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Items: 1 to 20 of 80

1.
Sortilin deletion in the prefrontal cortex and hippocampus ameliorates depressive-like behaviors in mice via regulating ASM/ceramide signaling
Shu-jian Chen, Cong-cong Gao, Qun-yu Lv, Meng-qi Zhao, Xiao-ying Qin, Hong Liao
Acta Pharmacol Sin. 2022 Aug; 43(8): 1940–1954. Published online 2021 Dec 20. doi: 10.1038/s41401-021-00823-0
PMCID:
PMC9343424
AbstractArticlePDF–6.3M
2.
Identification of Sortilin Alternatively Spliced Variants in Mouse 3T3L1 Adipocytes
Ashley Lui, Robert Sparks, Rekha Patel, Niketa A. Patel
Int J Mol Sci. 2021 Feb; 22(3): 983. Published online 2021 Jan 20. doi: 10.3390/ijms22030983
PMCID:
PMC7863940
AbstractArticlePDF–2.9M
3.
Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice
Cheng Chen, Jibiao Li, David J. Matye, Yifeng Wang, Tiangang Li
J Lipid Res. 2019 Mar; 60(3): 539–549. Published online 2019 Jan 22. doi: 10.1194/jlr.M089789
PMCID:
PMC6399493
AbstractArticlePDF–1.7M
4.
Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release
Nadia Leloup, Philip Lössl, Dimphna H. Meijer, Martha Brennich, Albert J. R. Heck, Dominique M. E. Thies-Weesie, Bert J. C. Janssen
Nat Commun. 2017; 8: 1708. Published online 2017 Nov 22. doi: 10.1038/s41467-017-01485-5
PMCID:
PMC5700061
AbstractArticlePDF–2.6M
5.
Sortilin 1 knockout alters basal adipose glucose metabolism but not diet-induced obesity in mice
Jibiao Li, David J. Matye, Yifeng Wang, Tiangang Li
FEBS Lett. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: FEBS Lett. 2017 Apr; 591(7): 1018–1028. Published online 2017 Mar 16. doi: 10.1002/1873-3468.12610
PMCID:
PMC5423541
AbstractArticlePDF–1.1M
6.
Increased Brain Neurotensin and NTSR2 Lead to Weak Nociception in NTSR3/Sortilin Knockout Mice
Christelle Devader, Sébastien Moreno, Morgane Roulot, Emmanuel Deval, Thomas Dix, Carlos R. Morales, Jean Mazella
Front Neurosci. 2016; 10: 542. Published online 2016 Nov 24. doi: 10.3389/fnins.2016.00542
PMCID:
PMC5121284
AbstractArticlePDF–881K
7.
The proneurotrophin receptor sortilin is required for Mycobacterium tuberculosis control by macrophages
Cristina L. Vázquez, Angela Rodgers, Susanne Herbst, Stephen Coade, Achim Gronow, Carlos A. Guzman, Mark S. Wilson, Makoto Kanzaki, Anders Nykjaer, Maximiliano G. Gutierrez
Sci Rep. 2016; 6: 29332. Published online 2016 Jul 8. doi: 10.1038/srep29332
PMCID:
PMC4937236
AbstractArticlePDF–3.1M
8.
TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin
Toshiki Yabe-Wada, Shintaro Matsuba, Kazuya Takeda, Tetsuya Sato, Mikita Suyama, Yasuyuki Ohkawa, Toshiyuki Takai, Haifeng Shi, Caroline C. Philpott, Akira Nakamura
Sci Rep. 2016; 6: 26566. Published online 2016 May 25. doi: 10.1038/srep26566
PMCID:
PMC4879639
AbstractArticlePDF–1.6M
9.
Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation
Simona Capsoni, Gianluca Amato, Domenico Vignone, Chiara Criscuolo, Anders Nykjaer, Antonino Cattaneo
Biochem Biophys Res Commun. 2013 Feb 15; 431(3): 579–585. doi: 10.1016/j.bbrc.2013.01.007
PMCID:
PMC3585961
AbstractArticle
10.
Sortilin Participates in Light-dependent Photoreceptor Degeneration in Vivo
Ana M. Santos, Noelia López-Sánchez, David Martín-Oliva, Pedro de la Villa, Miguel A. Cuadros, José M. Frade
PLoS One. 2012; 7(4): e36243. Published online 2012 Apr 27. doi: 10.1371/journal.pone.0036243
PMCID:
PMC3338683
AbstractArticlePDF–4.3M
11.
Characterization of Insulin-Responsive GLUT4 Storage Vesicles Isolated from 3T3-L1 Adipocytes
Mitsuru Hashiramoto, David E. James
Mol Cell Biol. 2000 Jan; 20(1): 416–427. doi: 10.1128/mcb.20.1.416-427.2000
PMCID:
PMC85096
AbstractArticlePDF–1.7M
12.
Sortilin enhances secretion of apolipoprotein(a) through effects on apolipoprotein B secretion and promotes uptake of lipoprotein(a)
Justin R. Clark, Matthew Gemin, Amer Youssef, Santica M. Marcovina, Annik Prat, Nabil G. Seidah, Robert A. Hegele, Michael B. Boffa, Marlys L. Koschinsky
J Lipid Res. 2022 Jun; 63(6): 100216. Published online 2022 Apr 22. doi: 10.1016/j.jlr.2022.100216
PMCID:
PMC9131257
AbstractArticlePDF–3.8M
13.
PCBP2 post‐transcriptionally regulates sortilin expression by binding to a C‐rich element in its 3′ UTR
Toshiki Yabe‐Wada, Caroline C. Philpott, Nobuyuki Onai
FEBS Open Bio. 2020 Mar; 10(3): 407–413. Published online 2020 Feb 3. doi: 10.1002/2211-5463.12794
PMCID:
PMC7050257
AbstractArticlePDF–1.0M
14.
PAK Kinases Target Sortilin and Modulate Its Sorting
Lone Tjener Pallesen, Camilla Gustafsen, Jacob Flyvholm Cramer, Steen Vang Petersen, Søren Skou Thirup, Peder Madsen, Claus Munck Petersen
Mol Cell Biol. 2020 Feb; 40(3): e00411-19. Prepublished online 2019 Nov 25. Published online 2020 Jan 16. doi: 10.1128/MCB.00411-19
PMCID:
PMC6965034
AbstractArticlePDF–2.1M
15.
Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin
Sumihiko Hagita, Maximillian A. Rogers, Tan Pham, Jennifer R. Wen, Andrew K. Mlynarchik, Masanori Aikawa, Elena Aikawa
Sci Rep. 2018; 8: 9006. Published online 2018 Jun 13. doi: 10.1038/s41598-018-27416-y
PMCID:
PMC5998044
AbstractArticlePDF–2.2M
16.
Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility
Diana C. Parrish, Samantha D. Francis Stuart, Antoinette Olivas, Lianguo Wang, Anders Nykjaer, Crystal M. Ripplinger, Beth A. Habecker
Am J Physiol Heart Circ Physiol. 2018 Mar 1; 314(3): H415–H423. Published online 2017 Nov 3. doi: 10.1152/ajpheart.00300.2017
PMCID:
PMC5899257
AbstractArticle
17.
Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes
Jibiao Li, Cheng Chen, Yuan Li, David J. Matye, Yifeng Wang, Wen-Xing Ding, Tiangang Li
Biochim Biophys Acta. Author manuscript; available in PMC 2018 Nov 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Nov; 1863(11): 2924–2933. Published online 2017 Aug 24. doi: 10.1016/j.bbadis.2017.08.012
PMCID:
PMC5659898
AbstractArticlePDF–3.2M
18.
Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1
Jibiao Li, Yifeng Wang, David J. Matye, Hemantkumar Chavan, Partha Krishnamurthy, Feng Li, Tiangang Li
J Biol Chem. 2017 Jan 6; 292(1): 146–160. Published online 2016 Nov 23. doi: 10.1074/jbc.M116.762005
PMCID:
PMC5217674
AbstractArticlePDF–4.5M
19.
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification
Claudia Goettsch, Joshua D. Hutcheson, Sumihiko Hagita, Maximillian A. Rogers, Michael D. Creager, Tan Pham, Jung Choi, Andrew K Mlynarchik, Brett Pieper, Mads Kjolby, Masanori Aikawa, Elena Aikawa
Atherosclerosis. Author manuscript; available in PMC 2017 Feb 1.
Published in final edited form as: Atherosclerosis. 2016 Aug; 251: 109–118. Published online 2016 Jun 9. doi: 10.1016/j.atherosclerosis.2016.06.011
PMCID:
PMC4983246
AbstractArticlePDF–2.4M
20.
Insulin Resistance Induces Posttranslational Hepatic Sortilin 1 Degradation in Mice
Jibiao Li, David J. Matye, Tiangang Li
J Biol Chem. 2015 May 1; 290(18): 11526–11536. Published online 2015 Mar 23. doi: 10.1074/jbc.M115.641225
PMCID:
PMC4416856
AbstractArticlePDF–1.8M

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