PMC Links for Gene (Select 2237) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 210

<< First< Prev

Page of 11

Next >Last >>

Select item 108893471.

FEN1 Inhibition as a Potential Novel Targeted Therapy against Breast Cancer and the Prognostic Relevance of FEN1

Johanna Berfelde, Laura S. Hildebrand, Lukas Kuhlmann, Rainer Fietkau, Luitpold V. Distel

Int J Mol Sci. 2024 Feb; 25(4): 2110. Published online 2024 Feb 9. doi: 10.3390/ijms25042110

PMCID:: PMC10889347

Abstract Article PDF–6.0M

Select item 96665352.

Mechanistic investigation of human maturation of Okazaki fragments reveals slow kinetics

Vlad-Stefan Raducanu, Muhammad Tehseen, Amani Al-Amodi, Luay I. Joudeh, Alfredo De Biasio, Samir M. Hamdan

Nat Commun. 2022; 13: 6973. Published online 2022 Nov 15. doi: 10.1038/s41467-022-34751-2

PMCID:: PMC9666535

Abstract Article PDF–5.6M

Select item 82332933.

The prognostic significance of Flap Endonuclease 1 (FEN1) in breast ductal carcinoma in situ

Abdulbaqi Al-Kawaz, Islam M. Miligy, Michael S. Toss, Omar J. Mohammed, Andrew R. Green, Srinivasan Madhusudan, Emad A. Rakha

Breast Cancer Res Treat. 2021; 188(1): 53–63. Published online 2021 Jun 12. doi: 10.1007/s10549-021-06271-y

PMCID:: PMC8233293

Abstract Article PDF–1022K

Select item 81063094.

Setting molecular traps in yeast for identification of anticancer drug targets

Grant W. Brown, Brenda Andrews

Proc Natl Acad Sci U S A. 2021 May 4; 118(18): e2105547118. Published online 2021 Apr 14. doi: 10.1073/pnas.2105547118

PMCID:: PMC8106309

Article PDF–552K

Select item 76103275.

Biological and clinical significance of flap endonuclease-1 in triple-negative breast cancer: Support of metastasis and a poor prognosis

Lu Xu, Jing-Lei Qu, Na Song, Ling-Yun Zhang, Xue Zeng, Xiao-Fang Che, Ke-Zuo Hou, Sha Shi, Zu-Ying Feng, Xiu-Juan Qu, Yun-Peng Liu, Yue-E Teng

Oncol Rep. 2020 Dec; 44(6): 2443–2454. Published online 2020 Oct 16. doi: 10.3892/or.2020.7812

PMCID:: PMC7610327

Abstract Article PDF–2.6M

Select item 74310966.

FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination

Elaine Guo, Yuki Ishii, James Mueller, Anjana Srivatsan, Timothy Gahman, Christopher D. Putnam, Jean Y. J. Wang, Richard D. Kolodner

Proc Natl Acad Sci U S A. 2020 Aug 11; 117(32): 19415–19424. Published online 2020 Jul 27. doi: 10.1073/pnas.2009237117

PMCID:: PMC7431096

Abstract Article PDF–1.2M

Select item 72014457.

Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma

Yingying Zhang, Xin Liu, Liwen Liu, Jianan Chen, Qiuyue Hu, Shen Shen, Yongjian Zhou, Siyu Chen, Chen Xue, Guangying Cui, Zujiang Yu

Dis Markers. 2020; 2020: 2514090. Published online 2020 Jan 13. doi: 10.1155/2020/2514090

PMCID:: PMC7201445

Abstract Article PDF–3.1M

Select item 69696508.

Artichoke Polyphenols Sensitize Human Breast Cancer Cells to Chemotherapeutic Drugs via a ROS-Mediated Downregulation of Flap Endonuclease 1

Anna Maria Mileo, Donato Di Venere, Stefania Mardente, Stefania Miccadei

Oxid Med Cell Longev. 2020; 2020: 7965435. Published online 2020 Jan 3. doi: 10.1155/2020/7965435

PMCID:: PMC6969650

Abstract Article PDF–1.4M

Select item 62654649.

Structural basis of 5′ flap recognition and protein–protein interactions of human flap endonuclease 1

Hong Xu, Rongyi Shi, Wanchun Han, Jiahui Cheng, Xiaoli Xu, Kaiying Cheng, Liangyan Wang, Bing Tian, Li Zheng, Binghui Shen, Yuejin Hua, Ye Zhao

Nucleic Acids Res. 2018 Nov 30; 46(21): 11315–11325. Published online 2018 Oct 8. doi: 10.1093/nar/gky911

PMCID:: PMC6265464

Abstract Article PDF–7.0M

Select item 612568310.

A conserved loop–wedge motif moderates reaction site search and recognition by FEN1

Mark J Thompson, Victoria J B Gotham, Barbara Ciani, Jane A Grasby

Nucleic Acids Res. 2018 Sep 6; 46(15): 7858–7872. Published online 2018 Jun 7. doi: 10.1093/nar/gky506

PMCID:: PMC6125683

Abstract Article PDF–6.7M

Select item 607032811.

The Association of Flap Endonuclease 1 Genotypes with the Susceptibility of Endometriosis

AN-KUO CHOU, MING-YI SHEN, FANG-YU CHEN, CHIEH-LUN HSIAO, LIANG-CHUN SHIH, WEN-SHIN CHANG, CHIA-WEN TSAI, TSUNG-HO YING, MING-HSIEN WU, CHUNG-YU HUANG, DA-TIAN BAU

Cancer Genomics Proteomics. 2017 Nov-Dec; 14(6): 455–460. Published online 2017 Nov 3. doi: 10.21873/cgp.20055

PMCID:: PMC6070328

Abstract Article PDF–106K

Select item 600964612.

Regional conformational flexibility couples substrate specificity and scissile phosphate diester selectivity in human flap endonuclease 1

Ian A Bennet, L David Finger, Nicola J Baxter, Benjamin Ambrose, Andrea M Hounslow, Mark J Thompson, Jack C Exell, Nur Nazihah B Md Shahari, Timothy D Craggs, Jonathan P Waltho, Jane A Grasby

Nucleic Acids Res. 2018 Jun 20; 46(11): 5618–5633. Published online 2018 Apr 30. doi: 10.1093/nar/gky293

PMCID:: PMC6009646

Abstract Article PDF–3.5M

Select item 588012313.

Positioning the 5′-flap junction in the active site controls the rate of flap endonuclease-1–catalyzed DNA cleavage

Bo Song, Samir M. Hamdan, Manju M. Hingorani

J Biol Chem. 2018 Mar 30; 293(13): 4792–4804. Published online 2018 Feb 9. doi: 10.1074/jbc.RA117.001137

PMCID:: PMC5880123

Abstract Article PDF–2.1M

Select item 574552914.

Overexpression of Flap Endonuclease 1 Correlates with Enhanced Proliferation and Poor Prognosis of Non–Small-Cell Lung Cancer

Keqiang Zhang, Sawa Keymeulen, Rebecca Nelson, Tommy R. Tong, Yate-Ching Yuan, Xinwei Yun, Zheng Liu, Joshua Lopez, Dan J. Raz, Jae Y. Kim

Am J Pathol. 2018 Jan; 188(1): 242–251. doi: 10.1016/j.ajpath.2017.09.011

PMCID:: PMC5745529

Abstract Article PDF–2.9M

Select item 549027115.

Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability

Susan E. Tsutakawa, Mark J. Thompson, Andrew S. Arvai, Alexander J. Neil, Steven J. Shaw, Sana I. Algasaier, Jane C. Kim, L. David Finger, Emma Jardine, Victoria J.B. Gotham, Altaf H. Sarker, Mai Z. Her, Fahad Rashid, Samir M. Hamdan, Sergei M. Mirkin, Jane A. Grasby, John A. Tainer

Nat Commun. 2017; 8: 15855. Published online 2017 Jun 27. doi: 10.1038/ncomms15855

Correction in:: Nat Commun. 2017; 8: 16145.

PMCID:: PMC5490271

Abstract Article PDF–3.1M

Select item 546749716.

FEN1 promotes tumor progression and confers cisplatin resistance in non‐small‐cell lung cancer

Lingfeng He, Libo Luo, Hong Zhu, Huan Yang, Yilan Zhang, Huan Wu, Hongfang Sun, Feng Jiang, Chandra S. Kathera, Lingjie Liu, Ziheng Zhuang, Haoyan Chen, Feiyan Pan, Zhigang Hu, Jing Zhang, Zhigang Guo

Mol Oncol. 2017 Jun; 11(6): 640–654. Published online 2017 May 12. doi: 10.1002/1878-0261.12058

Correction in:: Mol Oncol. 2017 Sep; 11(9): 1302–1303.

PMCID:: PMC5467497

Abstract Article PDF–1.0M

Select item 541546517.

Flap endonuclease‐1 rs174538 G>A polymorphisms are associated with the risk of esophageal cancer in a Chinese population

Yonghua Sang, Lin Bo, Haiyong Gu, Wengtao Yang, Yongbing Chen

Thorac Cancer. 2017 May; 8(3): 192–196. Published online 2017 Mar 20. doi: 10.1111/1759-7714.12422

PMCID:: PMC5415465

Abstract Article PDF–123K

Select item 536364718.

FEN1 gene variants confer reduced risk of breast cancer in chinese women: A case-control study

Shuai Lin, Meng Wang, Xinghan Liu, Ye Lu, Zhuoqing Gong, Yan Guo, Pengtao Yang, Tian Tian, Cong Dai, Yi Zheng, Peng Xu, Shanli Li, Yuyao Zhu, Zhijun Dai

Oncotarget. 2016 Nov 22; 7(47): 78110–78118. Published online 2016 Oct 27. doi: 10.18632/oncotarget.12948

PMCID:: PMC5363647

Abstract Article PDF–1.6M

Select item 535897919.

Single-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1

Fahad Rashid, Paul D Harris, Manal S Zaher, Mohamed A Sobhy, Luay I Joudeh, Chunli Yan, Hubert Piwonski, Susan E Tsutakawa, Ivaylo Ivanov, John A Tainer, Satoshi Habuchi, Samir M Hamdan

eLife. 2017; 6: e21884. Published online 2017 Feb 23. doi: 10.7554/eLife.21884

PMCID:: PMC5358979

Abstract Article PDF–2.6M

Select item 514077520.

The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation

H Sun, L He, H Wu, F Pan, X Wu, J Zhao, Z Hu, C Sekhar, H Li, L Zheng, H Chen, B H Shen, Z Guo

Oncogene. 2017 Jan 12; 36(2): 194–207. Published online 2016 Jun 6. doi: 10.1038/onc.2016.188

PMCID:: PMC5140775

Abstract Article PDF–2.4M

<< First< Prev

Page of 11

Next >Last >>

Supplemental Content

Filter your results:

Manage Filters

Find related data

Recent activity

Clear Turn Off Turn On

PMC Links for Gene (Select 2237) (210)
PMC
Russula nigricans clone JW47.1 18S ribosomal RNA gene, partial sequence; interna...
Russula nigricans clone JW47.1 18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence
gi|529273180|gb|KC952713.1|

Nucleotide

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to: