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Items: 1 to 20 of 41

1.
RNase H1 facilitates recombinase recruitment by degrading DNA–RNA hybrids during meiosis
Chao Liu, Liying Wang, Yanan Li, Mengmeng Guo, Jun Hu, Teng Wang, Mengjing Li, Zhuo Yang, Ruoyao Lin, Wei Xu, Yinghong Chen, Mengcheng Luo, Fei Gao, Jia-Yu Chen, Qianwen Sun, Hongbin Liu, Bo Sun, Wei Li
Nucleic Acids Res. 2023 Aug 11; 51(14): 7357–7375. Published online 2023 Jun 28. doi: 10.1093/nar/gkad524
PMCID:
PMC10415156
AbstractArticlePDF–5.4M
2.
RNase H1 directs origin-specific initiation of DNA replication in human mitochondria
Viktor Posse, Ali Al-Behadili, Jay P. Uhler, Anders R. Clausen, Aurelio Reyes, Massimo Zeviani, Maria Falkenberg, Claes M. Gustafsson
PLoS Genet. 2019 Jan; 15(1): e1007781. Published online 2019 Jan 3. doi: 10.1371/journal.pgen.1007781
PMCID:
PMC6317783
AbstractArticlePDF–2.1M
3.
Pathological ribonuclease H1 causes R-loop depletion and aberrant DNA segregation in mitochondria
Gokhan Akman, Radha Desai, Laura J. Bailey, Takehiro Yasukawa, Ilaria Dalla Rosa, Romina Durigon, J. Bradley Holmes, Chloe F. Moss, Mara Mennuni, Henry Houlden, Robert J. Crouch, Michael G. Hanna, Robert D. S. Pitceathly, Antonella Spinazzola, Ian J. Holt
Proc Natl Acad Sci U S A. 2016 Jul 26; 113(30): E4276–E4285. Published online 2016 Jul 8. doi: 10.1073/pnas.1600537113
PMCID:
PMC4968715
AbstractArticlePDF–2.2M
4.
RNASEH1 Mutations Impair mtDNA Replication and Cause Adult-Onset Mitochondrial Encephalomyopathy
Aurelio Reyes, Laura Melchionda, Alessia Nasca, Franco Carrara, Eleonora Lamantea, Alice Zanolini, Costanza Lamperti, Mingyan Fang, Jianguo Zhang, Dario Ronchi, Sara Bonato, Gigliola Fagiolari, Maurizio Moggio, Daniele Ghezzi, Massimo Zeviani
Am J Hum Genet. 2015 Jul 2; 97(1): 186–193. doi: 10.1016/j.ajhg.2015.05.013
PMCID:
PMC4572567
AbstractArticlePDF–2.3M
5.
RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells
Rajika Arora, Yongwoo Lee, Harry Wischnewski, Catherine M. Brun, Tobias Schwarz, Claus M. Azzalin
Nat Commun. 2014 Oct 21; 5: 5220. Published online 2014 Oct 21. doi: 10.1038/ncomms6220
PMCID:
PMC4218956
AbstractArticlePDF–3.9M
6.
Evidence for a Dual Functional Role of a Conserved Histidine in RNA•DNA Heteroduplex Cleavage by Human RNase H1
Nageswara R. Alla, Allen W. Nicholson
FEBS J. Author manuscript; available in PMC 2013 Dec 1.
Published in final edited form as: FEBS J. 2012 Dec; 279(24): 4492–4500. Published online 2012 Nov 9. doi: 10.1111/febs.12035
PMCID:
PMC3515698
AbstractArticlePDF–742K
7.
Structural Basis of the RNase H1 Activity on Stereo Regular Borano Phosphonate DNA/RNA Hybrids
Christopher N Johnson, Alexander M. Spring, Barbara R. Shaw, Markus W. Germann
Biochemistry. Author manuscript; available in PMC 2012 May 17.
Published in final edited form as: Biochemistry. 2011 May 17; 50(19): 3903–3912. Published online 2011 Apr 19. doi: 10.1021/bi200083d
PMCID:
PMC3098115
AbstractArticlePDF–1.5M
8.
Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD
Marcin Nowotny, Susana M Cerritelli, Rodolfo Ghirlando, Sergei A Gaidamakov, Robert J Crouch, Wei Yang
EMBO J. 2008 Apr 9; 27(7): 1172–1181. Published online 2008 Mar 13. doi: 10.1038/emboj.2008.44
PMCID:
PMC2323259
AbstractArticlePDF–459K
9.
BRCA2 deficiency reveals that oxidative stress impairs RNaseH1 function to cripple mitochondrial DNA maintenance
Xavier Renaudin, Miyoung Lee, Mona Shehata, Eva-Maria Surmann, Ashok R. Venkitaraman
Cell Rep. 2021 Aug 3; 36(5): 109478. Published online 2021 Aug 3. doi: 10.1016/j.celrep.2021.109478
PMCID:
PMC8356021
AbstractArticle
10.
Kinetic and subcellular analysis of PS-ASO/protein interactions with P54nrb and RNase H1
Timothy A Vickers, Meghdad Rahdar, Thazha P Prakash, Stanley T Crooke
Nucleic Acids Res. 2019 Nov 18; 47(20): 10865–10880. Published online 2019 Sep 9. doi: 10.1093/nar/gkz771
PMCID:
PMC6846478
AbstractArticlePDF–6.0M
11.
A two-nuclease pathway involving RNase H1 is required for primer removal at human mitochondrial OriL
Ali Al-Behadili, Jay P Uhler, Anna-Karin Berglund, Bradley Peter, Mara Doimo, Aurelio Reyes, Sjoerd Wanrooij, Massimo Zeviani, Maria Falkenberg
Nucleic Acids Res. 2018 Oct 12; 46(18): 9471–9483. Published online 2018 Aug 8. doi: 10.1093/nar/gky708
PMCID:
PMC6182146
AbstractArticlePDF–4.3M
12.
Human ribonuclease H1 resolves R-loops and thereby enables progression of the DNA replication fork
Shankar Parajuli, Daniel C. Teasley, Bhavna Murali, Jessica Jackson, Alessandro Vindigni, Sheila A. Stewart
J Biol Chem. 2017 Sep 15; 292(37): 15216–15224. Published online 2017 Jul 17. doi: 10.1074/jbc.M117.787473
PMCID:
PMC5602383
AbstractArticlePDF–1.1M
13.
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
Hai Dang Nguyen, Tribhuwan Yadav, Sumanprava Giri, Borja Saez, Timothy A. Graubert, Lee Zou
Mol Cell. Author manuscript; available in PMC 2017 Jul 12.
Published in final edited form as: Mol Cell. 2017 Mar 2; 65(5): 832–847.e4. doi: 10.1016/j.molcel.2017.01.029
PMCID:
PMC5507214
AbstractArticlePDF–1.9M
14.
Human RNase H1 Is Associated with Protein P32 and Is Involved in Mitochondrial Pre-rRNA Processing
Hongjiang Wu, Hong Sun, Xuehai Liang, Walt F. Lima, Stanley T. Crooke
PLoS One. 2013; 8(8): e71006. Published online 2013 Aug 22. doi: 10.1371/journal.pone.0071006
PMCID:
PMC3750045
AbstractArticlePDF–6.1M
15.
Progressive External Ophthalmoplegia in Polish Patients—From Clinical Evaluation to Genetic Confirmation
Biruta Kierdaszuk, Magdalena Kaliszewska, Joanna Rusecka, Joanna Kosińska, Ewa Bartnik, Katarzyna Tońska, Anna M. Kamińska, Anna Kostera-Pruszczyk
Genes (Basel) 2021 Jan; 12(1): 54. Published online 2020 Dec 31. doi: 10.3390/genes12010054
PMCID:
PMC7824435
AbstractArticlePDF–4.8M
16.
RNase H sequence preferences influence antisense oligonucleotide efficiency
Łukasz J. Kiełpiński, Peter H. Hagedorn, Morten Lindow, Jeppe Vinther
Nucleic Acids Res. 2017 Dec 15; 45(22): 12932–12944. Published online 2017 Nov 8. doi: 10.1093/nar/gkx1073
Expression of Concern in:
Nucleic Acids Res. 2019 Mar 18; 47(5): 2701.
PMCID:
PMC5728404
AbstractArticlePDF–1.4M
17.
An Upstream Open Reading Frame and the Context of the Two AUG Codons Affect the Abundance of Mitochondrial and Nuclear RNase H1
Yutaka Suzuki, J. Bradley Holmes, Susana M. Cerritelli, Kiran Sakhuja, Michal Minczuk, Ian J. Holt, Robert J. Crouch
Mol Cell Biol. 2010 Nov; 30(21): 5123–5134. Published online 2010 Sep 7. doi: 10.1128/MCB.00619-10
PMCID:
PMC2953059
AbstractArticlePDF–2.5M
18.
Ribonuclease H: the enzymes in Eukaryotes
Susana M. Cerritelli, Robert J. Crouch
FEBS J. Author manuscript; available in PMC 2010 Mar 1.
Published in final edited form as: FEBS J. 2009 Mar; 276(6): 1494–1505. Published online 2008 Feb 18. doi: 10.1111/j.1742-4658.2009.06908.x
PMCID:
PMC2746905
AbstractArticlePDF–905K
19.
Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination
Konstantina Skourti-Stathaki, Nicholas J. Proudfoot, Natalia Gromak
Mol Cell. 2011 Jun 24; 42(6): 794–805. doi: 10.1016/j.molcel.2011.04.026
PMCID:
PMC3145960
AbstractArticle
20.
Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing
Wenyi Wang, Peidong Shen, Sreedevi Thiyagarajan, Shengrong Lin, Curtis Palm, Rita Horvath, Thomas Klopstock, David Cutler, Lynn Pique, Iris Schrijver, Ronald W. Davis, Michael Mindrinos, Terence P. Speed, Curt Scharfe
Nucleic Acids Res. 2011 Jan; 39(1): 44–58. Published online 2010 Sep 15. doi: 10.1093/nar/gkq750
PMCID:
PMC3017602
AbstractArticlePDF–1.4M

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