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Select item 64625101.

WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial–mesenchymal transition

Wentao Deng, Audry Fernandez, Sarah L. McLaughlin, David J. Klinke, II

J Biol Chem. 2019 Apr 5; 294(14): 5261–5280. Published online 2019 Feb 5. doi: 10.1074/jbc.RA118.006122

PMCID:: PMC6462510

Abstract Article PDF–4.4M

Select item 63650432.

Non-canonical Wnt signaling contributes to ventilator-induced lung injury through upregulation of WISP1 expression

Yue-Feng Xia, Jing Chang, Jin-Feng Yang, Wen Ouyang, Bruce Pitt, Timothy Billiar, Li-Ming Zhang

Int J Mol Med. 2019 Mar; 43(3): 1217–1228. Published online 2019 Jan 17. doi: 10.3892/ijmm.2019.4067

PMCID:: PMC6365043

Abstract Article PDF–1.7M

Select item 52199173.

Differential Expression of Ccn4 and Other Genes Between Metastatic and Non-metastatic EL4 Mouse Lymphoma Cells

MANPREET S. CHAHAL, H. TERESA KU, ZHIHONG ZHANG, CHRISTIAN M. LEGASPI, ANGELA LUO, MANDI M. HOPKINS, KATHRYN E. MEIER

Cancer Genomics Proteomics. 2016 Nov-Dec; 13(6): 437–442. Published online 2016 Oct 18. doi: 10.21873/cgp.20006

PMCID:: PMC5219917

Abstract Article PDF–186K

Select item 34886254.

WNT1-Inducible Signaling Pathway Protein 1 Contributes to Ventilator-Induced Lung Injury

Hui-Hua Li, Quan Li, Pengyuan Liu, Yulin Liu, Jin Li, Karla Wasserloos, Wei Chao, Ming You, Tim D. Oury, Sodhi Chhinder, David J. Hackam, Timothy R. Billiar, George D. Leikauf, Bruce R. Pitt, Li-Ming Zhang

Am J Respir Cell Mol Biol. 2012 Oct; 47(4): 528–535. doi: 10.1165/rcmb.2012-0127OC

PMCID:: PMC3488625

Abstract Article PDF–1.1M

Select item 22121225.

Expression of the Elm1 Gene, a Novel Gene of the CCN (Connective Tissue Growth Factor, Cyr61/Cef10, and Neuroblastoma Overexpressed Gene) Family, Suppresses In Vivo Tumor Growth and Metastasis of K-1735 Murine Melanoma Cells

Yasunobu Hashimoto, Nobuko Shindo-Okada, Masachika Tani, Yasuhiro Nagamachi, Kaori Takeuchi, Toshihiko Shiroishi, Hiroshi Toma, Jun Yokota

J Exp Med. 1998 Feb 2; 187(3): 289–296. doi: 10.1084/jem.187.3.289

PMCID:: PMC2212122

Abstract Article PDF–277K

Select item 111720926.

WISP-1 Regulates Cardiac Fibrosis by Promoting Cardiac Fibroblasts’ Activation and Collagen Processing

Ze Li, Helen Williams, Molly L. Jackson, Jason L. Johnson, Sarah J. George

Cells. 2024 Jun; 13(11): 989. Published online 2024 Jun 6. doi: 10.3390/cells13110989

PMCID:: PMC11172092

Abstract Article PDF–6.8M

Select item 98680767.

HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

Lisa C Green, Samuel Slone, Sarah R Anthony, Adrienne R Guarnieri, Sharon Parkins, Shannon M Shearer, Michelle L Nieman, Sudeshna Roy, Jeffrey Aube, Xiaoqing Wu, Liang Xu, Onur Kanisicak, Michael Tranter

J Mol Cell Cardiol. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: J Mol Cell Cardiol. 2023 Jan; 174: 38–46. Published online 2022 Nov 11. doi: 10.1016/j.yjmcc.2022.10.007

PMCID:: PMC9868076

Abstract Article PDF–1.3M

Select item 84797018.

Mechanical stimulations can inhibit local and remote tumor progression by downregulating WISP1

Shengzhi Liu, Di Wu, Xun Sun, Yao Fan, Rongrong Zha, Aydin Jalali, Meghana Teli, Tomonori Sano, Amanda Siegel, Akihiro Sudo, Mangilal Agarwal, Alexander Robling, Bai-Yan Li, Hiroki Yokota

FASEB J. Author manuscript; available in PMC 2021 Sep 29.

Published in final edited form as: FASEB J. 2020 Sep; 34(9): 12847–12859. Published online 2020 Aug 3. doi: 10.1096/fj.202000713RR

PMCID:: PMC8479701

Abstract Article PDF–1.5M

Select item 76894689.

Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells

Rebeca Fernandez-Ruiz, Ainhoa García-Alamán, Yaiza Esteban, Joan Mir-Coll, Berta Serra-Navarro, Marta Fontcuberta-PiSunyer, Christophe Broca, Mathieu Armanet, Anne Wojtusciszyn, Vardit Kram, Marian F. Young, Josep Vidal, Ramon Gomis, Rosa Gasa

Nat Commun. 2020; 11: 5982. Published online 2020 Nov 25. doi: 10.1038/s41467-020-19657-1

PMCID:: PMC7689468

Abstract Article PDF–5.6M

Select item 740625510.

Endogenous CCN family member WISP1 inhibits trauma-induced heterotopic ossification

Ginny Ching-Yun Hsu, Simone Marini, Stefano Negri, Yiyun Wang, Jiajia Xu, Chase Pagani, Charles Hwang, David Stepien, Carolyn A. Meyers, Sarah Miller, Edward McCarthy, Karen M. Lyons, Benjamin Levi, Aaron W. James

JCI Insight. 2020 Jul 9; 5(13): e135432. Published online 2020 Jul 9. doi: 10.1172/jci.insight.135432

PMCID:: PMC7406255

Abstract Article PDF–20M

Select item 640823011.

Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors

Laura Lukjanenko, Sonia Karaz, Pascal Stuelsatz, Uxia Gurriaran-Rodriguez, Joris Michaud, Gabriele Dammone, Federico Sizzano, Omid Mashinchian, Sara Ancel, Eugenia Migliavacca, Sophie Liot, Guillaume Jacot, Sylviane Metairon, Frederic Raymond, Patrick Descombes, Alessio Palini, Benedicte Chazaud, Michael A. Rudnicki, C. Florian Bentzinger, Jerome N. Feige

Cell Stem Cell. Author manuscript; available in PMC 2020 Mar 7.

Published in final edited form as: Cell Stem Cell. 2019 Mar 7; 24(3): 433–446.e7. Published online 2019 Jan 24. doi: 10.1016/j.stem.2018.12.014

PMCID:: PMC6408230

Abstract Article PDF–1.2M

Select item 608546412.

Tp53 Mutation Inhibits Ubiquitination and Degradation of WISP1 via Down-Regulation of Siah1 in Pancreatic Carcinogenesis

Wei Wu, Xu Liu, Lumin Wei, Tong Li, Yi Zang, Yuting Qian, Tingting Bai, Juanjuan Li, Mingping Xie, Ying Zhu, Qi Wang, Lifu Wang

Front Pharmacol. 2018; 9: 857. Published online 2018 Aug 3. doi: 10.3389/fphar.2018.00857

PMCID:: PMC6085464

Abstract Article PDF–3.6M

Select item 534671213.

Notch1—WISP-1 axis determines the regulatory role of mesenchymal stem cell-derived stromal fibroblasts in melanoma metastasis

Hongwei Shao, Long Cai, Mecker Moller, Biju Issac, Leiming Zhang, Mark Owyong, Anna Elizabeth Moscowitz, Roberto Vazquez-Padron, Freddy Radtke, Zhao-Jun Liu

Oncotarget. 2016 Nov 29; 7(48): 79262–79273. Published online 2016 Nov 2. doi: 10.18632/oncotarget.13021

PMCID:: PMC5346712

Abstract Article PDF–4.3M

Select item 473176714.

WISP1 mediates hepatic warm ischemia reperfusion injury via TLR4 signaling in mice

Yao Tong, Xi-Bing Ding, Zhi-Xia Chen, Shu-Qing Jin, Xiang Zhao, Xin Wang, Shu-Ya Mei, Xi Jiang, Lingyu Wang, Quan Li

Sci Rep. 2016; 6: 20141. Published online 2016 Jan 29. doi: 10.1038/srep20141

PMCID:: PMC4731767

Abstract Article PDF–1.6M

Select item 444797315.

WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling

Azusa Maeda, Mitsuaki Ono, Kenn Holmbeck, Li Li, Tina M. Kilts, Vardit Kram, Megan L. Noonan, Yuya Yoshioka, Erin M. B. McNerny, Margaret A. Tantillo, David H. Kohn, Karen M. Lyons, Pamela G. Robey, Marian F. Young

J Biol Chem. 2015 May 29; 290(22): 14004–14018. Published online 2015 Apr 11. doi: 10.1074/jbc.M114.628818

PMCID:: PMC4447973

Abstract Article PDF–5.5M

Select item 342813116.

A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model

Yogesh M. Kulkarni, Emily Chambers, A. J. Robert McGray, Jason S. Ware, Jonathan L. Bramson, David J. Klinke, II

Integr Biol (Camb) Author manuscript; available in PMC 2013 Aug 23.

Published in final edited form as: Integr Biol (Camb). 2012 Aug 23; 4(8): 925–936. Published online 2012 Jul 9. doi: 10.1039/c2ib20053h

PMCID:: PMC3428131

Abstract Article PDF–3.5M

Select item 266254017.

WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

Melanie Königshoff, Monika Kramer, Nisha Balsara, Jochen Wilhelm, Oana Veronica Amarie, Andreas Jahn, Frank Rose, Ludger Fink, Werner Seeger, Liliana Schaefer, Andreas Günther, Oliver Eickelberg

J Clin Invest. 2009 Apr 1; 119(4): 772–787. Published online 2009 Mar 16. doi: 10.1172/JCI33950