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Select item 111689331.

A disease-associated gene desert directs macrophage inflammation through ETS2

C. T. Stankey, C. Bourges, L. M. Haag, T. Turner-Stokes, A. P. Piedade, C. Palmer-Jones, I. Papa, M. Silva dos Santos, Q. Zhang, A. J. Cameron, A. Legrini, T. Zhang, C. S. Wood, F. N. New, L. O. Randzavola, L. Speidel, A. C. Brown, A. Hall, F. Saffioti, E. C. Parkes, W. Edwards, H. Direskeneli, P. C. Grayson, L. Jiang, P. A. Merkel, G. Saruhan-Direskeneli, A. H. Sawalha, E. Tombetti, A. Quaglia, D. Thorburn, J. C. Knight, A. P. Rochford, C. D. Murray, P. Divakar, M. Green, E. Nye, J. I. MacRae, N. B. Jamieson, P. Skoglund, M. Z. Cader, C. Wallace, D. C. Thomas, J. C. Lee

Nature. 2024; 630(8016): 447–456. Published online 2024 Jun 5. doi: 10.1038/s41586-024-07501-1

PMCID:: PMC11168933

Abstract Article PDF–45M

Select item 68185032.

ETS2 is a prostate basal cell marker and is highly expressed in prostate cancers aberrantly expressing p63

Alba Torres, Mohammed Alshalalfa, Elai Davicioni, Anuj Gupta, Srinivasan Yegnasubramanian, Sarah J. Wheelan, Jonathan I. Epstein, Angelo M. De Marzo, Tamara L. Lotan

Prostate. Author manuscript; available in PMC 2019 Oct 29.

Published in final edited form as: Prostate. 2018 Sep; 78(12): 896–904. Published online 2018 May 15. doi: 10.1002/pros.23646

PMCID:: PMC6818503

Abstract Article PDF–2.3M

Select item 60438333.

Differential Allelic Distribution of V-ets Erythroblastosis Virus E26 Oncogene Homolog2 (ETS2) Functional Polymorphisms in Different Group of Patients

Arpita Chatterjee, Samikshan Dutta, Sanjit Mukherjee, Nupur Mukherjee, Sharmila Chandra, Ashis Mukherjee, Swagata Sinha, Chinmay Kumar Panda, Keya Chaudhuri, Kanchan Mukhopadyay

Gene Expr. 2011; 15(2): 61–73. Published online 2018 Jul 13. doi: 10.3727/105221611x12973615737541

PMCID:: PMC6043833

Abstract Article PDF–767K

Select item 55181614.

High expression of ETS2 predicts poor prognosis in acute myeloid leukemia and may guide treatment decisions

Lin Fu, Huaping Fu, Qingyun Wu, Yifan Pang, Keman Xu, Lei Zhou, Jianlin Qiao, Xiaoyan Ke, Kailin Xu, Jinlong Shi

J Transl Med. 2017; 15: 159. Published online 2017 Jul 19. doi: 10.1186/s12967-017-1260-2

PMCID:: PMC5518161

Abstract Article PDF–1.4M

Select item 53086645.

Ets2 knockdown inhibits tumorigenesis in esophageal squamous cell carcinoma in vivo and in vitro

Qinghua Li, Lu Yang, Kang Han, Liqiang Zhu, Yanting Zhang, Shanshan Ma, Kun Zhang, Bo Yang, Fangxia Guan

Oncotarget. 2016 Sep 20; 7(38): 61458–61468. Published online 2016 Aug 18. doi: 10.18632/oncotarget.11369

PMCID:: PMC5308664

Abstract Article PDF–2.6M

Select item 49412896.

A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancer

Mi Jeong Hong, Shin Yup Lee, Jin Eun Choi, Cheng Cheng Jin, Hyo Jung Kang, Sun Ah Baek, So Yeon Lee, Kyung Min Shin, Ji Yun Jeong, Won Kee Lee, Seung Soo Yoo, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Ji Woong Son, Jae Yong Park

Oncotarget. 2016 Mar 29; 7(13): 15948–15958. Published online 2016 Feb 17. doi: 10.18632/oncotarget.7433

PMCID:: PMC4941289

Abstract Article PDF–2.2M

Select item 46113127.

Overexpression of ETS2 in human esophageal squamous cell carcinoma

Xin Li, Jia-Yun Lu, Li-Qun Zhao, Xiu-Qin Wang, Gui-Lin Liu, Zhong Liu, Chuan-Nong Zhou, Min Wu, Zhi-Hua Liu

World J Gastroenterol. 2003 Feb 15; 9(2): 205–208. Published online 2003 Feb 15. doi: 10.3748/wjg.v9.i2.205

PMCID:: PMC4611312

Abstract Article PDF–373K

Select item 43755038.

Structural Insights into the Autoregulation and Cooperativity of the Human Transcription Factor Ets-2

Joseph A Newman, Christopher D. O. Cooper, Hazel Aitkenhead, Opher Gileadi

J Biol Chem. 2015 Mar 27; 290(13): 8539–8549. Published online 2015 Feb 10. doi: 10.1074/jbc.M114.619270

PMCID:: PMC4375503

Abstract Article PDF–5.3M

Select item 38099199.

THE ROLE OF THE PROTO-ONCOGENE ETS2 IN ACUTE MEGAKARYOCYTIC LEUKEMIA BIOLOGY AND THERAPY

Yubin Ge, Katherine M. LaFiura, Alan A. Dombkowski, Qing Chen, Scott G. Payton, Steven A. Buck, Sridevi Salagrama, Amy E. Diakiw, Larry H. Matherly, Jeffrey W. Taub

Leukemia. Author manuscript; available in PMC 2013 Oct 28.

Published in final edited form as: Leukemia. 2008 Mar; 22(3): 10.1038/sj.leu.2405066. Published online 2007 Dec 20. doi: 10.1038/sj.leu.2405066

PMCID:: PMC3809919

Abstract Article PDF–700K

Select item 328530110.

Role for Ets-2^Thr-72 Transcription Factor in Stage-specific Thymocyte Development and Survival

Ian B. Fisher, Mike Ostrowski, Natarajan Muthusamy

J Biol Chem. 2012 Feb 17; 287(8): 5199–5210. Published online 2011 Nov 29. doi: 10.1074/jbc.M111.242602

PMCID:: PMC3285301

Abstract Article PDF–3.2M

Select item 1060465811.

USP39-Mediated Non-Proteolytic Control of ETS2 Suppresses Nuclear Localization and Activity

Yunsik Choi, Yuri Lee, Jin Seo Kim, Peijing Zhang, Jongchan Kim

Biomolecules. 2023 Oct; 13(10): 1475. Published online 2023 Oct 1. doi: 10.3390/biom13101475

PMCID:: PMC10604658

Abstract Article PDF–4.2M

Select item 705844512.

ΔNp73/ETS2 complex drives glioblastoma pathogenesis— targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma

Maren Cam, Manish Charan, Alessandra M Welker, Piyush Dravid, Adam W Studebaker, Jeffrey R Leonard, Christopher R Pierson, Ichiro Nakano, Christine E Beattie, Eugene I Hwang, Madhuri Kambhampati, Javad Nazarian, Jonathan L Finlay, Hakan Cam

Neuro Oncol. 2020 Mar; 22(3): 345–356. Published online 2019 Nov 25. doi: 10.1093/neuonc/noz190

PMCID:: PMC7058445

Abstract Article PDF–774K

Select item 669419213.

Association of Cyclin Dependent Kinase 10 and Transcription Factor 2 during Human Corneal Epithelial Wound Healing in vitro model

Meraj Zehra, Shamim Mushtaq, Syed Ghulam Musharraf, Rubina Ghani, Nikhat Ahmed

Sci Rep. 2019; 9: 11802. Published online 2019 Aug 14. doi: 10.1038/s41598-019-48092-6

Correction in:: Sci Rep. 2020; 10: 14405.

PMCID:: PMC6694192

Abstract Article PDF–4.1M

Select item 503186714.

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia

Jason R. Pitarresi, Xin Liu, Sudarshana M. Sharma, Maria C. Cuitiño, Raleigh D. Kladney, Thomas A. Mace, Sydney Donohue, Sunayana G. Nayak, Chunjing Qu, James Lee, Sarah A. Woelke, Stefan Trela, Kyle LaPak, Lianbo Yu, Joseph McElroy, Thomas J. Rosol, Reena Shakya, Thomas Ludwig, Gregory B. Lesinski, Soledad A. Fernandez, Stephen F. Konieczny, Gustavo Leone, Jinghai Wu, Michael C. Ostrowski

Neoplasia. 2016 Sep; 18(9): 541–552. Published online 2016 Sep 20. doi: 10.1016/j.neo.2016.07.006

PMCID:: PMC5031867

Abstract Article PDF–3.3M

Select item 485396115.

The C-ETS2-TFEB Axis Promotes Neuron Survival under Oxidative Stress by Regulating Lysosome Activity

Shumin Ma, Zijun Fang, Wenwen Luo, Yunzhi Yang, Chenyao Wang, Qian Zhang, Huafei Wang, Huaiyong Chen, Chi bun Chan, Zhixue Liu

Oxid Med Cell Longev. 2016; 2016: 4693703. Published online 2016 Apr 19. doi: 10.1155/2016/4693703

PMCID:: PMC4853961

Abstract Article PDF–7.5M

Select item 384643416.

ETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer

Mohamed Kabbout, Melinda M. Garcia, Junya Fujimoto, Diane D. Liu, Denise Woods, Chi-Wan Chow, Gabriela Mendoza, Amin A. Momin, Brian P. James, Luisa Solis, Carmen Behrens, J. Jack Lee, Ignacio I. Wistuba, Humam Kadara

Clin Cancer Res. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Clin Cancer Res. 2013 Jul 1; 19(13): 10.1158/1078-0432.CCR-13-0341. Published online 2013 May 9. doi: 10.1158/1078-0432.CCR-13-0341

PMCID:: PMC3846434

Abstract Article PDF–1.4M

Select item 382690517.

Exploratory Investigation on Functional Significance of ETS2 and SIM2 Genes in Down Syndrome

Arpita Chatterjee, Samikshan Dutta, Swagata Sinha, Kanchan Mukhopadhyay

Dis Markers. 2011; 31(5): 247–257. Published online 2011 Nov 1. doi: 10.3233/DMA-2011-0825

PMCID:: PMC3826905

Summary PDF–986K

Select item 374545718.

Ets2 in Tumor Fibroblasts Promotes Angiogenesis in Breast Cancer

Julie A. Wallace, Fu Li, Subhasree Balakrishnan, Carmen Z. Cantemir-Stone, Thierry Pecot, Chelsea Martin, Raleigh D. Kladney, Sudarshana M. Sharma, Anthony J. Trimboli, Soledad A. Fernandez, Lianbo Yu, Thomas J. Rosol, Paul C. Stromberg, Robert Lesurf, Michael Hallett, Morag Park, Gustavo Leone, Michael C. Ostrowski

PLoS One. 2013; 8(8): e71533. Published online 2013 Aug 16. doi: 10.1371/journal.pone.0071533

PMCID:: PMC3745457

Abstract Article PDF–3.1M

Select item 356352219.

Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies

Arpita Chatterjee, Samikshan Dutta, Sanjit Mukherjee, Nupur Mukherjee, Avirup Dutta, Ashis Mukherjee, Swagata Sinha, Chinmay Kumar Panda, Keya Chaudhuri, Ananda L Roy, Kanchan Mukhopadhyay

BMC Med Genet. 2013; 14: 12. Published online 2013 Jan 23. doi: 10.1186/1471-2350-14-12

PMCID:: PMC3563522

Abstract Article PDF–910K

Select item 332444120.

Transcriptional regulation of miR-196b by ETS2 in gastric cancer cells

Yu-Lun Liao, Ling-Yueh Hu, Kuo-Wang Tsai, Chew-Wun Wu, Wen-Ching Chan, Sung-Chou Li, Chun-Hung Lai, Meng-Ru Ho, Wen-Liang Fang, Kuo-Hung Huang, Wen-chang Lin

Carcinogenesis. 2012 Apr; 33(4): 760–769. Published online 2012 Jan 31. doi: 10.1093/carcin/bgs023

PMCID:: PMC3324441

Abstract Article PDF–822K

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