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Items: 1 to 20 of 98

1.
DIS3 depletion in multiple myeloma causes extensive perturbation in cell cycle progression and centrosome amplification
Vanessa K. Favasuli, Domenica Ronchetti, Ilaria Silvestris, Noemi Puccio, Giuseppina Fabbiano, Valentina Traini, Katia Todoerti, Silvia Erratico, Alessia Ciarrocchi, Valentina Fragliasso, Domenica Giannandrea, Francesca Tumiatti, Raffaella Chiaramonte, Yvan Torrente, Palma Finelli, Eugenio Morelli, Nikhil C. Munshi, Niccolò Bolli, Antonino Neri, Elisa Taiana
Haematologica. 2024 Jan 1; 109(1): 231–244. Published online 2023 Jul 13. doi: 10.3324/haematol.2023.283274
PMCID:
PMC10772536
AbstractArticlePDF–2.8M
2.
DIS3: The Enigmatic Gene in Multiple Myeloma
Yasuyo Ohguchi, Hiroto Ohguchi
Int J Mol Sci. 2023 Feb; 24(4): 4079. Published online 2023 Feb 17. doi: 10.3390/ijms24044079
PMCID:
PMC9958658
AbstractArticlePDF–1.5M
3.
Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism
Ilaria Gritti, Veronica Basso, Darawan Rinchai, Federica Corigliano, Silvia Pivetti, Marco Gaviraghi, Dalia Rosano, Davide Mazza, Sara Barozzi, Marco Roncador, Giovanni Parmigiani, Gaelle Legube, Dario Parazzoli, Davide Cittaro, Davide Bedognetti, Anna Mondino, Simona Segalla, Giovanni Tonon
EMBO J. 2022 Nov; 41(22): e108040. Published online 2022 Oct 10. doi: 10.15252/embj.2021108040
PMCID:
PMC9670201
AbstractArticlePDF–7.3M
4.
DIS3 mutations in multiple myeloma impact the transcriptional signature and clinical outcome
Katia Todoerti, Domenica Ronchetti, Vanessa Favasuli, Francesco Maura, Fortunato Morabito, Niccolò Bolli, Elisa Taiana, Antonino Neri
Haematologica. 2022 Apr 1; 107(4): 921–932. Published online 2021 May 6. doi: 10.3324/haematol.2021.278342
PMCID:
PMC8968896
AbstractArticlePDF–1.2M
5.
Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma
Maroulio Pertesi, Maxime Vallée, Xiaomu Wei, Maria V. Revuelta, Perrine Galia, Delphine Demangel, Javier Oliver, Matthieu Foll, Siwei Chen, Emeline Perrial, Laurent Garderet, Jill Corre, Xavier Leleu, Eileen M. Boyle, Olivier Decaux, Philippe Rodon, Brigitte Kolb, Borhane Slama, Philippe Mineur, Eric Voog, Catherine Le Bris, Jean Fontan, Michel Maigre, Marie Beaumont, Isabelle Azais, Hagay Sobol, Marguerite Vignon, Bruno Royer, Aurore Perrot, Jean-Gabriel Fuzibet, Véronique Dorvaux, Bruno Anglaret, Pascale Cony-Makhoul, Christian Berthou, Florence Desquesnes, Brigitte Pegourie, Serge Leyvraz, Laurent Mosser, Nicole Frenkiel, Karine Augeul-Meunier, Isabelle Leduc, Cécile Leyronnas, Laurent Voillat, Philippe Casassus, Claire Mathiot, Nathalie Cheron, Etienne Paubelle, Philippe Moreau, Yves–Jean Bignon, Bertrand Joly, Pascal Bourquard, Denis Caillot, Hervé Naman, Sophie Rigaudeau, Gérald Marit, Margaret Macro, Isabelle Lambrecht, Manuel Cliquennois, Laure Vincent, Philippe Helias, Hervé Avet-Loiseau, Victor Moreno, Rui Manuel Reis, Judit Varkonyi, Marcin Kruszewski, Annette Juul Vangsted, Artur Jurczyszyn, Jan Maciej Zaucha, Juan Sainz, Malgorzata Krawczyk-Kulis, Marzena Wątek, Matteo Pelosini, Elzbieta Iskierka-Jażdżewska, Norbert Grząśko, Joaquin Martinez-Lopez, Andrés Jerez, Daniele Campa, Gabriele Buda, Fabienne Lesueur, Marek Dudziński, Ramón García-Sanz, Arnon Nagler, Marcin Rymko, Krzysztof Jamroziak, Aleksandra Butrym, Federico Canzian, Ofure Obazee, Björn Nilsson, Robert J. Klein, Steven M. Lipkin, James D. McKay, Charles Dumontet
Leukemia. 2019; 33(9): 2324–2330. Published online 2019 Apr 9. doi: 10.1038/s41375-019-0452-6
PMCID:
PMC6756025
ArticlePDF–1.3M
6.
DIS3 isoforms vary in their endoribonuclease activity and are differentially expressed within haematological cancers
Sophie R. Robinson, Sandra C. Viegas, Rute G. Matos, Susana Domingues, Marisa Bedir, Helen J.S. Stewart, Timothy J. Chevassut, Antony W. Oliver, Cecilia M. Arraiano, Sarah F. Newbury
Biochem J. 2018 Jun 29; 475(12): 2091–2105. Prepublished online 2018 May 25. Published online 2018 Jun 29. doi: 10.1042/BCJ20170962
PMCID:
PMC6024818
AbstractArticlePDF–12M
7.
Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression
Jason W. Hoskins, Abdisamad Ibrahim, Mickey A. Emmanuel, Sarah M. Manmiller, Yinglun Wu, Maura O’Neill, Jinping Jia, Irene Collins, Mingfeng Zhang, Janelle V. Thomas, Lauren M. Rost, Sudipto Das, Hemang Parikh, Jefferson M. Haake, Gail L. Matters, Robert C. Kurtz, William R. Bamlet, Alison Klein, Rachael Stolzenberg-Solomon, Brian M. Wolpin, Ronit Yarden, Zhaoming Wang, Jill Smith, Sara H. Olson, Thorkell Andresson, Gloria M. Petersen, Laufey T. Amundadottir
Hum Mol Genet. 2016 Nov 1; 25(21): 4726–4738. Published online 2016 Aug 30. doi: 10.1093/hmg/ddw300
PMCID:
PMC5815622
AbstractArticlePDF–781K
8.
A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias
Marta Lionetti, Marzia Barbieri, Katia Todoerti, Luca Agnelli, Sonia Fabris, Giovanni Tonon, Simona Segalla, Ingrid Cifola, Eva Pinatel, Pierfrancesco Tassone, Pellegrino Musto, Luca Baldini, Antonino Neri
Oncotarget. 2015 Sep 22; 6(28): 26129–26141. Published online 2015 Jul 20. doi: 10.18632/oncotarget.4674
PMCID:
PMC4694891
AbstractArticlePDF–1.7M
9.
DIS3 Variants are Associated With Primary Ovarian Insufficiency: Importance of Transcription/Translation in Oogenesis
Erica Boiman Johnstone, Bushra Gorsi, Emily Coelho, Barry Moore, Ashley M Farr, Amber R Cooper, Elaine R Mardis, Aleksander Rajkovic, Clement Y Chow, Mark Yandell, Corrine K Welt
J Clin Endocrinol Metab. 2023 Sep; 108(9): 2330–2335. Published online 2023 Mar 3. doi: 10.1210/clinem/dgad126
PMCID:
PMC10686695
AbstractArticle
10.
RNA-regulatory exosome complex confers cellular survival to promote erythropoiesis
Charu Mehta, Isabela Fraga de Andrade, Daniel R Matson, Colin N Dewey, Emery H Bresnick
Nucleic Acids Res. 2021 Sep 20; 49(16): 9007–9025. Published online 2021 Jun 1. doi: 10.1093/nar/gkab367
PMCID:
PMC8450083
AbstractArticlePDF–7.9M
11.
Elimination of 01/A′–A0 pre-rRNA processing by-product in human cells involves cooperative action of two nuclear exosome-associated nucleases: RRP6 and DIS3
Kamil Kobyłecki, Karolina Drążkowska, Tomasz M. Kuliński, Andrzej Dziembowski, Rafał Tomecki
RNA. 2018 Dec; 24(12): 1677–1692. doi: 10.1261/rna.066589.118
PMCID:
PMC6239190
AbstractArticlePDF–4.9M
12.
Distinct and evolutionary conserved structural features of the human nuclear exosome complex
Piotr Gerlach, Jan M Schuller, Fabien Bonneau, Jérôme Basquin, Peter Reichelt, Sebastian Falk, Elena Conti
eLife. 2018; 7: e38686. Published online 2018 Jul 26. doi: 10.7554/eLife.38686
PMCID:
PMC6072439
AbstractArticlePDF–12M
13.
The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease
Sophie R. Robinson, Antony W. Oliver, Timothy J. Chevassut, Sarah F. Newbury
Biomolecules. 2015 Sep; 5(3): 1515–1539. Published online 2015 Jul 17. doi: 10.3390/biom5031515
PMCID:
PMC4598762
AbstractArticlePDF–3.6M
14.
MPP6 stimulates both RRP6 and DIS3 to degrade a specified subset of MTR4-sensitive substrates in the human nucleus
Naoko Fujiwara, Maki Shigemoto, Mizuki Hirayama, Ken-ichi Fujita, Shigeto Seno, Hideo Matsuda, Masami Nagahama, Seiji Masuda
Nucleic Acids Res. 2022 Aug 26; 50(15): 8779–8806. Published online 2022 Jul 29. doi: 10.1093/nar/gkac559
PMCID:
PMC9410898
AbstractArticlePDF–17M
15.
Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control
Lee Davidson, Laura Francis, Ross A. Cordiner, Joshua D. Eaton, Chris Estell, Sara Macias, Javier F. Cáceres, Steven West
Cell Rep. 2019 Mar 5; 26(10): 2779–2791.e5. Published online 2019 Mar 5. doi: 10.1016/j.celrep.2019.02.012
PMCID:
PMC6403362
AbstractArticlePDF–3.6M
16.
The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA
Simona Segalla, Silvia Pivetti, Katia Todoerti, Malgorzata Agata Chudzik, Erica Claudia Giuliani, Federico Lazzaro, Viviana Volta, Dejan Lazarevic, Giovanna Musco, Marco Muzi-Falconi, Antonino Neri, Stefano Biffo, Giovanni Tonon
Nucleic Acids Res. 2015 May 26; 43(10): 5182–5193. Published online 2015 Apr 29. doi: 10.1093/nar/gkv387
PMCID:
PMC4446438
AbstractArticlePDF–3.3M
17.
Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target
Rafal Tomecki, Karolina Drazkowska, Iwo Kucinski, Krystian Stodus, Roman J. Szczesny, Jakub Gruchota, Ewelina P. Owczarek, Katarzyna Kalisiak, Andrzej Dziembowski
Nucleic Acids Res. 2014 Jan; 42(2): 1270–1290. Published online 2013 Oct 21. doi: 10.1093/nar/gkt930
PMCID:
PMC3902924
AbstractArticlePDF–19M
18.
Post-transcriptional negative feedback regulation of proteostasis through the Dis3 ribonuclease and its disruption by polyQ-expanded Huntingtin
Ka-Yiu Edwin Kong, Ting-Ngai Felix Hung, Pui-Hei Marcus Man, Tin-Ning Wong, Tao Cheng, Dong-Yan Jin
Nucleic Acids Res. 2019 Nov 4; 47(19): 10040–10058. Published online 2019 Aug 20. doi: 10.1093/nar/gkz722
PMCID:
PMC6821268
AbstractArticlePDF–1.9M
19.
Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA
Michal Lubas, Christian K Damgaard, Rafal Tomecki, Dominik Cysewski, Torben Heick Jensen, Andrzej Dziembowski
EMBO J. 2013 Jul 3; 32(13): 1855–1868. Published online 2013 Jun 11. doi: 10.1038/emboj.2013.135
PMCID:
PMC3981170
AbstractArticle
20.
Addition of poly(A) and poly(A)-rich tails during RNA degradation in the cytoplasm of human cells
Shimyn Slomovic, Ella Fremder, Raymond H. G. Staals, Ger J. M. Pruijn, Gadi Schuster
Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16): 7407–7412. Published online 2010 Apr 5. doi: 10.1073/pnas.0910621107
PMCID:
PMC2867691
AbstractArticlePDF–906K

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