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Select item 112277051.

Rankl genetic deficiency and functional blockade undermine skeletal stem and progenitor cell differentiation

M. L. Schiavone, L. Crisafulli, C. Camisaschi, G. De Simone, F. R. Liberati, E. Palagano, N. Rucci, F. Ficara, Cristina Sobacchi

Stem Cell Res Ther. 2024; 15: 203. Published online 2024 Jul 6. doi: 10.1186/s13287-024-03803-3

PMCID:: PMC11227705

Abstract Article PDF–2.8M

Select item 111408532.

Osteocyte RANKL Drives Bone Resorption in Mouse Ligature‐Induced Periodontitis

Mizuho Kittaka, Tetsuya Yoshimoto, Marcus E Levitan, Rina Urata, Roy B Choi, Yayoi Teno, Yixia Xie, Yukiko Kitase, Matthew Prideaux, Sarah L Dallas, Alexander G Robling, Yasuyoshi Ueki

J Bone Miner Res. 2023 Oct 1; 38(10): 1521–1540. Published online 2023 Oct 1. doi: 10.1002/jbmr.4897

PMCID:: PMC11140853

Abstract Article PDF–4.2M

Select item 104174153.

Α Humanized RANKL Transgenic Mouse Model of Progestin-Induced Mammary Carcinogenesis for Evaluation of Novel Therapeutics

Anthi Kolokotroni, Evi Gkikopoulou, Vagelis Rinotas, Lydia Ntari, Danae Zareifi, Maritina Rouchota, Sophia Sarpaki, Ilias Lymperopoulos, Leonidas G. Alexopoulos, George Loudos, Maria C. Denis, Niki Karagianni, Eleni Douni

Cancers (Basel) 2023 Aug; 15(15): 4006. Published online 2023 Aug 7. doi: 10.3390/cancers15154006

PMCID:: PMC10417415

Abstract Article PDF–3.9M

Select item 102558304.

Histopathologic and Transcriptomic Phenotypes of a Conditional RANKL Transgenic Mouse Thymus

Maria M. Szwarc, Lan Hai, Vineet K. Maurya, Kimal Rajapakshe, Dimuthu Perera, Michael M. Ittmann, Qianxing Mo, Yong Lin, Matthew L. Bettini, Cristian Coarfa, John P. Lydon

Cytokine. Author manuscript; available in PMC 2023 Jun 9.

Published in final edited form as: Cytokine. 2022 Dec; 160: 156022. Published online 2022 Sep 11. doi: 10.1016/j.cyto.2022.156022

PMCID:: PMC10255830

Abstract Article PDF–1.9M

Select item 102532255.

RANKL Inhibition Reduces Cardiac Hypertrophy in mdx Mice and Possibly in Children with Duchenne Muscular Dystrophy

Laetitia Marcadet, Emma Sara Juracic, Nasrin Khan, Zineb Bouredji, Hideo Yagita, Leanne M. Ward, A. Russell Tupling, Anteneh Argaw, Jérôme Frenette

Cells. 2023 Jun; 12(11): 1538. Published online 2023 Jun 3. doi: 10.3390/cells12111538

PMCID:: PMC10253225

Abstract Article PDF–4.5M

Select item 102527576.

Role of Mast-Cell-Derived RANKL in Ovariectomy-Induced Bone Loss in Mice

Verena Fischer, Jasmin Maria Bülow, Benjamin Thilo Krüger, Deniz Ragipoglu, Anna Vikman, Melanie Haffner-Luntzer, Konstantinos Katsoulis-Dimitriou, Anne Dudeck, Anita Ignatius

Int J Mol Sci. 2023 Jun; 24(11): 9135. Published online 2023 May 23. doi: 10.3390/ijms24119135

PMCID:: PMC10252757

Abstract Article PDF–6.3M

Select item 93037247.

Excessive osteoclast activation by osteoblast paracrine factor RANKL is a major cause of the abnormal long bone phenotype in Apert syndrome model mice

Hye‐Rim Shin, Bong‐Soo Kim, Hyun‐Jung Kim, Heein Yoon, Woo‐Jin Kim, Je‐Yong Choi, Hyun‐Mo Ryoo

J Cell Physiol. 2022 Apr; 237(4): 2155–2168. Published online 2022 Jan 20. doi: 10.1002/jcp.30682

PMCID:: PMC9303724

Abstract Article PDF–13M

Select item 88770828.

Serial Passaging of RAW 264.7 Cells Modulates Intracellular AGE Formation and Downregulates RANKL-Induced In Vitro Osteoclastogenesis

Tanzima Tarannum Lucy, A. N. M. Mamun-Or-Rashid, Masayuki Yagi, Yoshikazu Yonei

Int J Mol Sci. 2022 Feb; 23(4): 2371. Published online 2022 Feb 21. doi: 10.3390/ijms23042371

PMCID:: PMC8877082

Abstract Article PDF–9.4M

Select item 81097879.

Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo

Ryan S. MacLeod, Mark B. Meyer, Jinhu Xiong, Keisha M. Cawley, Yu Liu, Melda Onal, Nancy A. Benkusky, Jeff D. Thostenson, J. Wesley Pike, Charles A. O’Brien

PLoS One. 2021; 16(5): e0250974. Published online 2021 May 10. doi: 10.1371/journal.pone.0250974

PMCID:: PMC8109787

Abstract Article PDF–1.9M

Select item 800489710.

Inhibitory Effect of LGS and ODE Isolated from the Twigs of Syringa oblata subsp. dilatata on RANKL-Induced Osteoclastogenesis in Macrophage Cells

Ga-Ram Kim, Eun-Nam Kim, Kyoung Jin Park, Ki Hyun Kim, Gil-Saeng Jeong

Molecules. 2021 Mar; 26(6): 1779. Published online 2021 Mar 22. doi: 10.3390/molecules26061779

PMCID:: PMC8004897

Abstract Article PDF–5.1M

Select item 783112211.

In Vitro Macrophage Immunomodulation by Poly(ε-caprolactone) Based-Coated AZ31 Mg Alloy

Andreea-Mariana Negrescu, Madalina-Georgiana Necula, Adi Gebaur, Florentina Golgovici, Cristina Nica, Filis Curti, Horia Iovu, Marieta Costache, Anisoara Cimpean

Int J Mol Sci. 2021 Jan; 22(2): 909. Published online 2021 Jan 18. doi: 10.3390/ijms22020909

PMCID:: PMC7831122

Abstract Article PDF–5.8M

Select item 756670112.

Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence

Ha-Neui Kim, Jinhu Xiong, Ryan S. MacLeod, Srividhya Iyer, Yuko Fujiwara, Keisha M. Cawley, Li Han, Yonghan He, Jeff D. Thostenson, Elisabeth Ferreira, Robert L. Jilka, Daohong Zhou, Maria Almeida, Charles A. O’Brien

JCI Insight. 2020 Oct 2; 5(19): e138815. Published online 2020 Oct 2. doi: 10.1172/jci.insight.138815

PMCID:: PMC7566701

Abstract Article PDF–15M

Select item 752028413.

Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL‐induced osteoclastogenesis

Zhi Qian, Zeyuan Zhong, Shuo Ni, Dejian Li, Fangxue Zhang, Ying Zhou, Zhanrong Kang, Jun Qian, Baoqing Yu

J Cell Mol Med. 2020 Sep; 24(17): 10112–10127. Published online 2020 Aug 13. doi: 10.1111/jcmm.15622

PMCID:: PMC7520284

Abstract Article PDF–2.9M

Select item 744392814.

Short-term RANKL Exposure Initiates a Neoplastic Transcriptional Program in the Basal Epithelium of the Murine Salivary Gland

Lan Hai, Maria M. Szwarc, David M. Lonard, Kimal Rajapakshe, Dimuthu Perera, Cristian Coarfa, Michael Ittmann, Rodrigo Fernandez-Valdivia, John P. Lydon

Cytokine. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Cytokine. 2019 Nov; 123: 154745. Published online 2019 Jun 18. doi: 10.1016/j.cyto.2019.154745

PMCID:: PMC7443928

Abstract Article PDF–2.5M

Select item 743273415.

3-Hydroxyolean-12-en-27-oic Acids Inhibit RANKL-Induced Osteoclastogenesis in Vitro and Inflammation-Induced Bone Loss in Vivo

Wonyoung Seo, Suhyun Lee, Phuong Thao Tran, Thi Quynh-Mai Ngo, Okwha Kim, Thanh Huong Le, Nguyen Hai Dang, Cheol Hwangbo, Byung Sun Min, Jeong-Hyung Lee

Int J Mol Sci. 2020 Aug; 21(15): 5240. Published online 2020 Jul 23. doi: 10.3390/ijms21155240

PMCID:: PMC7432734

Abstract Article PDF–6.3M

Select item 741270116.

Sotrastaurin, a PKC inhibitor, attenuates RANKL‐induced bone resorption and attenuates osteochondral pathologies associated with the development of OA

Cong Pang, Liangbao Wen, Haikuo Qin, Bikang Zhu, Xuanyuan Lu, Shixing Luo

J Cell Mol Med. 2020 Aug; 24(15): 8452–8465. Published online 2020 Jul 11. doi: 10.1111/jcmm.15404

PMCID:: PMC7412701

Abstract Article PDF–2.0M

Select item 723516617.

RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages

Thaís S. Rigoni, Natália S. Vellozo, Mariela Cabral-Piccin, Laryssa Fabiano-Coelho, Ulisses G. Lopes, Alessandra A. Filardy, George A. DosReis, Marcela F. Lopes

Front Immunol. 2020; 11: 886. Published online 2020 May 12. doi: 10.3389/fimmu.2020.00886

PMCID:: PMC7235166

Abstract Article PDF–1.3M

Select item 713932018.

IL-35 and RANKL Synergistically Induce Osteoclastogenesis in RAW264 Mouse Monocytic Cells

Yosuke Kamiya, Takeshi Kikuchi, Hisashi Goto, Iichiro Okabe, Yuhei Takayanagi, Yuki Suzuki, Noritaka Sawada, Teppei Okabe, Yuki Suzuki, Shun Kondo, Jun-ichiro Hayashi, Akio Mitani

Int J Mol Sci. 2020 Mar; 21(6): 2069. Published online 2020 Mar 18. doi: 10.3390/ijms21062069