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Select item 83311861.

EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence

Jeremie Gautheron, Christophe Morisseau, Wendy K Chung, Jamila Zammouri, Martine Auclair, Genevieve Baujat, Emilie Capel, Celia Moulin, Yuxin Wang, Jun Yang, Bruce D Hammock, Barbara Cerame, Franck Phan, Bruno Fève, Corinne Vigouroux, Fabrizio Andreelli, Isabelle Jeru

eLife. 2021; 10: e68445. Published online 2021 Aug 3. doi: 10.7554/eLife.68445

PMCID:: PMC8331186

Article PDF–4.4M

Select item 69151582.

Increased Soluble Epoxide Hydrolase in Human Gestational Tissues from Pregnancies Complicated by Acute Chorioamnionitis

Tai-Ho Hung, Szu-Fu Chen, Chun-Hu Wu, Chuan-Chi Kao, Chung-Pu Wu

Mediators Inflamm. 2019; 2019: 8687120. Published online 2019 Dec 5. doi: 10.1155/2019/8687120

PMCID:: PMC6915158

Article PDF–1.9M

Select item 67090723.

The effect on congenital heart diseases of maternal EPHX1 polymorphisms modified by polycyclic aromatic hydrocarbons exposure

Jing Tao, Nana Li, Zhen Liu, Ying Deng, Xiaohong Li, Ming Chen, Jing Yu, Jun Zhu, Ping Yu, Yanping Wang

Medicine (Baltimore) 2019 Jul; 98(30): e16556. Published online 2019 Jul 26. doi: 10.1097/MD.0000000000016556

PMCID:: PMC6709072

Article PDF–206K

Select item 65492554.

Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population

Yudan Lv, Xiangyu Zheng, Mingchao Shi, Zan Wang, Li Cui

BMC Neurol. 2019; 19: 114. Published online 2019 Jun 4. doi: 10.1186/s12883-019-1308-4

PMCID:: PMC6549255

Article PDF–1.3M

Select item 55674875.

The Association Between Epoxide Hydrolase Genetic Variant and Effectiveness of Nicotine Replacement Therapy in a Han Chinese Population

Fan Wang, Yanlong Liu, Song Guo, Dafang Chen, Hongqiang Sun

Neurosci Bull. 2016 Dec; 32(6): 545–546. Published online 2016 Oct 25. doi: 10.1007/s12264-016-0074-1

PMCID:: PMC5567487

Article PDF–307K

Select item 48680956.

Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants

Christopher Hassett, Lauri Aicher, Jaspreet S. Sidhu, Curtis J. Omiecinski

Hum Mol Genet. Author manuscript; available in PMC 2016 May 16.

Published in final edited form as: Hum Mol Genet. 1994 Mar; 3(3): 421–428. doi: 10.1093/hmg/3.3.421

Correction in:: Hum Mol Genet, volume 3 on page 1214

PMCID:: PMC4868095

Article PDF–299K

Select item 46120257.

Epoxide hydrolase Tyr113His polymorphism is not associated with susceptibility to esophageal squamous cell carcinoma in population of North China

Jian-Hui Zhang, Xia Jin, Yan Li, Rui Wang, Wei Guo, Na Wang, Deng-Gui Wen, Zhi-Feng Chen, Gang Kuang, Li-Zhen Wei, Shi-Jie Wang

World J Gastroenterol. 2003 Dec 15; 9(12): 2654–2657. Published online 2003 Dec 15. doi: 10.3748/wjg.v9.i12.2654

PMCID:: PMC4612025

Article PDF–91K

Select item 45447548.

Microsomal Epoxide Hydrolase 1 (EPHX1): Gene, Structure, Function, and Role in Human Disease

Radka Václavíková, David J Hughes, Pavel Souček

Gene. Author manuscript; available in PMC 2016 Oct 15.

Published in final edited form as: Gene. 2015 Oct 15; 571(1): 1–8. Published online 2015 Jul 26. doi: 10.1016/j.gene.2015.07.071

PMCID:: PMC4544754

Article PDF–460K

Select item 44375219.

Effect of N-acetylcysteine in COPD patients with different microsomal epoxide hydrolase genotypes

Jian-Qing Zhang, Jia-Qiang Zhang, Hua Liu, Zhi-Huan Zhao, Li-Zhou Fang, Ling Liu, Wei-Ping Fu, Jing-Kui Shu, Jia-Gang Feng, Lu-Ming Dai

Int J Chron Obstruct Pulmon Dis. 2015; 10: 917–923. Published online 2015 May 13. doi: 10.2147/COPD.S79710

PMCID:: PMC4437521

Article PDF–380K

Select item 441453710.

Systematic Review and Meta-Analysis of the Relationship between EPHX1 Polymorphisms and the Risk of Head and Neck Cancer

Hong Chen, Lin Ge, Qiuli Sui, Mei Lin

PLoS One. 2015; 10(4): e0123347. Published online 2015 Apr 29. doi: 10.1371/journal.pone.0123347

PMCID:: PMC4414537

Article PDF–3.3M

Select item 418966411.

Quantitative assessment of the influence of EPHX1 gene polymorphisms and cancer risk: a meta-analysis with 94,213 subjects

Xiaoqin Yang, Yubing Wang, Guiping Wang

J Exp Clin Cancer Res. 2014; 33(1): 82. Published online 2014 Sep 28. doi: 10.1186/s13046-014-0082-9

PMCID:: PMC4189664

Article PDF–1.4M

Select item 409189612.

Alternative Promoters Determine Tissue-Specific Expression Profiles of the Human Microsomal Epoxide Hydrolase Gene (EPHX1)

Shun-Hsin Liang, Christopher Hassett, Curtis J. Omiecinski

Mol Pharmacol. Author manuscript; available in PMC 2014 Jul 10.

Published in final edited form as: Mol Pharmacol. 2005 Jan; 67(1): 220–230. Published online 2004 Oct 1. doi: 10.1124/mol.104.005579

PMCID:: PMC4091896

Article PDF–1.6M

Select item 409189113.

Variability in Human Sensitivity to 1,3-Butadiene: Influence of Polymorphisms in the 5′-Flanking Region of the Microsomal Epoxide Hydrolase Gene (EPHX1)

Sherif Z. Abdel-Rahman, Marinel M. Ammenheuser, Curtis J. Omiecinski, Jeffrey K. Wickliffe, Judah I. Rosenblatt, Jonathan B. Ward, Jr.

Toxicol Sci. Author manuscript; available in PMC 2014 Jul 10.

Published in final edited form as: Toxicol Sci. 2005 May; 85(1): 624–631. Published online 2005 Feb 16. doi: 10.1093/toxsci/kfi115

PMCID:: PMC4091891

Article PDF–415K

Select item 409187714.

Functional analysis of human microsomal epoxide hydrolase genetic variants

Vinayak P. Hosagrahara, Allan E. Rettie, Christopher Hassett, Curtis J. Omiecinski

Chem Biol Interact. Author manuscript; available in PMC 2014 Jul 10.

Published in final edited form as: Chem Biol Interact. 2004 Nov 20; 150(2): 149–159. doi: 10.1016/j.cbi.2004.07.004

PMCID:: PMC4091877

Article PDF–423K

Select item 400955115.

Association between esophageal cancer risk and EPHX1 polymorphisms: A meta-analysis

Qin-Tao Li, Wei Kang, Man Wang, Jun Yang, Yang Zuo, Wei Zhang, Dan-Ke Su

World J Gastroenterol. 2014 May 7; 20(17): 5124–5130. Published online 2014 May 7. doi: 10.3748/wjg.v20.i17.5124

PMCID:: PMC4009551

Article PDF–742K

Select item 391488316.

Quantitative Methylation Level of the EPHX1 Promoter in Peripheral Blood DNA Is Associated with Polycystic Ovary Syndrome

Qing Sang, Xin Li, Haojue Wang, Huan Wang, Shaozhen Zhang, Ruizhi Feng, Yao Xu, Qiaoli Li, Xinzhi Zhao, Qinghe Xing, Li Jin, Lin He, Lei Wang

PLoS One. 2014; 9(2): e88013. Published online 2014 Feb 5. doi: 10.1371/journal.pone.0088013

PMCID:: PMC3914883

Article PDF–739K

Select item 385552717.

Maternal Variation in EPHX1, a Xenobiotic Metabolism Gene, Is Associated with Childhood Medulloblastoma: An Exploratory Case-Parent Triad Study

Philip J. Lupo, Darryl Nousome, M. Fatih Okcu, Murali Chintagumpala, Michael E. Scheurer

Pediatr Hematol Oncol. Author manuscript; available in PMC 2013 Dec 7.

Published in final edited form as: Pediatr Hematol Oncol. 2012 Nov; 29(8): 10.3109/08880018.2012.722747. Published online 2012 Sep 20. doi: 10.3109/08880018.2012.722747