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Select item 83681021.

Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1

Chaoyun Pan, JiHoon Kang, Jung Seok Hwang, Jie Li, Austin C. Boese, Xu Wang, Likun Yang, Titus J. Boggon, Georgia Z. Chen, Nabil F. Saba, Dong M. Shin, Kelly R. Magliocca, Lingtao Jin, Sumin Kang

Nat Commun. 2021; 12: 4960. Published online 2021 Aug 16. doi: 10.1038/s41467-021-24845-8

PMCID:: PMC8368102

Abstract Article PDF–3.4M

Select item 109485582.

USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells

Janardhan Keshav Karapurkar, Jencia Carminha Colaco, Bharathi Suresh, Apoorvi Tyagi, Sang Hyeon Woo, Won-Jun Jo, Nare Ko, Vijai Singh, Seok-Ho Hong, Seung Jun Oh, Kye-Seong Kim, Suresh Ramakrishna

Cell Mol Life Sci. 2024 Dec; 81(1): 145. Published online 2024 Mar 18. doi: 10.1007/s00018-024-05187-2

PMCID:: PMC10948558

Abstract Article PDF–10M

Select item 108541523.

CircMAST1 inhibits cervical cancer progression by hindering the N4-acetylcytidine modification of YAP mRNA

Chunyu Zhang, Li Yuan, Qiaojian Zou, Caixia Shao, Yan Jia, Jiaying Li, Yan Liao, Xueyuan Zhao, Weijia Wen, Xu Jing, Guofen Yang, Wei Wang, Hongye Jiang, Shuzhong Yao

Cell Mol Biol Lett. 2024; 29: 25. Published online 2024 Feb 8. doi: 10.1186/s11658-024-00540-6

PMCID:: PMC10854152

Abstract Article PDF–8.3M

Select item 72629024.

MAST1 modulates neuronal differentiation and cell cycle exit via P27 in neuroblastoma cells

Tianrui Jing, Jing Ma, Huanqiang Zhao, Jin Zhang, Nan Jiang, Duan Ma

FEBS Open Bio. 2020 Jun; 10(6): 1104–1114. Published online 2020 Apr 29. doi: 10.1002/2211-5463.12860

PMCID:: PMC7262902

Abstract Article PDF–2.3M

Select item 95271185.

E3 Ubiquitin Ligase CHIP Inhibits the Interaction between Hsp90β and MAST1 to Repress Radiation Resistance in Non-Small-Cell Lung Cancer Stem Cells

Bo Tan, Jingwei Zhang, Wen Wang, Haibo Ma, Yuanyuan Yang

Stem Cells Int. 2022; 2022: 2760899. Published online 2022 Sep 20. doi: 10.1155/2022/2760899

PMCID:: PMC9527118

Abstract Article PDF–2.8M

Select item 32336546.

Functionally Recurrent Rearrangements of the MAST Kinase and Notch Gene Families in Breast Cancer

Dan R. Robinson, Shanker Kalyana-Sundaram, Yi-Mi Wu, Sunita Shankar, Xuhong Cao, Bushra Ateeq, Irfan A. Asangani, Matthew Iyer, Christopher A. Maher, Catherine S. Grasso, Robert J. Lonigro, Michael Quist, Javed Siddiqui, Rohit Mehra, Xiaojun Jing, Thomas J. Giordano, Michael S. Sabel, Celina G. Kleer, Nallasivam Palanisamy, Rachael Natrajan, Maryou B. Lambros, Jorge S. Reis-Filho, Chandan Kumar-Sinha, Arul M. Chinnaiyan

Nat Med. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Nat Med. 2011 Dec; 17(12): 1646–1651. Published online 2011 Nov 20. doi: 10.1038/nm.2580

PMCID:: PMC3233654

Abstract Article PDF–1.7M

Select item 67632597.

Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation

Chaoyun Pan, Jaemoo Chun, Dan Li, Austin C. Boese, Jie Li, JiHoon Kang, Anna Umano, Yunhan Jiang, Lina Song, Kelly R. Magliocca, Zhuo G. Chen, Nabil F. Saba, Dong M. Shin, Taofeek K. Owonikoko, Sagar Lonial, Lingtao Jin, Sumin Kang

J Clin Invest. 2019 Oct 1; 129(10): 4110–4123. Published online 2019 Aug 26. doi: 10.1172/JCI125963

PMCID:: PMC6763259

Abstract Article PDF–8.2M

Select item 86241058.

PDZ-Containing Proteins Targeted by the ACE2 Receptor

Célia Caillet-Saguy, Nicolas Wolff

Viruses. 2021 Nov; 13(11): 2281. Published online 2021 Nov 15. doi: 10.3390/v13112281

PMCID:: PMC8624105

Abstract Article PDF–754K

Select item 64366229.

Mutations in MAST1 cause mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations

Ratna Tripathy, Ines Leca, Tessa van Dijk, Janneke Weiss, Bregje W van Bon, Maria Christina Sergaki, Thomas Gstrein, Martin Breuss, Guoling Tian, Nadia Bahi-Buisson, Alexander R. Paciorkowski, Alistair Pagnamenta, Andrea Wenninger-Weinzier, Maria Fernanda Martinez-Reza, Lukas Landler, Stefano Lise, Jenny C Taylor, Gaetano Terrone, Giuseppina Vitiello, Ennio Del Giudice, Nicola Brunetti-Pierri, Alessandra D’Amico, Alexandre Reymond, Norine Voisin, Jonathan A. Bernstein, Ellyn Farrelly, Usha Kini, Thomas A. Leonard, Stéphanie Valence, Lydie Burglen, Linlea Armstrong, Susan M. Hiatt, Gregory M. Cooper, Kimberly A Aldinger, William B Dobyns, Ghayda Mirzaa, Tyler Mark Pierson, Frank Baas, Jamel Chelly, Nicholas J. Cowan, David Anthony Keays

Neuron. Author manuscript; available in PMC 2019 Dec 19.

Published in final edited form as: Neuron. 2018 Dec 19; 100(6): 1354–1368.e5. Published online 2018 Nov 15. doi: 10.1016/j.neuron.2018.10.044

PMCID:: PMC6436622

Abstract Article PDF–3.6M

Select item 642461110.

Rewiring of RSK-PDZ interactome by linear motif phosphorylation

Gergő Gógl, Beáta Biri-Kovács, Fabien Durbesson, Pau Jane, Yves Nomine, Camille Kostmann, Viktória Bilics, Márton Simon, Attila Reményi, Renaud Vincentelli, Gilles Trave, László Nyitray

J Mol Biol. Author manuscript; available in PMC 2020 Mar 15.

Published in final edited form as: J Mol Biol. 2019 Mar 15; 431(6): 1234–1249. Published online 2019 Feb 3. doi: 10.1016/j.jmb.2019.01.038

PMCID:: PMC6424611

Abstract Article PDF–2.6M

Select item 452198111.

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay

Renaud Vincentelli, Katja Luck, Juline Poirson, Jolanta Polanowska, Julie Abdat, Marilyne Blémont, Jeremy Turchetto, François Iv, Kevin Ricquier, Marie-Laure Straub, Anne Forster, Patricia Cassonnet, Jean-Paul Borg, Yves Jacob, Murielle Masson, Yves Nominé, Jérôme Reboul, Nicolas Wolff, Sebastian Charbonnier, Gilles Travé

Nat Methods. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Nat Methods. 2015 Aug; 12(8): 787–793. Published online 2015 Jun 8. doi: 10.1038/nmeth.3438

PMCID:: PMC4521981

Abstract Article PDF–1.3M

Select item 874878912.

Systematic identification of NF90 target RNAs by iCLIP analysis

Valeria Lodde, Matteo Floris, Rachel Munk, Jennifer L. Martindale, Davide Piredda, Catello Mario Panu Napodano, Francesco Cucca, Sergio Uzzau, Kotb Abdelmohsen, Myriam Gorospe, Ji Heon Noh, M. Laura Idda

Sci Rep. 2022; 12: 364. Published online 2022 Jan 10. doi: 10.1038/s41598-021-04101-1

PMCID:: PMC8748789

Abstract Article PDF–4.2M

Select item 304485113.

Interactome mapping suggests new mechanistic details underlying Alzheimer's disease

Montserrat Soler-López, Andreas Zanzoni, Ricart Lluís, Ulrich Stelzl, Patrick Aloy

Genome Res. 2011 Mar; 21(3): 364–376. doi: 10.1101/gr.114280.110

PMCID:: PMC3044851

Abstract Article PDF–2.1M

Select item 1049982114.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 934857615.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 549522516.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 732206717.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 698120618.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 836418119.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 742732720.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

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