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Select item 111940931.

Proximal telomeric decompaction due to telomere shortening drives FOXC1-dependent myocardial senescence

Bin Li, Weiyao Xiong, Wu Zuo, Yuanyuan Shi, Teng Wang, Lingling Chang, Yueheng Wu, Heng Ma, Qian Bian, Alex C Y Chang

Nucleic Acids Res. 2024 Jun 24; 52(11): 6269–6284. Published online 2024 Apr 18. doi: 10.1093/nar/gkae274

PMCID:: PMC11194093

Abstract Article PDF–2.7M

Select item 90651552.

Somatic FOXC1 insertion mutation remodels the immune microenvironment and promotes the progression of childhood acute lymphoblastic leukemia

Yaping Wang, Xiaopeng Ma, Jie Huang, Xiaoyun Yang, Meiyun Kang, Xiaoyan Sun, Huimin Li, Yijun Wu, Heng Zhang, Yuting Zhu, Yao Xue, Yongjun Fang

Cell Death Dis. 2022 May; 13(5): 431. Published online 2022 May 3. doi: 10.1038/s41419-022-04873-y

PMCID:: PMC9065155

Abstract Article PDF–8.1M

Select item 89490763.

Variable Anterior Segment Dysgenesis and Cardiac Anomalies Caused by a Novel Truncating Variant of FOXC1

Mariya R. Ahmed, Saumil Sethna, Laura A. Krueger, Michael B. Yang, Robert B. Hufnagel

Genes (Basel) 2022 Mar; 13(3): 411. Published online 2022 Feb 24. doi: 10.3390/genes13030411

PMCID:: PMC8949076

Abstract Article PDF–26M

Select item 83876534.

干扰FOXC1逆转非小细胞肺癌吉非替尼耐药的作用

彭聪, 李盼, 杨明强, 陈丹扬, 黄渊锋

Zhongguo Fei Ai Za Zhi. 2021 Aug 20; 24(8): 538–547. Chinese. doi: 10.3779/j.issn.1009-3419.2021.103.11

PMCID:: PMC8387653

Abstract Article PDF–9.7M

Select item 82204075.

Phenotype expansion of heterozygous FOXC1 pathogenic variants toward involvement of congenital anomalies of the kidneys and urinary tract (CAKUT)

Chen-Han Wilfred Wu, Nina Mann, Makiko Nakayama, Dervla M. Connaughton, Rufeng Dai, Caroline M. Kolvenbach, Franziska Kause, Isabel Ottlewski, Chunyan Wang, Verena Klämbt, Steve Seltzsam, Ethan W. Lai, Aravind Selvin, Prabha Senguttuva, Olaf Bodamer, Deborah R. Stein, Sherif El Desoky, Jameela A. Kari, Velibor Tasic, Stuart B. Bauer, Shirlee Shril, Friedhelm Hildebrandt

Genet Med. Author manuscript; available in PMC 2021 Jun 23.

Published in final edited form as: Genet Med. 2020 Oct; 22(10): 1673–1681. Published online 2020 Jun 1. doi: 10.1038/s41436-020-0844-z

PMCID:: PMC8220407

Abstract Article PDF–995K

Select item 77911036.

Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis

Mingsen Li, Liqiong Zhu, Jiafeng Liu, Huaxing Huang, Huizhen Guo, Li Wang, Lingyu Li, Sijie Gu, Jieying Tan, Jing Zhong, Bowen Wang, Zhen Mao, Yong Fan, Chunqiao Liu, Jin Yuan, Hong Ouyang

Signal Transduct Target Ther. 2021; 6: 5. Published online 2021 Jan 8. doi: 10.1038/s41392-020-00378-2

PMCID:: PMC7791103

Abstract Article PDF–5.8M

Select item 75777997.

Forkhead Box C1 (FOXC1) Expression in Stromal Cells within the Microenvironment of T and NK Cell Lymphomas: Association with Tumor Dormancy and Activation

Ji Hae Nahm, Woo Ick Yang, Sun Och Yoon

Cancer Res Treat. 2020 Oct; 52(4): 1273–1282. Published online 2020 Jul 3. doi: 10.4143/crt.2020.032

PMCID:: PMC7577799

Abstract Article PDF–3.2M

Select item 74256318.

Childhood Glaucoma Genes and Phenotypes: Focus on FOXC1 mutations causing anterior segment dysgenesis and hearing loss

Angela C. Gauthier, Janey L. Wiggs

Exp Eye Res. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Exp Eye Res. 2020 Jan; 190: 107893. Published online 2019 Dec 11. doi: 10.1016/j.exer.2019.107893

PMCID:: PMC7425631

Abstract Article PDF–289K

Select item 71964669.

MIR‐138‐5P inhibits the progression of prostate cancer by targeting FOXC1

Hui Huang, Ying Xiong, Zhensheng Wu, Yuhui He, Xianglin Gao, Zhangyan Zhou, Tao Wang

Mol Genet Genomic Med. 2020 Apr; 8(4): e1193. Published online 2020 Feb 28. doi: 10.1002/mgg3.1193

PMCID:: PMC7196466

Abstract Article PDF–1.1M

Select item 584480210.

FOXC1-Induced Non-Canonical WNT5A-MMP7 Signaling Regulates Invasiveness in Triple-Negative Breast Cancer

Bingchen Han, Bo Zhou, Ying Qu, Bowen Gao, Yali Xu, Stacey Chung, Hisashi Tanaka, Wei Yang, Armando E. Giuliano, Xiaojiang Cui

Oncogene. Author manuscript; available in PMC 2018 Jun 18.

Published in final edited form as: Oncogene. 2018 Mar; 37(10): 1399–1408. Published online 2017 Dec 18. doi: 10.1038/s41388-017-0021-2

PMCID:: PMC5844802

Abstract Article PDF–1.6M

Select item 580221311.

Forkhead box protein C1 promotes cell proliferation and invasion in human cervical cancer

Lu Wang, Lulu Chai, Qingchun Ji, Rongjie Cheng, Jiao Wang, Shiyu Han

Mol Med Rep. 2018 Mar; 17(3): 4392–4398. Published online 2018 Jan 11. doi: 10.3892/mmr.2018.8423

PMCID:: PMC5802213

Abstract Article PDF–1.4M

Select item 565200012.

FOXC1: an emerging marker and therapeutic target for cancer

Bingchen Han, Neil Bhowmick, Ying Qu, Stacey Chung, Armando E. Giuliano, Xiaojiang Cui

Oncogene. Author manuscript; available in PMC 2017 Oct 23.

Published in final edited form as: Oncogene. 2017 Jul 13; 36(28): 3957–3963. Published online 2017 Mar 13. doi: 10.1038/onc.2017.48

PMCID:: PMC5652000

Abstract Article PDF–683K

Select item 543882413.

FOXC1 overexpression is a marker of poor response to anthracycline-based adjuvant chemotherapy in sporadic triple-negative breast cancer

Y. L. Xu, R. Yao, J. Li, Y. D. Zhou, F. Mao, B. Pan, Q. Sun

Cancer Chemother Pharmacol. 2017; 79(6): 1205–1213. Published online 2017 May 10. doi: 10.1007/s00280-017-3319-4

PMCID:: PMC5438824

Abstract Article PDF–829K

Select item 539958514.

Tumor Hypoxia Regulates Forkhead Box C1 to Promote Lung Cancer Progression

Yu-Jung Lin, Woei-Cherng Shyu, Chi-Wei Chang, Chi-Chung Wang, Chung-Pu Wu, Hsu-Tung Lee, Liang-Jwu Chen, Chia-Hung Hsieh

Theranostics. 2017; 7(5): 1177–1191. Published online 2017 Mar 5. doi: 10.7150/thno.17895

PMCID:: PMC5399585

Abstract Article PDF–2.4M

Select item 534277315.

FOXC1 identifies basal-like breast cancer in a hereditary breast cancer cohort

Jeff Johnson, Michael Choi, Farnaz Dadmanesh, Bingchen Han, Ying Qu, Yi Yu-Rice, Xiao Zhang, Sanjay Bagaria, Clive Taylor, Armando E. Giuliano, Farin Amersi, Xiaojiang Cui

Oncotarget. 2016 Nov 15; 7(46): 75729–75738. Published online 2016 Sep 30. doi: 10.18632/oncotarget.12370

PMCID:: PMC5342773

Abstract Article PDF–2.2M

Select item 496312716.

A Novel Homozygous Mutation in FOXC1 Causes Axenfeld Rieger Syndrome with Congenital Glaucoma

Shazia Micheal, Sorath Noorani Siddiqui, Saemah Nuzhat Zafar, Cristina Villanueva-Mendoza, Vianney Cortés-González, Muhammad Imran Khan, Anneke I. den Hollander

PLoS One. 2016; 11(7): e0160016. Published online 2016 Jul 27. doi: 10.1371/journal.pone.0160016

PMCID:: PMC4963127

Abstract Article PDF–5.0M

Select item 493007917.

Rare FOXC1 variants in congenital glaucoma: identification of translation regulatory sequences

Cristina Medina-Trillo, José-Daniel Aroca-Aguilar, Carmen-Dora Méndez-Hernández, Laura Morales, Maite García-Antón, Julián García-Feijoo, Julio Escribano

Eur J Hum Genet. 2016 May; 24(5): 672–680. Published online 2015 Jul 29. doi: 10.1038/ejhg.2015.169

PMCID:: PMC4930079

Abstract Article PDF–2.1M

Select item 455419618.

Diagnosis of Basal-Like Breast Cancer Using a FOXC1-Based Assay

Tor W. Jensen, Tania Ray, Jinhua Wang, Xiaodong Li, Wesley Y. Naritoku, Bingchen Han, Frank Bellafiore, Sanjay P. Bagaria, Annie Qu, Xiaojiang Cui, Clive R. Taylor, Partha S. Ray

J Natl Cancer Inst. 2015 Aug; 107(8): djv148. Published online 2015 Jun 3. doi: 10.1093/jnci/djv148

PMCID:: PMC4554196

Abstract Article PDF–5.8M

Select item 396100619.

FOXC1 regulates the functions of human basal-like breast cancer cells by activating NF-κB signaling

Jinhua Wang, Partha S. Ray, Myung-Shin Sim, Xiao Zhen Zhou, Kun Ping Lu, Adrian V. Lee, Xin Lin, Sanjay P. Bagaria, Armando E. Giuliano, Xiaojiang Cui

Oncogene. Author manuscript; available in PMC 2014 Mar 20.

Published in final edited form as: Oncogene. 2012 Nov 8; 31(45): 4798–4802. Published online 2012 Jan 16. doi: 10.1038/onc.2011.635

PMCID:: PMC3961006

Abstract Article PDF–1023K

Select item 394427920.

Dysfunction of the stress-responsive FOXC1 transcription factor contributes to the earlier-onset glaucoma observed in Axenfeld-Rieger syndrome patients

Y A Ito, I S Goping, F Berry, M A Walter

Cell Death Dis. 2014 Feb; 5(2): e1069. Published online 2014 Feb 20. doi: 10.1038/cddis.2014.8

Correction in:: Cell Death Dis. 2014 Oct; 5(10): e1430.

PMCID:: PMC3944279

Abstract Article PDF–1.5M

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