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Select item 104424581.

ERG Status at the Margin is Associated with Biochemical Recurrence after Radical Prostatectomy with Positive Surgical Margins

Daniela C. Salles, Adrianna A. Mendes, Misop Han, Alan W. Partin, Bruce J. Trock, Yuezhou Jing, Tamara L. Lotan

Mod Pathol. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Mod Pathol. 2023 Jul; 36(7): 100147. Published online 2023 Feb 22. doi: 10.1016/j.modpat.2023.100147

PMCID:: PMC10442458

Abstract Article PDF–764K

Select item 93485992.

In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis

Susanne G. Kidd, Mari Bogaard, Kristina T. Carm, Anne Cathrine Bakken, Aase M. V. Maltau, Marthe Løvf, Ragnhild A. Lothe, Karol Axcrona, Ulrika Axcrona, Rolf I. Skotheim

Mol Oncol. 2022 Aug; 16(15): 2810–2822. Published online 2022 Jun 18. doi: 10.1002/1878-0261.13225

PMCID:: PMC9348599

Abstract Article PDF–1.9M

Select item 91053693.

The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of Prostate Cancer

Ealia Khosh Kish, Muhammad Choudhry, Yaser Gamallat, Sabrina Marsha Buharideen, Dhananjaya D, Tarek A. Bismar

Int J Mol Sci. 2022 May; 23(9): 4772. Published online 2022 Apr 26. doi: 10.3390/ijms23094772

PMCID:: PMC9105369

Abstract Article PDF–1.0M

Select item 87486754.

Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states

Hanbing Song, Hannah N. W. Weinstein, Paul Allegakoen, Marc H. Wadsworth, II, Jamie Xie, Heiko Yang, Ethan A. Castro, Kevin L. Lu, Bradley A. Stohr, Felix Y. Feng, Peter R. Carroll, Bruce Wang, Matthew R. Cooperberg, Alex K. Shalek, Franklin W. Huang

Nat Commun. 2022; 13: 141. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27322-4

PMCID:: PMC8748675

Abstract Article PDF–12M

Select item 83458715.

Ras/ERK and PI3K/AKT signaling differentially regulate oncogenic ERG mediated transcription in prostate cells

Brady G. Strittmatter, Travis J. Jerde, Peter C. Hollenhorst

PLoS Genet. 2021 Jul; 17(7): e1009708. Published online 2021 Jul 27. doi: 10.1371/journal.pgen.1009708

PMCID:: PMC8345871

Abstract Article PDF–3.5M

Select item 81241126.

Expression and ERG regulation of PIM kinases in prostate cancer

Sini K. Eerola, Annika Kohvakka, Teuvo L. J. Tammela, Päivi J. Koskinen, Leena Latonen, Tapio Visakorpi

Cancer Med. 2021 May; 10(10): 3427–3436. Published online 2021 May 1. doi: 10.1002/cam4.3893

PMCID:: PMC8124112

Abstract Article PDF–847K

Select item 70680297.

A non-coding genetic variant associated with abdominal aortic aneurysm alters ERG gene regulation

Judith Marsman, Gregory Gimenez, Robert C Day, Julia A Horsfield, Gregory T Jones

Hum Mol Genet. 2020 Mar 13; 29(4): 554–565. Published online 2019 Nov 6. doi: 10.1093/hmg/ddz256

PMCID:: PMC7068029

Abstract Article PDF–1.0M

Select item 68807478.

ERG TRANSCRIPTION FACTOR AS AN IMMUNOHISTOCHEMICAL MARKER FOR VASCULAR ENDOTHELIAL TUMORS AND PROSTATIC CARCINOMA

Markku Miettinen, Zeng-Feng Wang, Anders Paetau, Shyh-Han Tan, Albert Dobi, Shiv Srivastava, Isabell Sesterhenn

Am J Surg Pathol. Author manuscript; available in PMC 2019 Nov 27.

Published in final edited form as: Am J Surg Pathol. 2011 Mar; 35(3): 432–441. doi: 10.1097/PAS.0b013e318206b67b

PMCID:: PMC6880747

Abstract Article PDF–3.0M

Select item 68589949.

Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome

Adam J. de Smith, Kyle M. Walsh, Libby M. Morimoto, Stephen S. Francis, Helen M. Hansen, Soyoung Jeon, Semira Gonseth, Minhui Chen, Hanxiao Sun, Sandra Luna-Fineman, Federico Antillón, Verónica Girón, Alice Y. Kang, Ivan Smirnov, Xiaorong Shao, Todd P. Whitehead, Lisa F. Barcellos, Kent W. Jolly, Jasmine Healy, Caroline Laverdière, Daniel Sinnett, Jeffrey W. Taub, Jillian M. Birch, Pamela D. Thompson, Maria S. Pombo-de-Oliveira, Logan G. Spector, Andrew T. DeWan, Beth A. Mueller, Charleston Chiang, Catherine Metayer, Xiaomei Ma, Joseph L. Wiemels

Leukemia. 2019; 33(11): 2746–2751. Published online 2019 Jul 11. doi: 10.1038/s41375-019-0514-9

PMCID:: PMC6858994

Article PDF–979K

Select item 685671710.

Potent hERG channel inhibition by sarizotan, an investigative treatment for Rett Syndrome

Hongwei Cheng, Chunyun Du, Yihong Zhang, Andrew F. James, Christopher E. Dempsey, Ana P. Abdala, Jules C. Hancox

J Mol Cell Cardiol. 2019 Oct; 135: 22–30. doi: 10.1016/j.yjmcc.2019.07.012

PMCID:: PMC6856717

Abstract Article

Select item 672649611.

Aberrant expression of ERG promotes resistance to combined PI3K and AR pathway inhibition through maintenance of AR target genes

Ninghui Mao, Dong Gao, Wenhuo Hu, Haley Hieronymus, Shangqian Wang, Young Sun Lee, Cindy Lee, Danielle Choi, Anuradha Gopalan, Yu Chen, Brett S Carver

Mol Cancer Ther. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Mol Cancer Ther. 2019 Sep; 18(9): 1577–1586. Published online 2019 Jul 11. doi: 10.1158/1535-7163.MCT-18-1386

PMCID:: PMC6726496

Abstract Article PDF–1.7M

Select item 649368612.

The Transcription Factor ERG Regulates Super-Enhancers Associated With an Endothelial-Specific Gene Expression Program

Viktoria Kalna, Youwen Yang, Claire R. Peghaire, Karen Frudd, Rebecca Hannah, Aarti V. Shah, Lourdes Osuna Almagro, Joseph J. Boyle, Berthold Göttgens, Jorge Ferrer, Anna M. Randi, Graeme M. Birdsey

Circ Res. 2019 Apr 26; 124(9): 1337–1349. Published online 2019 Mar 20. doi: 10.1161/CIRCRESAHA.118.313788

PMCID:: PMC6493686

Abstract Article PDF–5.3M

Select item 642936613.

5hmC Level Predicts Biochemical Failure Following Radical Prostatectomy in Prostate Cancer Patients with ERG Negative Tumors

Gitte Kristensen, Siri H. Strand, Martin Andreas Røder, Kasper Drimer Berg, Birgitte Grønkær Toft, Søren Høyer, Michael Borre, Karina Dalsgaard Sørensen, Klaus Brasso

Int J Mol Sci. 2019 Mar; 20(5): 1025. Published online 2019 Feb 27. doi: 10.3390/ijms20051025

PMCID:: PMC6429366

Abstract Article PDF–1.4M

Select item 637627814.

Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics

Maoxiang Qian, Heng Xu, Virginia Perez-Andreu, Kathryn G. Roberts, Hui Zhang, Wenjian Yang, Shouyue Zhang, Xujie Zhao, Colton Smith, Meenakshi Devidas, Julie M. Gastier-Foster, Elizabeth Raetz, Eric Larsen, Esteban G. Burchard, Naomi Winick, W. Paul Bowman, Paul L. Martin, Michael Borowitz, Brent Wood, Federico Antillon-Klussmann, Ching-Hon Pui, Charles G. Mullighan, William E. Evans, Stephen P. Hunger, Mary V. Relling, Mignon L. Loh, Jun J. Yang

Blood. 2019 Feb 14; 133(7): 724–729. Prepublished online 2018 Dec 3. doi: 10.1182/blood-2018-07-862946

PMCID:: PMC6376278

Abstract Article

Select item 636504415.

Human ether-à-go-go-related gene mutation L539fs/47-hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun

Int J Mol Med. 2019 Mar; 43(3): 1253–1262. Published online 2019 Jan 2. doi: 10.3892/ijmm.2019.4049

PMCID:: PMC6365044

Abstract Article PDF–1.0M

Select item 633939616.

ERG oncoprotein expression in prostatic acinar adenocarcinoma; clinicopathologic significance

Atif Ali Hashmi, Erum Yousuf Khan, Muhammad Irfan, Rabia Ali, Huda Asif, Maheen Naeem, Laila Nisar, Naveen Faridi, Amir Khan, Muhammad Muzzammil Edhi

BMC Res Notes. 2019; 12: 35. Published online 2019 Jan 18. doi: 10.1186/s13104-019-4090-x

PMCID:: PMC6339396

Abstract Article PDF–932K

Select item 589481417.

MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation

Y Huang, JAI Thoms, ML Tursky, K Knezevic, D Beck, V Chandrakanthan, S Suryani, J Olivier, A Boulton, EN Glaros, SR Thomas, RB Lock, KL MacKenzie, JH Bushweller, JWH Wong, JE Pimanda

Leukemia. Author manuscript; available in PMC 2018 Apr 11.

Published in final edited form as: Leukemia. 2016 Jul; 30(7): 1552–1561. Published online 2016 Mar 8. doi: 10.1038/leu.2016.55

PMCID:: PMC5894814

Abstract Article PDF–866K

Select item 565550218.

Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2, allowing target gene activation

Vivekananda Kedage, Brady G. Strittmatter, Paige B. Dausinas, Peter C. Hollenhorst

J Biol Chem. 2017 Oct 20; 292(42): 17225–17235. Published online 2017 Sep 8. doi: 10.1074/jbc.M117.796458

PMCID:: PMC5655502

Abstract Article PDF–1.7M

Select item 528296419.

Noninvasive Prenatal Diagnosis Significance of ERG Methylation as a Biomarker in Down’s Syndrome

Xiangju Liu, Ming Xue

Med Sci Monit. 2017; 23: 398–404. Published online 2017 Jan 23. doi: 10.12659/MSM.898687

PMCID:: PMC5282964

Abstract Article PDF–1.6M

Select item 522315520.

Comprehensive study on ERG gene expression in normal karyotype acute myeloid leukemia: ERG expression is of limited prognostic value, whereas the accumulation of adverse prognostic markers stepwise worsens the prognosis

S Weber, T Haferlach, C Haferlach, W Kern

Blood Cancer J. 2016 Dec; 6(12): e507. Published online 2016 Dec 9. doi: 10.1038/bcj.2016.120

PMCID:: PMC5223155

Article PDF–453K

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