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Select item 100541651.

The role of cyclin Y in normal and pathological cells

Aleksandra Opacka, Agnieszka Żuryń, Adrian Krajewski, Klaudia Mikołajczyk

Cell Cycle. 2023; 22(8): 859–869. Published online 2022 Dec 28. doi: 10.1080/15384101.2022.2162668

PMCID:: PMC10054165

Abstract Article PDF–736K

Select item 76622342.

Cyclin Y Is Expressed in Platelets and Modulates Integrin Outside-in Signaling

Anastasia Kyselova, Mauro Siragusa, Julian Anthes, Fiorella Andrea Solari, Stefan Loroch, René P. Zahedi, Ulrich Walter, Ingrid Fleming, Voahanginirina Randriamboavonjy

Int J Mol Sci. 2020 Nov; 21(21): 8239. Published online 2020 Nov 3. doi: 10.3390/ijms21218239

PMCID:: PMC7662234

Abstract Article PDF–2.2M

Select item 58733313.

Cyclin Y Modulates the Proliferation, Invasion, and Metastasis of Hepatocellular Carcinoma Cells

Kaishun Shi, Qingjing Ru, Chenyi Zhang, Jie Huang

Med Sci Monit. 2018; 24: 1642–1653. Published online 2018 Mar 20. doi: 10.12659/MSM.906075

PMCID:: PMC5873331

Abstract Article PDF–2.3M

Select item 34958194.

Orphan kinases turn eccentric: A new class of cyclin Y-activated, membrane-targeted CDKs

Petra Mikolcevic, Johannes Rainer, Stephan Geley

Cell Cycle. 2012 Oct 15; 11(20): 3758–3768. doi: 10.4161/cc.21592

PMCID:: PMC3495819

Abstract Article PDF–4.7M

Select item 70423295.

AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

Marc Dohmen, Sarah Krieg, Georgios Agalaridis, Xiaoqing Zhu, Saifeldin N. Shehata, Elisabeth Pfeiffenberger, Jan Amelang, Mareike Bütepage, Elena Buerova, Carolina M. Pfaff, Dipanjan Chanda, Stephan Geley, Christian Preisinger, Kei Sakamoto, Bernhard Lüscher, Dietbert Neumann, Jörg Vervoorts

Nat Commun. 2020; 11: 1032. Published online 2020 Feb 25. doi: 10.1038/s41467-020-14812-0

PMCID:: PMC7042329

Abstract Article PDF–2.9M

Select item 63491786.

Fisetin decreases TET1 activity and CCNY/CDK16 promoter 5hmC levels to inhibit the proliferation and invasion of renal cancer stem cell

Yibing Si, Junfeng Liu, Hongliang Shen, Chen Zhang, Yuanhao Wu, Yongyi Huang, Zhangbin Gong, Jun Xue, Te Liu

J Cell Mol Med. 2019 Feb; 23(2): 1095–1105. Published online 2018 Nov 8. doi: 10.1111/jcmm.14010

PMCID:: PMC6349178

Abstract Article PDF–1.4M

Select item 55374147.

The genomic dynamics during progression of lung adenocarcinomas

Bin Yang, Longhai Luo, Wen Luo, Yong Zhou, Chao Yang, Teng Xiong, Xiangchun Li, Xuan Meng, Lin Li, Xiaopin Zhang, Zhe Wang, Zhixin Wang

J Hum Genet. 2017 Aug; 62(8): 783–788. Published online 2017 Apr 6. doi: 10.1038/jhg.2017.40

PMCID:: PMC5537414

Abstract Article PDF–575K

Select item 46135158.

Cyclin Y phosphorylation- and 14-3-3-binding-dependent activation of PCTAIRE-1/CDK16

Saifeldin N. Shehata, Maria Deak, Nicholas A. Morrice, Eriko Ohta, Roger W. Hunter, Vera M. Kalscheuer, Kei Sakamoto

Biochem J. 2015 Aug 1; 469(Pt 3): 409–420. Prepublished online 2015 Jun 10. Published online 2015 Jul 23. doi: 10.1042/BJ20150486

PMCID:: PMC4613515

Abstract Article PDF–1.1M

Select item 51595039.

Activation/Proliferation-associated Protein 2 (Caprin-2) Positively Regulates CDK14/Cyclin Y-mediated Lipoprotein Receptor-related Protein 5 and 6 (LRP5/6) Constitutive Phosphorylation

Xin Wang, Yingying Jia, Cong Fei, Xiaomin Song, Lin Li

J Biol Chem. 2016 Dec 16; 291(51): 26427–26434. Published online 2016 Nov 7. doi: 10.1074/jbc.M116.744607

PMCID:: PMC5159503

Abstract Article PDF–1.1M

Select item 327297310.

Cyclin-Dependent Kinase 16/PCTAIRE Kinase 1 Is Activated by Cyclin Y and Is Essential for Spermatogenesis

Petra Mikolcevic, Reinhard Sigl, Veronika Rauch, Michael W. Hess, Kristian Pfaller, Marin Barisic, Lauri J. Pelliniemi, Michael Boesl, Stephan Geley

Mol Cell Biol. 2012 Feb; 32(4): 868–879. doi: 10.1128/MCB.06261-11

PMCID:: PMC3272973

Abstract Article PDF–2.9M

Select item 286089411.

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

Kai Wang, Robert Baldassano, Haitao Zhang, Hui-Qi Qu, Marcin Imielinski, Subra Kugathasan, Vito Annese, Marla Dubinsky, Jerome I. Rotter, Richard K. Russell, Jonathan P. Bradfield, Patrick M.A. Sleiman, Joseph T. Glessner, Thomas Walters, Cuiping Hou, Cecilia Kim, Edward C. Frackelton, Maria Garris, James Doran, Claudio Romano, Carlo Catassi, Johan Van Limbergen, Stephen L. Guthery, Lee Denson, David Piccoli, Mark S. Silverberg, Charles A. Stanley, Dimitri Monos, David C. Wilson, Anne Griffiths, Struan F.A. Grant, Jack Satsangi, Constantin Polychronakos, Hakon Hakonarson

Hum Mol Genet. 2010 May 15; 19(10): 2059–2067. Published online 2010 Feb 22. doi: 10.1093/hmg/ddq078

PMCID:: PMC2860894

Abstract Article PDF–166K

Select item 263692612.

KIF5B gene sequence variation and response of cardiac stroke volume to regular exercise

George Argyropoulos, Adrian M. Stütz, Olha Ilnytska, Treva Rice, Margarita Teran-Garcia, D. C. Rao, Claude Bouchard, Tuomo Rankinen

Physiol Genomics. 2009 Jan; 36(2): 79–88. Published online 2008 Nov 4. doi: 10.1152/physiolgenomics.00003.2008

PMCID:: PMC2636926

Abstract Article

Select item 267513713.

Investigation of Crohn’s Disease Risk Loci in Ulcerative Colitis Further Defines Their Molecular Relationship

CARL A. ANDERSON, DUNECAN C. O. MASSEY, JEFFREY C. BARRETT, NATALIE J. PRESCOTT, MARK TREMELLING, SHEILA A. FISHER, RHIAN GWILLIAM, JEMIMA JACOB, ELAINE R. NIMMO, HAZEL DRUMMOND, CHARLIE W. LEES, CLIVE M. ONNIE, CATHERINE HANSON, KATARZYNA BLASZCZYK, RADHI RAVINDRARAJAH, SARAH HUNT, DHIRAJ VARMA, NAOMI HAMMOND, GREGORY LEWIS, HEATHER ATTLESEY, NICK WATKINS, WILLEM OUWEHAND, DAVID STRACHAN, WENDY MCARDLE, CATHRYN M. LEWIS, The Wellcome Trust Case Control Consortium, ALAN LOBO, JEREMY SANDERSON, DEREK P. JEWELL, PANOS DELOUKAS, JOHN C. MANSFIELD, CHRISTOPHER G. MATHEW, JACK SATSANGI, MILES PARKES

Gastroenterology. Author manuscript; available in PMC 2009 Aug 1.

Published in final edited form as: Gastroenterology. 2009 Feb; 136(2): 523–9.e3. Published online 2008 Oct 25. doi: 10.1053/j.gastro.2008.10.032

PMCID:: PMC2675137

Abstract Article PDF–291K

Select item 294484614.

Molecular Reclassification of Crohn's Disease by Cluster Analysis of Genetic Variants

Isabelle Cleynen, Jestinah M. Mahachie John, Liesbet Henckaerts, Wouter Van Moerkercke, Paul Rutgeerts, Kristel Van Steen, Severine Vermeire

PLoS One. 2010; 5(9): e12952. Published online 2010 Sep 23. doi: 10.1371/journal.pone.0012952

PMCID:: PMC2944846

Abstract Article PDF–553K

Select item 308459715.

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Carl A. Anderson, Gabrielle Boucher, Charlie W. Lees, Andre Franke, Mauro D’Amato, Kent D. Taylor, James C. Lee, Philippe Goyette, Marcin Imielinski, Anna Latiano, Caroline Lagacé, Regan Scott, Leila Amininejad, Suzannah Bumpstead, Leonard Baidoo, Robert N. Baldassano, Murray Barclay, Theodore M. Bayless, Stephan Brand, Carsten Büning, Jean-Frédéric Colombel, Lee A. Denson, Martine De Vos, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Rudolf S.N. Fehrmann, James A.B. Floyd, Tim Florin, Denis Franchimont, Lude Franke, Michel Georges, Jürgen Glas, Nicole L. Glazer, Stephen L. Guthery, Talin Haritunians, Nicholas K. Hayward, Jean-Pierre Hugot, Gilles Jobin, Debby Laukens, Ian Lawrance, Marc Lémann, Arie Levine, Cecile Libioulle, Edouard Louis, Dermot P. McGovern, Monica Milla, Grant W. Montgomery, Katherine I. Morley, Craig Mowat, Aylwin Ng, William Newman, Roel A Ophoff, Laura Papi, Orazio Palmieri, Laurent Peyrin-Biroulet, Julián Panés, Anne Phillips, Natalie J. Prescott, Deborah D. Proctor, Rebecca Roberts, Richard Russell, Paul Rutgeerts, Jeremy Sanderson, Miquel Sans, Philip Schumm, Frank Seibold, Yashoda Sharma, Lisa Simms, Mark Seielstad, A. Hillary Steinhart, Stephan R. Targan, Leonard H. van den Berg, Morten Vatn, Hein Verspaget, Thomas Walters, Cisca Wijmenga, David C. Wilson, Harm-Jan Westra, Ramnik J. Xavier, Zhen Z. Zhao, Cyriel Y. Ponsioen, Vibeke Andersen, Leif Torkvist, Maria Gazouli, Nicholas P. Anagnou, Tom H. Karlsen, Limas Kupcinskas, Jurgita Sventoraityte, John C. Mansfield, Subra Kugathasan, Mark S. Silverberg, Jonas Halfvarson, Jerome I. Rotter, Christopher G. Mathew, Anne M. Griffiths, Richard Gearry, Tariq Ahmad, Steven R. Brant, Mathias Chamaillard, Jack Satsangi, Judy H. Cho, Stefan Schreiber, Mark J. Daly, Jeffrey C. Barrett, Miles Parkes, Vito Annese, Hakon Hakonarson, Graham Radford-Smith, Richard H. Duerr, Séverine Vermeire, Rinse K. Weersma, John D. Rioux

Nat Genet. Author manuscript; available in PMC 2011 Sep 1.

Published in final edited form as: Nat Genet. 2011 Mar; 43(3): 246–252. Published online 2011 Feb 6. doi: 10.1038/ng.764

Correction in:: volume 43 on page 919

PMCID:: PMC3084597

Abstract Article PDF–404K

Select item 286078316.

Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer’s disease

J Chapuis, D Hot, F Hansmannel, O Kerdraon, S Ferreira, C Hubans, CA Maurage, L Huot, F Bensemain, G Laumet, AM Ayral, N Fievet, JJ Hauw, ST DeKosky, Y Lemoine, T Iwatsubo, F Wavrant-Devrièze, JF Dartigues, C Tzourio, L Buée, F Pasquier, C Berr, D Mann, C Lendon, A Alpérovitch, MI Kamboh, P Amouyel, JC Lambert

Mol Psychiatry. Author manuscript; available in PMC 2010 Apr 28.

Published in final edited form as: Mol Psychiatry. 2009 Nov; 14(11): 1004–1016. Published online 2009 Feb 10. doi: 10.1038/mp.2009.10

PMCID:: PMC2860783

Abstract Article PDF–1.3M

Select item 329955117.

Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci

Andre Franke, Dermot P.B. McGovern, Jeffrey C. Barrett, Kai Wang, Graham L. Radford-Smith, Tariq Ahmad, Charlie W. Lees, Tobias Balschun, James Lee, Rebecca Roberts, Carl A. Anderson, Joshua C. Bis, Suzanne Bumpstead, David Ellinghaus, Eleonora M. Festen, Michel Georges, Talin Haritunians, Luke Jostins, Anna Latiano, Christopher G. Mathew, Grant W. Montgomery, Natalie J. Prescott, Jerome I. Rotter, Philip Schumm, Yashoda Sharma, Lisa A. Simms, Kent D. Taylor, David Whiteman, Cisca Wijmenga, Robert N. Baldassano, Murray Barclay, Theodore M. Bayless, Stephan Brand, Carsten Buning, Albert Cohen, Jean-Frederick Colombel, Mario Cottone, Laura Stronati, Ted Denson, Martine De Vos, Renata D’Inca, Marla Dubinsky, Cathryn Edwards, Tim Florin, Denis Franchimont, Richard Gearry, Jürgen Glas, Andre Van Gossum, Stephen L. Guthery, Jonas Halfvarson, Daan Hommes, Jean-Pierre Hugot, Debby Laukens, Ian Lawrance, Marc Lemann, Arie Levine, Cecile Libioulle, Edouard Louis, Craig Mowat, William Newman, Julián Panés, Anne Phillips, Deborah D. Proctor, Miguel Regueiro, Paul Rutgeerts, Jeremy Sanderson, Miquel Sans, Frank Seibold, A. Hillary Steinhart, Pieter C.F. Stokkers, Leif Torkvist, Gerd Kullak Ublick, Soumya Raychaudhuri, Todd Green, Thomas Walters, Stephan R. Targan, Steven R. Brant, John D. Rioux, Mauro D’Amato, Rinse Weersma, Subra Kugathasan, Anne M. Griffiths, John C. Mansfield, Severine Vermeire, Richard H. Duerr, Mark S. Silverberg, Jack Satsangi, Stefan Schreiber, Judy H. Cho, Vito Annese, Hakon Hakonarson, Mark J. Daly, Miles Parkes

Nat Genet. Author manuscript; available in PMC 2012 Mar 12.

Published in final edited form as: Nat Genet. 2010 Dec; 42(12): 1118–1125. doi: 10.1038/ng.717

PMCID:: PMC3299551

Article PDF–864K

Select item 431995118.

ABCE1 Is a Highly Conserved RNA Silencing Suppressor

Kairi Kärblane, Jelena Gerassimenko, Lenne Nigul, Alla Piirsoo, Agata Smialowska, Kadri Vinkel, Per Kylsten, Karl Ekwall, Peter Swoboda, Erkki Truve, Cecilia Sarmiento

PLoS One. 2015; 10(2): e0116702. Published online 2015 Feb 6. doi: 10.1371/journal.pone.0116702

PMCID:: PMC4319951

Abstract Article PDF–2.8M

Select item 962912119.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 138022520.

A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease

Andrew Grupe, Yonghong Li, Charles Rowland, Petra Nowotny, Anthony L. Hinrichs, Scott Smemo, John S. K. Kauwe, Taylor J. Maxwell, Sara Cherny, Lisa Doil, Kristina Tacey, Ryan van Luchene, Amanda Myers, Fabienne Wavrant-De Vrièze, Mona Kaleem, Paul Hollingworth, Luke Jehu, Catherine Foy, Nicola Archer, Gillian Hamilton, Peter Holmans, Chris M. Morris, Joseph Catanese, John Sninsky, Thomas J. White, John Powell, John Hardy, Michael O’Donovan, Simon Lovestone, Lesley Jones, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate

Am J Hum Genet. 2006 Jan; 78(1): 78–88. Published online 2005 Nov 15. doi: 10.1086/498851

PMCID:: PMC1380225

Abstract Article PDF–329K

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