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Select item 87556631.

The role of GTPase-activating protein ARHGAP26 in human cancers

Lingye Zhang, Anni Zhou, Shengtao Zhu, Li Min, Si Liu, Peng Li, Shutian Zhang

Mol Cell Biochem. 2022; 477(1): 319–326. Published online 2021 Oct 30. doi: 10.1007/s11010-021-04274-3

PMCID:: PMC8755663

Abstract Article PDF–1.9M

Select item 64571772.

Circular RNA ARHGAP26 is over-expressed and its downregulation inhibits cell proliferation and promotes cell apoptosis in gastric cancer cells

LV Wangxia, Yang Fang, Yongjun Liu, Yazhen Zhao, Zhong Shi, Haijun Zhong

Saudi J Gastroenterol. 2019 Mar-Apr; 25(2): 119–125. doi: 10.4103/sjg.SJG_283_18

PMCID:: PMC6457177

Abstract Article PDF–2.6M

Select item 55699703.

Involvement of Rho GAP GRAF1 in maintenance of epithelial phenotype

Miriam Regev, Helena Sabanay, Elena Kartvelishvily, Zvi Kam, Alexander D. Bershadsky

Cell Adh Migr. 2017; 11(4): 367–383. Published online 2016 Sep 2. doi: 10.1080/19336918.2016.1227910

PMCID:: PMC5569970

Abstract Article PDF–1.8M

Select item 32166634.

The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading

Gary J. Doherty, Monika K. Åhlund, Mark T. Howes, Björn Morén, Robert G. Parton, Harvey T. McMahon, Richard Lundmark

Mol Biol Cell. 2011 Nov 15; 22(22): 4380–4389. doi: 10.1091/mbc.E10-12-0936

PMCID:: PMC3216663

Abstract Article PDF–3.7M

Select item 29275065.

GTPase regulator associated with the focal adhesion kinase (GRAF) transcript was down-regulated in patients with myeloid malignancies

Zhen Qian, Jun Qian, Jiang Lin, Dong-ming Yao, Qin Chen, Run-bi Ji, Yun Li, Gao-fei Xiao, Jian-yong Li

J Exp Clin Cancer Res. 2010; 29(1): 111. Published online 2010 Aug 12. doi: 10.1186/1756-9966-29-111

PMCID:: PMC2927506

Abstract Article PDF–283K

Select item 29159496.

Decreased expression of GRAF1/OPHN-1-L in the X-linked alpha thalassemia mental retardation syndrome

Vincenza Barresi, Angela Ragusa, Marco Fichera, Nicolò Musso, Lucia Castiglia, Giancarlo Rappazzo, Salvatore Travali, Teresa Mattina, Corrado Romano, Guido Cocchi, Daniele F Condorelli

BMC Med Genomics. 2010; 3: 28. Published online 2010 Jul 6. doi: 10.1186/1755-8794-3-28

PMCID:: PMC2915949

Abstract Article PDF–620K

Select item 23611287.

Characterisation of the GRAF gene promoter and its methylation in patients with acute myeloid leukaemia and myelodysplastic syndrome

S E Bojesen, O Ammerpohl, A Weinhäusl, O A Haas, H Mettal, R M Bohle, A Borkhardt, U Fuchs

Br J Cancer. 2006 Jan 30; 94(2): 323–332. Published online 2006 Jan 10. doi: 10.1038/sj.bjc.6602939

PMCID:: PMC2361128

Abstract Article PDF–238K

Select item 96017978.

Missense Variants in GFRA1 and NPNT Are Associated with Congenital Anomalies of the Kidney and Urinary Tract

Mohamed H. Al-Hamed, John A. Sayer, Nada Alsahan, Noel Edwards, Wafaa Ali, Maha Tulbah, Faiqa Imtiaz

Genes (Basel) 2022 Oct; 13(10): 1687. Published online 2022 Sep 21. doi: 10.3390/genes13101687

PMCID:: PMC9601797

Abstract Article PDF–1.0M

Select item 64748629.

SMURF1-mediated ubiquitination of ARHGAP26 promotes ovarian cancer cell invasion and migration

Xuri Chen, Shaoyun Chen, Yao Li, Yanling Gao, Shuying Huang, Hongping Li, Yuanfang Zhu

Exp Mol Med. 2019 Apr; 51(4): 46. Published online 2019 Apr 19. doi: 10.1038/s12276-019-0236-0

PMCID:: PMC6474862

Abstract Article PDF–2.7M

Select item 471278310.

Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1

Monika K. Francis, Mikkel R. Holst, Maite Vidal-Quadras, Sara Henriksson, Rachel Santarella-Mellwig, Linda Sandblad, Richard Lundmark

J Cell Sci. 2015 Nov 15; 128(22): 4183–4195. doi: 10.1242/jcs.174417

PMCID:: PMC4712783

Abstract Article

Select item 313830411.

Skeletal Muscle Differentiation and Fusion Are Regulated by the BAR-containing Rho-GTPase-activating Protein (Rho-GAP), GRAF1

Jason T. Doherty, Kaitlin C. Lenhart, Morgan V. Cameron, Christopher P. Mack, Frank L. Conlon, Joan M. Taylor

J Biol Chem. 2011 Jul 22; 286(29): 25903–25921. Published online 2011 May 26. doi: 10.1074/jbc.M111.243030

PMCID:: PMC3138304

Abstract Article PDF–7.8M

Select item 265644212.

Dissecting the thermodynamics of GAP-RhoA interactions

Filip Jelen, Pawel Lachowicz, Wlodzimierz Apostoluk, Agnieszka Mateja, Zygmunt S. Derewenda, Jacek Otlewski

J Struct Biol. Author manuscript; available in PMC 2010 Jan 1.

Published in final edited form as: J Struct Biol. 2009 Jan; 165(1): 10–18. Published online 2008 Oct 2. doi: 10.1016/j.jsb.2008.09.007

PMCID:: PMC2656442

Abstract Article PDF–2.6M

Select item 1684013.

The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q

Arndt Borkhardt, Stig Bojesen, Oskar A. Haas, Uta Fuchs, Dominique Bartelheimer, Ivan F. Loncarevic, Rainer M. Bohle, Jochen Harbott, Reinald Repp, Ulrich Jaeger, Susanne Viehmann, Traudl Henn, Petra Korth, Dirk Scharr, Fritz Lampert

Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9168–9173. Published online 2000 Jul 25. doi: 10.1073/pnas.150079597

PMCID:: PMC16840

Abstract Article PDF–501K

Select item 630096814.

RhoA/ROCK/ARHGAP26 signaling in the eutopic and ectopic endometrium is involved in clinical characteristics of adenomyosis

Caixia Jiang, Wei Gong, Rong Chen, Huihui Ke, Xiaoyan Qu, Weihong Yang, Zhongping Cheng

J Int Med Res. 2018 Dec; 46(12): 5019–5029. Published online 2018 Nov 2. doi: 10.1177/0300060518789038

PMCID:: PMC6300968

Abstract Article PDF–336K

Select item 1071365815.

GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis

Qiang Zhu, Matthew E. Combs, Juan Liu, Xue Bai, Wenbo B. Wang, Laura E. Herring, Jiandong Liu, Jason W. Locasale, Dawn E. Bowles, Ryan T. Gross, Michelle Mendiola Pla, Christopher P. Mack, Joan M. Taylor

Nat Commun. 2023; 14: 8187. Published online 2023 Dec 11. doi: 10.1038/s41467-023-43889-6

PMCID:: PMC10713658

Abstract Article PDF–9.0M

Select item 385172016.

ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding

Qiong Wang, Haipeng Hui, Zhendong Guo, Weina Zhang, Yaou Hu, Tao He, Yanhong Tai, Peng Peng, Li Wang

RNA. 2013 Nov; 19(11): 1525–1536. doi: 10.1261/rna.041533.113

PMCID:: PMC3851720

Abstract Article PDF–1.0M

Select item 277958317.

A common non-synonymous variant in GLUT9 is a determinant of serum uric acid levels in Old Order Amish

Patrick F. McArdle, Afshin Parsa, Yen-Pei C. Chang, Matthew R. Weir, Jeffery R. O'Connell, Braxton D. Mitchell, Alan R. Shuldiner

Arthritis Rheum. Author manuscript; available in PMC 2009 Nov 20.

Published in final edited form as: Arthritis Rheum. 2008 Sep; 58(9): 2874–2881. doi: 10.1002/art.23752

PMCID:: PMC2779583

Abstract Article PDF–693K

Select item 23131018.

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase.

J D Hildebrand, J M Taylor, J T Parsons

Mol Cell Biol. 1996 Jun; 16(6): 3169–3178. doi: 10.1128/mcb.16.6.3169

PMCID:: PMC231310

Summary PDF–1.0M

Select item 719985519.

GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508

Safa Lucken-Ardjomande Häsler, Yvonne Vallis, Mathias Pasche, Harvey T. McMahon

J Cell Biol. 2020 May 4; 219(5): e201811014. Published online 2020 Apr 28. doi: 10.1083/jcb.201811014

PMCID:: PMC7199855

Abstract Article PDF–14M

Select item 324360720.

NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons

Kazumasa Yokoyama, Tohru Tezuka, Masaharu Kotani, Takanobu Nakazawa, Naosuke Hoshina, Yasushi Shimoda, Shigeru Kakuta, Katsuko Sudo, Kazutada Watanabe, Yoichiro Iwakura, Tadashi Yamamoto

EMBO J. 2011 Nov 30; 30(23): 4739–4754. Published online 2011 Sep 23. doi: 10.1038/emboj.2011.348

PMCID:: PMC3243607

Abstract Article PDF–2.4M

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PMC Links for Gene (Select 23092) (42)
PMC
Homo sapiens keratinocyte associated protein 2, mRNA (cDNA clone MGC:35430 IMAGE...
Homo sapiens keratinocyte associated protein 2, mRNA (cDNA clone MGC:35430 IMAGE:5189880), complete cds
gi|20987524|gb|BC029806.1|

Nucleotide
Sequence 1 from Patent WO03064470
Sequence 1 from Patent WO03064470
gi|39103577|emb|AX814342.1||pat|WO| 470|1

Nucleotide
MULTISPECIES: restriction endonuclease subunit S [Mycobacterium]
MULTISPECIES: restriction endonuclease subunit S [Mycobacterium]
gi|489509204|ref|WP_003414068.1|

Protein
PREDICTED: Homo sapiens Rho GTPase activating protein 26 (ARHGAP26), transcript ...
PREDICTED: Homo sapiens Rho GTPase activating protein 26 (ARHGAP26), transcript variant X37, mRNA
gi|2217355227|ref|XM_047416993.1|

Nucleotide

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