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Select item 110769881.

High FLT3 expression increases immune‐cell infiltration in the tumor microenvironment and correlates with prolonged disease‐free survival in patients with non‐small cell lung cancer

Łukasz Kuncman, Magdalena Orzechowska, Tomasz Milecki, Jakub Kucharz, Jacek Fijuth

Mol Oncol. 2024 May; 18(5): 1316–1326. Published online 2024 Feb 7. doi: 10.1002/1878-0261.13597

PMCID:: PMC11076988

Abstract Article PDF–2.7M

Select item 109693212.

Prevalence of FMS-like tyrosine kinase 3/internal tandem duplication (FLT3/ITD+) in de novo acute myeloid leukemia patients categorized according to cytogenetic risk

Everson Augusto Krum, Mihoko Yamamoto, Maria de Lourdes Lopes Ferrari Chauffaille

Sao Paulo Med J. 2009; 127(1): 23–27. Published online 2009 May 11. doi: 10.1590/S1516-31802009000100006

PMCID:: PMC10969321

Abstract Article PDF–149K

Select item 108035563.

Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia

Angela Gutierrez-Camino, Chantal Richer, Manon Ouimet, Claire Fuchs, Sylvie Langlois, Fida Khater, Maxime Caron, Patrick Beaulieu, Pascal St-Onge, Alain R. Bataille, Daniel Sinnett

Br J Cancer. 2024 Feb 10; 130(2): 317–326. Published online 2023 Dec 4. doi: 10.1038/s41416-023-02511-8

PMCID:: PMC10803556

Abstract Article PDF–1.1M

Select item 105978404.

A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo

Eirini Giannakopoulou, Madeleine Lehander, Stina Virding Culleton, Weiwen Yang, Yingqian Li, Terhi Karpanen, Tetsuichi Yoshizato, Even H. Rustad, Morten Milek Nielsen, Ravi Chand Bollineni, Trung T. Tran, Marina Delic-Sarac, Thea Johanne Gjerdingen, Karolos Douvlataniotis, Maarja Laos, Muhammad Ali, Amy Hillen, Stefania Mazzi, Desmond Wai Loon Chin, Adi Mehta, Jeppe Sejerø Holm, Amalie Kai Bentzen, Marie Bill, Marieke Griffioen, Tobias Gedde-Dahl, Sören Lehmann, Sten Eirik W. Jacobsen, Petter S. Woll, Johanna Olweus

Nat Cancer. 2023; 4(10): 1474–1490. Published online 2023 Oct 2. doi: 10.1038/s43018-023-00642-8

PMCID:: PMC10597840

Abstract Article PDF–20M

Select item 105586185.

Targeting conditioned media dependencies and FLT-3 in chronic lymphocytic leukemia

Salma Parvin, Aditi Aryal, Shanye Yin, Geoffrey G. Fell, Matthew S. Davids, Catherine J. Wu, Anthony Letai

Blood Adv. 2023 Oct 10; 7(19): 5877–5889. Published online 2023 Jul 20. doi: 10.1182/bloodadvances.2022008207

PMCID:: PMC10558618

Abstract Article PDF–1.2M

Select item 105290566.

Insight and Recommendations for Fragile X-Premutation-Associated Conditions from the Fifth International Conference on FMR1 Premutation

Flora Tassone, Dragana Protic, Emily Graves Allen, Alison D. Archibald, Anna Baud, Ted W. Brown, Dejan B. Budimirovic, Jonathan Cohen, Brett Dufour, Rachel Eiges, Nicola Elvassore, Lidia V. Gabis, Samantha J. Grudzien, Deborah A. Hall, David Hessl, Abigail Hogan, Jessica Ezzell Hunter, Peng Jin, Poonnada Jiraanont, Jessica Klusek, R. Frank Kooy, Claudine M. Kraan, Cecilia Laterza, Andrea Lee, Karen Lipworth, Molly Losh, Danuta Loesch, Reymundo Lozano, Marsha R. Mailick, Apostolos Manolopoulos, Veronica Martinez-Cerdeno, Yingratana McLennan, Robert M. Miller, Federica Alice Maria Montanaro, Matthew W. Mosconi, Sarah Nelson Potter, Melissa Raspa, Susan M. Rivera, Katharine Shelly, Peter K. Todd, Katarzyna Tutak, Jun Yi Wang, Anne Wheeler, Tri Indah Winarni, Marwa Zafarullah, Randi J. Hagerman

Cells. 2023 Sep; 12(18): 2330. Published online 2023 Sep 21. doi: 10.3390/cells12182330

PMCID:: PMC10529056

Abstract Article PDF–4.4M

Select item 102304047.

Disrupting autophagy in FLT3-mutant acute myeloid leukemia

Steven Grant

Haematologica. 2023 Jun 1; 108(6): 1458–1460. Published online 2022 Nov 17. doi: 10.3324/haematol.2022.282054

PMCID:: PMC10230404

Article PDF–1.2M

Select item 99105698.

FLT3 functional low-frequency variant rs76428106-C is associated with susceptibility to systemic sclerosis

Javier Martínez-López, Martin Kerick, Lourdes Ortiz-Fernández, Marialbert Acosta-Herrera, Ana Márquez, Javier Martín

Rheumatology (Oxford) 2023 Feb; 62(SI): SI138–SI142. Published online 2022 Jul 25. doi: 10.1093/rheumatology/keac406

PMCID:: PMC9910569

Abstract Article PDF–240K

Select item 97912929.

Association between FLT3-ITD and additional chromosomal abnormalities in the prognosis of acute promyelocytic leukemia

Minh Phuong Vu, Cuc Nhung Nguyen, Hoang Vu, Tuyet Mai Nguyen, Tuan Tung Nguyen, Phuong Thao Pham

J Int Med Res. 2022 Dec; 50(12): 03000605221138490. Published online 2022 Dec 20. doi: 10.1177/03000605221138490

PMCID:: PMC9791292

Abstract Article PDF–454K

Select item 975343310.

Clinical and molecular features of FLT3 juxtamembrane domain missense mutations in acute myeloid leukaemia

Christopher E. Jensen, Nathan D. Montgomery, Jonathan Galeotti, Matthew C. Foster, Joshua F. Zeidner

J Cell Mol Med. 2022 Dec; 26(24): 6079–6082. Published online 2022 Nov 28. doi: 10.1111/jcmm.17608

PMCID:: PMC9753433

Article PDF–236K

Select item 970704411.

FLT3 Gene Mutations in Acute Myeloid Leukemia Patients in Northeast Thailand

Nang Ei Ei Aung, Supawadee Yamsri, Nattiya Teawtrakul, Piyawan Kamsaen, Supan Fucharoen

Med Sci Monit Basic Res. 2022; 28: e937446-1–e937446-11. Published online 2022 Nov 24. doi: 10.12659/MSMBR.937446

PMCID:: PMC9707044

Abstract Article PDF–1.2M

Select item 965263712.

Lack of FLT3-ITD in Tunisian childhood acute lymphoblastic leukemia

Rim Frikha, Nawel Abdellaoui, Olfa Kassar, Tarek Rebai

Afr Health Sci. 2022 Jun; 22(2): 318–322. doi: 10.4314/ahs.v22i2.35

PMCID:: PMC9652637

Abstract Article PDF–286K

Select item 952122113.

Association of FLT3-internal tandem duplication length with overall survival in acute myeloid leukemia: a systematic review and meta-analysis

Tobias B. Polak, Joost van Rosmalen, Stijn Dirven, Julia K. Herzig, Jacqueline Cloos, Soheil Meshinchi, Konstanze Döhner, Jeroen J.W.M. Janssen, David G.J. Cucchi

Haematologica. 2022 Oct 1; 107(10): 2506–2510. Published online 2022 Jul 7. doi: 10.3324/haematol.2022.281218

PMCID:: PMC9521221

Article PDF–2.4M

Select item 929225614.

Post‐transplant maintenance therapy in patients with FLT3‐mutated acute myeloid leukemia: Real‐world treatment patterns and outcomes

James D. Griffin, Yan Song, Hongbo Yang, Jonathan Freimark, Manasee V. Shah

Eur J Haematol. 2021 Nov; 107(5): 553–565. Published online 2021 Aug 11. doi: 10.1111/ejh.13692

PMCID:: PMC9292256

Abstract Article PDF–1000K

Select item 896890015.

Characteristics and outcome of patients with core-binding factor acute myeloid leukemia and FLT3-ITD: results from an international collaborative study

Sabine Kayser, Michael Kramer, David Martínez-Cuadrón, Justin Grenet, Klaus H. Metzeler, Zuzana Sustkova, Marlise R. Luskin, Andrew M. Brunner, Michelle A. Elliott, Cristina Gil, Sandra Casal Marini, Zdeněk Ráčil, Petr Cetkovsky, Jan Novak, Alexander E. Perl, Uwe Platzbecker, Friedrich Stölzel, Anthony D. Ho, Christian Thiede, Richard M. Stone, Christoph Röllig, Pau Montesinos, Richard F. Schlenk, Mark J. Levis

Haematologica. 2022 Apr 1; 107(4): 836–843. Published online 2021 Aug 5. doi: 10.3324/haematol.2021.278645

PMCID:: PMC8968900

Abstract Article PDF–1.5M

Select item 896788216.

Transcriptome-wide association study reveals increased neuronal FLT3 expression is associated with Tourette’s syndrome

Calwing Liao, Veikko Vuokila, Hélène Catoire, Fulya Akçimen, Jay P. Ross, Cynthia V. Bourassa, Patrick A. Dion, Inge A. Meijer, Guy A. Rouleau

Commun Biol. 2022; 5: 289. Published online 2022 Mar 30. doi: 10.1038/s42003-022-03231-0

PMCID:: PMC8967882

Abstract Article PDF–682K

Select item 896191317.

Whole exome sequencing of pediatric leukemia reveals a novel InDel within FLT-3 gene in AML patient from Mizo tribal population, Northeast India

Andrew Vanlallawma, Doris Lallawmzuali, Jeremy L. Pautu, Vinod Scaria, Sridhar Sivasubbu, Nachimuthu Senthil Kumar

BMC Genom Data. 2022; 23: 23. Published online 2022 Mar 28. doi: 10.1186/s12863-022-01037-x

PMCID:: PMC8961913

Abstract Article PDF–1.1M

Select item 872728618.

Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results

Frank G. Rücker, Ling Du, Tamara J. Luck, Axel Benner, Julia Krzykalla, Insa Gathmann, Maria Teresa Voso, Sergio Amadori, Thomas W. Prior, Joseph M. Brandwein, Frederick R. Appelbaum, Bruno C. Medeiros, Martin S. Tallman, Lynn Savoie, Jorge Sierra, Celine Pallaud, Miguel A. Sanz, Joop H. Jansen, Dietger Niederwieser, Thomas Fischer, Gerhard Ehninger, Michael Heuser, Arnold Ganser, Lars Bullinger, Richard A. Larson, Clara D. Bloomfield, Richard M. Stone, Hartmut Döhner, Christian Thiede, Konstanze Döhner

Leukemia. 2022; 36(1): 90–99. Published online 2021 Jul 28. doi: 10.1038/s41375-021-01323-0

PMCID:: PMC8727286

Abstract Article PDF–1.1M

Select item 862251019.

Molecular Modeling Studies of N-phenylpyrimidine-4-amine Derivatives for Inhibiting FMS-like Tyrosine Kinase-3

Suparna Ghosh, Seketoulie Keretsu, Seung Joo Cho

Int J Mol Sci. 2021 Nov; 22(22): 12511. Published online 2021 Nov 19. doi: 10.3390/ijms222212511

PMCID:: PMC8622510

Abstract Article PDF–15M

Select item 861635220.

Modulation of FLT3-ITD Localization and Targeting of Distinct Downstream Signaling Pathways as Potential Strategies to Overcome FLT3-Inhibitor Resistance

Maximilian Fleischmann, Mike Fischer, Ulf Schnetzke, Colin Fortner, Joanna Kirkpatrick, Florian H. Heidel, Andreas Hochhaus, Sebastian Scholl

Cells. 2021 Nov; 10(11): 2992. Published online 2021 Nov 3. doi: 10.3390/cells10112992

PMCID:: PMC8616352

Abstract Article PDF–5.8M

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