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Items: 1 to 20 of 34

1.
Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity
Hui Wang, Masahiro Morita, Xiuna Yang, Toru Suzuki, Wen Yang, Jiao Wang, Kentaro Ito, Quan Wang, Cong Zhao, Mark Bartlam, Tadashi Yamamoto, Zihe Rao
EMBO J. 2010 Aug 4; 29(15): 2566–2576. Published online 2010 Jul 13. doi: 10.1038/emboj.2010.152
PMCID:
PMC2928688
AbstractArticlePDF–1.5M
2.
1‐Hydroxy‐xanthine derivatives inhibit the human Caf1 nuclease and Caf1‐containing nuclease complexes via Mg2+‐dependent binding
Blessing Airhihen, Lorenzo Pavanello, Gopal P. Jadhav, Peter M. Fischer, Gerlof Sebastiaan Winkler
FEBS Open Bio. 2019 Apr; 9(4): 717–727. Published online 2019 Mar 7. doi: 10.1002/2211-5463.12605
PMCID:
PMC6443996
AbstractArticlePDF–903K
3.
mRNA levels are buffered upon knockdown of RNA decay and translation factors via adjustment of transcription rates in human HepG2 cells
Pavneet Singh, Rob S. James, Christopher J Mee, Igor Y. Morozov
RNA Biol. 2019 Sep; 16(9): 1147–1155. Published online 2019 May 31. doi: 10.1080/15476286.2019.1621121
PMCID:
PMC6693547
AbstractArticlePDF–2.5M
4.
Hepatic posttranscriptional network comprised of CCR4–NOT deadenylase and FGF21 maintains systemic metabolic homeostasis
Masahiro Morita, Nadeem Siddiqui, Sakie Katsumura, Christopher Rouya, Ola Larsson, Takeshi Nagashima, Bahareh Hekmatnejad, Akinori Takahashi, Hiroshi Kiyonari, Mengwei Zang, René St-Arnaud, Yuichi Oike, Vincent Giguère, Ivan Topisirovic, Mariko Okada-Hatakeyama, Tadashi Yamamoto, Nahum Sonenberg
Proc Natl Acad Sci U S A. 2019 Apr 16; 116(16): 7973–7981. Published online 2019 Mar 29. doi: 10.1073/pnas.1816023116
PMCID:
PMC6475422
AbstractArticlePDF–1.8M
5.
The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4–Not complex contribute to the prevention of cell death and senescence
Saloni Mittal, Akhmed Aslam, Rachel Doidge, Rachel Medica, G. Sebastiaan Winkler
Mol Biol Cell. 2011 Mar 15; 22(6): 748–758. doi: 10.1091/mbc.E10-11-0898
PMCID:
PMC3057700
AbstractArticlePDF–2.4M
6.
A Bayesian approach to genetic association studies with family-based designs
Melissa G. Naylor, Scott T. Weiss, Christoph Lange
Genet Epidemiol. Author manuscript; available in PMC 2012 May 11.
Published in final edited form as: Genet Epidemiol. 2010 Sep; 34(6): 569–574. doi: 10.1002/gepi.20513
PMCID:
PMC3349938
AbstractArticlePDF–620K
7.
Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure
Sakie Katsumura, Nadeem Siddiqui, Michael Rock Goldsmith, Jaime H. Cheah, Teppei Fujikawa, Genki Minegishi, Atsushi Yamagata, Yukako Yabuki, Kaoru Kobayashi, Mikako Shirouzu, Takeshi Inagaki, Tim H.-M. Huang, Nicolas Musi, Ivan Topisirovic, Ola Larsson, Masahiro Morita
Cell Metab. Author manuscript; available in PMC 2023 Apr 5.
Published in final edited form as: Cell Metab. 2022 Apr 5; 34(4): 564–580.e8. doi: 10.1016/j.cmet.2022.03.005
PMCID:
PMC9386786
AbstractArticlePDF–4.3M
8.
Phosphorylation of Tristetraprolin by MK2 Impairs AU-Rich Element mRNA Decay by Preventing Deadenylase Recruitment
Sandra L. Clement, Claudia Scheckel, Georg Stoecklin, Jens Lykke-Andersen
Mol Cell Biol. 2011 Jan; 31(2): 256–266. Published online 2010 Nov 15. doi: 10.1128/MCB.00717-10
PMCID:
PMC3019984
AbstractArticlePDF–1.2M
9.
The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4–NOT deadenylase complex
Alain-Pierre Petit, Lara Wohlbold, Praveen Bawankar, Eric Huntzinger, Steffen Schmidt, Elisa Izaurralde, Oliver Weichenrieder
Nucleic Acids Res. 2012 Nov; 40(21): 11058–11072. Published online 2012 Sep 12. doi: 10.1093/nar/gks883
PMCID:
PMC3510486
AbstractArticlePDF–6.5M
10.
Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation
Tobias Raisch, Chung-Te Chang, Yevgen Levdansky, Sowndarya Muthukumar, Stefan Raunser, Eugene Valkov
Nat Commun. 2019; 10: 3173. Published online 2019 Jul 18. doi: 10.1038/s41467-019-11094-z
PMCID:
PMC6639331
AbstractArticlePDF–3.8M
11.
Depletion of Mammalian CCR4b Deadenylase Triggers Elevation of the p27Kip1 mRNA Level and Impairs Cell Growth
Masahiro Morita, Toru Suzuki, Takahisa Nakamura, Kazumasa Yokoyama, Takashi Miyasaka, Tadashi Yamamoto
Mol Cell Biol. 2007 Jul; 27(13): 4980–4990. Published online 2007 Apr 23. doi: 10.1128/MCB.02304-06
PMCID:
PMC1951489
AbstractArticlePDF–1.1M
12.
RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation
Fabian Poetz, Joshua Corbo, Yevgen Levdansky, Alexander Spiegelhalter, Doris Lindner, Vera Magg, Svetlana Lebedeva, Jörg Schweiggert, Johanna Schott, Eugene Valkov, Georg Stoecklin
Nat Commun. 2021; 12: 7175. Published online 2021 Dec 9. doi: 10.1038/s41467-021-27471-6
PMCID:
PMC8660800
AbstractArticlePDF–5.3M
13.
Genome-wide association study of ancestry-specific TB risk in the South African Coloured population
Emile R. Chimusa, Noah Zaitlen, Michelle Daya, Marlo Möller, Paul D. van Helden, Nicola J. Mulder, Alkes L. Price, Eileen G. Hoal
Hum Mol Genet. 2014 Feb 1; 23(3): 796–809. Published online 2013 Sep 20. doi: 10.1093/hmg/ddt462
PMCID:
PMC3888262
AbstractArticlePDF–560K
14.
Interaction of antiproliferative protein Tob with the CCR4‐NOT deadenylase complex
Takashi Miyasaka, Masahiro Morita, Kentaro Ito, Toru Suzuki, Hiroyuki Fukuda, Shizu Takeda, Jun‐Ichiro Inoue, Kentaro Semba, Tadashi Yamamoto
Cancer Sci. 2008 Apr; 99(4): 755–761. Published online 2008 Mar 28. doi: 10.1111/j.1349-7006.2008.00746.x
PMCID:
PMC11158977
AbstractArticlePDF–210K
15.
RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway
Yasuhiro Murakawa, Michael Hinz, Janina Mothes, Anja Schuetz, Michael Uhl, Emanuel Wyler, Tomoharu Yasuda, Guido Mastrobuoni, Caroline C. Friedel, Lars Dölken, Stefan Kempa, Marc Schmidt-Supprian, Nils Blüthgen, Rolf Backofen, Udo Heinemann, Jana Wolf, Claus Scheidereit, Markus Landthaler
Nat Commun. 2015; 6: 7367. Published online 2015 Jul 14. doi: 10.1038/ncomms8367
PMCID:
PMC4510711
AbstractArticlePDF–3.2M
16.
Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
Bhaskar Saha, Michelle Salemi, Geneva L. Williams, Seeun Oh, Michael L. Paffett, Brett Phinney, Michael A. Mandell
Cell Rep. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110797. doi: 10.1016/j.celrep.2022.110797
PMCID:
PMC9136943
AbstractArticlePDF–3.2M
17.
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity
Yuehui Zhang, Limin Shang, Jing Zhang, Yuchen Liu, Chaozhi Jin, Yanan Zhao, Xiaobo Lei, Wenjing Wang, Xia Xiao, Xiuyuan Zhang, Yujiao Liu, Linlin Liu, Meng-Wei Zhuang, Qingkun Mi, Chunyan Tian, Jianwei Wang, Fuchu He, Pei-Hui Wang, Jian Wang
Cell Chem Biol. 2022 Jan 20; 29(1): 5–18.e6. Published online 2021 Oct 20. doi: 10.1016/j.chembiol.2021.10.008
PMCID:
PMC8527578
AbstractArticlePDF–4.5M
18.
An atlas of combinatorial transcriptional regulation in mouse and man
The FANTOM consortium and RIKEN Omics Science Center
Cell. Author manuscript; available in PMC 2011 Mar 5.
Published in final edited form as: Cell. 2010 Mar 5; 140(5): 744–752. doi: 10.1016/j.cell.2010.01.044
Correction in:
volume 141 on page 369
PMCID:
PMC2836267
AbstractArticlePDF–2.2M
19.
Large-scale mapping of human protein–protein interactions by mass spectrometry
Rob M Ewing, Peter Chu, Fred Elisma, Hongyan Li, Paul Taylor, Shane Climie, Linda McBroom-Cerajewski, Mark D Robinson, Liam O'Connor, Michael Li, Rod Taylor, Moyez Dharsee, Yuen Ho, Adrian Heilbut, Lynda Moore, Shudong Zhang, Olga Ornatsky, Yury V Bukhman, Martin Ethier, Yinglun Sheng, Julian Vasilescu, Mohamed Abu-Farha, Jean-Philippe Lambert, Henry S Duewel, Ian I Stewart, Bonnie Kuehl, Kelly Hogue, Karen Colwill, Katharine Gladwish, Brenda Muskat, Robert Kinach, Sally-Lin Adams, Michael F Moran, Gregg B Morin, Thodoros Topaloglou, Daniel Figeys
Mol Syst Biol. 2007; 3: 89. Published online 2007 Mar 13. doi: 10.1038/msb4100134
PMCID:
PMC1847948
AbstractArticlePDF–440K
20.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
Karsten Boldt, Jeroen van Reeuwijk, Qianhao Lu, Konstantinos Koutroumpas, Thanh-Minh T. Nguyen, Yves Texier, Sylvia E. C. van Beersum, Nicola Horn, Jason R. Willer, Dorus A. Mans, Gerard Dougherty, Ideke J. C. Lamers, Karlien L. M. Coene, Heleen H. Arts, Matthew J. Betts, Tina Beyer, Emine Bolat, Christian Johannes Gloeckner, Khatera Haidari, Lisette Hetterschijt, Daniela Iaconis, Dagan Jenkins, Franziska Klose, Barbara Knapp, Brooke Latour, Stef J. F. Letteboer, Carlo L. Marcelis, Dragana Mitic, Manuela Morleo, Machteld M. Oud, Moniek Riemersma, Susan Rix, Paulien A. Terhal, Grischa Toedt, Teunis J. P. van Dam, Erik de Vrieze, Yasmin Wissinger, Ka Man Wu, Gordana Apic, Philip L. Beales, Oliver E. Blacque, Toby J. Gibson, Martijn A. Huynen, Nicholas Katsanis, Hannie Kremer, Heymut Omran, Erwin van Wijk, Uwe Wolfrum, François Kepes, Erica E. Davis, Brunella Franco, Rachel H. Giles, Marius Ueffing, Robert B. Russell, Ronald Roepman, UK10K Rare Diseases Group
Nat Commun. 2016; 7: 11491. Published online 2016 May 13. doi: 10.1038/ncomms11491
PMCID:
PMC4869170
AbstractArticlePDF–2.0M

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