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Items: 1 to 20 of 39

1.
Anterograde trafficking of ciliary MAP kinase–like ICK/CILK1 by the intraflagellar transport machinery is required for intraciliary retrograde protein trafficking
Kentaro Nakamura, Tatsuro Noguchi, Mariko Takahara, Yoshihiro Omori, Takahisa Furukawa, Yohei Katoh, Kazuhisa Nakayama
J Biol Chem. 2020 Sep 18; 295(38): 13363–13376. Published online 2020 Jul 29. doi: 10.1074/jbc.RA120.014142
PMCID:
PMC7504932
AbstractArticlePDF–4.9M
2.
Functional Alterations in Ciliogenesis-Associated Kinase 1 (CILK1) that Result from Mutations Linked to Juvenile Myoclonic Epilepsy
Eric J. Wang, Casey D. Gailey, David L. Brautigan, Zheng Fu
Cells. 2020 Mar; 9(3): 694. Published online 2020 Mar 12. doi: 10.3390/cells9030694
PMCID:
PMC7140639
AbstractArticlePDF–1.7M
3.
Ciliogenesis associated kinase 1 (CILK1): targets and functions in various organ systems
Zheng Fu, Casey D. Gailey, Eric J. Wang, David L. Brautigan
FEBS Lett. Author manuscript; available in PMC 2020 Nov 1.
Published in final edited form as: FEBS Lett. 2019 Nov; 593(21): 2990–3002. Published online 2019 Sep 20. doi: 10.1002/1873-3468.13600
PMCID:
PMC6848764
AbstractArticlePDF–850K
4.
Intestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells
Zheng Fu, Jungeun Kim, Alda Vidrich, Thomas W. Sturgill, Steven M. Cohn
Am J Physiol Gastrointest Liver Physiol. 2009 Oct; 297(4): G632–G640. doi: 10.1152/ajpgi.00066.2009
PMCID:
PMC2763805
AbstractArticle
5.
Activation of a Nuclear Cdc2-Related Kinase within a Mitogen-Activated Protein Kinase-Like TDY Motif by Autophosphorylation and Cyclin-Dependent Protein Kinase-Activating Kinase
Zheng Fu, Melanie J. Schroeder, Jeffrey Shabanowitz, Philipp Kaldis, Kasumi Togawa, Anil K. Rustgi, Donald F. Hunt, Thomas W. Sturgill
Mol Cell Biol. 2005 Jul; 25(14): 6047–6064. doi: 10.1128/MCB.25.14.6047-6064.2005
PMCID:
PMC1168834
AbstractArticlePDF–1.3M
6.
Ciliogenesis-associated Kinase 1 Promotes Breast Cancer Cell Proliferation and Chemoresistance via Phosphorylating ERK1
Yanling He, Xinyuan Zhang, Weijun Pan, Jiebiao Zhang, Weiliang Zhu, Jian Zhang, Jian Shi
Int J Biol Sci. 2024; 20(7): 2403–2421. Published online 2024 Apr 8. doi: 10.7150/ijbs.87442
PMCID:
PMC11077371
AbstractArticlePDF–10M
7.
Ciliopathy-Associated Protein Kinase ICK Requires Its Non-Catalytic Carboxyl-Terminal Domain for Regulation of Ciliogenesis
Yoon Seon Oh, Eric J. Wang, Casey D. Gailey, David L. Brautigan, Benjamin L. Allen, Zheng Fu
Cells. 2019 Jul; 8(7): 677. Published online 2019 Jul 4. doi: 10.3390/cells8070677
PMCID:
PMC6678984
AbstractArticlePDF–1.5M
8.
Intestinal Cell Kinase Is a Novel Participant in Intestinal Cell Signaling Responses to Protein Malnutrition
David T. Bolick, Tufeng Chen, Luís Antonio O. Alves, Yixin Tong, Di Wu, Linwood T. Joyner, II, Reinaldo B. Oriá, Richard L. Guerrant, Zheng Fu
PLoS One. 2014; 9(9): e106902. Published online 2014 Sep 3. doi: 10.1371/journal.pone.0106902
PMCID:
PMC4153720
AbstractArticlePDF–2.6M
9.
A Multiplex Human Syndrome Implicates a Key Role for Intestinal Cell Kinase in Development of Central Nervous, Skeletal, and Endocrine Systems
Piya Lahiry, Jian Wang, John F. Robinson, Jacob P. Turowec, David W. Litchfield, Matthew B. Lanktree, Gregory B. Gloor, Erik G. Puffenberger, Kevin A. Strauss, Mildred B. Martens, David A. Ramsay, C. Anthony Rupar, Victoria Siu, Robert A. Hegele
Am J Hum Genet. 2009 Feb 13; 84(2): 134–147. doi: 10.1016/j.ajhg.2008.12.017
Correction in:
Am J Hum Genet. 2009 Jun 12; 84(6): 822.
PMCID:
PMC2668000
AbstractArticlePDF–2.0M
10.
CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner
Ying Yang, Niina Roine, Tomi P Mäkelä
EMBO Rep. 2013 Aug; 14(8): 741–747. Published online 2013 Jun 7. doi: 10.1038/embor.2013.80
PMCID:
PMC3736126
AbstractArticlePDF–739K
11.
Identification of Kinases Regulating Prostate Cancer Cell Growth Using an RNAi Phenotypic Screen
Hilary Whitworth, Shriti Bhadel, Melissa Ivey, Mark Conaway, Andrea Spencer, Ronald Hernan, Heather Holemon, Daniel Gioeli
PLoS One. 2012; 7(6): e38950. Published online 2012 Jun 27. doi: 10.1371/journal.pone.0038950
PMCID:
PMC3384611
AbstractArticlePDF–1.9M
12.
Intestinal Cell Kinase (ICK) Promotes Activation of mTOR Complex 1 (mTORC1) through Phosphorylation of Raptor Thr-908
Di Wu, Jessica R. Chapman, Lifu Wang, Thurl E. Harris, Jeffrey Shabanowitz, Donald F. Hunt, Zheng Fu
J Biol Chem. 2012 Apr 6; 287(15): 12510–12519. Published online 2012 Feb 22. doi: 10.1074/jbc.M111.302117
PMCID:
PMC3321000
AbstractArticlePDF–1.9M
13.
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to intraflagellar transport turnaround involving ICK/CILK1
Yuuki Satoda, Tatsuro Noguchi, Taiju Fujii, Aoi Taniguchi, Yohei Katoh, Kazuhisa Nakayama
Mol Biol Cell. 2022 Aug 1; 33(9): ar79. Published online 2022 Jul 21. doi: 10.1091/mbc.E22-03-0089
PMCID:
PMC9582636
AbstractArticlePDF–6.5M
14.
Isc10, an inhibitor of the Smk1 MAPK, prevents activation loop autophosphorylation and substrate phosphorylation through separate mechanisms
Abhimannyu Rimal, Thomas M. Swayne, Zeal P. Kamdar, Madison A. Tewey, Edward Winter
J Biol Chem. 2022 Oct; 298(10): 102450. Published online 2022 Sep 3. doi: 10.1016/j.jbc.2022.102450
PMCID:
PMC9558048
AbstractArticlePDF–1.2M
15.
Distinct Expression Patterns of ICK/MAK/MOK Protein Kinases in the Intestine Implicate Functional Diversity
Tufeng Chen, Di Wu, Christopher A. Moskaluk, Zheng Fu
PLoS One. 2013; 8(11): e79359. Published online 2013 Nov 7. doi: 10.1371/journal.pone.0079359
PMCID:
PMC3820702
AbstractArticlePDF–2.0M
16.
An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome
S. Paige Taylor, Michaela Kunova Bosakova, Miroslav Varecha, Lukas Balek, Tomas Barta, Lukas Trantirek, Iva Jelinkova, Ivan Duran, Iva Vesela, Kimberly N. Forlenza, Jorge H. Martin, Ales Hampl, University of Washington Center for Mendelian Genomics, Michael Bamshad, Deborah Nickerson, Margie L. Jaworski, Jieun Song, Hyuk Wan Ko, Daniel H. Cohn, Deborah Krakow, Pavel Krejci
Hum Mol Genet. 2016 Sep 15; 25(18): 3998–4011. Published online 2016 Jul 27. doi: 10.1093/hmg/ddw240
PMCID:
PMC5291234
AbstractArticlePDF–2.1M
17.
The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factors
Thomas W Sturgill, Paul B Stoddard, Steven M Cohn, Marty W Mayo
Mol Cancer. 2010; 9: 104. Published online 2010 May 11. doi: 10.1186/1476-4598-9-104
PMCID:
PMC2876993
AbstractArticlePDF–1.0M
18.
Identification of Yin-Yang Regulators and a Phosphorylation Consensus for Male Germ Cell-Associated Kinase (MAK)-Related Kinase
Zheng Fu, Katherine A. Larson, Raghu K. Chitta, Sirlester A. Parker, Benjamin E. Turk, Matthew W. Lawrence, Philipp Kaldis, Konstantin Galaktionov, Steven M. Cohn, Jeffrey Shabanowitz, Donald F. Hunt, Thomas W. Sturgill
Mol Cell Biol. 2006 Nov; 26(22): 8639–8654. Published online 2006 Sep 5. doi: 10.1128/MCB.00816-06
PMCID:
PMC1636783
AbstractArticlePDF–1.2M
19.
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport
Taro Chaya, Yoshihiro Omori, Ryusuke Kuwahara, Takahisa Furukawa
EMBO J. 2014 Jun 2; 33(11): 1227–1242. Published online 2014 May 5. doi: 10.1002/embj.201488175
PMCID:
PMC4198026
AbstractArticlePDF–2.7M
20.
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities
Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat
Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54
PMCID:
PMC3817404
AbstractArticlePDF–13M

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