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Items: 1 to 20 of 74

1.
Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synoviocytes and disrupting chondrocyte homeostasis via Wnt/β-catenin pathway
Dong Guo, Haoyan Pan, Xueying Lu, Zhong Chen, Laixi Zhou, Shuxin Chen, Jin Huang, Xinzhi Liang, Zhisheng Xiao, Hua Zeng, Yan Shao, Weizhong Qi, Denghui Xie, Chuangxin Lin
Arthritis Res Ther. 2023; 25: 217. Published online 2023 Nov 9. doi: 10.1186/s13075-023-03198-1
PMCID:
PMC10634117
AbstractArticlePDF–16M
2.
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 in osteoarthritis
Alexander J. Knights, Easton C. Farrell, Olivia M. Ellis, Lindsey Lammlin, Lucas M. Junginger, Phillip M. Rzeczycki, Rachel F. Bergman, Rida Pervez, Monique Cruz, Eleanor Knight, Dennis Farmer, Alexa A. Samani, Chia-Lung Wu, Kurt D. Hankenson, Tristan Maerz
Ann Rheum Dis. Author manuscript; available in PMC 2023 Feb 28.
Published in final edited form as: Ann Rheum Dis. 2023 Feb; 82(2): 272–282. Published online 2022 Sep 29. doi: 10.1136/ard-2022-222773
PMCID:
PMC9972892
AbstractArticlePDF–4.0M
3.
R-Spondin2, a Positive Canonical WNT Signaling Regulator, Controls the Expansion and Differentiation of Distal Lung Epithelial Stem/Progenitor Cells in Mice
Ahmed A. Raslan, Youn Jeong Oh, Yong Ri Jin, Jeong Kyo Yoon
Int J Mol Sci. 2022 Mar; 23(6): 3089. Published online 2022 Mar 13. doi: 10.3390/ijms23063089
PMCID:
PMC8954098
AbstractArticlePDF–3.9M
4.
DNA methylation mediated RSPO2 to promote follicular development in mammals
Xiaofeng Zhou, Yingting He, Nian Li, Guofeng Bai, Xiangchun Pan, Zhe Zhang, Hao Zhang, Jiaqi Li, Xiaolong Yuan
Cell Death Dis. 2021 Jul; 12(7): 653. Published online 2021 Jun 26. doi: 10.1038/s41419-021-03941-z
PMCID:
PMC8236063
AbstractArticlePDF–4.8M
5.
Rspo2/Int7 Regulates Invasiveness and Tumorigenic Properties of Mammary Epithelial Cells
MALGORZATA KLAUZINSKA, BOLORMAA BALJINNYAM, AHMED RAAFAT, JAIME RODRIGUEZ-CANALES, LUIGI STRIZZI, YOSHIMI ENDO GREER, JEFFREY S. RUBIN, ROBERT CALLAHAN
J Cell Physiol. Author manuscript; available in PMC 2020 Jan 13.
Published in final edited form as: J Cell Physiol. 2012 May; 227(5): 1960–1971. doi: 10.1002/jcp.22924
PMCID:
PMC6957254
AbstractArticlePDF–2.5M
6.
R-Spondin 2 signaling mediates susceptibility to fatal infectious diarrhea
Olivier Papapietro, Sarah Teatero, Ajitha Thanabalasuriar, Kyoko E. Yuki, Eduardo Diez, Lei Zhu, Eugene Kang, Sandeep Dhillon, Aleixo M. Muise, Yves Durocher, Martin M. Marcinkiewicz, Danielle Malo, Samantha Gruenheid
Nat Commun. Author manuscript; available in PMC 2016 Apr 25.
Published in final edited form as: Nat Commun. 2013; 4: 1898. doi: 10.1038/ncomms2816
PMCID:
PMC4844535
AbstractArticlePDF–2.3M
7.
Loss-of-function point mutations and two-furin domain derivatives provide insights about R-spondin2 structure and function
Sheng-Jian Li, Ten-Yang Yen, Yoshimi Endo, Malgorzata Klauzinska, Bolormaa Baljinnyam, Bruce Macher, Robert Callahan, Jeffrey S. Rubin
Cell Signal. Author manuscript; available in PMC 2010 Jun 1.
Published in final edited form as: Cell Signal. 2009 Jun; 21(6): 916. doi: 10.1016/j.cellsig.2009.02.001
PMCID:
PMC2813491
AbstractArticlePDF–1.7M
8.
RSPO2 defines a distinct undifferentiated progenitor in the tendon/ligament and suppresses ectopic ossification
Naohiro Tachibana, Ryota Chijimatsu, Hiroyuki Okada, Takeshi Oichi, Yuki Taniguchi, Yuji Maenohara, Junya Miyahara, Hisatoshi Ishikura, Yasuhide Iwanaga, Yusuke Arino, Kosei Nagata, Hideki Nakamoto, So Kato, Toru Doi, Yoshitaka Matsubayashi, Yasushi Oshima, Asuka Terashima, Yasunori Omata, Fumiko Yano, Shingo Maeda, Shiro Ikegawa, Masahide Seki, Yutaka Suzuki, Sakae Tanaka, Taku Saito
Sci Adv. 2022 Aug; 8(33): eabn2138. Published online 2022 Aug 19. doi: 10.1126/sciadv.abn2138
PMCID:
PMC9390986
AbstractArticlePDF–14M
9.
Identification of a regulatory pathway inhibiting adipogenesis via RSPO2
Hua Dong, Wenfei Sun, Yang Shen, Miroslav Baláz, Lucia Balázová, Lianggong Ding, Mona Löffler, Bradford Hamilton, Nora Klöting, Matthias Blüher, Heike Neubauer, Holger Klein, Christian Wolfrum
Nat Metab. 2022; 4(1): 90–105. Published online 2022 Jan 13. doi: 10.1038/s42255-021-00509-1
PMCID:
PMC8803606
AbstractArticlePDF–24M
10.
Role of R-spondin 2 in arterial lymphangiogenesis and atherosclerosis
Bhupesh Singla, Hui-Ping Lin, Alex Chen, WonMo Ahn, Pushpankur Ghoshal, Mary Cherian-Shaw, Joseph White, Brian K Stansfield, Gábor Csányi
Cardiovasc Res. 2021 Jun 1; 117(6): 1489–1509. Published online 2020 Aug 4. doi: 10.1093/cvr/cvaa244
PMCID:
PMC8152716
AbstractArticlePDF–2.2M
11.
R-spondin substitutes for neuronal input for taste cell regeneration in adult mice
Xiaoli Lin, Chanyi Lu, Makoto Ohmoto, Katarzyna Choma, Robert F. Margolskee, Ichiro Matsumoto, Peihua Jiang
Proc Natl Acad Sci U S A. 2021 Jan 12; 118(2): e2001833118. Published online 2020 Dec 28. doi: 10.1073/pnas.2001833118
PMCID:
PMC7812810
AbstractArticlePDF–1.6M
12.
R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability
S. R. Jackson, M. F. D. M. Costa, C. F. Pastore, G. Zhao, A. I. Weiner, S. Adams, G. Palashikar, K. Quansah, K. Hankenson, D. R. Herbert, A. E. Vaughan
BMC Res Notes. 2020; 13: 54. Published online 2020 Feb 4. doi: 10.1186/s13104-020-4930-8
PMCID:
PMC7001225
AbstractArticlePDF–1.0M
13.
R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine
Teng Han, Emma M. Schatoff, Charles Murphy, Maria Paz Zafra, John E. Wilkinson, Olivier Elemento, Lukas E. Dow
Nat Commun. 2017; 8: 15945. Published online 2017 Jul 11. doi: 10.1038/ncomms15945
PMCID:
PMC5508203
AbstractArticlePDF–3.7M
14.
R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5
Hiroaki Nakashima, Bisei Ohkawara, Shinsuke Ishigaki, Takayasu Fukudome, Kenyu Ito, Mikito Tsushima, Hiroyuki Konishi, Tatsuya Okuno, Toshiro Yoshimura, Mikako Ito, Akio Masuda, Gen Sobue, Hiroshi Kiyama, Naoki Ishiguro, Kinji Ohno
Sci Rep. 2016; 6: 28512. Published online 2016 Jun 22. doi: 10.1038/srep28512
PMCID:
PMC4916433
AbstractArticlePDF–2.2M
15.
Oocyte-derived R-spondin2 promotes ovarian follicle development
Yuan Cheng, Kazuhiro Kawamura, Seido Takae, Masashi Deguchi, Qing Yang, Calvin Kuo, Aaron J. W. Hsueh
FASEB J. 2013 Jun; 27(6): 2175–2184. doi: 10.1096/fj.12-223412
PMCID:
PMC3659360
AbstractArticle
16.
Recombinant R-spondin2 and Wnt3a Up- and Down-Regulate Novel Target Genes in C57MG Mouse Mammary Epithelial Cells
Bolormaa Baljinnyam, Malgorzata Klauzinska, Saad Saffo, Robert Callahan, Jeffrey S. Rubin
PLoS One. 2012; 7(1): e29455. Published online 2012 Jan 4. doi: 10.1371/journal.pone.0029455
PMCID:
PMC3251591
AbstractArticlePDF–976K
17.
A New Common Integration Site, Int7, for the Mouse Mammary Tumor Virus in Mouse Mammary Tumors Identifies a Gene Whose Product Has Furin-Like and Thrombospondin-Like Sequences
William Lowther, Korah Wiley, Gilbert H. Smith, Robert Callahan
J Virol. 2005 Aug; 79(15): 10093–10096. doi: 10.1128/JVI.79.15.10093-10096.2005
PMCID:
PMC1181551
AbstractArticlePDF–145K
18.
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth
Marie-Cécile De Cian, Elodie P. Gregoire, Morgane Le Rolle, Simon Lachambre, Magali Mondin, Sheila Bell, Céline J. Guigon, Anne-Amandine Chassot, Marie-Christine Chaboissier
Cell Death Differ. 2020 Oct; 27(10): 2856–2871. Published online 2020 Apr 27. doi: 10.1038/s41418-020-0547-7
PMCID:
PMC7493947
AbstractArticlePDF–20M
19.
Crystal structure of R-spondin 2 in complex with the ectodomains of its receptors LGR5 and ZNRF3
Matthias Zebisch, E. Yvonne Jones
J Struct Biol. 2015 Aug; 191(2): 149–155. doi: 10.1016/j.jsb.2015.05.008
PMCID:
PMC4533229
AbstractArticlePDF–2.4M
20.
Unified rhombic lip origins of Group 3 and Group 4 medulloblastoma
Kyle S. Smith, Laure Bihannic, Brian L. Gudenas, Parthiv Haldipur, Ran Tao, Qingsong Gao, Yiran Li, Kimberly A. Aldinger, Igor Y. Iskusnykh, Victor V. Chizhikov, Matthew Scoggins, Silu Zhang, Angela Edwards, Mei Deng, Ian A. Glass, Lynne M. Overman, Jake Millman, Alexandria H. Sjoboen, Jennifer Hadley, Joseph Golser, Kshitij Mankad, Heather Tillman, Arzu Onar-Thomas, Amar Gajjar, Giles W. Robinson, Volker Hovestadt, Brent A. Orr, Zoltán Patay, Kathleen J. Millen, Paul A. Northcott
Nature. Author manuscript; available in PMC 2023 Mar 21.
Published in final edited form as: Nature. 2022 Sep; 609(7929): 1012–1020. Published online 2022 Sep 21. doi: 10.1038/s41586-022-05208-9
PMCID:
PMC9748853
AbstractArticlePDF–6.3M

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