder, H Song, G-I Ming

Mol Psychiatry. Author manuscript; available in PMC 2014 Mar 31.

Published in final edited form as: Mol Psychiatry. 2013 Sep; 18(9): 957–958. Published online 2012 Dec 4. doi: 10.1038/mp.2012.158

PMCID:: PMC3970729

Article PDF–599K

Select item 377326819.

Novel membrane frizzled-related protein (MFRP) gene mutation as cause of posterior microphthalmia resulting in high hyperopia with macular folds

Rosemarie A. Wasmann, Jolien S. Klein Wassink-Ruiter, Olof H. Sundin, Elisa Morales, Joke B.G.M. Verheij, Jan-Willem R. Pott

Acta Ophthalmol. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Acta Ophthalmol. 2014 May; 92(3): 276–281. Published online 2013 Jun 7. doi: 10.1111/aos.12105

PMCID:: PMC3773268

Abstract Article PDF–1.0M

Select item 282424520.

Frzb, a Secreted Wnt Antagonist, Decreases Growth and Invasiveness of Fibrosarcoma Cells Associated with Inhibition of Met Signaling

Yi Guo, Jun Xie, Elyssa Rubin, Ya-Xiong Tang, Fritz Lin, Xiaolin Zi, Bang H. Hoang

Cancer Res. Author manuscript; available in PMC 2010 Feb 18.

Published in final edited form as: Cancer Res. 2008 May 1; 68(9): 3350–3360. doi: 10.1158/0008-5472.CAN-07-3220

PMCID:: PMC2824245

Abstract Article PDF–3.2M

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