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Select item 112456861.

Cancer EV stimulate endothelial glycolysis to fuel protein synthesis via mTOR and AMPKα activation

Joël E. J. Beaumont, Lydie M. O. Barbeau, Jinzhe Ju, Kim G. Savelkouls, Freek G. Bouwman, Marijke I. Zonneveld, Annelies Bronckaers, Kim R. Kampen, Tom G. H. Keulers, Kasper M. A. Rouschop

J Extracell Vesicles. 2024 Jul; 13(7): e12449. Published online 2024 Jul 13. doi: 10.1002/jev2.12449

PMCID:: PMC11245686

Abstract Article PDF–5.5M

Select item 111146912.

Regulatory T cells, mTOR kinase, and metabolic activity

Claudio Procaccini, Giuseppe Matarese

Cell Mol Life Sci. 2012 Dec; 69(23): 3975–3987. Published online 2012 Jul 4. doi: 10.1007/s00018-012-1058-6

PMCID:: PMC11114691

Abstract Article PDF–328K

Select item 109316423.

mTOR Signaling: Recent Progress

Antonios N. Gargalionis, Kostas A. Papavassiliou, Athanasios G. Papavassiliou

Int J Mol Sci. 2024 Mar; 25(5): 2587. Published online 2024 Feb 23. doi: 10.3390/ijms25052587

PMCID:: PMC10931642

Article PDF–177K

Select item 108961814.

Malignant Brain Aging: The Formidable Link Between Dysregulated Signaling Through Mechanistic Target of Rapamycin Pathways and Alzheimer’s Disease (Type 3 Diabetes)

Suzanne M. de la Monte

J Alzheimers Dis. Author manuscript; available in PMC 2024 Feb 26.

Published in final edited form as: J Alzheimers Dis. 2023; 95(4): 1301–1337. doi: 10.3233/JAD-230555

PMCID:: PMC10896181

Abstract Article PDF–522K

Select item 108780355.

Human cytomegalovirus modulates mTORC1 to redirect mRNA translation within quiescently infected monocytes

Michael J. Miller, Dilruba Akter, Jamil Mahmud, Gary C. Chan

J Virol. 2024 Feb; 98(2): e01888-23. Published online 2024 Jan 30. doi: 10.1128/jvi.01888-23

PMCID:: PMC10878035

Abstract Article PDF–3.6M

Select item 108438056.

Mechanistic target of rapamycin in regulating macrophage function in inflammatory cardiovascular diseases

MariaSanta C. Mangione, Jinhua Wen, Dian J. Cao

J Mol Cell Cardiol. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: J Mol Cell Cardiol. 2024 Jan; 186: 111–124. Published online 2023 Nov 30. doi: 10.1016/j.yjmcc.2023.10.011

PMCID:: PMC10843805

Abstract Article PDF–964K

Select item 106951807.

mTOR pathway candidate genes and obesity interaction on breast cancer risk in Black women from the Women’s Circle of Health Study

Mmadili N. Ilozumba, Lusine Yaghjyan, Susmita Datta, Jinying Zhao, Chi-Chen Hong, Kathryn L. Lunetta, Gary Zirpoli, Elisa V. Bandera, Julie R. Palmer, Song Yao, Christine B. Ambrosone, Ting-Yuan David Cheng

Cancer Causes Control. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Cancer Causes Control. 2023 May; 34(5): 431–447. Published online 2023 Feb 15. doi: 10.1007/s10552-022-01657-9

PMCID:: PMC10695180

Abstract Article PDF–737K

Select item 106339478.

Deep histopathology genotype–phenotype analysis of focal cortical dysplasia type II differentiates between the GATOR1-altered autophagocytic subtype IIa and MTOR-altered migration deficient subtype IIb

Jonas Honke, Lucas Hoffmann, Roland Coras, Katja Kobow, Costin Leu, Tom Pieper, Till Hartlieb, Christian G. Bien, Friedrich Woermann, Thomas Cloppenborg, Thilo Kalbhenn, Ahmed Gaballa, Hajo Hamer, Sebastian Brandner, Karl Rössler, Arnd Dörfler, Stefan Rampp, Johannes R. Lemke, Sara Baldassari, Stéphanie Baulac, Dennis Lal, Peter Nürnberg, Ingmar Blümcke

Acta Neuropathol Commun. 2023; 11: 179. Published online 2023 Nov 9. doi: 10.1186/s40478-023-01675-x

PMCID:: PMC10633947

Abstract Article PDF–1.9M

Select item 106063419.

Signaling Pathways mTOR and ERK as Therapeutic Targets in Sinonasal Intestinal-Type Adenocarcinoma

Helena Codina-Martínez, Sara Lucila Lorenzo-Guerra, Virginia N. Cabal, Rocío García-Marín, Laura Suárez-Fernández, Blanca Vivanco, Paula Sánchez-Fernández, Fernando López, José Luis Llorente, Mario A. Hermsen

Int J Mol Sci. 2023 Oct; 24(20): 15110. Published online 2023 Oct 12. doi: 10.3390/ijms242015110

PMCID:: PMC10606341

Abstract Article PDF–1.5M

Select item 1045412110.

Signaling Pathways Leading to mTOR Activation Downstream Cytokine Receptors in Lymphocytes in Health and Disease

Lucie Fallone, Thierry Walzer, Antoine Marçais

Int J Mol Sci. 2023 Aug; 24(16): 12736. Published online 2023 Aug 13. doi: 10.3390/ijms241612736

PMCID:: PMC10454121

Abstract Article PDF–2.0M

Select item 1045300811.

Metabolic Disruption Induced by mTOR Signaling Pathway Inhibition in Regulatory T-Cell Expansion for Clinical Application

Roberto Gedaly, Gabriel Orozco, Alexandre P. Ancheta, Mackenzie Donoho, Siddharth N. Desai, Fanny Chapelin, Aman Khurana, Lillie J. Lewis, Cuiping Zhang, Francesc Marti

Cells. 2023 Aug; 12(16): 2066. Published online 2023 Aug 15. doi: 10.3390/cells12162066

PMCID:: PMC10453008

Abstract Article PDF–3.2M

Select item 1038053212.

mTOR Signaling Pathway and Gut Microbiota in Various Disorders: Mechanisms and Potential Drugs in Pharmacotherapy

Yuan Gao, Tian Tian

Int J Mol Sci. 2023 Jul; 24(14): 11811. Published online 2023 Jul 22. doi: 10.3390/ijms241411811

PMCID:: PMC10380532

Abstract Article PDF–1.6M

Select item 1027554213.

Advances in the mTOR signaling pathway and its inhibitor rapamycin in epilepsy

Wei Zhao, Cong Xie, Xu Zhang, Ju Liu, Jinzhi Liu, Zhangyong Xia

Brain Behav. 2023 Jun; 13(6): e2995. Published online 2023 May 23. doi: 10.1002/brb3.2995

PMCID:: PMC10275542

Abstract Article PDF–469K

Select item 1026275414.

Membrane Atg8ylation, stress granule formation, and MTOR regulation during lysosomal damage

Jingyue Jia, Fulong Wang, Zambarlal Bhujabal, Ryan Peters, Michal Mudd, Thabata Duque, Lee Allers, Ruheena Javed, Michelle Salemi, Christian Behrends, Brett Phinney, Terje Johansen, Vojo Deretic

Autophagy. 2023; 19(6): 1893–1895. Published online 2022 Nov 29. doi: 10.1080/15548627.2022.2148900

PMCID:: PMC10262754

Abstract Article PDF–458K

Select item 1024019815.

Low temperature and mTOR inhibition favor stem cell maintenance in human keratinocyte cultures

Daisuke Nanba, Jun‐Ichi Sakabe, Johannes Mosig, Michel Brouard, Fujio Toki, Mariko Shimokawa, Mako Kamiya, Thomas Braschler, Fahd Azzabi, Stéphanie Droz‐Georget Lathion, Kai Johnsson, Keya Roy, Christoph D Schmid, Jean‐Baptiste Bureau, Ariane Rochat, Yann Barrandon

EMBO Rep. 2023 Jun; 24(6): e55439. Published online 2023 May 4. doi: 10.15252/embr.202255439

PMCID:: PMC10240198

Abstract Article PDF–5.1M

Select item 1020790916.

Overexpression of mTOR in Leukocytes from ALS8 Patients

Nathália Augusta Gomes, Francisco das Chagas Lima e Silva, Caroline Maria de Oliveira Volpe, Pedro Henrique Villar-Delfino, Camila Ferreira de Sousa, Fabiana Rocha-Silva, José Augusto Nogueira-Machado

Curr Neuropharmacol. 2023 Mar 8; 21(3): 482–490. Published online 2023 Mar 8. doi: 10.2174/1570159X21666230201151016

PMCID:: PMC10207909

Abstract Article PDF–3.5M

Select item 1017767617.

Echinococcus multilocularis protoscoleces enhance glycolysis to promote M2 Macrophages through PI3K/Akt/mTOR Signaling Pathway

Tao Zhang, Yaogang Zhang, Zihan Yang, Yuan Jiang, Li Sun, Dengliang Huang, Meiyuan Tian, Yinhong Shen, Jun Deng, Jing Hou, Yanyan Ma

Pathog Glob Health. 2023; 117(4): 409–416. Published online 2022 Jul 25. doi: 10.1080/20477724.2022.2104055

PMCID:: PMC10177676

Abstract Article PDF–7.8M

Select item 1015045318.

The effects of acute aerobic and resistance exercise on mTOR signaling and autophagy markers in untrained human skeletal muscle

Corey E. Mazo, Andrew C. D’Lugos, Kaylin R. Sweeney, Jacob M. Haus, Siddhartha S. Angadi, Chad C. Carroll, Jared M. Dickinson

Eur J Appl Physiol. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Eur J Appl Physiol. 2021 Oct; 121(10): 2913–2924. Published online 2021 Jul 1. doi: 10.1007/s00421-021-04758-6

PMCID:: PMC10150453

Abstract Article PDF–1.0M

Select item 999052519.

Association Between Recreational Physical Activity and mTOR Signaling Pathway Protein Expression in Breast Tumor Tissue

Ting-Yuan David Cheng, Runzhi Zhang, Zhihong Gong, Bo Qin, Rikki A. Cannioto, Susmita Datta, Weizhou Zhang, Angela R. Omilian, Song Yao, Thaer Khoury, Chi-Chen Hong, Elisa V. Bandera, Christine B. Ambrosone

Cancer Res Commun. 2023 Mar; 3(3): 395–403. Published online 2023 Mar 7. doi: 10.1158/2767-9764.CRC-22-0405

PMCID:: PMC9990525

Abstract Article PDF–2.4M

Select item 992846320.

Mechanistic target of rapamycin (mTOR) regulates self-sustained quiescence, tumor indolence, and late clinical metastasis in a Beclin-1-dependent manner

Carole Nicco, Marine Thomas, Julie Guillermet, Maryline Havard, Fanny Laurent-Tchenio, Ludivine Doridot, François Dautry, Frédéric Batteux, Thierry Tchenio

Cell Cycle. 2023; 22(5): 542–564. Published online 2022 Sep 19. doi: 10.1080/15384101.2022.2123187

PMCID:: PMC9928463

Abstract Article PDF–5.6M

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PMC Links for Gene (Select 2475) (1344)
PMC
GAP Links for Gene (Select 2475) (7)
dbGaP
protein transport protein Sec31A isoform 28 [Homo sapiens]
protein transport protein Sec31A isoform 28 [Homo sapiens]
gi|2181405700|ref|NP_001387147.1|

Protein
Homo sapiens SEC31 homolog A, COPII coat complex component (SEC31A), transcript ...
Homo sapiens SEC31 homolog A, COPII coat complex component (SEC31A), transcript variant 16, mRNA
gi|2181405434|ref|NM_001400159.1|

Nucleotide
protein transport protein Sec31A isoform 17 [Homo sapiens]
protein transport protein Sec31A isoform 17 [Homo sapiens]
gi|2181405684|ref|NP_001387115.1|

Protein

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