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Select item 111055211.

Rab18: new insights into the function of an essential protein

Selma Yilmaz Dejgaard, John F. Presley

Cell Mol Life Sci. 2019 May; 76(10): 1935–1945. Published online 2019 Mar 4. doi: 10.1007/s00018-019-03050-3

PMCID:: PMC11105521

Abstract Article PDF–1.6M

Select item 107435512.

Rab18 Drift in Lipid Droplet and Endoplasmic Reticulum Interactions of Adipocytes under Obesogenic Conditions

Jaime López-Alcalá, M. Carmen Soler-Vázquez, Carmen Tercero-Alcázar, Julia Sánchez-Ceinos, Rocío Guzmán-Ruiz, María M. Malagón, Ana Gordon

Int J Mol Sci. 2023 Dec; 24(24): 17177. Published online 2023 Dec 6. doi: 10.3390/ijms242417177

PMCID:: PMC10743551

Abstract Article PDF–4.1M

Select item 62329643.

Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells

Christina B. K. Jayson, Henning Arlt, Alexander W. Fischer, Zon Weng Lai, Robert V. Farese, Jr., Tobias C. Walther

Mol Biol Cell. 2018 Aug 15; 29(17): 2045–2054. doi: 10.1091/mbc.E18-05-0282

PMCID:: PMC6232964

Abstract Article PDF–3.4M

Select item 56949494.

COPI–TRAPPII activates Rab18 and regulates its lipid droplet association

Chunman Li, Xiaomin Luo, Shan Zhao, Gavin KY Siu, Yongheng Liang, Hsiao Chang Chan, Ayano Satoh, Sidney SB Yu

EMBO J. 2017 Feb 15; 36(4): 441–457. Published online 2016 Dec 21. doi: 10.15252/embj.201694866

PMCID:: PMC5694949

Abstract Article PDF–7.2M

Select item 88062765.

Rab18 interacted with V-set and immunoglobulin domain-containing 4 (VSIG4) to involve in the apoptosis of glioma and the sensitivity to temozolomide

Kai Yang, Zhi Wang

Bioengineered. 2021; 12(1): 1391–1402. Published online 2021 Apr 27. doi: 10.1080/21655979.2021.1919012

PMCID:: PMC8806276

Abstract Article PDF–4.0M

Select item 73375066.

Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum

Noemi Antonella Guadagno, Azzurra Margiotta, Synne Arstad Bjørnestad, Linda Hofstad Haugen, Ingrid Kjos, Xiaochun Xu, Xian Hu, Oddmund Bakke, Felix Margadant, Cinzia Progida

J Cell Biol. 2020 Jul 6; 219(7): e201809020. Published online 2020 Jun 11. doi: 10.1083/jcb.201809020

PMCID:: PMC7337506

Abstract Article PDF–5.9M

Select item 40543577.

Rab18 Facilitates Dengue Virus Infection by Targeting Fatty Acid Synthase to Sites of Viral Replication

Wei-Chun Tang, Ren-Jye Lin, Ching-Len Liao, Yi-Ling Lin

J Virol. 2014 Jun; 88(12): 6793–6804. doi: 10.1128/JVI.00045-14

PMCID:: PMC4054357

Abstract Article PDF–5.1M

Select item 46325058.

Warburg Micro syndrome is caused by RAB18 deficiency or dysregulation

Mark T. Handley, Sarah M. Carpanini, Girish R. Mali, Duska J. Sidjanin, Irene A. Aligianis, Ian J. Jackson, David R. FitzPatrick

Open Biol. 2015 Jun; 5(6): 150047. Published online 2015 Jun 10. doi: 10.1098/rsob.150047

PMCID:: PMC4632505

Abstract Article PDF–1.2M

Select item 30719209.

Loss-of-Function Mutations in RAB18 Cause Warburg Micro Syndrome

Danai Bem, Shin-Ichiro Yoshimura, Ricardo Nunes-Bastos, Frances F. Bond, Manju A. Kurian, Fatima Rahman, Mark T.W. Handley, Yavor Hadzhiev, Imran Masood, Ania A. Straatman-Iwanowska, Andrew R. Cullinane, Alisdair McNeill, Shanaz S. Pasha, Gail A. Kirby, Katharine Foster, Zubair Ahmed, Jenny E. Morton, Denise Williams, John M. Graham, William B. Dobyns, Lydie Burglen, John R. Ainsworth, Paul Gissen, Ferenc Müller, Eamonn R. Maher, Francis A. Barr, Irene A. Aligianis

Am J Hum Genet. 2011 Apr 8; 88(4): 499–507. doi: 10.1016/j.ajhg.2011.03.012

Correction in:: Am J Hum Genet. 2011 May 13; 88(5): 678.

PMCID:: PMC3071920

Abstract Article PDF–1.1M

Select item 373124610.

Rab18 Binds to Hepatitis C Virus NS5A and Promotes Interaction between Sites of Viral Replication and Lipid Droplets

Shadi Salloum, Hongliang Wang, Charles Ferguson, Robert G. Parton, Andrew W. Tai

PLoS Pathog. 2013 Aug; 9(8): e1003513. Published online 2013 Aug 1. doi: 10.1371/journal.ppat.1003513

PMCID:: PMC3731246

Abstract Article PDF–11M

Select item 1011960211.

Latent CSN-CRL complexes are crucial for curcumin-induced apoptosis and recruited during adipogenesis to lipid droplets via small GTPase RAB18

Dawadschargal Dubiel, Jing Wang, Roland Hartig, Supattra Chaithongyot, Wolfgang Dubiel, Michael Naumann

iScience. 2023 Apr 21; 26(4): 106468. Published online 2023 Mar 22. doi: 10.1016/j.isci.2023.106468

PMCID:: PMC10119602

Abstract Article PDF–6.6M

Select item 405072412.

Rab18 and a Rab18 GEF complex are required for normal ER structure

Andreas Gerondopoulos, Ricardo Nunes Bastos, Shin-ichiro Yoshimura, Rachel Anderson, Sarah Carpanini, Irene Aligianis, Mark T. Handley, Francis A. Barr

J Cell Biol. 2014 Jun 9; 205(5): 707–720. doi: 10.1083/jcb.201403026

PMCID:: PMC4050724

Abstract Article PDF–4.2M

Select item 385292613.

Loss-of-Function Mutations in TBC1D20 Cause Cataracts and Male Infertility in blind sterile Mice and Warburg Micro Syndrome in Humans

Ryan P. Liegel, Mark T. Handley, Adam Ronchetti, Stephen Brown, Lars Langemeyer, Andrea Linford, Bo Chang, Deborah J. Morris-Rosendahl, Sarah Carpanini, Renata Posmyk, Verity Harthill, Eamonn Sheridan, Ghada M.H. Abdel-Salam, Paulien A. Terhal, Francesca Faravelli, Patrizia Accorsi, Lucio Giordano, Lorenzo Pinelli, Britta Hartmann, Allison D. Ebert, Francis A. Barr, Irene A. Aligianis, Duska J. Sidjanin

Am J Hum Genet. 2013 Dec 5; 93(6): 1001–1014. doi: 10.1016/j.ajhg.2013.10.011

PMCID:: PMC3852926

Abstract Article PDF–2.8M

Select item 829252714.

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

Jiahui Xu, Xiaoli Yang, Qiaodan Deng, Cong Yang, Dong Wang, Guojuan Jiang, Xiaohong Yao, Xueyan He, Jiajun Ding, Jiankun Qiang, Juchuanli Tu, Rui zhang, Qun-Ying Lei, Zhi-min Shao, Xiuwu Bian, Ronggui Hu, Lixing Zhang, Suling Liu

Nat Commun. 2021; 12: 4413. Published online 2021 Jul 20. doi: 10.1038/s41467-021-24703-7

PMCID:: PMC8292527

Abstract Article PDF–6.5M

Select item 194513215.

The tumor suppressor PP2A Aβ regulates the RalA GTPase

Anna A. Sablina, Wen Chen, Jason D. Arroyo, Laura Corral, Melissa Hector, Sara E. Bulmer, James A. DeCaprio, William C. Hahn

Cell. Author manuscript; available in PMC 2008 Jun 1.

Published in final edited form as: Cell. 2007 Jun 1; 129(5): 969–982. doi: 10.1016/j.cell.2007.03.047

PMCID:: PMC1945132

Abstract Article PDF–1018K

Select item 549375516.

Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein

Laura A. Laviolette, Julien Mermoud, Isabel A. Calvo, Nicholas Olson, Myriam Boukhali, Ortrud K. Steinlein, Elisabeth Roider, Elke C. Sattler, Dachuan Huang, Bin Tean Teh, Mo Motamedi, Wilhelm Haas, Othon Iliopoulos

Nat Commun. 2017; 8: 15866. Published online 2017 Jun 28. doi: 10.1038/ncomms15866

PMCID:: PMC5493755

Abstract Article PDF–2.4M

Select item 287244317.

Mig-6 controls EGFR trafficking and suppresses gliomagenesis

Haoqiang Ying, Hongwu Zheng, Kenneth Scott, Ruprecht Wiedemeyer, Haiyan Yan, Carol Lim, Joseph Huang, Sabin Dhakal, Elena Ivanova, Yonghong Xiao, Hailei Zhang, Jian Hu, Jayne M. Stommel, Michelle A. Lee, An-Jou Chen, Ji-Hye Paik, Oreste Segatto, Cameron Brennan, Lisa A. Elferink, Y. Alan Wang, Lynda Chin, Ronald A. DePinho

Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15): 6912–6917. Published online 2010 Mar 29. doi: 10.1073/pnas.0914930107

PMCID:: PMC2872443

Abstract Article PDF–967K

Select item 561217318.

The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex

Meraj H. Khan, Siiri I. Salomaa, Guillaume Jacquemet, Umar Butt, Mitro Miihkinen, Takahiro Deguchi, Elena Kremneva, Pekka Lappalainen, Martin J. Humphries, Jeroen Pouwels

J Cell Sci. 2017 Sep 15; 130(18): 3094–3107. doi: 10.1242/jcs.200329

Correction in:: J Cell Sci. 2023 Oct 1; 136(19): jcs261581.

PMCID:: PMC5612173

Abstract Article

Select item 713853719.

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism

Johanna Hietamäki, Louise C Gregory, Sandy Ayoub, Anna-Pauliina Iivonen, Kirsi Vaaralahti, Xiaonan Liu, Nina Brandstack, Andrew J Buckton, Tiina Laine, Johanna Känsäkoski, Matti Hero, Päivi J Miettinen, Markku Varjosalo, Emma Wakeling, Mehul T Dattani, Taneli Raivio

J Clin Endocrinol Metab. 2020 Jun; 105(6): 1748–1758. Published online 2020 Feb 15. doi: 10.1210/clinem/dgaa078

PMCID:: PMC7138537

Abstract Article

Select item 295846820.

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

Shin-ichiro Yoshimura, Andreas Gerondopoulos, Andrea Linford, Daniel J. Rigden, Francis A. Barr

J Cell Biol. 2010 Oct 18; 191(2): 367–381. doi: 10.1083/jcb.201008051

PMCID:: PMC2958468

Abstract Article PDF–9.0M

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