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Select item 98900261.

KDM4C in germinal center lymphoma: a new piece of the epigenetic puzzle

Karina Close, Jude Fitzgibbon

Haematologica. 2023 Feb 1; 108(2): 297–298. Published online 2022 Apr 28. doi: 10.3324/haematol.2022.280898

PMCID:: PMC9890026

Article PDF–745K

Select item 98900212.

Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas

Cristina López, Nikolai Schleussner, Stephan H. Bernhart, Kortine Kleinheinz, Stephanie Sungalee, Henrike L. Sczakiel, Helene Kretzmer, Umut H. Toprak, Selina Glaser, Rabea Wagener, Ole Ammerpohl, Susanne Bens, Maciej Giefing, Juan C. González Sánchez, Gordana Apic, Daniel Hübschmann, Martin Janz, Markus Kreuz, Anja Mottok, Judith M. Müller, Julian Seufert, Steve Hoffmann, Jan O. Korbel, Robert B. Russell, Roland Schüle, Lorenz Trümper, Wolfram Klapper, Bernhard Radlwimmer, Peter Lichter, Ralf Küppers, Matthias Schlesner, Stephan Mathas, Reiner Siebert

Haematologica. 2023 Feb 1; 108(2): 543–554. Published online 2022 Apr 28. doi: 10.3324/haematol.2021.280005

PMCID:: PMC9890021

Abstract Article PDF–2.0M

Select item 92528593.

Novel germline variant in the histone demethylase and transcription regulator KDM4C induces a multi-cancer phenotype

Riku Katainen, Iikki Donner, Maritta Räisänen, Davide Berta, Anna Kuosmanen, Eevi Kaasinen, Marja Hietala, Lauri A Aaltonen

J Med Genet. 2022 Jul; 59(7): 644–651. Published online 2021 Jul 19. doi: 10.1136/jmedgenet-2021-107747

PMCID:: PMC9252859

Abstract Article PDF–1.6M

Select item 87705654.

JMJD2C-mediated long non-coding RNA MALAT1/microRNA-503-5p/SEPT2 axis worsens non-small cell lung cancer

Jun Zhang, Mingliang Wang, Jiashun Wang, Wendong Wang

Cell Death Dis. 2022 Jan; 13(1): 65. Published online 2022 Jan 19. doi: 10.1038/s41419-022-04513-5

PMCID:: PMC8770565

Abstract Article PDF–4.3M

Select item 77191935.

Rare genetic variants in the gene encoding histone lysine demethylase 4C (KDM4C) and their contributions to susceptibility to schizophrenia and autism spectrum disorder

Hidekazu Kato, Itaru Kushima, Daisuke Mori, Akira Yoshimi, Branko Aleksic, Yoshihiro Nawa, Miho Toyama, Sho Furuta, Yanjie Yu, Kanako Ishizuka, Hiroki Kimura, Yuko Arioka, Keita Tsujimura, Mako Morikawa, Takashi Okada, Toshiya Inada, Masahiro Nakatochi, Keiko Shinjo, Yutaka Kondo, Kozo Kaibuchi, Yasuko Funabiki, Ryo Kimura, Toshimitsu Suzuki, Kazuhiro Yamakawa, Masashi Ikeda, Nakao Iwata, Tsutomu Takahashi, Michio Suzuki, Yuko Okahisa, Manabu Takaki, Jun Egawa, Toshiyuki Someya, Norio Ozaki

Transl Psychiatry. 2020; 10: 421. Published online 2020 Dec 5. doi: 10.1038/s41398-020-01107-7

PMCID:: PMC7719193

Abstract Article PDF–1.6M

Select item 73604806.

Wnt-Induced Stabilization of KDM4C Is Required for Wnt/β-Catenin Target Gene Expression and Glioblastoma Tumorigenesis

Yaohui Chen, Runping Fang, Chen Yue, Guoqiang Chang, Peng Li, Qing Guo, Jing Wang, Aidong Zhou, Sicong Zhang, Gregory N Fuller, Xiaobing Shi, Suyun Huang

Cancer Res. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Cancer Res. 2020 Mar 1; 80(5): 1049–1063. Published online 2019 Dec 30. doi: 10.1158/0008-5472.CAN-19-1229

PMCID:: PMC7360480

Abstract Article PDF–2.1M

Select item 68196497.

JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway

Xinnan Wu, Ruixiao Li, Qing Song, Chengcheng Zhang, Ru Jia, Zhifen Han, Lihong Zhou, Hua Sui, Xuan Liu, Huirong Zhu, Liu Yang, Yan Wang, Qing Ji, Qi Li

J Exp Clin Cancer Res. 2019; 38: 435. Published online 2019 Oct 29. doi: 10.1186/s13046-019-1439-x

Correction in:: J Exp Clin Cancer Res. 2022; 41: 205.

PMCID:: PMC6819649

Abstract Article PDF–4.9M

Select item 58495688.

Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis

Lourdes Ortiz-Fernández, Francisco David Carmona, Raquel López-Mejías, Maria Francisca González-Escribano, Paul A Lyons, Ann W Morgan, Amr H Sawalha, Kenneth G C Smith, Miguel A González-Gay, Javier Martín, Spanish GCA Study Group, UK GCA Consortium, Turkish Takayasu Study Group, Vasculitis Clinical Research Consortium, IgAV Study Group, AAV Study group

Ann Rheum Dis. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Ann Rheum Dis. 2018 Apr; 77(4): 589–595. Published online 2018 Jan 27. doi: 10.1136/annrheumdis-2017-212372

Correction in:: Ann Rheum Dis. 2018 Jun; 77(6): 950.

PMCID:: PMC5849568

Abstract Article PDF–460K

Select item 50945789.

KDM4C Activity Modulates Cell Proliferation and Chromosome Segregation in Triple-Negative Breast Cancer

Jeison Garcia, Fernando Lizcano

Breast Cancer (Auckl) 2016; 10: 169–175. Published online 2016 Nov 2. doi: 10.4137/BCBCR.S40182

PMCID:: PMC5094578

Abstract Article PDF–2.3M

Select item 503534210.

KDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 Expression

Xiang Yuan, Jinyu Kong, Zhikun Ma, Na Li, Ruinuo Jia, Yiwen Liu, Fuyou Zhou, Qimin Zhan, Gang Liu, Shegan Gao

Neoplasia. 2016 Oct; 18(10): 594–609. Published online 2016 Sep 19. doi: 10.1016/j.neo.2016.08.005

Correction in:: Neoplasia. 2016 Dec; 18(12): 810.

PMCID:: PMC5035342

Abstract Article PDF–3.0M

Select item 481355611.

Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C)

Lindsey R. Pack, Keith R. Yamamoto, Danica Galonić Fujimori

J Biol Chem. 2016 Mar 18; 291(12): 6060–6070. Published online 2016 Jan 8. doi: 10.1074/jbc.M115.696864

PMCID:: PMC4813556

Abstract Article PDF–962K

Select item 416879412.

Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

Ulrike Leurs, Brian Lohse, Kasper D. Rand, Shonoi Ming, Erik S. Riise, Philip A. Cole, Jesper L. Kristensen, Rasmus P. Clausen

ACS Chem Biol. 2014 Sep 19; 9(9): 2131–2138. Published online 2014 Jul 11. doi: 10.1021/cb500374f

PMCID:: PMC4168794

Abstract Article PDF–1.4M

Select item 405830613.

Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors

Tae-Dong Kim, James R Fuchs, Eric Schwartz, Dalia Abdelhamid, Jonathan Etter, William L Berry, Chenglong Li, Michael A Ihnat, Pui-Kai Li, Ralf Janknecht

Am J Transl Res. 2014; 6(3): 236–247. Published online 2014 May 15.