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Items: 1 to 20 of 48

1.
Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells
Yura Lee, Jung-Il Jung, Kyeong-Yong Park, Soon Ae Kim, Jiyeon Kim
Oncotarget. 2017 Jun 20; 8(25): 41091–41101. Published online 2017 Apr 12. doi: 10.18632/oncotarget.17056
PMCID:
PMC5522218
AbstractArticlePDF–3.1M
2.
Prognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer
Hidenori Takahashi, Toshiaki Ishikawa, Megumi Ishiguro, Satoshi Okazaki, Kaoru Mogushi, Hirotoshi Kobayashi, Satoru Iida, Hiroshi Mizushima, Hiroshi Tanaka, Hiroyuki Uetake, Kenichi Sugihara
BMC Cancer. 2015; 15: 794. Published online 2015 Oct 24. doi: 10.1186/s12885-015-1783-y
PMCID:
PMC4619995
AbstractArticlePDF–3.8M
3.
Antisense display--a method for functional gene screening: evaluation in a cell-free system and isolation of angiogenesis-related genes.
H Yonekura, H Migita, S Sakurai, H Wang, S Harada, M J Abedin, S Yamagishi, H Yamamoto
Nucleic Acids Res. 1999 Jul 1; 27(13): 2591–2600. doi: 10.1093/nar/27.13.2591
PMCID:
PMC148466
SummaryPDF–576K
4.
TDP-43 and NOVA-1 RNA-binding proteins as competitive splicing regulators of the schizophrenia-associated TNIK gene
Valentina Gumina, Claudia Colombrita, Claudia Fallini, Patrizia Bossolasco, Anna Maria Maraschi, John E. Landers, Vincenzo Silani, Antonia Ratti
Biochim Biophys Acta Gene Regul Mech. Author manuscript; available in PMC 2021 Jan 21.
Published in final edited form as: Biochim Biophys Acta Gene Regul Mech. 2019 Sep; 1862(9): 194413. Published online 2019 Aug 2. doi: 10.1016/j.bbagrm.2019.194413
PMCID:
PMC7818381
AbstractArticlePDF–1.7M
5.
Regulation of glioma migration and invasion via modification of Rap2a activity by the ubiquitin ligase Nedd4-1
Lei Wang, Bingxin Zhu, Shiquan Wang, Yuxuan Wu, Wenjian Zhan, Shao Xie, Hengliang Shi, Rutong Yu
Oncol Rep. 2017 May; 37(5): 2565–2574. Published online 2017 Apr 11. doi: 10.3892/or.2017.5572
PMCID:
PMC5428538
AbstractArticlePDF–814K
6.
TNIK inhibition abrogates colorectal cancer stemness
Mari Masuda, Yuko Uno, Naomi Ohbayashi, Hirokazu Ohata, Ayako Mimata, Mutsuko Kukimoto-Niino, Hideki Moriyama, Shigeki Kashimoto, Tomoko Inoue, Naoko Goto, Koji Okamoto, Mikako Shirouzu, Masaaki Sawa, Tesshi Yamada
Nat Commun. 2016; 7: 12586. Published online 2016 Aug 26. doi: 10.1038/ncomms12586
PMCID:
PMC5007443
AbstractArticlePDF–3.3M
7.
The kinase TNIK is an essential activator of Wnt target genes
Tokameh Mahmoudi, Vivian S W Li, Ser Sue Ng, Nadia Taouatas, Robert G J Vries, Shabaz Mohammed, Albert J Heck, Hans Clevers
EMBO J. 2009 Nov 4; 28(21): 3329–3340. Published online 2009 Oct 8. doi: 10.1038/emboj.2009.285
PMCID:
PMC2776109
AbstractArticlePDF–1.6M
8.
Regulation of Rap2A by the Ubiquitin Ligase Nedd4-1 Controls Neurite Development
Hiroshi Kawabe, Antje Neeb, Kalina Dimova, Samuel M. Young, Jr., Michiko Takeda, Shutaro Katsurabayashi, Miso Mitkovski, Oxana A. Malakhova, Dong-Er Zhang, Masato Umikawa, Ken-ichi Kariya, Sandra Goebbels, Klaus-Armin Nave, Christian Rosenmund, Olaf Jahn, JeongSeop Rhee, Nils Brose
Neuron. Author manuscript; available in PMC 2011 Feb 11.
Published in final edited form as: Neuron. 2010 Feb 11; 65(3): 358–372. doi: 10.1016/j.neuron.2010.01.007
PMCID:
PMC2825371
AbstractArticlePDF–3.6M
9.
A Genome-Wide Association Study of Schizophrenia Using Brain Activation as a Quantitative Phenotype
Steven G. Potkin, Jessica A. Turner, Guia Guffanti, Anita Lakatos, James H. Fallon, Dana D. Nguyen, Daniel Mathalon, Judith Ford, John Lauriello, Fabio Macciardi, FBIRN
Schizophr Bull. 2009 Jan; 35(1): 96–108. Published online 2008 Nov 20. doi: 10.1093/schbul/sbn155
PMCID:
PMC2643953
AbstractArticlePDF–1.5M
10.
The Germinal Center Kinase TNIK Is Required for Canonical NF-κB and JNK Signaling in B-Cells by the EBV Oncoprotein LMP1 and the CD40 Receptor
Anna Shkoda, Jennifer A. Town, Janine Griese, Michael Romio, Hakan Sarioglu, Thomas Knöfel, Fabian Giehler, Arnd Kieser
PLoS Biol. 2012 Aug; 10(8): e1001376. Published online 2012 Aug 14. doi: 10.1371/journal.pbio.1001376
PMCID:
PMC3419181
AbstractArticlePDF–1.3M
11.
Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project
Guillaume Lettre, Cameron D. Palmer, Taylor Young, Kenechi G. Ejebe, Hooman Allayee, Emelia J. Benjamin, Franklyn Bennett, Donald W. Bowden, Aravinda Chakravarti, Al Dreisbach, Deborah N. Farlow, Aaron R. Folsom, Myriam Fornage, Terrence Forrester, Ervin Fox, Christopher A. Haiman, Jaana Hartiala, Tamara B. Harris, Stanley L. Hazen, Susan R. Heckbert, Brian E. Henderson, Joel N. Hirschhorn, Brendan J. Keating, Stephen B. Kritchevsky, Emma Larkin, Mingyao Li, Megan E. Rudock, Colin A. McKenzie, James B. Meigs, Yang A. Meng, Tom H. Mosley, Jr., Anne B. Newman, Christopher H. Newton-Cheh, Dina N. Paltoo, George J. Papanicolaou, Nick Patterson, Wendy S. Post, Bruce M. Psaty, Atif N. Qasim, Liming Qu, Daniel J. Rader, Susan Redline, Muredach P. Reilly, Alexander P. Reiner, Stephen S. Rich, Jerome I. Rotter, Yongmei Liu, Peter Shrader, David S. Siscovick, W. H. Wilson Tang, Herman A. Taylor, Jr., Russell P. Tracy, Ramachandran S. Vasan, Kevin M. Waters, Rainford Wilks, James G. Wilson, Richard R. Fabsitz, Stacey B. Gabriel, Sekar Kathiresan, Eric Boerwinkle
PLoS Genet. 2011 Feb; 7(2): e1001300. Published online 2011 Feb 10. doi: 10.1371/journal.pgen.1001300
PMCID:
PMC3037413
AbstractArticlePDF–423K
12.
HENA, heterogeneous network-based data set for Alzheimer’s disease
Elena Sügis, Jerome Dauvillier, Anna Leontjeva, Priit Adler, Valerie Hindie, Thomas Moncion, Vincent Collura, Rachel Daudin, Yann Loe-Mie, Yann Herault, Jean-Charles Lambert, Henning Hermjakob, Tal Pupko, Jean-Christophe Rain, Ioannis Xenarios, Jaak Vilo, Michel Simonneau, Hedi Peterson
Sci Data. 2019; 6: 151. Published online 2019 Aug 14. doi: 10.1038/s41597-019-0152-0
PMCID:
PMC6694132
AbstractArticlePDF–2.8M
13.
Proximity Interactions Among Centrosome Components Identify Regulators of Centriole Duplication
Elif Nur Firat-Karalar, Navin Rauniyar, John R. Yates, III, Tim Stearns
Curr Biol. Author manuscript; available in PMC 2015 Mar 17.
Published in final edited form as: Curr Biol. 2014 Mar 17; 24(6): 664–670. Published online 2014 Mar 6. doi: 10.1016/j.cub.2014.01.067
PMCID:
PMC4004176
AbstractArticlePDF–1.4M
14.
Molecular Genetics of Successful Smoking Cessation: Convergent Genome-Wide Association Study Results
George R. Uhl, Qing-Rong Liu, Tomas Drgon, Catherine Johnson, Donna Walther, Jed E. Rose, Sean P. David, Ray Niaura, Caryn Lerman
Arch Gen Psychiatry. Author manuscript; available in PMC 2008 Jun 17.
Published in final edited form as: Arch Gen Psychiatry. 2008 Jun; 65(6): 683–693. doi: 10.1001/archpsyc.65.6.683
PMCID:
PMC2430596
AbstractArticlePDF–1.0M
15.
LZTR1 is a regulator of RAS ubiquitination and signaling
Johannes W. Bigenzahn, Giovanna M. Collu, Felix Kartnig, Melanie Pieraks, Gregory I. Vladimer, Leonhard X. Heinz, Vitaly Sedlyarov, Fiorella Schischlik, Astrid Fauster, Manuele Rebsamen, Katja Parapatics, Vincent A. Blomen, André C. Müller, Georg E. Winter, Robert Kralovics, Thijn R. Brummelkamp, Marek Mlodzik, Giulio Superti-Furga
Science. Author manuscript; available in PMC 2019 Oct 15.
Published in final edited form as: Science. 2018 Dec 7; 362(6419): 1171–1177. Published online 2018 Nov 15. doi: 10.1126/science.aap8210
PMCID:
PMC6794158
AbstractArticlePDF–1.9M
16.
Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage
Hongli An, Lu Yang, Chen Wang, Zhixue Gan, Haihui Gu, Tao Zhang, Xin Huang, Yan Liu, Yufeng Li, Shing-Jyh Chang, Jianghua Lai, Ya-Bin Li, Su Chen, Fang-Lin Sun
Mol Cell Biol. 2017 Mar 15; 37(6): e00419-16. Prepublished online 2016 Dec 28. Published online 2017 Mar 1. doi: 10.1128/MCB.00419-16
PMCID:
PMC5335506
AbstractArticlePDF–4.8M
17.
Endogenous Cell Type-Specific DISC1 Interactomes Reveal Protein Networks Associated to Neurodevelopmental Disorders
Brent Wilkinson, Oleg Evgrafov, DongQing Zheng, Nicolas Hartel, James A. Knowles, Nicholas A. Graham, Justin Ichida, Marcelo P. Coba
Biol Psychiatry. Author manuscript; available in PMC 2020 Feb 15.
Published in final edited form as: Biol Psychiatry. 2019 Feb 15; 85(4): 305–316. Published online 2018 May 23. doi: 10.1016/j.biopsych.2018.05.009
PMCID:
PMC6251761
AbstractArticlePDF–1.6M
18.
Image-Based Genome-Wide siRNA Screen Identifies Selective Autophagy Factors
Anthony Orvedahl, Rhea Sumpter, Jr., Guanghua Xiao, Aylwin Ng, Zhongju Zou, Yi Tang, Masahiro Narimatsu, Christopher Gilpin, Qihua Sun, Michael Roth, Christian V. Forst, Jeffrey L. Wrana, Ying E. Zhang, Katherine Luby-Phelps, Ramnik Xavier, Yang Xie, Beth Levine
Nature. Author manuscript; available in PMC 2012 Jun 1.
Published in final edited form as: Nature. 2011 Dec 1; 480(7375): 113–117. doi: 10.1038/nature10546
PMCID:
PMC3229641
AbstractArticlePDF–2.3M
19.
Interactomes of Glycogen Synthase Kinase-3 Isoforms
Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett
J Proteome Res. 2023 Mar 3; 22(3): 977–989. Published online 2023 Feb 13. doi: 10.1021/acs.jproteome.2c00825
PMCID:
PMC9990120
AbstractArticlePDF–3.7M
20.
MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
Gayoung Seo, Han Han, Rebecca Elizabeth Vargas, Bing Yang, Xu Li, Wenqi Wang
Cell Rep. Author manuscript; available in PMC 2020 Jul 25.
Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107860. doi: 10.1016/j.celrep.2020.107860
PMCID:
PMC7382313
AbstractArticlePDF–2.6M

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