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Select item 82181091.

Thrombospondin-2 spatiotemporal expression in skeletal fractures

Robert L. Zondervan, Daniel C. Jenkins, John D. Reicha, Kurt D. Hankenson

J Orthop Res. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: J Orthop Res. 2021 Jan; 39(1): 30–41. Published online 2020 May 28. doi: 10.1002/jor.24749

PMCID:: PMC8218109

Abstract Article PDF–7.0M

Select item 46100042.

Thrombospondin-2 deficiency in growing mice alters bone collagen ultrastructure and leads to a brittle bone phenotype

Eugene Manley, Jr, Joseph E. Perosky, Basma M. Khoury, Anita B. Reddy, Kenneth M. Kozloff, Andrea I. Alford

J Appl Physiol (1985) 2015 Oct 15; 119(8): 872–881. Published online 2015 Aug 13. doi: 10.1152/japplphysiol.00340.2015

PMCID:: PMC4610004

Abstract Article

Select item 40916403.

Thrombospondin-2 facilitates assembly of a type I collagen-rich matrix in marrow stromal cells undergoing osteoblastic differentiation

Andrea I. Alford, Andrew Z. Golicz, Amber Lee Cathey, Anita B. Reddy

Connect Tissue Res. Author manuscript; available in PMC 2014 Jul 10.

Published in final edited form as: Connect Tissue Res. 2013; 54(0): 275–282. Published online 2013 Jul 19. doi: 10.3109/03008207.2013.811236

PMCID:: PMC4091640

Abstract Article PDF–1.6M

Select item 39756834.

Thrombospondin-2 overexpression in the skin of transgenic mice reduces the susceptibility to chemically-induced multistep skin carcinogenesis

Rainer Kunstfeld, Thomas Hawighorst, Michael Streit, Young-Kwon Hong, Lynh Nguyen, Lawrence F. Brown, Michael Detmar

J Dermatol Sci. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: J Dermatol Sci. 2014 May; 74(2): 106–115. Published online 2014 Jan 18. doi: 10.1016/j.jdermsci.2014.01.002

PMCID:: PMC3975683

Abstract Article PDF–8.4M

Select item 37575655.

Oxidative stress-mediated thrombospondin-2 upregulation impairs bone marrow-derived angiogenic cell function in diabetes

Ok-Nam Bae, Jie-Mei Wang, Seung-Hoon Baek, Qingde Wang, Hong Yuan, Alex F. Chen

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Aug; 33(8): 1920–1927. Published online 2013 May 30. doi: 10.1161/ATVBAHA.113.301609

PMCID:: PMC3757565

Abstract Article PDF–2.9M

Select item 34013376.

Lack of Thrombospondin-2 Reduces Fibrosis and Increases Vascularity Around Cardiac Cell Grafts

Hans Reinecke, Thomas E. Robey, John Mignone, Veronica Muskheli, Paul Bornstein, Charles E. Murry

Cardiovasc Pathol. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Cardiovasc Pathol. 2013 Jan; 22(1): 91–95. Published online 2012 Apr 16. doi: 10.1016/j.carpath.2012.03.005

PMCID:: PMC3401337

Abstract Article PDF–1.8M

Select item 33749577.

Two Molecular Weight Species of Thrombospondin-2 Are Present in Bone and Differentially Modulated in Fractured and Nonfractured Tibiae in a Murine Model of Bone Healing

Andrea I. Alford, Anita B. Reddy, Steven A. Goldstein, Prithvi Murthy, Riyad Tayim, Gorav Sharma

Calcif Tissue Int. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Calcif Tissue Int. 2012 May; 90(5): 420–428. Published online 2012 Feb 24. doi: 10.1007/s00223-012-9580-y

PMCID:: PMC3374957

Abstract Article PDF–2.1M

Select item 29393028.

Thrombospodin-2 is an endogenous adipocyte inhibitor

Hailu S. Shitaye, Shawn P. Terkhorn, Jason A. Combs, Kurt D. Hankenson

Matrix Biol. Author manuscript; available in PMC 2011 Jul 1.

Published in final edited form as: Matrix Biol. 2010 Jul; 29(6): 549–556. Published online 2010 May 31. doi: 10.1016/j.matbio.2010.05.006

PMCID:: PMC2939302

Abstract Article PDF–2.2M

Select item 26739649.

Thrombospondin 2-null mice display an altered brain foreign body response to polyvinyl alcohol sponge implants

Weiming Tian, Themis R Kyriakides

Biomed Mater. Author manuscript; available in PMC 2010 Feb 1.

Published in final edited form as: Biomed Mater. 2009 Feb; 4(1): 15010. Published online 2008 Nov 20. doi: 10.1088/1748-6041/4/1/015010

PMCID:: PMC2673964

Abstract Article PDF–2.9M

Select item 266498410.

Enhanced Angiogenesis and Reduced Contraction in Thrombospondin-2–null Wounds Is Associated With Increased Levels of Matrix Metalloproteinases-2 and -9, and Soluble VEGF

Susan MacLauchlan, Eleni A. Skokos, Azin Agah, Jianmin Zeng, Weiming Tian, Jeffrey M. Davidson, Paul Bornstein, Themis R. Kyriakides

J Histochem Cytochem. 2009 Apr; 57(4): 301–313. doi: 10.1369/jhc.2008.952689

PMCID:: PMC2664984

Abstract Article PDF–2.2M

Select item 261361711.

Differential Interactions of Thrombospondin-1, -2, and -4 with CD47 and Effects on cGMP Signaling and Ischemic Injury Responses

Jeff S. Isenberg, Douglas S. Annis, Michael L. Pendrak, Malgorzata Ptaszynska, William A. Frazier, Deane F. Mosher, David D. Roberts

J Biol Chem. 2009 Jan 9; 284(2): 1116–1125. doi: 10.1074/jbc.M804860200

PMCID:: PMC2613617

Abstract Article PDF–668K

Select item 252707012.

Thrombospondin-2 Modulates Extracellular Matrix Remodeling during Physiological Angiogenesis

Marie M. Krady, Jianmin Zeng, Jun Yu, Susan MacLauchlan, Eleni A. Skokos, Weiming Tian, Paul Bornstein, William C. Sessa, Themis R. Kyriakides

Am J Pathol. 2008 Sep; 173(3): 879–891. doi: 10.2353/ajpath.2008.080128

PMCID:: PMC2527070

Abstract Article PDF–2.7M

Select item 185051513.

Altered Extracellular Matrix Remodeling and Angiogenesis in Sponge Granulomas of Thrombospondin 2-Null Mice

Themis R. Kyriakides, Yu-Hong Zhu, Zhantao Yang, Grace Huynh, Paul Bornstein

Am J Pathol. 2001 Oct; 159(4): 1255–1262. doi: 10.1016/S0002-9440(10)62512-6

PMCID:: PMC1850515

Abstract Article PDF–1.2M

Select item 160344514.

Proteolysis of Cell-Surface Tissue Transglutaminase by Matrix Metalloproteinase-2 Contributes to the Adhesive Defect and Matrix Abnormalities in Thrombospondin-2-Null Fibroblasts and Mice

Azin Agah, Themis R. Kyriakides, Paul Bornstein

Am J Pathol. 2005 Jul; 167(1): 81–88. doi: 10.1016/S0002-9440(10)62955-0

PMCID:: PMC1603445

Abstract Article PDF–858K

Select item 5256415.

A second thrombospondin gene in the mouse is similar in organization to thrombospondin 1 but does not respond to serum.

P Bornstein, S Devarayalu, P Li, C M Disteche, P Framson

Proc Natl Acad Sci U S A. 1991 Oct 1; 88(19): 8636–8640. doi: 10.1073/pnas.88.19.8636

PMCID:: PMC52564

Summary Page Browse PDF–1.0M

Select item 1635216.

Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity

Themis R. Kyriakides, Kathleen J. Leach, Allan S. Hoffman, Buddy D. Ratner, Paul Bornstein

Proc Natl Acad Sci U S A. 1999 Apr 13; 96(8): 4449–4454. doi: 10.1073/pnas.96.8.4449

PMCID:: PMC16352

Abstract Article PDF–444K

Select item 1106116417.

Heterozygous THBS2 pathogenic variant causes Ehlers–Danlos syndrome with prominent vascular features in humans and mice

Noam Hadar, Omri Porgador, Idan Cohen, Hilla Levi, Vadim Dolgin, Yuval Yogev, Sufa Sued-Hendrickson, Ilan Shelef, Elena Didkovsky, Marina Eskin-Schwartz, Ohad S. Birk

Eur J Hum Genet. 2024 May; 32(5): 550–557. Published online 2024 Mar 4. doi: 10.1038/s41431-024-01559-1