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Items: 1 to 20 of 28

1.
A comprehensive analysis of the role of QPRT in breast cancer
Yiqing Yan, Lun Li, Zixin Wang, Jian Pang, Xinyu Guan, Yunchang Yuan, Zhenkun Xia, Wenjun Yi
Sci Rep. 2023; 13: 15414. Published online 2023 Sep 18. doi: 10.1038/s41598-023-42566-4
PMCID:
PMC10507026
AbstractArticlePDF–3.9M
2.
Targeting NAD+ biosynthesis overcomes panobinostat and bortezomib-induced malignant glioma resistance
Esther P. Jane, Daniel R. Premkumar, Swetha Thambireddy, Brian Golbourn, Sameer Agnihotri, Kelsey C. Bertrand, Stephen C. Mack, Max I. Myers, Ansuman Chattopadhyay, D. Lansing Taylor, Mark E. Schurdak, Andrew M. Stern, Ian F. Pollack
Mol Cancer Res. Author manuscript; available in PMC 2020 Jul 5.
Published in final edited form as: Mol Cancer Res. 2020 Jul; 18(7): 1004–1017. Published online 2020 Apr 1. doi: 10.1158/1541-7786.MCR-19-0669
PMCID:
PMC7335346
AbstractArticlePDF–2.5M
3.
Loss of the Chr16p11.2 ASD candidate gene QPRT leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model
Denise Haslinger, Regina Waltes, Afsheen Yousaf, Silvia Lindlar, Ines Schneider, Chai K. Lim, Meng-Miao Tsai, Boyan K. Garvalov, Amparo Acker-Palmer, Nicolas Krezdorn, Björn Rotter, Till Acker, Gilles J. Guillemin, Simone Fulda, Christine M. Freitag, Andreas G. Chiocchetti
Mol Autism. 2018; 9: 56. Published online 2018 Nov 6. doi: 10.1186/s13229-018-0239-z
PMCID:
PMC6220561
AbstractArticlePDF–1.9M
4.
Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease
Simon P. Jones, Nunzio F. Franco, Bianca Varney, Gayathri Sundaram, David A. Brown, Josien de Bie, Chai K. Lim, Gilles J. Guillemin, Bruce J. Brew
PLoS One. 2015; 10(6): e0131389. Published online 2015 Jun 26. doi: 10.1371/journal.pone.0131389
PMCID:
PMC4482723
AbstractArticlePDF–1.3M
5.
Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans
Edwin B. Yan, Tony Frugier, Chai K. Lim, Benjamin Heng, Gayathri Sundaram, May Tan, Jeffrey V. Rosenfeld, David W. Walker, Gilles J. Guillemin, Maria Cristina Morganti-Kossmann
J Neuroinflammation. 2015; 12: 110. Published online 2015 May 30. doi: 10.1186/s12974-015-0328-2
PMCID:
PMC4457980
AbstractArticlePDF–1.3M
6.
QPRT: a potential marker for follicular thyroid carcinoma including minimal invasive variant; a gene expression, RNA and immunohistochemical study
Nora Hinsch, Matthias Frank, Claudia Döring, Christian Vorländer, Martin-Leo Hansmann
BMC Cancer. 2009; 9: 93. Published online 2009 Mar 26. doi: 10.1186/1471-2407-9-93
PMCID:
PMC2667537
AbstractArticlePDF–1.3M
7.
Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis
Hyung-Seop Youn, Tae Gyun Kim, Mun-Kyoung Kim, Gil Bu Kang, Jung Youn Kang, Jung-Gyu Lee, Jun Yop An, Kyoung Ryoung Park, Youngjin Lee, Young Jun Im, Jun Hyuck Lee, Soo Hyun Eom
Sci Rep. 2016; 6: 19681. Published online 2016 Jan 25. doi: 10.1038/srep19681
PMCID:
PMC4726147
AbstractArticlePDF–2.2M
8.
STRUCTURAL AND KINETIC CHARACTERIZATION OF QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (hQPRTase) FROM HOMO SAPIENS
Huanting Liu, Kerry Woznica, Gemma Catton, Amanda Crawford, Nigel Botting, James H. Naismith
J Mol Biol. Author manuscript; available in PMC 2012 Apr 16.
Published in final edited form as: J Mol Biol. 2007 Oct 26; 373(3): 755–763. Published online 2007 Aug 24. doi: 10.1016/j.jmb.2007.08.043
PMCID:
PMC3326535
AbstractArticlePDF–3.1M
9.
Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT
Zhang Yue, Jia Shusheng, Song Hongtao, Zhao Shu, Huang Lan, Zhang Qingyuan, Cheng Shaoqiang, Huang Yuanxi
Aging (Albany NY) 2020 Jul 31; 12(14): 14754–14774. Published online 2020 Jul 27. doi: 10.18632/aging.103538
Correction in:
Aging (Albany NY). 2022 Jan 15; 14(1): 528–529.
PMCID:
PMC7425442
AbstractArticlePDF–3.9M
10.
Quinolinate Phosphoribosyltransferase is an Antiviral Host Factor Against Hepatitis C Virus Infection
Zhilong Wang, Yanhang Gao, Chao Zhang, Haiming Hu, Dongwei Guo, Yi Xu, Qiuping Xu, Weihong Zhang, Sisi Deng, Pingyun Lv, Yan Yang, Yanhua Ding, Qingquan Li, Changjiang Weng, Xinwen Chen, Sitang Gong, Hairong Chen, Junqi Niu, Hong Tang
Sci Rep. 2017; 7: 5876. Published online 2017 Jul 19. doi: 10.1038/s41598-017-06254-4
PMCID:
PMC5517448
AbstractArticlePDF–3.9M
11.
Enzymology of NAD+ homeostasis in man
G. Magni, A. Amici, M. Emanuelli, G. Orsomando, N. Raffaelli, S. Ruggieri
Cell Mol Life Sci. 2004 Jan; 61(1): 19–34. doi: 10.1007/s00018-003-3161-1
PMCID:
PMC11138864
AbstractArticlePDF–291K
12.
FBXO22 degrades nuclear PTEN to promote tumorigenesis
Meng-Kai Ge, Na Zhang, Li Xia, Cheng Zhang, Shuang-Shu Dong, Zhan-Ming Li, Yan Ji, Min-Hua Zheng, Jing Sun, Guo-Qiang Chen, Shao-Ming Shen
Nat Commun. 2020; 11: 1720. Published online 2020 Apr 6. doi: 10.1038/s41467-020-15578-1
PMCID:
PMC7136256
AbstractArticlePDF–3.8M
13.
GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer
Eun Myoung Shin, Vinh Thang Huynh, Sultan Abda Neja, Chia Yi Liu, Anandhkumar Raju, Kelly Tan, Nguan Soon Tan, Jayantha Gunaratne, Xuezhi Bi, Lakshminarayan M. Iyer, L. Aravind, Vinay Tergaonkar
Sci Adv. 2021 Mar; 7(12): eabe2470. Published online 2021 Mar 17. doi: 10.1126/sciadv.abe2470
PMCID:
PMC7968844
AbstractArticlePDF–1.1M
14.
Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism
Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva
Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650
Correction in:
Nat Commun. 2023; 14: 569.
PMCID:
PMC3996537
AbstractArticlePDF–1.9M
15.
Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase
Daniel C. Scott, Jared T. Hammill, Jaeki Min, David Y. Rhee, Michele Connelly, Vladislav O. Sviderskiy, Deepak Bhasin, Yizhe Chen, Su-Sien Ong, Sergio C. Chai, Asli N. Goktug, Guochang Huang, Julie K. Monda, Jonathan Low, Ho Shin Kim, Joao A. Paulo, Joe R. Cannon, Anang A. Shelat, Taosheng Chen, Ian R. Kelsall, Arno F. Alpi, Vishwajeeth Pagala, Xusheng Wang, Junmin Peng, Bhuvanesh Singh, J. Wade Harper, Brenda A. Schulman, R. Kip Guy
Nat Chem Biol. Author manuscript; available in PMC 2017 Dec 5.
Published in final edited form as: Nat Chem Biol. 2017 Aug; 13(8): 850–857. Published online 2017 Jun 5. doi: 10.1038/nchembio.2386
PMCID:
PMC5577376
AbstractArticlePDF–1.2M
16.
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057
PMCID:
PMC6831851
AbstractArticlePDF–9.8M
17.
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele
PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975
PMCID:
PMC7758050
AbstractArticlePDF–4.2M
18.
Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions
Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano
Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604
PMCID:
PMC515316
AbstractArticlePDF–181K
19.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake
Proteomics. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561
PMCID:
PMC3773505
AbstractArticlePDF–630K
20.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M

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