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Select item 105432711.

EYA4 promotes breast cancer progression and metastasis through its role in replication stress avoidance

Bárbara de la Peña Avalos, Romain Tropée, Pascal H. G. Duijf, Eloïse Dray

Mol Cancer. 2023; 22: 158. Published online 2023 Sep 30. doi: 10.1186/s12943-023-01861-4

PMCID:: PMC10543271

Abstract Article PDF–9.5M

Select item 98435102.

Aberrant DNA methylation and expression of EYA4 in gastric cardia intestinal metaplasia

Chenxi Li, Zhaohui Liu, Guohua Xu, Shibin Wu, Yunhui Peng, Ruinuan Wu, Shukun Zhao, Xiaoqi Liao, Runhua Lin

Saudi J Gastroenterol. 2022 Nov-Dec; 28(6): 456–465. Published online 2022 Nov 4. doi: 10.4103/sjg.sjg_228_22

PMCID:: PMC9843510

Abstract Article PDF–7.9M

Select item 91094013.

Identification of a novel CNV at the EYA4 gene in a Chinese family with autosomal dominant nonsyndromic hearing loss

Weixun Zhang, Jing Song, Busheng Tong, Mengye Ma, Luo Guo, Yasheng Yuan, Juanmei Yang

BMC Med Genomics. 2022; 15: 113. Published online 2022 May 16. doi: 10.1186/s12920-022-01269-x

PMCID:: PMC9109401

Abstract Article PDF–1.0M

Select item 79634304.

Early truncation of the N‐terminal variable region of EYA4 gene causes dominant hearing loss without cardiac phenotype

Yanfang Mi, Danhua Liu, Beiping Zeng, Yongan Tian, Hui Zhang, Bei Chen, Juanli Zhang, Hong Xue, Wenxue Tang, Yulin Zhao, Hongen Xu

Mol Genet Genomic Med. 2021 Jan; 9(1): e1569. Published online 2020 Dec 10. doi: 10.1002/mgg3.1569

PMCID:: PMC7963430

Abstract Article PDF–997K

Select item 71483445.

Insights into the pathophysiology of DFNA10 hearing loss associated with novel EYA4 variants

Matias Morín, Lucía Borreguero, Kevin T Booth, María Lachgar, Patrick Huygen, Manuela Villamar, Fernando Mayo, Luis Carlos Barrio, Luciana Santos Serrão de Castro, Carmelo Morales, Ignacio del Castillo, Beatriz Arellano, Dolores Tellería, Richard J. H. Smith, Hela Azaiez, M. A. Moreno Pelayo

Sci Rep. 2020; 10: 6213. Published online 2020 Apr 10. doi: 10.1038/s41598-020-63256-5

PMCID:: PMC7148344

Abstract Article PDF–2.6M

Select item 70466596.

Prevalence and clinical features of hearing loss caused by EYA4 variants

Jun Shinagawa, Hideaki Moteki, Shin-ya Nishio, Kenji Ohyama, Koshi Otsuki, Satoshi Iwasaki, Shin Masuda, Chie Oshikawa, Yumi Ohta, Yasuhiro Arai, Masahiro Takahashi, Naoko Sakuma, Satoko Abe, Yuika Sakurai, Hirofumi Sakaguchi, Takashi Ishino, Natsumi Uehara, Shin-ichi Usami

Sci Rep. 2020; 10: 3662. Published online 2020 Feb 27. doi: 10.1038/s41598-020-60259-0

PMCID:: PMC7046659

Abstract Article PDF–1.7M

Select item 65335157.

EYA4 serves as a prognostic biomarker in hepatocellular carcinoma and suppresses tumour angiogenesis and metastasis

Fangming Gu, Shengxian Yuan, Lei Liu, Peng Zhu, Yuan Yang, Zeya Pan, Weiping Zhou

J Cell Mol Med. 2019 Jun; 23(6): 4208–4216. Published online 2019 Apr 7. doi: 10.1111/jcmm.14309

PMCID:: PMC6533515

Abstract Article PDF–1.8M

Select item 59898458.

Aberrant methylation of EYA4 promotes epithelial‐mesenchymal transition in esophageal squamous cell carcinoma

Mei Luo, Yuan Li, Xuejiao Shi, Wenhui Yang, Fang Zhou, Nan Sun, Jie He

Cancer Sci. 2018 Jun; 109(6): 1811–1824. Published online 2018 May 26. doi: 10.1111/cas.13615

PMCID:: PMC5989845

Abstract Article PDF–6.5M

Select item 49661699.

EYA4 gene functions as a prognostic marker and inhibits the growth of intrahepatic cholangiocarcinoma

Xiao-Yi Hao, Jian-Peng Cai, Xin Liu, Wei Chen, Xun Hou, Dong Chen, Jia-ming Lai, Li-Jian Liang, Xiao-Yu Yin

Chin J Cancer. 2016; 35: 70. Published online 2016 Jul 28. doi: 10.1186/s40880-016-0133-z

PMCID:: PMC4966169

Abstract Article PDF–2.5M

Select item 489404810.

Epigenetic Silencing of Eyes Absent 4 Gene by Acute Myeloid Leukemia 1-Eight-twenty-one Oncoprotein Contributes to Leukemogenesis in t(8;21) Acute Myeloid Leukemia

Sai Huang, Meng-Meng Jiang, Guo-Feng Chen, Kun Qian, Hong-Hao Gao, Wei Guan, Jin-Long Shi, An-Qi Liu, Jing Liu, Bian-Hong Wang, Yong-Hui Li, Li Yu

Chin Med J (Engl) 2016 Jun 5; 129(11): 1355–1362. doi: 10.4103/0366-6999.182838

PMCID:: PMC4894048

Abstract Article PDF–2.1M

Select item 452753411.

EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk

Ian M. Wilson, Emily A. Vucic, Katey S.S. Enfield, Kelsie L. Thu, Yu-An Zhang, Raj Chari, William W. Lockwood, Niki Radulovich, Daniel T. Starczynowski, Judit P. Banáth, May Zhang, Andrea Pusic, Megan Fuller, Kim M. Lonergan, David Rowbotham, John Yee, John C. English, Timon P.H. Buys, Suhaida A. Selamat, Ite A. Laird-Offringa, Pengyuan Liu, Marshall Anderson, Ming You, Ming-Sound Tsao, Carolyn J. Brown, Kevin L. Bennewith, Calum E. MacAulay, Aly Karsan, Adi F. Gazdar, Stephen Lam, Wan L. Lam

Oncogene. Author manuscript; available in PMC 2015 Aug 6.

Published in final edited form as: Oncogene. 2014 Sep 4; 33(36): 4464–4473. Published online 2013 Oct 7. doi: 10.1038/onc.2013.396

PMCID:: PMC4527534

Abstract Article PDF–1.2M

Select item 444853512.

A novel EYA4 mutation causing hearing loss in a Chinese DFNA family and genotype-phenotype review of EYA4 in deafness

Aiping Huang, Yongyi Yuan, Yanping Liu, Qingwen Zhu, Pu Dai

J Transl Med. 2015; 13: 154. Published online 2015 May 12. doi: 10.1186/s12967-015-0483-3

PMCID:: PMC4448535

Abstract Article PDF–2.4M

Select item 442728913.

Exome Sequencing Identifies a Mutation in EYA4 as a Novel Cause of Autosomal Dominant Non-Syndromic Hearing Loss

Fei Liu, Jiongjiong Hu, Wenjun Xia, Lili Hao, Jing Ma, Duan Ma, Zhaoxin Ma

PLoS One. 2015; 10(5): e0126602. Published online 2015 May 11. doi: 10.1371/journal.pone.0126602

PMCID:: PMC4427289

Abstract Article PDF–2.4M

Select item 436347814.

Evaluation of the Contribution of the EYA4 and GRHL2 Genes in Korean Patients with Autosomal Dominant Non-Syndromic Hearing Loss

Ye-Ri Kim, Min-A Kim, Borum Sagong, Seung-Hyun Bae, Hyo-Jeong Lee, Hyung-Jong Kim, Jae Young Choi, Kyu-Yup Lee, Un-Kyung Kim

PLoS One. 2015; 10(3): e0119443. Published online 2015 Mar 17. doi: 10.1371/journal.pone.0119443

PMCID:: PMC4363478

Abstract Article PDF–867K

Select item 421433115.

Identification of I411K, a novel missense EYA4 mutation causing autosomal dominant non-syndromic hearing loss

MINXING TAN, XIAOFEI SHEN, JUN YAO, QINJUN WEI, YAJIE LU, XIN CAO, GUANGQIAN XING

Int J Mol Med. 2014 Dec; 34(6): 1467–1472. Published online 2014 Sep 19. doi: 10.3892/ijmm.2014.1939

PMCID:: PMC4214331

Abstract Article PDF–438K

Select item 411994416.

Methylated Eyes Absent 4 (EYA4) Gene Promotor in Non-neoplastic Mucosa of Ulcerative Colitis Patients with Colorectal Cancer: Evidence for a Field Effect

John B. Kisiel, Megan M. Garrity-Park, William R. Taylor, Thomas C. Smyrk, David A. Ahlquist

Inflamm Bowel Dis. Author manuscript; available in PMC 2014 Aug 4.

Published in final edited form as: Inflamm Bowel Dis. 2013 Sep; 19(10): 2079–2083. doi: 10.1097/MIB.0b013e31829b3f4d

PMCID:: PMC4119944

Abstract Article PDF–506K

Select item 203994717.

A 4-bp insertion in the eya-homologous region (eyaHR) of EYA4 causes hearing impairment in a Hungarian family linked to DFNA10.

Markus Pfister, Tímea Tóth, Holger Thiele, Birgit Haack, Nikolaus Blin, Hans-Peter Zenner, István Sziklai, Peter Nürnberg, Susan Kupka

Mol Med. 2002 Oct; 8(10): 607–611.

PMCID:: PMC2039947

Summary PDF–83K

Select item 652424718.

Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis

Wei Dong, Junming Bi, Hongwei Liu, Dong Yan, Qingqing He, Qianghua Zhou, Qiong Wang, Ruihui Xie, Yinjie Su, Meihua Yang, Tianxin Lin, Jian Huang

Mol Cancer. 2019; 18: 95. Published online 2019 May 17. doi: 10.1186/s12943-019-1025-z

PMCID:: PMC6524247

Abstract Article PDF–17M

Select item 308450819.

Genome-Wide Association Study of Genetic Predictors of Anti–Tumor Necrosis Factor Treatment Efficacy in Rheumatoid Arthritis Identifies Associations with Polymorphisms at Seven Loci

Darren Plant, John Bowes, Catherine Potter, Kimme L Hyrich, Ann W Morgan, Anthony G Wilson, John D Isaacs, Anne Barton, Wellcome Trust Case Control Consortium, the British Society for Rheumatology Biologics Register

Arthritis Rheum. 2011 Mar; 63(3): 645–653. doi: 10.1002/art.30130

PMCID:: PMC3084508

Abstract Article PDF–85K

Select item 278972720.

Relationship between the expression of hTERT and EYA4 mRNA in peripheral blood mononuclear cells with the progressive stages of carcinogenesis of the esophagus

Hao Li, Tao Yu Diao, Zhi Ying Zhou, Fang Yan Yang, Qing Ma, Qing Hui Li

J Exp Clin Cancer Res. 2009; 28(1): 145. Published online 2009 Nov 25. doi: 10.1186/1756-9966-28-145

PMCID:: PMC2789727

Abstract Article PDF–298K

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