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Select item 111370271.

Acute depletion of BRG1 reveals its primary function as an activator of transcription

Gang Ren, Wai Lim Ku, Guangzhe Ge, Jackson A. Hoffman, Jee Youn Kang, Qingsong Tang, Kairong Cui, Yong He, Yukun Guan, Bin Gao, Chengyu Liu, Trevor K. Archer, Keji Zhao

Nat Commun. 2024; 15: 4561. Published online 2024 May 29. doi: 10.1038/s41467-024-48911-z

PMCID:: PMC11137027

Abstract Article PDF–4.1M

Select item 107569322.

SMARCA4 mutation causes human otosclerosis and a similar phenotype in mice

Max Drabkin, Matan M. Jean, Yael Noy, Daniel Halperin, Yuval Yogev, Ohad Wormser, Regina Proskorovsky-Ohayon, Vadim Dolgin, Noam Levaot, Vlad Brumfeld, Shira Ovadia, Mor Kishner, Udi Kazenell, Karen B. Avraham, Ilan Shelef, Ohad S. Birk

J Med Genet. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: J Med Genet. 2024 Jan 19; 61(2): 117–124. Published online 2024 Jan 19. doi: 10.1136/jmg-2023-109264

PMCID:: PMC10756932

Abstract Article PDF–923K

Select item 105102673.

Shuting Li, Congwei Luo, Sijia Chen, Yiyi Zhuang, Yue Ji, Yiqun Zeng, Yao Zeng, Xiaoyang He, Jing Xiao, Huizhen Wang, Xiaowen Chen, Haibo Long, Fenfen Peng

J Transl Med. 2023; 21: 639. Published online 2023 Sep 19. doi: 10.1186/s12967-023-04469-w

PMCID:: PMC10510267

Abstract Article PDF–3.0M

Select item 101543614.

Generation of new transgenic SMARCA4‐deficient mouse models results in neuromuscular weakness and paralysis of limbs

Sina Neyazi, Lea Altendorf, Dora Schwetje, Carolin Göbel, Melanie Schoof, Dörthe Holdhof, Ulrich Schüller

Brain Pathol. 2023 May; 33(3): e13146. Published online 2022 Dec 29. doi: 10.1111/bpa.13146

PMCID:: PMC10154361

Article PDF–346K

Select item 83589635.

Wangqiu Gong, Congwei Luo, Fenfen Peng, Jing Xiao, Yiqun Zeng, Bohui Yin, Xiaowen Chen, Shuting Li, Xiaoyang He, Yanxia Liu, Huihui Cao, Jiangping Xu, Haibo Long

Clin Sci (Lond) 2021 Aug; 135(15): 1873–1895. Published online 2021 Aug 6. doi: 10.1042/CS20210447

PMCID:: PMC8358963

Abstract Article PDF–5.0M

Select item 83158936.

Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation

BongWoo Kim, Yi Luo, Xiaoming Zhan, Zilai Zhang, Xuanming Shi, Jiaqing Yi, Zhenyu Xuan, Jiang Wu

Cell Rep. Author manuscript; available in PMC 2021 Jul 27.

Published in final edited form as: Cell Rep. 2021 Jul 13; 36(2): 109357. doi: 10.1016/j.celrep.2021.109357

PMCID:: PMC8315893

Abstract Article PDF–2.5M

Select item 80124937.

BRG1 Links TLR4 Trans-Activation to LPS-Induced SREBP1a Expression and Liver Injury

Wenhui Dong, Yuwen Zhu, Yangxi Zhang, Zhiwen Fan, Ziyu Zhang, Xiangshan Fan, Yong Xu

Front Cell Dev Biol. 2021; 9: 617073. Published online 2021 Mar 18. doi: 10.3389/fcell.2021.617073

PMCID:: PMC8012493

Abstract Article PDF–4.2M

Select item 79473038.

The Chromatin Remodeling Protein BRG1 Regulates SREBP Maturation by Activating SCAP Transcription in Hepatocytes

Ming Kong, Yuwen Zhu, Jing Shao, Zhiwen Fan, Yong Xu

Front Cell Dev Biol. 2021; 9: 622866. Published online 2021 Feb 25. doi: 10.3389/fcell.2021.622866

PMCID:: PMC7947303

Abstract Article PDF–4.5M

Select item 77907519.

Brg1 restrains the pro-inflammatory properties of ILC3s and modulates intestinal immunity

Xinyi Qi, Jinxin Qiu, Jiali Chang, Yan Ji, Qi Yang, Guoliang Cui, Liming Sun, Qian Chai, Jun Qin, Ju Qiu

Mucosal Immunol. 2021; 14(1): 38–52. Published online 2020 Jul 1. doi: 10.1038/s41385-020-0317-3

Correction in:: Mucosal Immunol. 2021; 14(1): 277.

PMCID:: PMC7790751

Abstract Article PDF–4.5M

Select item 736885710.

Dual roles of chromatin remodeling protein BRG1 in angiotensin II-induced endothelial–mesenchymal transition

Zilong Li, Xiaochen Kong, Yuanyuan Zhang, Yangxi Zhang, Liming Yu, Junli Guo, Yong Xu

Cell Death Dis. 2020 Jul; 11(7): 549. Published online 2020 Jul 18. doi: 10.1038/s41419-020-02744-y

PMCID:: PMC7368857

Abstract Article PDF–3.1M

Select item 724303711.

Zhiwen Fan, Ming Kong, Min Li, Wenxuan Hong, Xiangshan Fan, Yong Xu

Front Cell Dev Biol. 2020; 8: 259. Published online 2020 May 15. doi: 10.3389/fcell.2020.00259

PMCID:: PMC7243037

Abstract Article PDF–6.2M

Select item 723774012.

Activation of TWIST Transcription by Chromatin Remodeling Protein BRG1 Contributes to Liver Fibrosis in Mice

Wenhui Dong, Ming Kong, Yuwen Zhu, Yang Shao, Dongmei Wu, Jun Lu, Junli Guo, Yong Xu

Front Cell Dev Biol. 2020; 8: 340. Published online 2020 May 13. doi: 10.3389/fcell.2020.00340

PMCID:: PMC7237740

Abstract Article PDF–7.9M

Select item 684293513.

The Chromatin Remodeler Brg1 Integrates ROS Production and Endothelial-Mesenchymal Transition to Promote Liver Fibrosis in Mice

Zilong Li, Baoyu Chen, Wenhui Dong, Ming Kong, Yang Shao, Zhiwen Fan, Liming Yu, Dongmei Wu, Jun Lu, Junli Guo, Yong Xu

Front Cell Dev Biol. 2019; 7: 245. Published online 2019 Oct 23. doi: 10.3389/fcell.2019.00245

PMCID:: PMC6842935

Abstract Article PDF–5.8M

Select item 553431414.

Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects

Mian Ge, Chaojin Chen, Weifeng Yao, Shaoli Zhou, Fei Huang, Jun Cai, Ziqing Hei

Oxid Med Cell Longev. 2017; 2017: 8787392. Published online 2017 Jul 16. doi: 10.1155/2017/8787392

PMCID:: PMC5534314

Abstract Article PDF–3.9M

Select item 537348015.

SMARCA4 ATPase mutations disrupt direct eviction of PRC1 from chromatin

Benjamin Z. Stanton, Courtney Hodges, Joseph P. Calarco, Simon M. G. Braun, Wai Lim Ku, Cigall Kadoch, Keji Zhao, Gerald R. Crabtree

Nat Genet. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Nat Genet. 2017 Feb; 49(2): 282–288. Published online 2016 Dec 12. doi: 10.1038/ng.3735

PMCID:: PMC5373480

Abstract Article PDF–2.3M

Select item 437819716.

Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation

Nilotpal Roy, Shivani Malik, Karina E. Villanueva, Atsushi Urano, Xinyuan Lu, Guido Von Figura, E. Scott Seeley, David W. Dawson, Eric A. Collisson, Matthias Hebrok

Genes Dev. 2015 Mar 15; 29(6): 658–671. doi: 10.1101/gad.256628.114

PMCID:: PMC4378197

Abstract Article PDF–639K

Select item 409179217.

Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine

Aliaksei Z. Holik, Madeleine Young, Joanna Krzystyniak, Geraint T. Williams, Daniel Metzger, Boris Y. Shorning, Alan R. Clarke

PLoS Genet. 2014 Jul; 10(7): e1004453. Published online 2014 Jul 10. doi: 10.1371/journal.pgen.1004453

PMCID:: PMC4091792

Abstract Article PDF–1.3M

Select item 403285618.

Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis

Catia Attanasio, Alex S. Nord, Yiwen Zhu, Matthew J. Blow, Simon C. Biddie, Eric M. Mendenhall, Jesse Dixon, Crystal Wright, Roya Hosseini, Jennifer A. Akiyama, Amy Holt, Ingrid Plajzer-Frick, Malak Shoukry, Veena Afzal, Bing Ren, Bradley E. Bernstein, Edward M. Rubin, Axel Visel, Len A. Pennacchio

Genome Res. 2014 Jun; 24(6): 920–929. doi: 10.1101/gr.168930.113