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Select item 108659801.

Inhibiting influenza virus transmission using a broadly acting neuraminidase that targets host sialic acids in the upper respiratory tract

Mila B. Ortigoza, Catherina L. Mobini, Hedy L. Rocha, Stacey Bartlett, Cynthia A. Loomis, Jeffrey N. Weiser

mBio. 2024 Feb; 15(2): e02203-23. Published online 2024 Jan 11. doi: 10.1128/mbio.02203-23

PMCID:: PMC10865980

Abstract Article PDF–4.8M

Select item 108596282.

Platelet-localized ST6Gal1 does not impact IgG sialylation

Leandre M Glendenning, Julie Y Zhou, Emily N Kukan, Chao Gao, Richard D Cummings, Smita Joshi, Sidney W Whiteheart, Brian A Cobb

Glycobiology. 2023 Nov; 33(11): 943–953. Published online 2023 Jun 28. doi: 10.1093/glycob/cwad052

PMCID:: PMC10859628

Abstract Article PDF–2.5M

Select item 96755603.

α2,6 Sialylation mediated by ST6GAL1 promotes glioblastoma growth

Sajina GC, Kaysaw Tuy, Lucas Rickenbacker, Robert Jones, Asmi Chakraborty, C. Ryan Miller, Elizabeth A. Beierle, Vidya Sagar Hanumanthu, Anh N. Tran, James A. Mobley, Susan L. Bellis, Anita B. Hjelmeland

JCI Insight. 2022 Nov 8; 7(21): e158799. Published online 2022 Nov 8. doi: 10.1172/jci.insight.158799

PMCID:: PMC9675560

Abstract Article PDF–9.3M

Select item 93875074.

ST6Gal1 in plasma is dispensable for IgG sialylation

Douglas M Oswald, Sylvain D Lehoux, Julie Y Zhou, Leandre M Glendenning, Richard D Cummings, Brian A Cobb

Glycobiology. 2022 Sep; 32(9): 803–813. Published online 2022 Jun 23. doi: 10.1093/glycob/cwac039

PMCID:: PMC9387507

Abstract Article PDF–1.8M

Select item 73057995.

The sialyltransferase ST6GAL1 protects against radiation-induced gastrointestinal damage

Patrick R Punch, Eric E Irons, Charles T Manhardt, Himangi Marathe, Joseph T Y Lau

Glycobiology. 2020 Jul; 30(7): 446–453. Published online 2020 Jan 2. doi: 10.1093/glycob/cwz108

PMCID:: PMC7305799

Abstract Article PDF–818K

Select item 71909766.

Blood-Borne ST6GAL1 Regulates Immunoglobulin Production in B Cells

Eric E. Irons, Patrick R. Punch, Joseph T. Y. Lau

Front Immunol. 2020; 11: 617. Published online 2020 Apr 23. doi: 10.3389/fimmu.2020.00617

PMCID:: PMC7190976

Abstract Article PDF–4.8M

Select item 69432367.

Involvement of ST6Gal I‐mediated α2,6 sialylation in myoblast proliferation and differentiation

Caroline Vergé, Amel Bouchatal, Frédéric Chirat, Yann Guérardel, Abderrahman Maftah, Jean‐Michel Petit

FEBS Open Bio. 2020 Jan; 10(1): 56–69. Published online 2019 Dec 10. doi: 10.1002/2211-5463.12745

PMCID:: PMC6943236

Abstract Article PDF–4.6M

Select item 61597448.

Systemic ST6Gal-1 Is a Pro-survival Factor for Murine Transitional B Cells

Eric E. Irons, Joseph T. Y. Lau

Front Immunol. 2018; 9: 2150. Published online 2018 Sep 20. doi: 10.3389/fimmu.2018.02150

PMCID:: PMC6159744

Abstract Article PDF–3.7M

Select item 53131009.

The Inhibitory Role of α2,6-Sialylation in Adipogenesis

Tomoko Kaburagi, Yasuhiko Kizuka, Shinobu Kitazume, Naoyuki Taniguchi

J Biol Chem. 2017 Feb 10; 292(6): 2278–2286. Published online 2016 Dec 28. doi: 10.1074/jbc.M116.747667

PMCID:: PMC5313100

Abstract Article PDF–1.6M

Select item 482204910.

Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis

Yuhsuke Ohmi, Wataru Ise, Akira Harazono, Daisuke Takakura, Hidehiro Fukuyama, Yoshihiro Baba, Masashi Narazaki, Hirofumi Shoda, Nobunori Takahashi, Yuki Ohkawa, Shuting Ji, Fumihiro Sugiyama, Keishi Fujio, Atsushi Kumanogoh, Kazuhiko Yamamoto, Nana Kawasaki, Tomohiro Kurosaki, Yoshimasa Takahashi, Koichi Furukawa

Nat Commun. 2016; 7: 11205. Published online 2016 Apr 5. doi: 10.1038/ncomms11205

PMCID:: PMC4822049

Abstract Article PDF–1.5M

Select item 394537711.

Remodeling of Marrow Hematopoietic Stem and Progenitor Cells by Non-self ST6Gal-1 Sialyltransferase

Mehrab Nasirikenari, Lucas Veillon, Christine C. Collins, Parastoo Azadi, Joseph T. Y. Lau

J Biol Chem. 2014 Mar 7; 289(10): 7178–7189. Published online 2014 Jan 14. doi: 10.1074/jbc.M113.508457

PMCID:: PMC3945377

Abstract Article PDF–1.8M

Select item 334611312.

Anti-inflammatory IgG Production Requires Functional P1 Promoter in β-Galactoside α2,6-Sialyltransferase 1 (ST6Gal-1) Gene

Mark B. Jones, Mehrab Nasirikenari, Amit A. Lugade, Yasmin Thanavala, Joseph T. Y. Lau

J Biol Chem. 2012 May 4; 287(19): 15365–15370. Published online 2012 Mar 15. doi: 10.1074/jbc.M112.345710

PMCID:: PMC3346113

Abstract Article PDF–783K

Select item 291573613.

Role for Hepatic and Circulatory ST6Gal-1 Sialyltransferase in Regulating Myelopoiesis

Mark B. Jones, Mehrab Nasirikenari, Li Feng, Marina T. Migliore, Kyoung-Soo Choi, Latif Kazim, Joseph T. Y. Lau

J Biol Chem. 2010 Aug 6; 285(32): 25009–25017. Published online 2010 Jun 7. doi: 10.1074/jbc.M110.104406

PMCID:: PMC2915736

Abstract Article PDF–2.2M

Select item 283012814.

Altered eosinophil profile in mice with ST6Gal-1 deficiency: an additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation

Mehrab Nasirikenari, E. V. Chandrasekaran, Khushi L. Matta, Brahm H. Segal, Paul N. Bogner, Amit A. Lugade, Yasmin Thanavala, James J. Lee, Joseph T. Y. Lau

J Leukoc Biol. 2010 Mar; 87(3): 457–466. Published online 2009 Dec 9. doi: 10.1189/jlb.1108704

PMCID:: PMC2830128

Abstract Article

Select item 273377015.

Disruption of thymopoiesis in ST6Gal I-deficient mice

Julie H Marino, Chibing Tan, Brenda Davis, Eun-Soo Han, Morgan Hickey, Rebecca Naukam, Ashlee Taylor, Kenton S Miller, C Justin Van De Wiele, T Kent Teague

Glycobiology. 2008 Sep; 18(9): 719–726. Published online 2008 Jun 5. doi: 10.1093/glycob/cwn051

PMCID:: PMC2733770

Abstract Article PDF–418K

Select item 189542816.

Altered granulopoietic profile and exaggerated acute neutrophilic inflammation in mice with targeted deficiency in the sialyltransferase ST6Gal I

Mehrab Nasirikenari, Brahm H. Segal, Julie R. Ostberg, Ashlee Urbasic, Joseph T. Lau

Blood. 2006 Nov 15; 108(10): 3397–3405. Prepublished online 2006 Jul 18. doi: 10.1182/blood-2006-04-014779

PMCID:: PMC1895428

Abstract Article

Select item 2251917.

Immune regulation by the ST6Gal sialyltransferase

Thierry Hennet, Daniel Chui, James C. Paulson, Jamey D. Marth

Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8): 4504–4509. doi: 10.1073/pnas.95.8.4504

PMCID:: PMC22519

Abstract Article PDF–292K

Select item 1061943618.

ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression

Nikita Bhalerao, Asmi Chakraborty, Michael P. Marciel, Jihye Hwang, Colleen M. Britain, Austin D. Silva, Isam E. Eltoum, Robert B. Jones, Katie L. Alexander, Lesley E. Smythies, Phillip D. Smith, David K. Crossman, Michael R. Crowley, Boyoung Shin, Laurie E. Harrington, Zhaoqi Yan, Maigen M. Bethea, Chad S. Hunter, Christopher A. Klug, Donald J. Buchsbaum, Susan L. Bellis

JCI Insight. 2023 Oct 9; 8(19): e161563. Published online 2023 Oct 9. doi: 10.1172/jci.insight.161563

PMCID:: PMC10619436

Abstract Article PDF–21M

Select item 992289619.

Long-term consequences of reduced availability and compensatory supplementation of sialylated HMOs on cognitive capabilities

Edoardo Pisa, Alice Traversa, Viviana Caputo, Angela Maria Ottomana, Jonas Hauser, Simone Macrì

Front Cell Neurosci. 2023; 17: 1091890. Published online 2023 Jan 30. doi: 10.3389/fncel.2023.1091890

PMCID:: PMC9922896

Abstract Article PDF–4.4M

Select item 765234220.

Regulation of inflammatory signaling by the ST6Gal-I sialyltransferase

Andrew T. Holdbrooks, Katherine E. Ankenbauer, Jihye Hwang, Susan L. Bellis

PLoS One. 2020; 15(11): e0241850. Published online 2020 Nov 9. doi: 10.1371/journal.pone.0241850

PMCID:: PMC7652342

Abstract Article PDF–3.1M

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