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Select item 108631291.

Association between C10X polymorphism in the CARD8 gene and inflammatory markers in young healthy individuals in the LBA study

Karin Fransén, Ayako Hiyoshi, Geena V. Paramel, Anita Hurtig-Wennlöf

BMC Cardiovasc Disord. 2024; 24: 103. Published online 2024 Feb 13. doi: 10.1186/s12872-024-03765-7

PMCID:: PMC10863129

Abstract Article PDF–1.0M

Select item 103590952.

A human-specific motif facilitates CARD8 inflammasome activation after HIV-1 infection

Jessie Kulsuptrakul, Elizabeth A Turcotte, Michael Emerman, Patrick S Mitchell

eLife. 2023; 12: e84108. Published online 2023 Jul 7. doi: 10.7554/eLife.84108

PMCID:: PMC10359095

Abstract Article PDF–1.1M

Select item 92132473.

A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome

Jeffrey C. Hsiao, Atara R. Neugroschl, Ashley J. Chui, Cornelius Y. Taabazuing, Andrew R. Griswold, Qinghui Wang, Hsin-Che Huang, Elizabeth L. Orth-He, Daniel P. Ball, Giorgos Hiotis, Daniel A. Bachovchin

J Biol Chem. 2022 Jul; 298(7): 102032. Published online 2022 May 14. doi: 10.1016/j.jbc.2022.102032

PMCID:: PMC9213247

Abstract Article PDF–1.7M

Select item 79191994.

Genetic variation in CARD8, a gene coding for an NLRP3 inflammasome-associated protein, alters the genetic risk for diabetic nephropathy in the context of type 2 diabetes mellitus

Fotis Tsetsos, Athanasios Roumeliotis, Xanthippi Tsekmekidou, Sophia Alexouda, Stefanos Roumeliotis, Marios Theodoridis, Elias Thodis, Stylianos Panagoutsos, Nikolaos Papanas, Dimitrios Papazoglou, Kalliopi Kotsa, John G Yovos, Efstratios Maltezos, Ploumis Passadakis, Peristera Paschou, Marianthi Georgitsi

Diab Vasc Dis Res. 2020 Nov-Dec; 17(6): 1479164120970892. Published online 2020 Nov 8. doi: 10.1177/1479164120970892

PMCID:: PMC7919199

Abstract Article PDF–483K

Select item 76446835.

Expression of CARD8 in human atherosclerosis and its regulation of inflammatory proteins in human endothelial cells

Geena V. Paramel, Glykeria Karadimou, Anna Göthlin Eremo, Liza U. Ljungberg, Ulf Hedin, Peder S. Olofsson, Lasse Folkersen, Gabrielle Paulsson-Berne, Allan Sirsjö, Karin Fransén

Sci Rep. 2020; 10: 19108. Published online 2020 Nov 5. doi: 10.1038/s41598-020-73600-4

Correction in:: Sci Rep. 2021; 11: 8852.

PMCID:: PMC7644683

Abstract Article PDF–3.9M

Select item 75945956.

Activation of the CARD8 Inflammasome Requires a Disordered Region

Ashley J. Chui, Andrew R. Griswold, Cornelius Y. Taabazuing, Elizabeth L. Orth, Kuo Gai, Sahana D. Rao, Daniel P. Ball, Jeffrey C. Hsiao, Daniel A. Bachovchin

Cell Rep. Author manuscript; available in PMC 2020 Oct 29.

Published in final edited form as: Cell Rep. 2020 Oct 13; 33(2): 108264. doi: 10.1016/j.celrep.2020.108264

PMCID:: PMC7594595

Abstract Article PDF–1.4M

Select item 75278157.

CARD8 inflammasome activation triggers pyroptosis in human T cells

Andreas Linder, Stefan Bauernfried, Yiming Cheng, Manuel Albanese, Christophe Jung, Oliver T Keppler, Veit Hornung

EMBO J. 2020 Oct 1; 39(19): e105071. Published online 2020 Aug 25. doi: 10.15252/embj.2020105071

PMCID:: PMC7527815

Abstract Article PDF–1.5M

Select item 70551938.

Relationship of CARD8 Gene Polymorphisms with Susceptibility to Ankylosing Spondylitis: A Case-Control Study

Haitao Xu, Bo Li

Med Sci Monit. 2020; 26: e916935-1–e916935-7. Prepublished online 2020 Jan 22. Published online 2020 Feb 21. doi: 10.12659/MSM.916935

PMCID:: PMC7055193

Abstract Article PDF–328K

Select item 70360919.

A New Risk Polymorphism rs10403848 of CARD8 Significantly Associated with Psoriasis Vulgaris in Northeastern China

Pei Yu, Bingmei Liu, Siyu Hao, Ronggui Xing, Yuzhen Li

Biomed Res Int. 2020; 2020: 2867505. Published online 2020 Feb 11. doi: 10.1155/2020/2867505

PMCID:: PMC7036091

Abstract Article PDF–409K

Select item 623796110.

Association between caspase recruitment domain-containing protein 8 rs2043211 polymorphism and cardiovascular disease susceptibility: A systematic review and meta-analysis

Huijuan Huang, Qi Bi, Heng Wei, Beibei Luo, Yan He

Anatol J Cardiol. 2018 Aug; 20(2): 70–76. Published online 2018 Jul 24. doi: 10.14744/AnatolJCardiol.2018.32650

PMCID:: PMC6237961

Abstract Article PDF–134K

Select item 366088311.

The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces

Tengchuan Jin, Mo Huang, Patrick Smith, Jiansheng Jiang, T. Sam Xiao

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 May 1; 69(Pt 5): 482–487. Published online 2013 Apr 27. doi: 10.1107/S1744309113010075

PMCID:: PMC3660883

Abstract Article PDF–1.0M

Select item 360897212.

The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn’s disease

Francis Vasseur, Boualem Sendid, Franck Broly, Corinne Gower-Rousseau, Aurore Sarazin, Annie Standaert-Vitse, Jean-Frederic Colombel, Daniel Poulain, Thierry Jouault

BMC Med Genet. 2013; 14: 35. Published online 2013 Mar 18. doi: 10.1186/1471-2350-14-35

PMCID:: PMC3608972

Abstract Article PDF–357K

Select item 353093213.

CARD8 rs2043211 (p.C10X) Polymorphism Is Not Associated with Disease Susceptibility or Cardiovascular Events in Spanish Rheumatoid Arthritis Patients

Mercedes García-Bermúdez, Raquel López-Mejías, Carlos González-Juanatey, Alfonso Corrales, Santos Castañeda, Ana M. Ortiz, José A. Miranda-Filloy, Carmen Gómez-Vaquero, Benjamín Fernández-Gutiérrez, Alejandro Balsa, Dora Pascual-Salcedo, Ricardo Blanco, Javier Llorca, Javier Martín, Miguel A. González-Gay

DNA Cell Biol. 2013 Jan; 32(1): 28–33. doi: 10.1089/dna.2012.1836

PMCID:: PMC3530932

Abstract Article PDF–144K

Select item 272526514.

A Genome-wide In Vitro Bacterial-Infection Screen Reveals Human Variation in the Host Response Associated with Inflammatory Disease

Dennis C. Ko, Kajal P. Shukla, Christine Fong, Michael Wasnick, Mitchell J. Brittnacher, Mark M. Wurfel, Tarah D. Holden, Grant E. O'Keefe, Brian Van Yserloo, Joshua M. Akey, Samuel I. Miller

Am J Hum Genet. 2009 Aug 14; 85(2): 214–227. doi: 10.1016/j.ajhg.2009.07.012

PMCID:: PMC2725265

Abstract Article PDF–1017K

Select item 153861915.

TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells

Agnieszka Checinska, Giuseppe Giaccone, Bas SJ Hoogeland, Carlos G Ferreira, Jose A Rodriguez, Frank AE Kruyt

BMC Cancer. 2006; 6: 166. Published online 2006 Jun 23. doi: 10.1186/1471-2407-6-166

PMCID:: PMC1538619

Abstract Article PDF–419K

Select item 1052819316.

Tripping the wire: sensing of viral protease activity by CARD8 and NLRP1 inflammasomes

Lennice K. Castro, Matthew D. Daugherty

Curr Opin Immunol. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Curr Opin Immunol. 2023 Aug; 83: 102354. Published online 2023 Jun 11. doi: 10.1016/j.coi.2023.102354

PMCID:: PMC10528193

Abstract Article PDF–1004K

Select item 1004221617.

Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation

Elizabeth L. Orth-He, Hsin-Che Huang, Sahana D. Rao, Qinghui Wang, Qifeng Chen, Claire M. O’Mara, Ashley J. Chui, Michelle Saoi, Andrew R. Griswold, Abir Bhattacharjee, Daniel P. Ball, Justin R. Cross, Daniel A. Bachovchin

Cell Rep. Author manuscript; available in PMC 2023 Mar 27.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111965. Published online 2023 Jan 16. doi: 10.1016/j.celrep.2022.111965

PMCID:: PMC10042216

Abstract Article PDF–2.9M

Select item 996340118.

Association between NLRP3 rs10754558 and CARD8 rs2043211 Variants and Susceptibility to Chronic Kidney Disease

Antonella La Russa, Danilo Lofaro, Alberto Montesanto, Daniele La Russa, Gianluigi Zaza, Simona Granata, Michele Di Dio, Raffaele Serra, Michele Andreucci, Renzo Bonofiglio, Anna Perri

Int J Mol Sci. 2023 Feb; 24(4): 4184. Published online 2023 Feb 20. doi: 10.3390/ijms24044184

PMCID:: PMC9963401

Abstract Article PDF–533K

Select item 994213919.

The NLRP1 and CARD8 inflammasomes detect reductive stress

Qinghui Wang, Jeffrey C. Hsiao, Noah Yardeny, Hsin-Che Huang, Claire M. O’Mara, Elizabeth L. Orth-He, Daniel P. Ball, Ze Zhang, Daniel A. Bachovchin

Cell Rep. Author manuscript; available in PMC 2023 Feb 21.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111966. Published online 2023 Jan 16. doi: 10.1016/j.celrep.2022.111966

PMCID:: PMC9942139

Abstract Article PDF–3.4M

Select item 951168020.

Association of CARD8 Activating Polymorphism With Bone Erosion in Cholesteatoma Patients

Neel Sangal, John Yan, Jessica Pryor, Marcus L. Elias, Biju Joseph, Luis Ulloa, Robert W. Jyung

Laryngoscope. Author manuscript; available in PMC 2022 Sep 26.

Published in final edited form as: Laryngoscope. 2021 Feb; 131(2): E605–E611. Published online 2020 May 12. doi: 10.1002/lary.28741

PMCID:: PMC9511680

Abstract Article PDF–417K

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PMC Links for Gene (Select 22900) (55)
PMC
short-chain dehydrogenase [Globicatella sp. HMSC072A10]
short-chain dehydrogenase [Globicatella sp. HMSC072A10]
gi|1080265603|gb|OFK58550.1||gnl|WG S|HMPREF2811_05360

Protein
beta-hydroxyacyl-ACP dehydratase [Globicatella sp. HMSC072A10]
beta-hydroxyacyl-ACP dehydratase [Globicatella sp. HMSC072A10]
gi|1080265607|gb|OFK58554.1||gnl|WG S|HMPREF2811_05380

Protein
hypothetical protein WI47_32170 [Burkholderia cepacia]
hypothetical protein WI47_32170 [Burkholderia cepacia]
gi|976123708|gb|KVA62023.1||gnl|WGS |WI47_32170

Protein
hypothetical protein ECDEC4C_1677 [Escherichia coli DEC4C]
hypothetical protein ECDEC4C_1677 [Escherichia coli DEC4C]
gi|377946287|gb|EHV09969.1||gnl|WGS |ECDEC4C_1677

Protein

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